A structure-function study of the C2 domain of cytosolic phospholipase A2: Identification of essential calcium ligands and hydrophobic membrane binding residues

Journal of Biological Chemistry

Volumn 274, Issue 14, 1999, Pages 9665-9672

  Bittova, Lenka ^a   Sumandea, Marius ^a   Cho, Wonhwa ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; LEUCINE; PHENYLALANINE; PHOSPHOLIPASE A2; PROTEIN KINASE C; TYROSINE; VALINE;

AMINO ACID COMPOSITION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CYTOSOL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; GENE MUTATION; LIGAND BINDING; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BACULOVIRIDAE; BINDING SITES; CALCIUM; COMPUTER SIMULATION; ESCHERICHIA COLI; KINETICS; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPASES A; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SPODOPTERA; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0033515664     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.14.9665     Document Type: Article

References (35)

1. Dennis, E. A. (1994) J. Biol. Chem. 269, 13057-13060
2. Murakami, M., Nakatani, Y., Atsumi, G., Inoue, K., and Kudo, I. (1997) Crit. Rev. Immunol. 17, 225-283
3. Leslie, C. C. (1997) J. Biol. Chem. 272, 16709-16712
4. Bonventre, J. V., Huang, Z., Taheri, M. R., O'Leary, E., Li, E., Moskowitz, M. A., and Sapirstein, A. (1997) Nature 390, 622-625
5. Uozumi, N., Kume, K., Nagase, T., Nakatani, N., Ishii, S., Tashiro, F., Komagata, Y., Maki, K., Ikuta, K., Ouchi, Y., Miyazaki, J., and Shimizu, T. (1997) Nature 390, 618-622
6. Glover, S., de Carvalho, M S , Bayburt, T., Jonas, M., Chi, E., Leslie, C. C., and Gelb, M. H. (1995) J. Biol. Chem. 270, 15359-15367
7. Schievella, A. R., Regier, M. K., Smith, W. L., and Lin, L. L. (1995) J. Biol. Chem. 270, 30749-30754
8. Clark, J. D., Lin, L. L., Kriz, R. W., Ramesha, C. S., Sultzman, L. A., Lin, A. Y., Milona, N., and Knopf, J. L. (1991) Cell 65, 1043-1051
9. Nalefski, E. A., Sultzman, L. A., Martin, D. M., Kriz, R. W., Towler, P. S., Knopf, J. L., and Clark, J. D. (1994) J. Biol. Chem. 269, 18239-18249
10. Medkova, M., and Cho, W. (1998) Biochemistry 37, 4892-4900
11. Sutton, R. B., and Sprang, S. R. (1998) Structure 6, 1395-1405
12. Perisic, O., Fong, S., Lynch, D. E., Bycroft, M., and Williams, R. L. (1998) J Biol. Chem. 273, 1596-1604
13. Xu, G. Y., McDonagh, T., Yu, H. A., Nalefski, E. A., Clark, J. D., and Cumming, D. A. (1998) J. Mol. Biol. 280, 485-500
14. Nalefski, E. A., and Falke, J. J. (1996) Protein Sci. 5, 2375-2390
15. Lichtenbergova, L., Yoon, E. T., and Cho, W. (1998) Biochemistry 37, 14128-14136
16. Davletov, B., Perisic, O., and Williams, R. L. (1998) J. Biol. Chem. 273, 19093-19096
17. Comfurius, P., and Zwaal, R. F. A. (1977) Biochim. Biophys. Acta 488, 36-42
18. Lands, W. E. (1960) J. Biol. Chem. 235, 2233-2237
19. Kim, Y., Lichtenbergova, L., Snitko, Y., and Cho, W. (1997) Anal. Biochem. 250, 109-116
20. Kates, M. (1986) in Techniques of Lipidology, 2nd Ed., pp. 114-115, Elsevier, Amsterdam
21. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst. ) 77, 51-9
22. Ghomashchi, F., Schuttel, S., Jain, M. K., and Gelb, M. H. (1992) Biochemistry 31, 3814-3824
23. Bers, D. M. (1982) Am. J. Physiol. 242, C404-C408
24. Nalefski, E. A., Slazas, M. M., and Falke, J. J. (1997) Biochemistry 36, 12011-12018
25. Rebecchi, M., Peterson, A., and McLaughlin, S. (1992) Biochemistry 31, 12742-12747
26. Verger, R., and Pattus, F. (1982) Chem. Phys. Lipids 30, 189-227
27. Mosior, M., Six, D. A., and Dennis, E. A. (1998) J. Biol. Chem. 273, 2184-2191
28. Nalefski, E. A., McDonagh, T., Somers, W., Seehra, J., Falke, J. J., and Clark, J. D. (1998) J. Biol. Chem. 273, 1365-1372
29. Medkova, M., and Cho, W. (1998) J. Biol. Chem. 273, 17544-17552
30. Dua, R., Wu, S.-K., and Cho, W. (1995) J. Biol. Chem. 270, 263-268
31. Han, S.-K., Yoon, E. T., Scott, D. L., Sigler, P. B., and Cho, W. (1997) J. Biol. Chem. 272, 3573-3582
32. Lee, B.-I., Yoon, E. T., and Cho, W. (1996) Biochemistry 35, 4231-4240
33. Snitko, Y., Koduri, R., Han, S.-K., Othman, R., Baker, S. F., Molini, B. J., Wilton, D. C., Gelb, M. H., and Cho, W. (1997) Biochemistry 36, 14325-14333
34. Chothia, C. (1974) Nature 248, 338-339
35. Yau, W. M., Wimley, W. C., Gawrisch, K., and White, S. H. (1998) Biochemistry 37, 14713-14718