Behavioural and hypothalamic molecular effects of the anti-cancer agent cisplatin in the rat: A model of chemotherapy-related malaise?

Pharmacology Biochemistry and Behavior

Volumn 83, Issue 1, 2006, Pages 9-20

  Malik, N M ^a   Moore, G B T ^b   Smith, G ^a   Liu, Y L ^a   Sanger, G J ^b   Andrews, P L R ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Agouti related peptide; Cisplatin; CRF; Emesis; Food intake; Gastric stasis; IL 1; IL 6; Illness behaviour; Malaise; Nausea; Neuropeptide Y; Orexin; Serotonin transporter; Tryptophan hydroxylase; Tryptophan transporter; Tumour necrosis factor

Indexed keywords

ABC TRANSPORTER A1; ANTINEOPLASTIC AGENT; CISPLATIN; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INTERLEUKIN 1; INTERLEUKIN 6; MESSENGER RNA; NEUROPEPTIDE Y; OREXIN; SODIUM CHLORIDE; TRYPTOPHAN HYDROXYLASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; FLUID INTAKE; FOOD INTAKE; LOCOMOTION; MALAISE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; STOMACH CONTENT;

ANIMALS; ANTINEOPLASTIC AGENTS; BEHAVIOR, ANIMAL; BODY WEIGHT; CISPLATIN; DISEASE MODELS, ANIMAL; DRINKING; EATING; GASTROINTESTINAL CONTENTS; HYPOTHALAMUS; MALE; MOTOR ACTIVITY; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

AGOUTI; ANIMALIA;

EID: 33644922916     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2005.11.017     Document Type: Article

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