Pharmaceutical compounds in wastewater: Wetland treatment as a potential solution

TheScientificWorldJournal

Volumn 6, Issue , 2006, Pages 1731-1736

  White, John R ^a   Belmont, Marco A ^a   Metcalfe, Chris D ^b  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b TRENT UNIVERSITY   (Canada)

Author keywords

Constructed wetland; Drugs; Sewage; Water quality

Indexed keywords

BEZAFIBRATE; CAFFEINE; CARBAMAZEPINE; CLOFIBRIC ACID; COTININE; CYCLOPHOSPHAMIDE; DICLOFENAC; DRINKING WATER; FENOPROFEN; FLUOXETINE; GEMFIBROZIL; IBUPROFEN; INDOMETACIN; KETOPROFEN; NAPROXEN; NORFLUOXETINE; PENTOXIFYLLINE; TRIMETHOPRIM;

AQUATIC ENVIRONMENT; EFFLUENT; MICROBIAL DEGRADATION; PHOTODEGRADATION; PHOTOLYSIS; REVIEW; SEWAGE DISPOSAL; SOIL DEGRADATION; WASTE WATER MANAGEMENT; WATER CONTAMINATION; WATER FLOW; WATER TREATMENT; WETLAND;

BIODEGRADATION, ENVIRONMENTAL; ENVIRONMENTAL MONITORING; PHARMACEUTICAL PREPARATIONS; WASTE DISPOSAL, FLUID; WATER POLLUTANTS, CHEMICAL; WETLANDS;

EID: 33846015832     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2006.287     Document Type: Review

References (46)

1. Ternes, T.A. (1998) Occurrence of drugs in German sewage treatment plants and rivers. Water Res. 32, 3245-3260.
2. Ternes, T., Bonerz, M., and Schmidt, T. (2001) Determination of neutral pharmaceuticals in wastewater and rivers by liquid chromatography-electrospray tandem mass spectrometry. J. Chromatogr. A 938, 175-185.
3. Kolpin, D.W., Furlong, E.T., Meyer, M.T., Thurman, E.M., Zaugg, S.D., Barber, L.B., and Buxton, H.T. (2002) Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance. Environ. Sci. Technol. 36, 1202-1211.
4. Boyd, G.R., Reemtsma, H., Grimm, D.A., and Mitra, S. (2003) Pharmaceuticals and personal care products (PPCPs) in surface and treated waters of Louisiana, USA and Ontario, Canada. Sci. Total Environ. 311, 135-149.
5. Tixier, C., Singer, H.P., Oellers, S., and Müller, S.R. (2003) Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters. Environ. Sci. Technol. 37, 1061-1068.
6. Metcalfe, C.D., Miao, X.-S., Hua, W., Letcher, R., and Servos, M. (2004) Pharmaceuticals in the Canadian environment. In Pharmaceuticals in the Environment: Sources, Fate, Effects and Risks. 2nd ed. Kümmerer, K., Ed. Springer-Verlag. pp. 67-87.
7. Bendz, D., Paxéus, N.A., Ginn, T.R., and Loge, F.J. (2005) Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Höje River in Sweden. J. Hazard. Mater. 122, 195-204.
8. Brun, G.L., Bernier, M., Losier, R., Doe, K., Jackman, P., and Lee, H.-B. (2006) Pharmaceutically active compounds in Atlantic Canadian sewage treatment plant effluents and receiving waters, and potential for environmental effects as measured by acute and chronic toxicity. Environ. Toxicol. Chem. 25, 2163-2176.
9. nd ed. Kümmerer, K., Ed. Springer-Verlag. pp.223-231.
10. Oaks, J.L., Giolbert, M., Virani, M.Z., Watson, R.T., Meteyer, C.U., Rideout, B.A., Shivaprasad, H.L., Ahmed, S., Chaudhry, M.J., Arshad, M., Mahmood S., Ali, A., and Khan, A.A. (2004) Diclofenac residues as the cause of vulture population decline in Pakistan. Nature 427, 630-633.
11. Schultz, S., Baral, H.S., Charman, S., Cuningham, A.A., Das, D., Ghalsasi, G.R., Goudar, M.S., Green, R.E., Jones, A., Nighot, P., Pain, D., and Prakash, V. (2004) Diclofenac poisoning is widespread in declining vulture populations across the Indian subcontinent. Proc. Biol. Sci. 271(Suppl 6), S458-S460.
12. Schwaiger, J., Ferling, H., Mallow, U., Wintermayr, H., and Negele, R.D. (2004) Toxic effects of the non-steroidal anti-inflammatory drug diclfenac. Part I: Histopathological alterations and bioaccumulation in rainbow trout. Aquat. Toxicol. 68, 141-150.
13. Triebskorn, R., Casper, H., Heyd, A., Eikemper, R., Kohler, R.-H., and Schwaiger, J. (2004) Toxic effects of the nonsteroidal anti-inflammatory drug diclfenac. Part II. Cytological effects in liver, kidney, gills and intestine of rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 68, 151-166.
14. Mimeault, C., Woodhouse, A.J., Miao, X.-S., Metcalfe, C.D., Moon, T.W., and Trudeau, V.L. (2005) The human lipid regulator, gemfibrozil bioconcentrates and reduces testosterone in the goldfish, Carrasius auratus. Aquat. Toxicol. 73, 44-54.
15. Huggett, D.B., Brooks, B.W., Peterson, B., Foran, C.M., and Schlenk, D. (2002) Toxicity of select beta adrenergic receptor-blocking pharmaceuticals (B-blockers) on aquatic organisms. Arch. Environ. Contam. Toxicol. 43, 229-235.
16. Brooks, B.W., Foran, C.M., Richards, S.M., Weston, J., Turner, P.K., Stanley, J.K., Solomon, K.R., Slattery, M., and La Point, T.W. (2003) Aquatic ecotoxicology of fluoxetine. Toxicol. Lett. 142, 169-183.
17. Hirsch, R., Ternes, T., Haberer, K., and Kratz, K.-L. (1999) Occurrence of antibiotics in the aquatic environment. Sci. Total Environ. 225, 109-118.
18. Metcalfe, C.D., Miao, X.-S., Koenig, B.G., and Struger, J. (2003) Distribution of acidic and neutral drugs in surface waters near sewage treatment plants in the lower Great Lakes, Canada. Environ. Toxicol. Chem. 22, 2881-2889.
19. Miao, X.-S., Bishay, F., Chen, M., and Metcalfe, C.D. (2004). Occurrence of antimicrobials in the final effluents of wastewater treatment plants in Canada. Environ. Sci. Technol. 38, 3533-3541.
20. Miao, X.-S., Yang, J.-J., and Metcalfe, C.D. (2005). Fate of carbamazepine and its metabolites in a municipal wastewater treatment plant. Environ. Sci. Technol. 39, 7469-7475.
21. Kolpin, D.W., Skopec, M., Meyer, M.T., Furlong, E.T., and Zaugg, S.D. (2004) Urban contribution of pharmaceuticals and other organic wastewater contaminants to streams during differing flow conditions. Sci. Total Environ. 328, 119-130.
22. Heberer, T. (2002). Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. Toxicol. Lett. 131, 5-17.
23. Webb, S., Ternes, T., Gilbert, M., and Olejniczak, K. (2003) Indirect human exposure to pharmaceuticals via drinking water. Toxicol. Lett. 142, 157-167.
24. Jones, O.A.H., Voulvoulis, N., and Lester, J.N. (2005) Human pharmaceuticals in wastewater treatment processes. Crit. Rev. Environ. Sci. Technol. 35, 401-427.
25. Snyder, S.A., Westerhoff, P., Yoon, Y., and Sedlak, D.L. (2003). Pharmaceuticals, personal care products, and endocrine disruptors in water: implications for the water industry. Environ. Eng. Sci. 20, 449-469.
26. Joss, A., Zabcyzynski, S., Gobel, A., Hoffman, B., Loffler, D., McArdell, C.S., Ternes, T., Thomsen, A., and Siegrist, H. (2006) Biological degradation of pharmaceuticals in municipal wastewater treatment: proposing a classification scheme. Water Res. 40(8), 1686-1696.
27. Zwiener, C., Seeger, S., Glauner, T., and Frimmel, F.H. (2002) Metabolites from the biodegradation of pharmaceutical residues of ibuprofen in biofilm reactors and batch experiments. Anal. Bioanal. Chem. 372, 569-575.
28. Zwiener, C. and Frimmel, F.H. (2003) Short-term tests with a pilot sewage plan and biofilm reactors for the biological degradation of the pharmaceutical compounds clofibric acid, ibuprofen, and diclofenac. Sci. Total Environ. 309, 201-211.
29. Huber, M.M., Gõbel, A., Joss, A., Hermann, N., Lõffler, D., Mcardell, C.S., Ried, A., Siegrist, H., Ternes, T.A., and Gunten, U.V. (2005) Oxidation of pharmaceuticals during ozonation of municipal wastewater effluents: a pilot study. Environ. Sci. Technol. 39, 4290-4299.
30. 2 treatment of antiepileptic drug carbamazepiine. Chemosphere 54, 497-505.
31. Ternes, T.A., Meisenheimer, M., McDowell, D., Sacher, F., Brauch, H.-J., Haist-Gulde, B., Preuss, G., Wilme, U., and Zulei-Seibert, N. (2002) Removal of pharmaceuticals during drinking water treatment. Environ. Sci. Technol. 36, 3855-3863.
32. Heberer, T., Reddersen, K., and Mechilnski, A. (2002) From municipal sewage to drinking water: fate and removal of pharmaceutical residues in the aquatic environment in urban areas. Water Sci. Technol. 46, 81-88.
33. Kimura, K., Amy, G., Drewes, J.E., Heberer, T., Kim, T.-U., and Watanabe, Y. (2003) Rejection of organic micropollutants (disinfection by-products, endocrine disrupting compounds, and pharmaceutically active compounds) by NF/RO membranes. J. Membrane Sci. 227, 113-121.
34. Lin, A.Y.-C. and Reinhard, M. (2005) Photodegradation of the common environmental pharmaceuticals and estrogens in river water. Environ. Toxicol. Chem. 24, 1303-1309.
35. Scheytt, T., Mersmann, P., Lindstädt, R., and Herberer, T. (2005) Determination of sorption coefficients of pharmaceutically active substances carbamazepine, declofenac, and ibuprofen, in sandy sediments. Chemosphere 60, 245-253.
36. Stuer-Laurdisen, F., Birkved, M., Hansen, L.P., Holten,Lutzhoft, H.-C., and Halling-Sorenson, B. (2000) Environmental risk assessment of human pharmaceuticals in Denmark after normal therapeutic use. Chemosphere 40, 783-793.
37. D'Angelo, E.M. and Reddy, K.R. (2000) Aerobic and anaerobic transformations of pentachlorophenol in wetland soils. Soil Sci. Soc. Am. J. 64, 933-943.
38. Mulbah, C.K., Porterhouse, J.D., Jugsujinda, A., DeLaune, R.D., and Johnson, A.B. (2000) Impact of redox conditions on metolachlor and metribuzin degradation in Mississippi flood plain soils. J. Environ. Sci. Health B 35, 689-704.
39. DeLaune, R.D., Devai, I., Mulbah, C., Crozier, C., and Lindau, CW. (1997) The influence of soil redox conditions on atrazine degradation in wetlands. Agric. Ecosyst. Environ. 66, 41-46.
40. Andrews, D., Zhao, X., Huck, P., and, Metcalfe, C.D. (2006) Comparison of nitrification and denitrification for the removal of pharmaceuticals and personal care products from domestic wastewater, Water Res., submitted.
41. Buser, H.R., Poiger, T., and Muller, M.D. (1999) Occurrence and environmental behavior of the chiral pharmaceuticals drug ibuprofen in surface waters and in wastewater. Environ. Sci. Technol. 33, 2529-2535.
42. Andreozzi, R., Marotta, R., and Nichlas, P. (2003) Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment. Chemosphere 50, 1319-1330.
43. Brix, H. (1997) Do macrophytes play a role in constructed treatment wetlands? Water Sci. Technol. 35, 11-17.
44. White, J.R., Belmont, M.A., and Metcalfe, C.D. (2006) Loading of pharmaceuticals into a treatment wetland in Central Florida. J. Environ. Qual., in review.
45. Matamoros, V., Garcia, J., and Bayona, J.M. (2005) Behavior of selected pharmaceuticals in subsurface flow constructed wetlands: a pilot-scale study. Environ. Sci. Technol. 39, 5449-5454.
46. Wang, H., Jawitz, J.W., White, J.R., Martinez, C.J., and Sees, M.D. (2006) Rejuvenating the largest municipal treatment wetland in Florida. Ecol. Eng. 26, 132-146.