Fowlicidin-3 is an α-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities

FEBS Journal

Volumn 274, Issue 2, 2007, Pages 418-428

  Bommineni, Yugendar R ^a   Dai, Huaien ^b   Gong, Yu Xi ^b   Soulages, Jose L ^a   Fernando, Samodha C ^a   DeSilva, Udaya ^a   Prakash, Om ^b   Zhang, Guolong ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

Author keywords

Antibiotic resistance; Antimicrobial peptide; Cathelicidin; Host defense; Structure activity relationship

Indexed keywords

ANTIINFECTIVE AGENT; CATHELICIDIN; FOWLICIDIN 3; LIPOPOLYSACCHARIDE; PEPTIDE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL STRAIN; CONCENTRATION (PARAMETERS); DRUG MECHANISM; DRUG PENETRATION; DRUG POTENCY; DRUG STRUCTURE; GENE EXPRESSION REGULATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HOST RESISTANCE; IMMUNOMODULATION; IN VITRO STUDY; MACROPHAGE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; SERUM; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BETA-DEFENSINS; CATIONS; DOGS; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, SECONDARY;

NEGIBACTERIA; POSIBACTERIA; VERTEBRATA;

EID: 33846006520     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2006.05589.x     Document Type: Article

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