Down-regulation of dopamine transporter by iron chelation in vitro is mediated by altered trafficking, not synthesis

Journal of Neurochemistry

Volumn 100, Issue 1, 2007, Pages 167-179

  Wiesinger, Jason A ^a   Buwen, James P ^a   Cifelli, Christopher J ^a   Unger, Erica L ^a   Jones, Byron C ^a   Beard, John L ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Dopamine transporter; Iron chelation; Neuro2a cells; PC12 cells; Protein kinase C; Trafficking

Indexed keywords

DEFEROXAMINE; DOPAMINE TRANSPORTER; IRON; MESSENGER RNA; PROTEIN KINASE C; STAUROSPORINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOTINYLATION; CELL LINE; CELL STRAIN; CELL TYPE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOPAMINE UPTAKE; DOPAMINERGIC TRANSMISSION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; EXPOSURE; FRACTIONATION; GENE EXPRESSION; IRON CHELATION; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SYNTHESIS;

ANIMALS; BIOTINYLATION; BLOTTING, WESTERN; CELL LINE; DEFEROXAMINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; HUMANS; LEUCINE; NEUROBLASTOMA; PROTEIN KINASE C; PROTEIN TRANSPORT; RATS; RNA, MESSENGER; SIDEROPHORES; STAUROSPORINE; SUBCELLULAR FRACTIONS; TIME FACTORS; TRANSFECTION; TRITIUM;

RATTUS;

EID: 33846173945     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04175.x     Document Type: Article

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