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Volumn 457, Issue 2, 2007, Pages 252-263

Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1

(2) Caro, Andres A a Cederbaum, Arthur I a

a MOUNT SINAI SCHOOL OF MEDICINE (United States)

Author keywords

Arachidonic acid; Calcium; CYP2E1; Hepatocytes; HepG2; Lipid peroxidation; Mitochondria; Phospholipase A2

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ARACHIDONIC ACID; CALCIUM ION; CYTOCHROME P450 2E1; HYDROLASE; IONOMYCIN; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; POLYUNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM DEPLETION; CALCIUM TRANSPORT; CELL DEATH; CELL MEMBRANE POTENTIAL; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; EXTRACELLULAR CALCIUM; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER CELL; LIVER TOXICITY; MALE; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT;

ALPHA-TOCOPHEROL; ANIMALS; ARACHIDONIC ACID; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CYTOCHROME P-450 CYP2E1; ENZYME ACTIVATION; HEPATOCYTES; INTRACELLULAR SPACE; LIPID PEROXIDATION; MEMBRANE POTENTIAL, MITOCHONDRIAL; PHOSPHOLIPASES A; RATS;

EID: 33846028489 PISSN: 00039861 EISSN: 10960384 Source Type: Journal
DOI: 10.1016/j.abb.2006.10.018 Document Type: Article

Times cited : (32)

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