Inhibitory activity of the hypoxia-inducible factor-1 pathway by tartrolone C

Journal of Antibiotics

Volumn 59, Issue 11, 2006, Pages 693-697

  Yamazaki, Yohko ^a   Someno, Tetsuya ^a   Minamiguchi, Kazuhisa ^a   Kawada, Manabu ^a   Momose, Isao ^a   Kinoshita, Naoko ^a   Doi, Hiroyasu ^a   Ikeda, Daishiro ^a  

^a INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

Author keywords

Hypoxia; Hypoxia inducible factor 1; Reporter gene assay; Tartrolone C; X ray crystallography

Indexed keywords

ANTIBIOTIC AGENT; HYPOXIA INDUCIBLE FACTOR 1; LUCIFERASE; NBR 1759 27; TARTROLONE C; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIUM CULTURE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG INHIBITION; DRUG STRUCTURE; GENE CONSTRUCT; HUMAN; HUMAN CELL; HYPOXIA; IC 50; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; STREPTOMYCES; TRANSCRIPTION INITIATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; BLOTTING, WESTERN; CELL HYPOXIA; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INHIBITORY CONCENTRATION 50; MACROLIDES; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OPTICAL ROTATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET; STREPTOMYCES;

MAMMALIA; STREPTOMYCES;

EID: 33846106519     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2006.92     Document Type: Article

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