Structural and membrane binding analysis of the phox homology domain of phosphoinositide 3-kinase-C2α

Journal of Biological Chemistry

Volumn 281, Issue 51, 2006, Pages 39396-39406

  Stahelin, Robert V ^a   Karathanassis, Dimitrios ^b,d   Bruzik, Karol S ^a   Waterfield, Michael D ^c   Bravo, Jerónimo ^a,e   Williams, Roger L ^a   Cho, Wonhwa ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d Research Center for Biomaterials SA 15   (Greece)

^e Centro Nacional de Investigaciones Oncológicas   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE BINDING ANALYSIS; MONOLAYER TECHNIQUES; PHOSPHOINOSITIDES; PHOX HOMOLOGY (PX) DOMAINS;

CELL MEMBRANES; CRYSTAL STRUCTURE; ELECTROSTATICS; MONOLAYERS; MUTAGENESIS; SURFACE PLASMON RESONANCE;

ENZYMES;

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE C2 ALPHA; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; ENZYME BINDING; HYDROPHOBICITY; MEMBRANE BINDING; MONOLAYER CULTURE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; SURFACE PLASMON RESONANCE; X RAY CRYSTALLOGRAPHY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BINDING SITES; CELL MEMBRANE; ELECTROSTATICS; ESCHERICHIA COLI; HUMANS; KINETICS; LIPIDS; MODELS, MOLECULAR; MUTAGENESIS; PHOSPHATIDYLINOSITOLS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SURFACE PLASMON RESONANCE;

EID: 33846010781     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M607079200     Document Type: Article

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