Peripheral benzodiazepine receptor ligand-melphalan conjugates for potential selective drug delivery to brain tumors

Bioconjugate Chemistry

Volumn 14, Issue 4, 2003, Pages 830-839

  Trapani, Giuseppe ^a   Laquintana, Valentino ^a   Latrofa, Andrea ^a   Ma, Jianguo ^c   Reed, Karin ^c   Serra, Mariangela ^b   Biggio, Giovanni ^b   Liso, Gaetano ^a   Gallo, James M ^c  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BRAIN; CELL CULTURE; DRUG DELIVERY; ESTERS; LIGANDS; TUMORS;

BENZODIAZEPINES; BINDING AFFINITIES; BRAIN TUMORS; DRUG-CONJUGATES; ETHYL ESTERS; GAIN INSIGHT; GLIOMA CELL LINES; MELPHALAN; PHOSPHATE BUFFERS; RECEPTOR LIGANDS;

DEGRADATION;

BENZODIAZEPINE RECEPTOR; FLUNITRAZEPAM; MELPHALAN; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE;

ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DEGRADATION; DRUG RECEPTOR BINDING; DRUG STABILITY; FEMALE; GLIOMA CELL; HUMAN; HUMAN CELL; LIGAND BINDING; MALE; NONHUMAN; RAT; SERUM;

ANIMALIA;

EID: 0038793422     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc034023p     Document Type: Article

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