Future prospects for old chemotherapeutic drugs in the target-specific era; pharmaceutics, combinations, co-drugs and prodrugs with melphalan as an example

Letters in Drug Design and Discovery

Volumn 3, Issue 10, 2006, Pages 695-703

  Wickstrom M ^a   Lovborg H ^a   Gullbo, J ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cancer target; Chemotherapeutics; Melphalan; Prodrugs

Indexed keywords

1,3 DIPALMITOYL 2 (MELPHALANYL)GLYCEROL; ALKYLATING AGENT; AMIFOSTINE; ANTINEOPLASTIC AGENT; BORTEZOMIB; BUTHIONINE SULFOXIMINE; CARMUSTINE; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DEXTRO 2 AMINO BIS[(2 CHLOROETHYL)AMINO] 1,2,3,4 TETRAHYDRO 2 NAPHTOIC ACID; DNA TOPOISOMERASE INHIBITOR; ETOPOSIDE; MELPHALAN; MISONIDAZOLE; MONOCLONAL ANTIBODY; N ACETYL 4 DEXTRO BIS(2 CHLOROETHYL)AMINOPHENYLALANYLVALINE ETHYL ESTER; PEPTIDE HORMONE; PLATINUM DERIVATIVE; PREDNISONE; PRODRUG; PX 478; SARCOLYSIN; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

ALOPECIA; ANOREXIA; ANTINEOPLASTIC ACTIVITY; BONE MARROW TRANSPLANTATION; BREAST CANCER; CANCER CHEMOTHERAPY; CLINICAL TRIAL; COLON CANCER; COLORECTAL CANCER; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; DIARRHEA; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG MECHANISM; DRUG MEGADOSE; DRUG PENETRATION; DRUG POTENTIATION; DRUG TARGETING; GASTROINTESTINAL SYMPTOM; HUMAN; LEUKOPENIA; LIVER CANCER; LIVER VEIN OBSTRUCTION; LYMPHOMA; MELANOMA; MUCOSA INFLAMMATION; MULTIPLE MYELOMA; NAUSEA AND VOMITING; NEUROBLASTOMA; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REVIEW; SARCOMA; SOLID TUMOR; STRUCTURE ANALYSIS; TESTIS CANCER; THROMBOCYTOPENIA; TREATMENT RESPONSE;

EID: 33846093189     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018006778631893     Document Type: Review

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