Phosphoinositide 3-kinase regulates phospholipase Cγ-mediated calcium signaling

Journal of Biological Chemistry

Volumn 273, Issue 37, 1998, Pages 23750-23757

  Rameh, Lucia E ^a   Rhee, Sue Goo ^c   Spokes, Katherine ^a   Kazlauskas, Andrius ^b   Cantley, Lewis C ^a   Cantley, Lloyd G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; INOSITOL TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C; PLECKSTRIN; PROTEIN KINASE; PROTEIN SERINE KINASE; PROTEIN THREONINE KINASE; TRIPHOSPHOINOSITIDE; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME BINDING; LIPID BILAYER; MEMBRANE STABILIZATION; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RECEPTOR BLOCKING; SEQUENCE HOMOLOGY; SIGNAL DETECTION; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; BINDING SITES; CALCIUM; CHROMONES; ENZYME INHIBITORS; HUMANS; ISOENZYMES; KINETICS; MORPHOLINES; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PLATELET-DERIVED GROWTH FACTOR; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 14444287277     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.37.23750     Document Type: Article

References (28)

1. Kundra, V., Escobedo, J. A., Kazlauskas, A., Kim, H. K., Rhee, S. G., Williams, L. T., and Zetter, B. R. (1994) Nature 367, 474-476
2. Derman, M. P., Chen, J. Y., Spokes, K. C., Songyang, Z., and Cantley, L. G. (1996) J. Biol. Chem. 271, 4251-4255
3. Toker, A., and Cantley, L. C. (1997) Nature 387, 673-676
4. Toker, A., Meyer, M., Reddy, K., Falck, J. R., Aneja, R., Aneja, S., Parra, A., Burns, D., Ballas, L, M., and Cantley, L. C. (1994) J. Biol. Chem. 269, 32358-32367
5. Rameh, L. E., Chen, C.-S., and Cantley, L. C. (1995) Cell 83, 821-830
6. Franke, T. F., Kaplan, D. R., Cantley, L. C., and Toker, A. (1997) Science 275, 665-668
7. Stokoe, D., Stephens, L. R., Copeland, T., Gaffney, P. R., Reese, C. B., Painter, G. F., Holmes, A. B., McCormick, F., and Hawkins, P. T. (1997) Science 277, 567-570
8. Alessi, D. R., James, S. R., Downes, C. P., Holmes, A. B., Gaffney, P. R., Reese, C. B., and Cohen, P. (1997) Curr. Biol. 7, 261-269
9. Klarlund, J. K., Guilherme, A., Holik, J. J., Virbasius, J. V., Chawla, A., and Czech, M. P. (1997) Science 275, 1927-1930
10. Falasca, M., Logan, S. K., Lehto, V. P., Baccante, G., Lemmon, M. A., and Schlessinger, J. (1998) EMBO J. 17, 414-422
11. Bae, Y., Cantley, L., Chen, C.-S., Kim, S.-R., Kwon, K.-S., and Rhee, S. (1998) J. Biol. Chem. 273, 4465-4469
12. Nakanishi, S., Catt, K. J., and Balla, T. (1994) J. Biol. Chem. 269, 6528-6535
13. Bonser, R. W., Thompson, N. T., Randall, R. W., Tateson, J. E., Spacey, G. D., Hodson, H. F., and Garland, L. G. (1991) Br. J. Pharmacol. 103, 1237-1241
14. Barker, S. A., Caldwell, K. K., Hall, A., Martinez, A. M., Pfeiffer, J. R., Oliver, J. M., and Wilson, B. S. (1995) Mol. Biol. Cell 6, 1145-1158
15. Vossebeld, P. J. M., Homburg, C. H. E., Schweizer, R. C., Ibarrola, I., Kessler, J., Koenderman, L., Roos, D., and Verhoeven, A. J. (1997) Biochem. J. 323, 87-94
16. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., pp. 17.2-17.44, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
17. Wang, D.-S., and Chen, C.-S. (1996) J. Org. Chem. 61, 5905-5910
18. Valius, M., and Kazlauskas, A. (1993) Cell 73, 321-334
19. Kazlauskas, A., Kashishian, A., Cooper, J. A., and Valius, M. (1992) Mol. Cell. Biol. 12, 2534-2544
20. Valius, M., Bazenet, C., and Kazlauskas, A. (1993) Mol. Cell. Biol. 13, 133-143
21. Kazlauskas, A., Feng, G. S., Pawson, T., and Valius, M. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 6939-6943
22. Seckl, M. J., Seufferlein, T., and Rozengurt, E. (1994) Cancer Res. 54, 6143-6147
23. Jalink, K., van Corven, E. J., and Moolenaar, W. H. (1990) J. Biol. Chem. 265, 12232-12239
24. Rameh, L. E., Arvidsson, A., Carraway, K. L., III, Couvillon, A. D., Rathbun, G., Crompton, A., VanRenterghem, B., Czech, M. P., Ravichandran, K. S., Burakoff, S. J., Wang, D.-S., Chen, C.-S., and Cantley, L. C. (1997) J. Biol. Chem. 272, 22059-22066
25. Klarlund, J. K., Rameh, L. E., Cantley, L. C., Buxton, J. M., Sakelis, C., Patki, V., Corvera, S., and Czech, M. P. (1998) J. Biol. Chem. 273, 1859-1862
26. Cheatham, B., and Kahn, C. R. (1995) Endocr. Rev. 16, 117-142
27. Derman, M. P., Toker, A., Hartwig, J. H., Spokes, K., Falck, J. R., Chen, C.-S., Cantley, L. C., and Cantley, L. G. (1997) J. Biol. Chem. 272, 6465-6470
28. Dolmetsch, R. E., Lewis, R. S., Goodnow, C. C., and Healy, J. I. (1997) Nature 386, 855-858