메뉴 건너뛰기




Volumn 18, Issue 1, 2007, Pages 129-141

Essential role of chromatin assembly factor-1-mediated rapid nucleosome assembly for DNA replication and cell division in vertebrate cells

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CHROMATIN ASSEMBLY FACTOR 1; CYCLINE; DNA; DNA POLYMERASE; HETEROCHROMATIN PROTEIN 1; PROTEIN; PROTEIN P 150; PROTEIN P48; PROTEIN P60; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

EID: 33846128464     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E06-05-0426     Document Type: Article
Times cited : (74)

References (51)
  • 1
    • 25444478878 scopus 로고    scopus 로고
    • Different roles of N-terminal and C-terminal halves of HIRA in transcription regulation of cell cycle-related genes that contribute to control of vertebrate cell growth
    • Ahmad, A., Kikuchi, H., Takami, Y., and Nakayama, T. (2005). Different roles of N-terminal and C-terminal halves of HIRA in transcription regulation of cell cycle-related genes that contribute to control of vertebrate cell growth. J. Biol. Chem. 280, 32090-32100.
    • (2005) J. Biol. Chem , vol.280 , pp. 32090-32100
    • Ahmad, A.1    Kikuchi, H.2    Takami, Y.3    Nakayama, T.4
  • 2
    • 0036299092 scopus 로고    scopus 로고
    • The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly
    • Ahmad, K., and Henikoff, S. (2002). The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol. Cell 9, 1191-1200.
    • (2002) Mol. Cell , vol.9 , pp. 1191-1200
    • Ahmad, K.1    Henikoff, S.2
  • 4
    • 0035101733 scopus 로고    scopus 로고
    • Dynamic interaction of DNA damage checkpoint protein Rad53 with chromatin assembly factor Asf1
    • Emili, A., Schieltz, D. M., Yates, J. R., 3rd, and Hartwell, L. H. (2001). Dynamic interaction of DNA damage checkpoint protein Rad53 with chromatin assembly factor Asf1. Mol. Cell 7, 13-20.
    • (2001) Mol. Cell , vol.7 , pp. 13-20
    • Emili, A.1    Schieltz, D.M.2    Yates III, J.R.3    Hartwell, L.H.4
  • 5
    • 22344434704 scopus 로고    scopus 로고
    • Histone deposition protein Asf1 maintains DNA replisome integrity and interacts with replication factor C
    • Franco, A. A., Lamn, W. M., Burgers, P. M., and Kaufman, P. D. (2005). Histone deposition protein Asf1 maintains DNA replisome integrity and interacts with replication factor C. Genes Dev. 19, 1365-1375.
    • (2005) Genes Dev , vol.19 , pp. 1365-1375
    • Franco, A.A.1    Lamn, W.M.2    Burgers, P.M.3    Kaufman, P.D.4
  • 8
    • 0030595338 scopus 로고    scopus 로고
    • Chromatin assembly coupled to DNA repair: A new role for chromatin assembly fnctor I
    • Gaillard, P. H., Martini, E. M., Kaufman, P. D., Stillman, B., Moustacchi, E., and Almouzni, G. (1996). Chromatin assembly coupled to DNA repair: a new role for chromatin assembly fnctor I. Cell 86, 887-896.
    • (1996) Cell , vol.86 , pp. 887-896
    • Gaillard, P.H.1    Martini, E.M.2    Kaufman, P.D.3    Stillman, B.4    Moustacchi, E.5    Almouzni, G.6
  • 9
    • 0029971350 scopus 로고
    • The stability of nucleosomes at the replication fork
    • Gasser, R., Koller, T., and Sogo, J. M. (1966). The stability of nucleosomes at the replication fork. J. Mol. Biol. 258, 224-239.
    • (1966) J. Mol. Biol , vol.258 , pp. 224-239
    • Gasser, R.1    Koller, T.2    Sogo, J.M.3
  • 10
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen, M., and Bujard, H. (1992). Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89, 5547-5551.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 11
    • 0027507943 scopus 로고
    • Disruption of the nucleosomes at the replication fork
    • Gruss, C., Wu, J., Koller, T., and Sogo, J. M. (1993). Disruption of the nucleosomes at the replication fork. EMBO J. 12, 4333-4545.
    • (1993) EMBO J , vol.12 , pp. 4333-4545
    • Gruss, C.1    Wu, J.2    Koller, T.3    Sogo, J.M.4
  • 12
    • 0142091385 scopus 로고    scopus 로고
    • Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo
    • Hoek, M., and Stillman, B. (2003). Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo. Proc. Natl. Acad. Sci. USA 100, 12183-12188.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 12183-12188
    • Hoek, M.1    Stillman, B.2
  • 13
    • 0035336971 scopus 로고    scopus 로고
    • Asf1 links Rad53 to control of chromatin assembly
    • Hu, F., Alcasabas, A. A., and Elledge, S. J. (2001). Asf1 links Rad53 to control of chromatin assembly. Genes Dev. 15, 1061-1066.
    • (2001) Genes Dev , vol.15 , pp. 1061-1066
    • Hu, F.1    Alcasabas, A.A.2    Elledge, S.J.3
  • 14
    • 0041440100 scopus 로고    scopus 로고
    • Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes
    • Hudson, D. F., Vagnarelli, P., Gassmann, R., and Earnshaw, W. C. (2003). Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes. Dev. Cell 5, 323-336.
    • (2003) Dev. Cell , vol.5 , pp. 323-336
    • Hudson, D.F.1    Vagnarelli, P.2    Gassmann, R.3    Earnshaw, W.C.4
  • 15
    • 0029011919 scopus 로고
    • The p150 and p60 subunits of chromatin assembly factor I: A molecular link between newly synthesized histones and DNA replication
    • Kaufman, P. D., Kobayashi, R., Kessler, N., and Stillman, B. (1995). The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. Cell 81, 1105-1114.
    • (1995) Cell , vol.81 , pp. 1105-1114
    • Kaufman, P.D.1    Kobayashi, R.2    Kessler, N.3    Stillman, B.4
  • 16
    • 0031043134 scopus 로고    scopus 로고
    • Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-1
    • Kaufman, P. D., Kobayashi, R., and Stillman, B. (1997). Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-1. Genes Dev. 11, 345-357.
    • (1997) Genes Dev , vol.11 , pp. 345-357
    • Kaufman, P.D.1    Kobayashi, R.2    Stillman, B.3
  • 17
    • 0036135016 scopus 로고    scopus 로고
    • Chromatin assembly factor 1 mutants defective for PCNA binding require Asf1/Hir proteins for silencing
    • Krawitz, D. C., Kama, T., and Kaufman, P. D. (2002). Chromatin assembly factor 1 mutants defective for PCNA binding require Asf1/Hir proteins for silencing. Mol. Cell Biol. 22, 614-625.
    • (2002) Mol. Cell Biol , vol.22 , pp. 614-625
    • Krawitz, D.C.1    Kama, T.2    Kaufman, P.D.3
  • 18
    • 0029397731 scopus 로고
    • Chromatin. Nucleosome assembly during DNA replication
    • Krude, T. (1995). Chromatin. Nucleosome assembly during DNA replication. Curr. Biol. 5, 1232-1234.
    • (1995) Curr. Biol , vol.5 , pp. 1232-1234
    • Krude, T.1
  • 19
    • 0033167934 scopus 로고    scopus 로고
    • Chromatin assembly during DNA replication in somatic cells
    • Krude, T. (1999). Chromatin assembly during DNA replication in somatic cells. Eur. J. Biochem. 263, 1-5.
    • (1999) Eur. J. Biochem , vol.263 , pp. 1-5
    • Krude, T.1
  • 20
    • 0034967855 scopus 로고    scopus 로고
    • Chromatin assembly during S phase: Contributions from histone deposition, DNA replication and the cell division cycle
    • Krude, T., and Keller, C. (2001). Chromatin assembly during S phase: contributions from histone deposition, DNA replication and the cell division cycle. Cell Mol. Life Sci. 58, 665-672.
    • (2001) Cell Mol. Life Sci , vol.58 , pp. 665-672
    • Krude, T.1    Keller, C.2
  • 21
    • 0037291130 scopus 로고    scopus 로고
    • Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17
    • Lee, J., Kumagai, A., and Dunphy, W. G. (2003). Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17. Mol. Cell 11, 329-340.
    • (2003) Mol. Cell , vol.11 , pp. 329-340
    • Lee, J.1    Kumagai, A.2    Dunphy, W.G.3
  • 22
    • 0031811883 scopus 로고    scopus 로고
    • Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA
    • Lorain, S., Quivy, J. P., Monier-Gavelle, F., Scamps, C., Lecluse, Y., Almouzni, G., and Lipinski, M. (1998). Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA. Mol. Cell Biol. 18, 5546-5556.
    • (1998) Mol. Cell Biol , vol.18 , pp. 5546-5556
    • Lorain, S.1    Quivy, J.P.2    Monier-Gavelle, F.3    Scamps, C.4    Lecluse, Y.5    Almouzni, G.6    Lipinski, M.7
  • 24
    • 7744243520 scopus 로고    scopus 로고
    • The DNA damage response: Sensing and signaling
    • McGowan, C. H., and Russell, P. (2004). The DNA damage response: sensing and signaling. Curr. Opin. Cell Biol. 16, 629-633.
    • (2004) Curr. Opin. Cell Biol , vol.16 , pp. 629-633
    • McGowan, C.H.1    Russell, P.2
  • 25
    • 0038505671 scopus 로고    scopus 로고
    • Epigenomic replication: Linking epigenetics to DNA replication
    • McNairn, A. J., and Gilbert, D. M. (2003). Epigenomic replication: linking epigenetics to DNA replication. Bioessays 25, 647-656.
    • (2003) Bioessays , vol.25 , pp. 647-656
    • McNairn, A.J.1    Gilbert, D.M.2
  • 26
    • 0035313802 scopus 로고    scopus 로고
    • The ins and outs of nucleosome assembly
    • Mello, J. A., and Almouzni, G. (2001). The ins and outs of nucleosome assembly. Curr. Opin. Genet. Dev. 11, 136-141.
    • (2001) Curr. Opin. Genet. Dev , vol.11 , pp. 136-141
    • Mello, J.A.1    Almouzni, G.2
  • 27
    • 0033212963 scopus 로고    scopus 로고
    • Heterochromatin dynamics in mouse cells: Interaction between chromatin assembly factor I and HP1 proteins
    • Murzina, N., Verreault, A., Laue, E., and Stillman, B. (1999). Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor I and HP1 proteins. Mol. Cell 4, 529-540.
    • (1999) Mol. Cell , vol.4 , pp. 529-540
    • Murzina, N.1    Verreault, A.2    Laue, E.3    Stillman, B.4
  • 28
    • 1642312883 scopus 로고    scopus 로고
    • Silencing of chromatin assembly factor I in human cells leads to cell death and loss of chromatin assembly during DNA synthesis
    • Nabatiyan, A., and Krude, T. (2004). Silencing of chromatin assembly factor I in human cells leads to cell death and loss of chromatin assembly during DNA synthesis. Mol. Cell Biol. 24, 2853-2862.
    • (2004) Mol. Cell Biol , vol.24 , pp. 2853-2862
    • Nabatiyan, A.1    Krude, T.2
  • 29
    • 0036948433 scopus 로고    scopus 로고
    • Toward maintaining the genome: DNA damage and replication checkpoints
    • Nyberg, K. A., Michelson, R. J., Putnam, C. W., and Weinert, T. A. (2002). Toward maintaining the genome: DNA damage and replication checkpoints. Annu. Rev. Genet. 36, 617-656.
    • (2002) Annu. Rev. Genet , vol.36 , pp. 617-656
    • Nyberg, K.A.1    Michelson, R.J.2    Putnam, C.W.3    Weinert, T.A.4
  • 30
    • 4143059590 scopus 로고    scopus 로고
    • A CAF-1 dependent pool of HP1 during heterochromatin duplication
    • Quivy, J. P., Roche, D., Kirschner, D., Tagami, H., Nakatani, Y., and Almouzni, G. (2004). A CAF-1 dependent pool of HP1 during heterochromatin duplication. EMBO J. 23, 3516-3526.
    • (2004) EMBO J , vol.23 , pp. 3516-3526
    • Quivy, J.P.1    Roche, D.2    Kirschner, D.3    Tagami, H.4    Nakatani, Y.5    Almouzni, G.6
  • 31
    • 0036284794 scopus 로고    scopus 로고
    • HIRA is critical for a nucleosome assembly pathway independent of DNA synthesis
    • Ray-Gallet, D., Quivy, J. P., Scamps, C., Martini, E. M., Lipinski, M., and Almouzni, G. (2002). HIRA is critical for a nucleosome assembly pathway independent of DNA synthesis. Mol. Cell 9, 1041-1100.
    • (2002) Mol. Cell , vol.9 , pp. 1041-1100
    • Ray-Gallet, D.1    Quivy, J.P.2    Scamps, C.3    Martini, E.M.4    Lipinski, M.5    Almouzni, G.6
  • 32
    • 0030271391 scopus 로고    scopus 로고
    • Histone acetylation and chromatin assembly: A single escort, multiple dances?
    • Roth, S. Y., and Allis, C. D. (1996). Histone acetylation and chromatin assembly: a single escort, multiple dances? Cell 87, 5-8.
    • (1996) Cell , vol.87 , pp. 5-8
    • Roth, S.Y.1    Allis, C.D.2
  • 33
    • 33744963245 scopus 로고    scopus 로고
    • Asf1 is required for viability and chromatin assembly during DNA replication in vertebrate cells
    • Sanematsu, F., Takami, Y., Barman, H. K., Fukagawa, T., Ono, T., Shibahara, K. I., and Nakayama, T. (2006). Asf1 is required for viability and chromatin assembly during DNA replication in vertebrate cells. J. Biol. Chem. 281, 13817-13827.
    • (2006) J. Biol. Chem , vol.281 , pp. 13817-13827
    • Sanematsu, F.1    Takami, Y.2    Barman, H.K.3    Fukagawa, T.4    Ono, T.5    Shibahara, K.I.6    Nakayama, T.7
  • 34
    • 0033582544 scopus 로고    scopus 로고
    • Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin
    • Shibahara, K., and Stillman, B. (1999). Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin. Cell 96, 575-585.
    • (1999) Cell , vol.96 , pp. 575-585
    • Shibahara, K.1    Stillman, B.2
  • 35
    • 0024372060 scopus 로고
    • Purification and characterization of CAF-1, a human cell factor required for chroniatin assembly during DNA replication in vitro
    • Smith, S., and Stillman, B. (1989). Purification and characterization of CAF-1, a human cell factor required for chroniatin assembly during DNA replication in vitro. Cell 58, 15-25.
    • (1989) Cell , vol.58 , pp. 15-25
    • Smith, S.1    Stillman, B.2
  • 36
    • 0022519177 scopus 로고
    • Chromatin assembly during SV40 DNA replication in vitro
    • Stillman, B. (1986). Chromatin assembly during SV40 DNA replication in vitro. Cell 45, 555-565.
    • (1986) Cell , vol.45 , pp. 555-565
    • Stillman, B.1
  • 37
    • 0742304304 scopus 로고    scopus 로고
    • Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis
    • Tagami, H., Ray-Gallet, D., Almouzni, G., and Nakatani, Y. (2004). Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell 116, 51-61.
    • (2004) Cell , vol.116 , pp. 51-61
    • Tagami, H.1    Ray-Gallet, D.2    Almouzni, G.3    Nakatani, Y.4
  • 38
    • 0033588156 scopus 로고    scopus 로고
    • Chicken histone deacetylase-2 controls the amount of the IgM H-chain at the steps of both transcription of its gene and alternative processing of its pre-mRNA in the DT40 cell line
    • Takami, Y., Kikuchi, H., and Nakayama, T. (1999). Chicken histone deacetylase-2 controls the amount of the IgM H-chain at the steps of both transcription of its gene and alternative processing of its pre-mRNA in the DT40 cell line. J. Biol. Chem. 274, 23977-23990.
    • (1999) J. Biol. Chem , vol.274 , pp. 23977-23990
    • Takami, Y.1    Kikuchi, H.2    Nakayama, T.3
  • 39
    • 0031261489 scopus 로고    scopus 로고
    • A single copy of linker H1 genes is enough for proliferation of the DT40 chicken B cell line, and linker H1 variants participate in regulation of gene expression
    • Takami, Y., and Nakayama, T. (1997). A single copy of linker H1 genes is enough for proliferation of the DT40 chicken B cell line, and linker H1 variants participate in regulation of gene expression. Genes Cells 2, 711-723.
    • (1997) Genes Cells , vol.2 , pp. 711-723
    • Takami, Y.1    Nakayama, T.2
  • 40
    • 0034717022 scopus 로고    scopus 로고
    • N-terminal region, C-terminal region, nuclear export signal, and deacetylation activity of liistone deacetylase-3 are essential for the viability of the DT40 chicken B cell line
    • Takami, Y., and Nakayama, T. (2000). N-terminal region, C-terminal region, nuclear export signal, and deacetylation activity of liistone deacetylase-3 are essential for the viability of the DT40 chicken B cell line. J. Biol. Chem. 275, 16191-16201.
    • (2000) J. Biol. Chem , vol.275 , pp. 16191-16201
    • Takami, Y.1    Nakayama, T.2
  • 41
    • 0033604444 scopus 로고    scopus 로고
    • Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation
    • Takao, N., Kato, H., Mori, R., Morrison, C., Sonada, E., Sun, X., Shimizu, H., Yoshioka, K., Takeda, S., and Yamamoto, K. (1999). Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation. Oncogene 18, 7002-7009.
    • (1999) Oncogene , vol.18 , pp. 7002-7009
    • Takao, N.1    Kato, H.2    Mori, R.3    Morrison, C.4    Sonada, E.5    Sun, X.6    Shimizu, H.7    Yoshioka, K.8    Takeda, S.9    Yamamoto, K.10
  • 43
    • 0342902244 scopus 로고    scopus 로고
    • A truncated form of the human CAF-1 p150 subunil impairs the maintenance of transcriptional gene silencing in mammalian cells
    • Tchenio, T., Casella, J. F., and Heidmann, T. (2001). A truncated form of the human CAF-1 p150 subunil impairs the maintenance of transcriptional gene silencing in mammalian cells. Mol. Cell Biol. 21, 1953-1961.
    • (2001) Mol. Cell Biol , vol.21 , pp. 1953-1961
    • Tchenio, T.1    Casella, J.F.2    Heidmann, T.3
  • 44
    • 0033518179 scopus 로고    scopus 로고
    • The RCAF complex mediates chroniatin assembly during DNA replication and repair
    • Tyler, J. K., Adams, C. R., Chen, S. K., Kobayashi, R., Kamakaka, R. T., and Kadonaga, J. T. (1999). The RCAF complex mediates chroniatin assembly during DNA replication and repair. Nature 402, 555-560.
    • (1999) Nature , vol.402 , pp. 555-560
    • Tyler, J.K.1    Adams, C.R.2    Chen, S.K.3    Kobayashi, R.4    Kamakaka, R.T.5    Kadonaga, J.T.6
  • 45
    • 0037292293 scopus 로고    scopus 로고
    • Histone deposition at the replication fork: A matter of urgency
    • Verreault, A. (2003). Histone deposition at the replication fork: a matter of urgency. Mol. Cell 11, 283-284.
    • (2003) Mol. Cell , vol.11 , pp. 283-284
    • Verreault, A.1
  • 46
    • 0030272047 scopus 로고    scopus 로고
    • Nucleosome assembly by a complex of CAF-1 and acetylatad histones H3/H4
    • Verreault, A., Kaufman, P. D., Kobayashi, R., and Stillman, B. (1996). Nucleosome assembly by a complex of CAF-1 and acetylatad histones H3/H4. Cell 87, 95-104.
    • (1996) Cell , vol.87 , pp. 95-104
    • Verreault, A.1    Kaufman, P.D.2    Kobayashi, R.3    Stillman, B.4
  • 47
    • 0033534613 scopus 로고    scopus 로고
    • Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex
    • Volkmer, E., and Karnitz, L. M. (1999). Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex. J. Biol. Chem. 274, 567-570.
    • (1999) J. Biol. Chem , vol.274 , pp. 567-570
    • Volkmer, E.1    Karnitz, L.M.2
  • 48
    • 0037291295 scopus 로고    scopus 로고
    • Defective S phase chroniatin assembly causes DNA damage, activation of the S phase checkpoint, and S phase arrest
    • Ye, X., Franco, A. A., Santos, H., Nelson, D. M., Kaufman, P. D., and Adams, P. D. (2003). Defective S phase chroniatin assembly causes DNA damage, activation of the S phase checkpoint, and S phase arrest. Mol. Cell 11, 341-351.
    • (2003) Mol. Cell , vol.11 , pp. 341-351
    • Ye, X.1    Franco, A.A.2    Santos, H.3    Nelson, D.M.4    Kaufman, P.D.5    Adams, P.D.6
  • 49
    • 0037415735 scopus 로고    scopus 로고
    • Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects
    • Zachos, C., Rainey, M. D., and Gillespie, D. A. (2003). Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects. EMBO J. 22, 713-723.
    • (2003) EMBO J , vol.22 , pp. 713-723
    • Zachos, C.1    Rainey, M.D.2    Gillespie, D.A.3
  • 50
    • 19944427674 scopus 로고    scopus 로고
    • Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA
    • Zhang, R., et al. (2005). Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev. Cell 8, 19-30.
    • (2005) Dev. Cell , vol.8 , pp. 19-30
    • Zhang, R.1
  • 51
    • 0034967556 scopus 로고    scopus 로고
    • ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
    • Zhao, H., and Piwnica-Worms, H. (2001). ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol. Cell Biol. 21, 4129-4119.
    • (2001) Mol. Cell Biol , vol.21 , pp. 4129-4119
    • Zhao, H.1    Piwnica-Worms, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.