Participation of a cholinergic mechanism in 5-hydroxytryptamine (5-HT)3 and 5-HT4 receptor-mediated stimulation of gastric emptying in rats

Arzneimittel-Forschung/Drug Research

Volumn 47, Issue 11, 1997, Pages 1242-1246

  Yamano, Mayumi ^a   Kamato, Takeshi ^a   Miyata, Keiji ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

5 Hydroxytryptamine, 5 HT3 and 5 HT4 receptors; Benzamides, gastroprokinetic effects; CAS 132038 88 5; Gastric emptying; Ramosetron; YM060

Indexed keywords

1 METHYL 3 INDOLECARBOXYLIC ACID [1 [2 (METHYLSULFONYLAMINO)ETHYL] 4 PIPERIDINYLMETHYL] ESTER; 5 METHOXYTRYPTAMINE; ATROPINE; BENZAMIDE DERIVATIVE; CISAPRIDE; ONDANSETRON; RAMOSETRON; SEROTONIN ANTAGONIST; TETRODOTOXIN; TROPISETRON; ZACOPRIDE;

ANIMAL EXPERIMENT; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; RAT; STOMACH EMPTYING; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; ATROPINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTRIC EMPTYING; MALE; MUSCARINIC ANTAGONISTS; PARASYMPATHETIC NERVOUS SYSTEM; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; TETRODOTOXIN;

EID: 0030733486     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Costall, B., Gunning, S. J., Naylor, R. J., Neuropharmacology 24, 869 (1985)
2. Schiavone A., Volonte, M., Micheletti, R.; Eur. J. Pharmacol. 187, 323 (1990)
3. Gullikson, G. W. Virina, M. A., Loeffler, R. F. et al., Drug Dev. Res. 26, 405 (1992)
4. Ku, P., Wong, A. G., Perry, M. R., Pharmacologist 35, 191 (1993)
5. Dumuis, A., Sebben, M., Bockaert, J., Eur. J. Pharmacol. 162, 381 (1989)
6. Dumuis, A., Sebben, M., Bockaert, J., Naunyn-Schmiedeberg's Arch. Pharmacol. 340, 403 (1989)
7. Schiantarelli, P., Bockaert, J. Cesana, R. et al., Pharmacol. Res. 22, 453 (1990)
8. Linnik, M. D., Butler, B. T., Gaddis, R. R. et al., J. Pharmacol. Exp. Ther. 259, 501 (1991)
9. Gullikson, G. W., Virina, M. A., Loeffler, R. F. et al., J. Pharmacol. Exp. Ther. 264, 240 (1993)
10. Rizzi, C. A., Sagrada, A., Schiavone, A. et al., Naunyn-Schmiedeberg's Arch. Pharmacol. 349, 338 (1994)
11. Hegde, S. S., Wong, A. G., Perry, M. R. et al., Naunyn-Schmiedeberg's Arch. Pharmacol. 351, 589 (1995)
12. Costall, B., Gunning, S. J., Naylor, R. J. et al., Br. J. Pharmacol. 91, 263 (1987)
13. Turconi, M., Donetti, A., Schiavone, A. et al., Eur. J. Pharmacol. 203, 203 (1991)
14. Haga, K., Asano, K., Inaba, K. et al., Arch. Int. Pharmacodyn. Ther. 328, 344 (1994)
15. Burke, T. A., Sanger, G. J., Br. J. Clin. Pharmacol. 26, 261 (1988)
16. Rizzi, C. A., Coccini, T., Onori, L. et al., J. Pharmacol. Exp. Ther. 261, 412 (1992)
17. Dhasmana, K. M., Zhu, Y. N., Cruz, S. L. et al., Life Sci. 53, 1651 (1993)
18. Matsuyama, S., Sakiyama, H., Nei, K. et al., Jpn. J. Pharmacol. 64, 90P (1994)
19. Kilbinger, H., Gebauer, A., Haas, J. et al., Naunyn-Schmiedeberg's Arch. Pharmacol. 351, 229 (1995)
20. Miyata, K., Yamano, M., Kamato, T. et al., Jpn. J. Pharmacol. 69, 205 (1995)
21. Miyata, K., Kamato, T., Nishida, A. et al., J. Pharmacol. Exp. Ther. 259, 15 (1991)
22. Ito, H., Akuzawa, S., Tsutsumi, R. et al., Neuropharmacology 34, 631 (1995)
23. Talley, N. J., Aliment, Pharmacol. Ther. 6, 273 (1992)
24. Hodge, C. W., Neiehus, J. S., Samson, H. H., Psychopharmacology-Berl 119, 186 (1995)
25. Barnes, J. M., Barnes, N. M., Costall, B. et al., Nature 338, 762 (1989)
26. Miyata, K., Kamato, T. Nishida, A. et al., J. Pharmacol. Exp. Ther. 261, 297 (1992)
27. Moran, A., Velasco, C., Martin, M. L. et al., Eur. J. Pharmacol. 252, 161 (1994)
28. Yamano, M., Ito, H., Kamato, T. et al., Arch. Int. Pharmacodyn. Ther. 330, 177 (1995)
29. Consolo, S., Arnaboldi, S., Giorgi, S. et al., Neuroreport 5, 1230 (1994)