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Volumn 555, Issue 2-3, 2007, Pages 164-173

Differential effects of dexamethasone, ondansetron and a tachykinin NK1 receptor antagonist (GR205171) on cisplatin-induced changes in behaviour, food intake, pica and gastric function in rats

Author keywords

Cisplatin; Dexamethasone; Fatigue; Gastric stasis; GR205171; Nausea; Ondansetron; Pica; Vomiting

Indexed keywords

CISPLATIN; DEXAMETHASONE; KAOLIN; ONDANSETRON; SEROTONIN 3 ANTAGONIST; TACHYKININ RECEPTOR ANTAGONIST; VOFOPITANT;

EID: 33845978333     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.10.043     Document Type: Article
Times cited : (67)

References (56)
  • 1
    • 0019865893 scopus 로고
    • High-dose dexamethasone for the prevention of cisplatin-induced vomiting
    • Aapro M.S., and Alberts D.S. High-dose dexamethasone for the prevention of cisplatin-induced vomiting. Cancer Chemother. Pharmacol. 7 (1981) 11-14
    • (1981) Cancer Chemother. Pharmacol. , vol.7 , pp. 11-14
    • Aapro, M.S.1    Alberts, D.S.2
  • 2
    • 0041464817 scopus 로고    scopus 로고
    • Assessment and management of cancer-related fatigue in adults
    • Ahlberg K., Ekman T., Gaston-Johansson F., and Mock V. Assessment and management of cancer-related fatigue in adults. Lancet 362 (2003) 40-650
    • (2003) Lancet , vol.362 , pp. 40-650
    • Ahlberg, K.1    Ekman, T.2    Gaston-Johansson, F.3    Mock, V.4
  • 3
    • 0012066129 scopus 로고    scopus 로고
    • Approaches to understanding the mechanisms involved in fatigue associated with cancer and its treatments: a speculative review
    • European School of Oncology Scientific Updates. Marty M., and Pecorelli S. (Eds), Elsevier
    • Andrews P.L.R., and Morrow G.R. Approaches to understanding the mechanisms involved in fatigue associated with cancer and its treatments: a speculative review. In: Marty M., and Pecorelli S. (Eds). European School of Oncology Scientific Updates. Fatigue and Cancer vol. 5 (2002), Elsevier 1-15
    • (2002) Fatigue and Cancer , vol.5 , pp. 1-15
    • Andrews, P.L.R.1    Morrow, G.R.2
  • 6
    • 0015188413 scopus 로고
    • Differential effects of dexamethasone and body weight loss on two measures of activity
    • Beattie W.W., Scoutenm C.W., and Beattie P.A. Differential effects of dexamethasone and body weight loss on two measures of activity. Physiol. Behav. 7 (1971) 869-871
    • (1971) Physiol. Behav. , vol.7 , pp. 869-871
    • Beattie, W.W.1    Scoutenm, C.W.2    Beattie, P.A.3
  • 7
    • 0018818381 scopus 로고
    • cis-platinum (II) amine complexes: some structure activity relationships for immunosuppressive, nephrotoxic and gastrointestinal (side) effects in rats
    • Broomhead J.A., Fairlie D.P., and Whitehouse M.W. cis-platinum (II) amine complexes: some structure activity relationships for immunosuppressive, nephrotoxic and gastrointestinal (side) effects in rats. Chem. Biol. Interact. 31 (1980) 113-132
    • (1980) Chem. Biol. Interact. , vol.31 , pp. 113-132
    • Broomhead, J.A.1    Fairlie, D.P.2    Whitehouse, M.W.3
  • 8
    • 0019954273 scopus 로고
    • Dexamethasone: a potent blocker for radiation-induced taste aversion in rats
    • Cairnie A.B., and Leach K.E. Dexamethasone: a potent blocker for radiation-induced taste aversion in rats. Pharmacol. Biochem. Behav. 17 (1982) 305-311
    • (1982) Pharmacol. Biochem. Behav. , vol.17 , pp. 305-311
    • Cairnie, A.B.1    Leach, K.E.2
  • 10
    • 0010520901 scopus 로고
    • 5-HT3 antagonists reverse the cisplatin induced slowing of gastric emptying in fed rats
    • Eeckhout C., and Vedder A. 5-HT3 antagonists reverse the cisplatin induced slowing of gastric emptying in fed rats. Gastroenterology 94 (1988) A111
    • (1988) Gastroenterology , vol.94
    • Eeckhout, C.1    Vedder, A.2
  • 11
    • 33845982632 scopus 로고
    • Capsaicin-sensitive vagal afferent pathways mediate the effects of cisplatin on gastric emptying in the rat
    • Eeckhout C. Capsaicin-sensitive vagal afferent pathways mediate the effects of cisplatin on gastric emptying in the rat. J. Gastrointest. Motil. 1 (1989) A52
    • (1989) J. Gastrointest. Motil. , vol.1
    • Eeckhout, C.1
  • 12
    • 33845982632 scopus 로고
    • Effects of prokinetics with a different mechanism of action on cislatin-induced slowing of gastric emptying in the rat
    • Eeckhout C. Effects of prokinetics with a different mechanism of action on cislatin-induced slowing of gastric emptying in the rat. J. Gastrointest. Motil. 1 (1989) A52
    • (1989) J. Gastrointest. Motil. , vol.1
    • Eeckhout, C.1
  • 13
    • 0036150908 scopus 로고    scopus 로고
    • PRL-releasing peptide interacts with leptin to reduce food intake and body weight
    • Ellacott K.L.J., Lawrence C.B., Rothwell N.J., and Luckman S.M. PRL-releasing peptide interacts with leptin to reduce food intake and body weight. Endocrinology 143 (2002) 368-374
    • (2002) Endocrinology , vol.143 , pp. 368-374
    • Ellacott, K.L.J.1    Lawrence, C.B.2    Rothwell, N.J.3    Luckman, S.M.4
  • 14
    • 0025602451 scopus 로고
    • The effect of ondansetron on gastric emptying in the conscious rat
    • Forster E.R., and Dockray G.J. The effect of ondansetron on gastric emptying in the conscious rat. Eur. J. Pharmacol. 191 (1990) 235-238
    • (1990) Eur. J. Pharmacol. , vol.191 , pp. 235-238
    • Forster, E.R.1    Dockray, G.J.2
  • 15
    • 0032213962 scopus 로고    scopus 로고
    • Effects of granisetron and its combination with dexamethasone on cisplatin-induced delayed emesis in the ferret
    • Fukunaka N., Sagae S., Kudo R., Endo T., Hirafuji M., and Minami M. Effects of granisetron and its combination with dexamethasone on cisplatin-induced delayed emesis in the ferret. Gen. Pharmacol. 31 (1998) 775-781
    • (1998) Gen. Pharmacol. , vol.31 , pp. 775-781
    • Fukunaka, N.1    Sagae, S.2    Kudo, R.3    Endo, T.4    Hirafuji, M.5    Minami, M.6
  • 17
    • 0030603866 scopus 로고    scopus 로고
    • GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity
    • Gardner C.J., Armour D.R., Beattie D.T., Gale J.D., Hawcock A.B., Kilpatrick G.J., Twissell D.J., and Ward P. GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity. Regul. Pept. 65 (1996) 45-53
    • (1996) Regul. Pept. , vol.65 , pp. 45-53
    • Gardner, C.J.1    Armour, D.R.2    Beattie, D.T.3    Gale, J.D.4    Hawcock, A.B.5    Kilpatrick, G.J.6    Twissell, D.J.7    Ward, P.8
  • 18
    • 0028227671 scopus 로고
    • Consistency of meal patterns in laboratory rats
    • Glendinning J.I., and Smith J.C. Consistency of meal patterns in laboratory rats. Physiol. Behav. 56 (1994) 7-16
    • (1994) Physiol. Behav. , vol.56 , pp. 7-16
    • Glendinning, J.I.1    Smith, J.C.2
  • 19
    • 0027076148 scopus 로고
    • Single dose ondansetron for the prevention of cisplatin-induced emesis: efficacy results
    • Hainsworth J.D., and Hesketh P.J. Single dose ondansetron for the prevention of cisplatin-induced emesis: efficacy results. Semin. Oncol. 19 (1992) 14-19
    • (1992) Semin. Oncol. , vol.19 , pp. 14-19
    • Hainsworth, J.D.1    Hesketh, P.J.2
  • 20
    • 0025129323 scopus 로고
    • Dexamethasone can potentiate the anti-emetic action of a 5HT3 receptor antagonist on cyclophosphamide induced vomiting in the ferret
    • Hawthorn J., and Cunningham D. Dexamethasone can potentiate the anti-emetic action of a 5HT3 receptor antagonist on cyclophosphamide induced vomiting in the ferret. Br. J. Cancer. 61 (1990) 56-60
    • (1990) Br. J. Cancer. , vol.61 , pp. 56-60
    • Hawthorn, J.1    Cunningham, D.2
  • 21
    • 0038185163 scopus 로고    scopus 로고
    • Differential involvement of neurotransmitters through the time course of cisplatin-induced emesis as revealed by therapy with specific receptor antagonists
    • Hesketh P.J., Van Belle S., Aapro M., Tattersall F.D., Naylor R.J., Hargreaves R., Carides A.D., Evans J.K., and Horgan K.J. Differential involvement of neurotransmitters through the time course of cisplatin-induced emesis as revealed by therapy with specific receptor antagonists. Eur. J. Cancer 39 (2003) 1074-1080
    • (2003) Eur. J. Cancer , vol.39 , pp. 1074-1080
    • Hesketh, P.J.1    Van Belle, S.2    Aapro, M.3    Tattersall, F.D.4    Naylor, R.J.5    Hargreaves, R.6    Carides, A.D.7    Evans, J.K.8    Horgan, K.J.9
  • 22
    • 33845993665 scopus 로고    scopus 로고
    • In vivo imaging of tachykinin NK1 receptor agonist induced reflux in rats
    • Hultin L., Hyberg G., Lindsrom E., and Lehmann A. In vivo imaging of tachykinin NK1 receptor agonist induced reflux in rats. Neorogastroenterol. Motil. 17 Suppl. 2 (2005) 60
    • (2005) Neorogastroenterol. Motil. , vol.17 , Issue.SUPPL. 2 , pp. 60
    • Hultin, L.1    Hyberg, G.2    Lindsrom, E.3    Lehmann, A.4
  • 23
    • 0029658428 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine3 receptor and regulation of gastric emptying in rats
    • Ito C., Isobe Y., Tsuchida K., and Higuchi S. 5-Hydroxytryptamine3 receptor and regulation of gastric emptying in rats. Arch. Int. Pharmacodyn. Ther. 331 (1996) 203-218
    • (1996) Arch. Int. Pharmacodyn. Ther. , vol.331 , pp. 203-218
    • Ito, C.1    Isobe, Y.2    Tsuchida, K.3    Higuchi, S.4
  • 24
    • 0031024843 scopus 로고    scopus 로고
    • Cisplatin-induced inhibition of the calcium-calmodulin complex, neuronal nitric oxide synthase activation and their role in stomach distension
    • Jarve R.K., and Aggarwal S.K. Cisplatin-induced inhibition of the calcium-calmodulin complex, neuronal nitric oxide synthase activation and their role in stomach distension. Cancer Chemother. Pharmacol. 39 (1997) 341-348
    • (1997) Cancer Chemother. Pharmacol. , vol.39 , pp. 341-348
    • Jarve, R.K.1    Aggarwal, S.K.2
  • 25
    • 0036498510 scopus 로고    scopus 로고
    • Cytokine-induced sickness behaviour: mechanisms and implications
    • Konsman J.P., Parnet P., and Dantzer R. Cytokine-induced sickness behaviour: mechanisms and implications. Trends Neurosci. 25 (2002) 154-159
    • (2002) Trends Neurosci. , vol.25 , pp. 154-159
    • Konsman, J.P.1    Parnet, P.2    Dantzer, R.3
  • 26
    • 1642565342 scopus 로고    scopus 로고
    • Additive effects of leptin and topiramate in reducing fat deposition in lean and obese ob/ob mice
    • Lalonde J., Samson P., Poulin S., Deshaies Y., and Richard D. Additive effects of leptin and topiramate in reducing fat deposition in lean and obese ob/ob mice. Physiol. Behav. 80 (2004) 415-420
    • (2004) Physiol. Behav. , vol.80 , pp. 415-420
    • Lalonde, J.1    Samson, P.2    Poulin, S.3    Deshaies, Y.4    Richard, D.5
  • 29
    • 33644922916 scopus 로고    scopus 로고
    • Behavioural and molecular effects of the anti-cancer agent cisplatin in the rat: a model of chemotherapy-related malaise
    • Malik N.M., Moore G.B.T., Smith G., Liu Y.-L., Sanger G.J., and Andrews P.L.R. Behavioural and molecular effects of the anti-cancer agent cisplatin in the rat: a model of chemotherapy-related malaise. Pharmacol. Biochem. Behav. 83 (2006) 9-20
    • (2006) Pharmacol. Biochem. Behav. , vol.83 , pp. 9-20
    • Malik, N.M.1    Moore, G.B.T.2    Smith, G.3    Liu, Y.-L.4    Sanger, G.J.5    Andrews, P.L.R.6
  • 30
    • 0029789099 scopus 로고    scopus 로고
    • The severity and pattern of emesis following different cytotoxic agents
    • Martin M. The severity and pattern of emesis following different cytotoxic agents. Oncology 53 (1996) 26-31
    • (1996) Oncology , vol.53 , pp. 26-31
    • Martin, M.1
  • 31
    • 0032563181 scopus 로고    scopus 로고
    • GR205171 blocks apomorphine and amphetamine-induced conditioned taste aversions
    • McAllister K.H., and Pratt J.A. GR205171 blocks apomorphine and amphetamine-induced conditioned taste aversions. Eur. J. Pharmacol. 353 (1998) 141-148
    • (1998) Eur. J. Pharmacol. , vol.353 , pp. 141-148
    • McAllister, K.H.1    Pratt, J.A.2
  • 32
    • 0026780914 scopus 로고
    • Cisplatin-induced conditioned taste aversion: attenuation by dexamethasone but not zacopride or GR38032F
    • Mele P.C., McDonough J.R., McLean D.B., and O'Halloran K.P. Cisplatin-induced conditioned taste aversion: attenuation by dexamethasone but not zacopride or GR38032F. Eur. J. Pharmacol. 218 (1992) 229-236
    • (1992) Eur. J. Pharmacol. , vol.218 , pp. 229-236
    • Mele, P.C.1    McDonough, J.R.2    McLean, D.B.3    O'Halloran, K.P.4
  • 33
    • 28744447327 scopus 로고    scopus 로고
    • Increased ghrelin receptor mRNA and therapeutic effects of ghrelin after acute cisplatin treatment
    • Moore G.B.T., Malik N., Liu R.W., and Corcoron G.L. Increased ghrelin receptor mRNA and therapeutic effects of ghrelin after acute cisplatin treatment. Neurogastroenterol. Motil. 15 (2003) A12
    • (2003) Neurogastroenterol. Motil. , vol.15
    • Moore, G.B.T.1    Malik, N.2    Liu, R.W.3    Corcoron, G.L.4
  • 34
    • 1542543332 scopus 로고    scopus 로고
    • Differential effects of paroxetine on fatigue and depression: a randomized, double blind trial from the University of Rochester Cancer Centre Community Oncology Program
    • Morrow G.R., Hickok J.T., Roscoe J.A., Raubertas R.F., Andrews P.L.R., Flynn P.J., Hynes H.E., Banerjee T.K., Kirshner J.J., and King D.K. Differential effects of paroxetine on fatigue and depression: a randomized, double blind trial from the University of Rochester Cancer Centre Community Oncology Program. J. Clin. Oncol. 21 (2003) 4635-4641
    • (2003) J. Clin. Oncol. , vol.21 , pp. 4635-4641
    • Morrow, G.R.1    Hickok, J.T.2    Roscoe, J.A.3    Raubertas, R.F.4    Andrews, P.L.R.5    Flynn, P.J.6    Hynes, H.E.7    Banerjee, T.K.8    Kirshner, J.J.9    King, D.K.10
  • 36
    • 0036940618 scopus 로고    scopus 로고
    • Cancer and chemotherapy-related upper gastrointestinal symptoms: the role of abnormal gastric motor function and its evaluation in cancer patients
    • Nelson K., Walsh D., and Sheehan F. Cancer and chemotherapy-related upper gastrointestinal symptoms: the role of abnormal gastric motor function and its evaluation in cancer patients. Support. Care Cancer 10 (2002) 455-461
    • (2002) Support. Care Cancer , vol.10 , pp. 455-461
    • Nelson, K.1    Walsh, D.2    Sheehan, F.3
  • 38
    • 0023784288 scopus 로고
    • Glucocorticoids attenuate taste aversions produced by toxins in rats
    • Revusky S., and Martin G.M. Glucocorticoids attenuate taste aversions produced by toxins in rats. Psychopharmacology (Berl) 96 (1988) 400-407
    • (1988) Psychopharmacology (Berl) , vol.96 , pp. 400-407
    • Revusky, S.1    Martin, G.M.2
  • 39
    • 0019468491 scopus 로고
    • A peculiar toxicity manifested by platinum (II) amines in rats: gastric distension after intraperitoneal administration
    • Roos I.A., Fairlie D.P., and Whitehouse M.W. A peculiar toxicity manifested by platinum (II) amines in rats: gastric distension after intraperitoneal administration. Chem. Biol. Interact. 35 (1981) 111-117
    • (1981) Chem. Biol. Interact. , vol.35 , pp. 111-117
    • Roos, I.A.1    Fairlie, D.P.2    Whitehouse, M.W.3
  • 40
    • 0036933004 scopus 로고    scopus 로고
    • Temporal interrelationships among fatigue, circadian rhythm and depression in breast cancer patients undergoing chemotherapy treatment
    • Roscoe J.A., Morrow G.R., Hickok J.T., Bushunow P., Matteson S., Rakita D., and Andrews P.L.R. Temporal interrelationships among fatigue, circadian rhythm and depression in breast cancer patients undergoing chemotherapy treatment. Support. Care Cancer 10 (2002) 329-336
    • (2002) Support. Care Cancer , vol.10 , pp. 329-336
    • Roscoe, J.A.1    Morrow, G.R.2    Hickok, J.T.3    Bushunow, P.4    Matteson, S.5    Rakita, D.6    Andrews, P.L.R.7
  • 42
    • 0029944390 scopus 로고    scopus 로고
    • An interaction of ondansetron and dexamethasone antagonizing cisplatin-induced acute and delayed emesis in the ferret
    • Rudd J.A., and Naylor R.J. An interaction of ondansetron and dexamethasone antagonizing cisplatin-induced acute and delayed emesis in the ferret. Br. J. Pharmacol. 118 (1996) 209-214
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 209-214
    • Rudd, J.A.1    Naylor, R.J.2
  • 43
    • 0029658238 scopus 로고    scopus 로고
    • The action of the NK1 tachykinin receptor antagonist, CP 99,994, in antagonizing the acute and delayed emesis induced by cisplatin in the ferret
    • Rudd J.A., Jordan C.C., and Naylor R.J. The action of the NK1 tachykinin receptor antagonist, CP 99,994, in antagonizing the acute and delayed emesis induced by cisplatin in the ferret. Br. J. Pharmacol. 119 (1996) 931-936
    • (1996) Br. J. Pharmacol. , vol.119 , pp. 931-936
    • Rudd, J.A.1    Jordan, C.C.2    Naylor, R.J.3
  • 44
    • 0031594881 scopus 로고    scopus 로고
    • 5-HT3 receptors are not involved in conditioned taste aversions induced by 5-hydroxytryptamine, ipecacuanha or cisplatin
    • Rudd J.A., Ngan M.P., and Wai M.K. 5-HT3 receptors are not involved in conditioned taste aversions induced by 5-hydroxytryptamine, ipecacuanha or cisplatin. Eur. J. Pharmacol. 352 (1998) 143-149
    • (1998) Eur. J. Pharmacol. , vol.352 , pp. 143-149
    • Rudd, J.A.1    Ngan, M.P.2    Wai, M.K.3
  • 45
    • 0036843712 scopus 로고    scopus 로고
    • Differential action of ondansetron and dexamethasone to modify cisplatin-induced acute and delayed kaolin consumption ("pica") in rats
    • Rudd J.A., Yamamoto K., Yamatodani A., and Takeda N. Differential action of ondansetron and dexamethasone to modify cisplatin-induced acute and delayed kaolin consumption ("pica") in rats. Eur. J. Pharmacol. 454 (2002) 47-52
    • (2002) Eur. J. Pharmacol. , vol.454 , pp. 47-52
    • Rudd, J.A.1    Yamamoto, K.2    Yamatodani, A.3    Takeda, N.4
  • 46
    • 0034904449 scopus 로고    scopus 로고
    • Effects of HSP-117, a novel tachykinin NK1-receptor antagonist, on cisplatin-induced pica as a new evaluation of delayed emesis in rats
    • Saeki M., Sakai M., Saito R., Kubota H., Ariumi H., Takano Y., Yamatodani A., and Kamiya H. Effects of HSP-117, a novel tachykinin NK1-receptor antagonist, on cisplatin-induced pica as a new evaluation of delayed emesis in rats. Jpn. J. Pharmacol. 86 (2001) 359-362
    • (2001) Jpn. J. Pharmacol. , vol.86 , pp. 359-362
    • Saeki, M.1    Sakai, M.2    Saito, R.3    Kubota, H.4    Ariumi, H.5    Takano, Y.6    Yamatodani, A.7    Kamiya, H.8
  • 47
    • 2442476519 scopus 로고    scopus 로고
    • Neurokin NK1 and NK3 receptors as targets for drugs to treat gastrointestinal motility disorders and pain
    • Sanger G.J. Neurokin NK1 and NK3 receptors as targets for drugs to treat gastrointestinal motility disorders and pain. Br. J. Pharmacol. 141 (2004) 1-10
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 1-10
    • Sanger, G.J.1
  • 48
    • 0032146705 scopus 로고    scopus 로고
    • Reversal of cisplatin-induced delay in gastric emptying in rats by ginger (Zingiber officinale)
    • Sharma S.S., and Gupta Y.K. Reversal of cisplatin-induced delay in gastric emptying in rats by ginger (Zingiber officinale). J. Ethnopharmacol. 62 (1998) 49-55
    • (1998) J. Ethnopharmacol. , vol.62 , pp. 49-55
    • Sharma, S.S.1    Gupta, Y.K.2
  • 49
    • 0032190136 scopus 로고    scopus 로고
    • Fatigue in patients with cancer
    • Stone P., Richards M., and Hardy J. Fatigue in patients with cancer. Eur. J. Cancer 34 (1998) 1670-1676
    • (1998) Eur. J. Cancer , vol.34 , pp. 1670-1676
    • Stone, P.1    Richards, M.2    Hardy, J.3
  • 51
    • 0033807848 scopus 로고    scopus 로고
    • Cancer-related fatigue: inevitable, unimportant and untreatable? Results of a multi-centre patient survey
    • Stone P., Richardson A., Ream E., Smith A.G., Kerr D.J., and Kearney N. Cancer-related fatigue: inevitable, unimportant and untreatable? Results of a multi-centre patient survey. Cancer Fatigue Forum. Ann. Oncol.11 (2000) 971-975
    • (2000) Cancer Fatigue Forum. Ann. , vol.Oncol.11 , pp. 971-975
    • Stone, P.1    Richardson, A.2    Ream, E.3    Smith, A.G.4    Kerr, D.J.5    Kearney, N.6
  • 52
  • 54
    • 12244284671 scopus 로고    scopus 로고
    • Antiemetic effect of a tachykinin NK1 receptor antagonist GR205171 on cisplatin-induced early and delayed emesis in the pigeon
    • Tanihata S., Oda S., Kakuta S., and Uchiyama T. Antiemetic effect of a tachykinin NK1 receptor antagonist GR205171 on cisplatin-induced early and delayed emesis in the pigeon. Eur. J. Pharmacol. 461 (2003) 197-206
    • (2003) Eur. J. Pharmacol. , vol.461 , pp. 197-206
    • Tanihata, S.1    Oda, S.2    Kakuta, S.3    Uchiyama, T.4
  • 55
    • 0030700785 scopus 로고    scopus 로고
    • Effects of cisplatin and taxol on inducible nitric oxide synthase, gastrin and somatostatin in gastrointestinal toxicity
    • Wang Y., and Aggarwal S.K. Effects of cisplatin and taxol on inducible nitric oxide synthase, gastrin and somatostatin in gastrointestinal toxicity. Anticancer Drugs 8 (1997) 853-858
    • (1997) Anticancer Drugs , vol.8 , pp. 853-858
    • Wang, Y.1    Aggarwal, S.K.2
  • 56
    • 0030733486 scopus 로고    scopus 로고
    • Participation of a cholinergic mechanism in 5-hydroxytryptamine (5-HT)3 and 5-HT4 receptor-mediated stimulation of gastric emptying in rats
    • Yamano M., Kamato T., and Miyata K. Participation of a cholinergic mechanism in 5-hydroxytryptamine (5-HT)3 and 5-HT4 receptor-mediated stimulation of gastric emptying in rats. Arzneimittelforschung 47 (1997) 1242-1246
    • (1997) Arzneimittelforschung , vol.47 , pp. 1242-1246
    • Yamano, M.1    Kamato, T.2    Miyata, K.3


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