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Volumn 31, Issue 2, 2006, Pages 117-125

XBP1 is critical to protect cells from endoplasmic reticulum stress: Evidence from site-2 protease-deficient Chinese hamster ovary cells

Author keywords

Endoplasmic reticulum; Molecular chaperone; mRNA splicing; Protein folding; Transcription factor

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CIS ACTING ELEMENT; MESSENGER RNA PRECURSOR; PROTEIN IRE1; PROTEINASE; X BOX BINDING PROTEIN 1;

EID: 33846217495     PISSN: 03867196     EISSN: 13473700     Source Type: Journal    
DOI: 10.1247/csf.06016     Document Type: Article
Times cited : (61)

References (36)
  • 1
    • 0037011917 scopus 로고    scopus 로고
    • IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
    • Calfon, M., Zeng, H., Urano, F., Till, J.H., Hubbard, S.R., Harding, H.P., Clark, S.G., and Ron, D. 2002. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature, 415: 92-96.
    • (2002) Nature , vol.415 , pp. 92-96
    • Calfon, M.1    Zeng, H.2    Urano, F.3    Till, J.H.4    Hubbard, S.R.5    Harding, H.P.6    Clark, S.G.7    Ron, D.8
  • 2
    • 0026584271 scopus 로고
    • Protein folding in the cell
    • Gething, M.J. and Sambrook, J. 1992. Protein folding in the cell. Nature, 355: 33-45.
    • (1992) Nature , vol.355 , pp. 33-45
    • Gething, M.J.1    Sambrook, J.2
  • 3
    • 0036437307 scopus 로고    scopus 로고
    • Transcriptional and translational control in the mammalian unfolded protein response
    • Harding, H.P., Calfon, M., Urano, F., Novoa, I., and Ron, D. 2002. Transcriptional and translational control in the mammalian unfolded protein response. Annu. Rev. Cell Dev. Biol., 18: 575-599.
    • (2002) Annu. Rev. Cell Dev. Biol , vol.18 , pp. 575-599
    • Harding, H.P.1    Calfon, M.2    Urano, F.3    Novoa, I.4    Ron, D.5
  • 4
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding, H.P., Novoa, I.I., Zhang, Y., Zeng, H., Wek, R., Schapira, M., and Ron, D. 2000a. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell, 6: 1099-1108.
    • (2000) Mol. Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6    Ron, D.7
  • 5
    • 0033634641 scopus 로고    scopus 로고
    • Perk is essential for translational regulation and cell survival during the unfolded protein response
    • Harding, H.P., Zhang, Y., Bertolotti, A., Zeng, H., and Ron, D. 2000b. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol. Cell, 5: 897-904.
    • (2000) Mol. Cell , vol.5 , pp. 897-904
    • Harding, H.P.1    Zhang, Y.2    Bertolotti, A.3    Zeng, H.4    Ron, D.5
  • 6
    • 0028087833 scopus 로고
    • Somatic cell genetic and biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression
    • Hasan, M.T., Chang, C.C., and Chang, T.Y. 1994. Somatic cell genetic and biochemical characterization of cell lines resulting from human genomic DNA transfections of Chinese hamster ovary cell mutants defective in sterol-dependent activation of sterol synthesis and LDL receptor expression. Somat. Cell Mol. Genet., 20: 183-194.
    • (1994) Somat. Cell Mol. Genet , vol.20 , pp. 183-194
    • Hasan, M.T.1    Chang, C.C.2    Chang, T.Y.3
  • 7
    • 0035310752 scopus 로고    scopus 로고
    • Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response
    • Haze, K., Okada, T., Yoshida, H., Yanagi, H., Yura, T., Negishi, M., and Mori, K. 2001. Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response. Biochem. J., 355: 19-28.
    • (2001) Biochem. J , vol.355 , pp. 19-28
    • Haze, K.1    Okada, T.2    Yoshida, H.3    Yanagi, H.4    Yura, T.5    Negishi, M.6    Mori, K.7
  • 8
    • 0032693671 scopus 로고    scopus 로고
    • Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
    • Haze, K., Yoshida, H., Yanagi, H., Yura, T., and Mori, K. 1999. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol. Biol. Cell, 10: 3787-3799.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 3787-3799
    • Haze, K.1    Yoshida, H.2    Yanagi, H.3    Yura, T.4    Mori, K.5
  • 9
    • 0026659680 scopus 로고
    • The endoplasmic reticulum as a protein folding compartment
    • Helenius, A., Marquardt, T., and Braakman, I. 1992. The endoplasmic reticulum as a protein folding compartment. Trends Cell Biol., 2: 227-231.
    • (1992) Trends Cell Biol , vol.2 , pp. 227-231
    • Helenius, A.1    Marquardt, T.2    Braakman, I.3
  • 10
    • 0037021416 scopus 로고    scopus 로고
    • Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation
    • Kaneko, M., Ishiguro, M., Niinuma, Y., Uesugi, M., and Nomura, Y. 2002. Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation. FEBS Lett., 532: 147-152.
    • (2002) FEBS Lett , vol.532 , pp. 147-152
    • Kaneko, M.1    Ishiguro, M.2    Niinuma, Y.3    Uesugi, M.4    Nomura, Y.5
  • 11
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
    • Kaufman, R.J. 1999. Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev., 13: 1211-1233.
    • (1999) Genes Dev , vol.13 , pp. 1211-1233
    • Kaufman, R.J.1
  • 12
    • 0030949874 scopus 로고    scopus 로고
    • ER quality control: The cytoplasmic connection
    • Kopito, R.R. 1997. ER quality control: the cytoplasmic connection. Cell, 88: 427-430.
    • (1997) Cell , vol.88 , pp. 427-430
    • Kopito, R.R.1
  • 13
    • 0037083755 scopus 로고    scopus 로고
    • IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
    • Lee, K., Tirasophon, W., Shen, X., Michalak, M., Prywes, R., Okada, T., Yoshida, H., Mori, K., and Kaufman, R.J. 2002. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev., 16: 452-466.
    • (2002) Genes Dev , vol.16 , pp. 452-466
    • Lee, K.1    Tirasophon, W.2    Shen, X.3    Michalak, M.4    Prywes, R.5    Okada, T.6    Yoshida, H.7    Mori, K.8    Kaufman, R.J.9
  • 14
    • 26244431960 scopus 로고    scopus 로고
    • Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane
    • Lilley, B.N. and Ploegh, H.L. 2005. Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane. Proc. Natl. Acad. Sci. USA, 102: 14296-14301.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 14296-14301
    • Lilley, B.N.1    Ploegh, H.L.2
  • 15
    • 0034716887 scopus 로고    scopus 로고
    • Tripartite management of unfolded proteins in the endoplasmic reticulum
    • Mori, K. 2000. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell, 101: 451-454.
    • (2000) Cell , vol.101 , pp. 451-454
    • Mori, K.1
  • 16
    • 0042812063 scopus 로고    scopus 로고
    • Frame switch splicing and regulated intramembrane proteolysis: Key words to understand the unfolded protein response
    • Mori, K. 2003. Frame switch splicing and regulated intramembrane proteolysis: key words to understand the unfolded protein response. Traffic, 4: 519-528.
    • (2003) Traffic , vol.4 , pp. 519-528
    • Mori, K.1
  • 17
    • 33846201752 scopus 로고    scopus 로고
    • Analysis of ATF6 activation in site-2 protease-deficient Chinese hamster ovary cells
    • Nadanaka, S., Yoshida, H., Sato, R., and Mori, K. 2006. Analysis of ATF6 activation in site-2 protease-deficient Chinese hamster ovary cells. Cell Struct. Funct., 31: 109-116.
    • (2006) Cell Struct. Funct , vol.31 , pp. 109-116
    • Nadanaka, S.1    Yoshida, H.2    Sato, R.3    Mori, K.4
  • 18
    • 31944450850 scopus 로고    scopus 로고
    • Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
    • Oda, Y., Okada, T., Yoshida, H., Kaufman, R.J., Nagata, K., and Mori, K. 2006. Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J. Cell Biol., 172: 383-393.
    • (2006) J. Cell Biol , vol.172 , pp. 383-393
    • Oda, Y.1    Okada, T.2    Yoshida, H.3    Kaufman, R.J.4    Nagata, K.5    Mori, K.6
  • 19
    • 0041731803 scopus 로고    scopus 로고
    • A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6
    • Okada, T., Haze, K., Nadanaka, S., Yoshida, H., Seidah, N.G., Hirano, Y., Sato, R., Negishi, M., and Mori, K. 2003. A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6. J. Biol. Chem., 278: 31024-31032.
    • (2003) J. Biol. Chem , vol.278 , pp. 31024-31032
    • Okada, T.1    Haze, K.2    Nadanaka, S.3    Yoshida, H.4    Seidah, N.G.5    Hirano, Y.6    Sato, R.7    Negishi, M.8    Mori, K.9
  • 20
    • 0036713724 scopus 로고    scopus 로고
    • Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response
    • Okada, T., Yoshida, H., Akazawa, R., Negishi, M., and Mori, K. 2002. Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response. Biochem. J., 366: 585-594.
    • (2002) Biochem. J , vol.366 , pp. 585-594
    • Okada, T.1    Yoshida, H.2    Akazawa, R.3    Negishi, M.4    Mori, K.5
  • 21
    • 13244265787 scopus 로고    scopus 로고
    • A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation
    • Olivari, S., Galli, C., Alanen, H., Ruddock, L., and Molinari, M. 2005. A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation. J. Biol. Chem., 280: 2424-2428.
    • (2005) J. Biol. Chem , vol.280 , pp. 2424-2428
    • Olivari, S.1    Galli, C.2    Alanen, H.3    Ruddock, L.4    Molinari, M.5
  • 22
    • 0035370949 scopus 로고    scopus 로고
    • Intracellular signaling from the endoplasmic reticulum to the nucleus: The unfolded protein response in yeast and mammals
    • Patil, C. and Walter, P. 2001. Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals. Curr. Opinion Cell Biol., 13: 349-356.
    • (2001) Curr. Opinion Cell Biol , vol.13 , pp. 349-356
    • Patil, C.1    Walter, P.2
  • 23
    • 0031301274 scopus 로고    scopus 로고
    • Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs
    • Rawson, R.B., Zelenski, N.G., Nijhawan, D., Ye, J., Sakai, J., Hasan, M.T., Chang, T.Y., Brown, M.S., and Goldstein, J.L. 1997. Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs. Mol. Cell, 1: 47-57.
    • (1997) Mol. Cell , vol.1 , pp. 47-57
    • Rawson, R.B.1    Zelenski, N.G.2    Nijhawan, D.3    Ye, J.4    Sakai, J.5    Hasan, M.T.6    Chang, T.Y.7    Brown, M.S.8    Goldstein, J.L.9
  • 25
    • 22244446505 scopus 로고    scopus 로고
    • The mammalian unfolded protein response
    • Schroder, M. and Kaufman, R.J. 2005. The mammalian unfolded protein response. Annu. Rev. Biochem., 74: 739-789.
    • (2005) Annu. Rev. Biochem , vol.74 , pp. 739-789
    • Schroder, M.1    Kaufman, R.J.2
  • 26
    • 0036069980 scopus 로고    scopus 로고
    • ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals
    • Shen, J., Chen, X., Hendershot, L., and Prywes, R. 2002. ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev. Cell, 3: 99-111.
    • (2002) Dev. Cell , vol.3 , pp. 99-111
    • Shen, J.1    Chen, X.2    Hendershot, L.3    Prywes, R.4
  • 27
    • 0036270698 scopus 로고    scopus 로고
    • Retro-translocation of proteins from the endoplasmic reticulum into the cytosol
    • Tsai, B., Ye, Y., and Rapoport, T.A. 2002. Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat. Rev. Mol. Cell Biol., 3: 246-255.
    • (2002) Nat. Rev. Mol. Cell Biol , vol.3 , pp. 246-255
    • Tsai, B.1    Ye, Y.2    Rapoport, T.A.3
  • 28
    • 0034282912 scopus 로고    scopus 로고
    • Activation of ATF6 and an ATF6 DNA Binding Site by the Endoplasmic Reticulum Stress Response
    • Wang, Y., Shen, J., Arenzana, N., Tirasophon, W., Kaufman, R.J., and Prywes, R. 2000. Activation of ATF6 and an ATF6 DNA Binding Site by the Endoplasmic Reticulum Stress Response. J. Biol. Chem., 275: 27013-27020.
    • (2000) J. Biol. Chem , vol.275 , pp. 27013-27020
    • Wang, Y.1    Shen, J.2    Arenzana, N.3    Tirasophon, W.4    Kaufman, R.J.5    Prywes, R.6
  • 29
    • 0034108089 scopus 로고    scopus 로고
    • HRD gene dependence of endoplasmic reticulum-associated degradation
    • Wilhovsky, S., Gardner, R., and Hampton, R. 2000. HRD gene dependence of endoplasmic reticulum-associated degradation. Mol. Biol. Cell, 11: 1697-1708.
    • (2000) Mol. Biol. Cell , vol.11 , pp. 1697-1708
    • Wilhovsky, S.1    Gardner, R.2    Hampton, R.3
  • 30
    • 0034515724 scopus 로고    scopus 로고
    • ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
    • Ye, J., Rawson, R.B., Komuro, R., Chen, X., Dave, U.P., Prywes, R., Brown, M.S., and Goldstein, J.L. 2000. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol. Cell, 6: 1355-1364.
    • (2000) Mol. Cell , vol.6 , pp. 1355-1364
    • Ye, J.1    Rawson, R.B.2    Komuro, R.3    Chen, X.4    Dave, U.P.5    Prywes, R.6    Brown, M.S.7    Goldstein, J.L.8
  • 31
    • 0032509216 scopus 로고    scopus 로고
    • Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins; involvement of basic-leucine zipper transcription factors
    • Yoshida, H., Haze, K., Yanagi, H., Yura, T., and Mori, K. 1998. Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins; involvement of basic-leucine zipper transcription factors. J. Biol. Chem., 273: 33741-33749.
    • (1998) J. Biol. Chem , vol.273 , pp. 33741-33749
    • Yoshida, H.1    Haze, K.2    Yanagi, H.3    Yura, T.4    Mori, K.5
  • 32
    • 0037320265 scopus 로고    scopus 로고
    • A time-dependent phase shift in the mammalian unfolded protein response
    • Yoshida, H., Matsui, T., Hosokawa, N., Kaufman, R.J., Nagata, K., and Mori, K. 2003. A time-dependent phase shift in the mammalian unfolded protein response. Dev. Cell, 4: 265-271.
    • (2003) Dev. Cell , vol.4 , pp. 265-271
    • Yoshida, H.1    Matsui, T.2    Hosokawa, N.3    Kaufman, R.J.4    Nagata, K.5    Mori, K.6
  • 33
    • 0035966269 scopus 로고    scopus 로고
    • XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
    • Yoshida, H., Matsui, T., Yamamoto, A., Okada,T., and Mori, K. 2001a. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell, 107: 881-891.
    • (2001) Cell , vol.107 , pp. 881-891
    • Yoshida, H.1    Matsui, T.2    Yamamoto, A.3    Okada, T.4    Mori, K.5
  • 34
    • 0033815971 scopus 로고    scopus 로고
    • ATF6 activated by proteolysis directly binds in the presence of NF-Y (CBF) to the cis-acting element responsible for the mammalian unfolded protein response
    • Yoshida, H., Okada, T., Haze, K., Yanagi, H., Yura, T., and Mori, K. 2000. ATF6 activated by proteolysis directly binds in the presence of NF-Y (CBF) to the cis-acting element responsible for the mammalian unfolded protein response. Mol. Cell Biol., 20: 6755-6767.
    • (2000) Mol. Cell Biol , vol.20 , pp. 6755-6767
    • Yoshida, H.1    Okada, T.2    Haze, K.3    Yanagi, H.4    Yura, T.5    Mori, K.6
  • 35
    • 0035141230 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6α and 6β that activates the mammalian unfolded protein response
    • Yoshida, H., Okada, T., Haze, K., Yanagi, H., Yura, T., Negishi, M., and Mori, K. 2001b. Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6α and 6β that activates the mammalian unfolded protein response. Mol. Cell Biol., 21: 1239-1248.
    • (2001) Mol. Cell Biol , vol.21 , pp. 1239-1248
    • Yoshida, H.1    Okada, T.2    Haze, K.3    Yanagi, H.4    Yura, T.5    Negishi, M.6    Mori, K.7
  • 36
    • 32644432826 scopus 로고    scopus 로고
    • pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response
    • Yoshida, H., Oku, M., Suzuki, M., and Mori, K. 2006. pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response. J. Cell Biol., 172: 565-575.
    • (2006) J. Cell Biol , vol.172 , pp. 565-575
    • Yoshida, H.1    Oku, M.2    Suzuki, M.3    Mori, K.4


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