-
1
-
-
0033054725
-
Effects of weight loss on regional fat distribution and insulin sensitivity in obesity
-
Goodpaster BH, Kelley DE, Wing RR, Meier A, Thaete FL (1999) Effects of weight loss on regional fat distribution and insulin sensitivity in obesity. Diabetes 48:839-847
-
(1999)
Diabetes
, vol.48
, pp. 839-847
-
-
Goodpaster, B.H.1
Kelley, D.E.2
Wing, R.R.3
Meier, A.4
Thaete, F.L.5
-
2
-
-
4143060180
-
Intramyocellular lipid content in type 2 diabetes patients compared to overweight sedentary men and highly trained endurance athletes
-
van Loon LJC, Koopman R, Manders R, van der Weegen W, van Kranenburg GP, Keizer HA (2004) Intramyocellular lipid content in type 2 diabetes patients compared to overweight sedentary men and highly trained endurance athletes. Am J Physiol Endocrinol Metab 287:E558-EE565
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
van Loon, L.J.C.1
Koopman, R.2
Manders, R.3
van der Weegen, W.4
van Kranenburg, G.P.5
Keizer, H.A.6
-
3
-
-
0038697895
-
Intramyocellular lipids: Anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity
-
Thamer C, Machann J, Bachmann O et al (2003) Intramyocellular lipids: anthropometric determinants and relationships with maximal aerobic capacity and insulin sensitivity. J Clin Endocrinol Metab 88:1785-1791
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 1785-1791
-
-
Thamer, C.1
Machann, J.2
Bachmann, O.3
-
4
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
Yu C, Chen Y, Cline GW et al (2002) Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 277:50230-50236
-
(2002)
J Biol Chem
, vol.277
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
-
5
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI (2000) Cellular mechanisms of insulin resistance. J Clin Invest 106:171-176
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
6
-
-
0029948212
-
Mechanism of free fatty acid-induced insulin resistance
-
Roden M, Price TB, Perseghin G et al (1996) Mechanism of free fatty acid-induced insulin resistance. J Clin Invest 97:2859-2865
-
(1996)
J Clin Invest
, vol.97
, pp. 2859-2865
-
-
Roden, M.1
Price, T.B.2
Perseghin, G.3
-
7
-
-
0142070953
-
Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: A case of good vs. bad lipids?
-
Russell AP, Gastaldi G, Bobbioni-Harsch E et al (2003) Lipid peroxidation in skeletal muscle of obese as compared to endurance-trained humans: a case of good vs. bad lipids? FEBS Lett 551:104-106
-
(2003)
FEBS Lett
, vol.551
, pp. 104-106
-
-
Russell, A.P.1
Gastaldi, G.2
Bobbioni-Harsch, E.3
-
8
-
-
0346729968
-
Ceramide content is increased in skeletal muscle from obese insulin-resistant humans
-
Adams II JM, Pratipanawatr T, Berria R et al (2004) Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. Diabetes 53:25-31
-
(2004)
Diabetes
, vol.53
, pp. 25-31
-
-
Adams II, J.M.1
Pratipanawatr, T.2
Berria, R.3
-
9
-
-
0033834079
-
Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle
-
Ellis BA, Poynten A, Lowy AJ et al (2000) Long-chain acyl-CoA esters as indicators of lipid metabolism and insulin sensitivity in rat and human muscle. Am J Physiol Endocrinol Metab 279:E554-E560
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Ellis, B.A.1
Poynten, A.2
Lowy, A.J.3
-
10
-
-
0036300538
-
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
-
Itani SI, Ruderman NB, Schmieder F, Boden G (2002) Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes 51:2005-2011
-
(2002)
Diabetes
, vol.51
, pp. 2005-2011
-
-
Itani, S.I.1
Ruderman, N.B.2
Schmieder, F.3
Boden, G.4
-
11
-
-
0033856104
-
Plasma FFA utilization and fatty acid-binding protein content are diminished in type 2 diabetic muscle
-
Blaak EE, Wagenmakers AJM, Glatz JFC et al (2000) Plasma FFA utilization and fatty acid-binding protein content are diminished in type 2 diabetic muscle. Am J Physiol Endocrinol Metab 279:E146-E154
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Blaak, E.E.1
Wagenmakers, A.J.M.2
Glatz, J.F.C.3
-
12
-
-
0023618126
-
Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes
-
Felber JP, Ferrannini E, Golay A et al (1987) Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes. Diabetes 36:1341-1350
-
(1987)
Diabetes
, vol.36
, pp. 1341-1350
-
-
Felber, J.P.1
Ferrannini, E.2
Golay, A.3
-
13
-
-
0021329259
-
Study on lipid metabolism in obesity diabetes
-
Golay A, Felber JP, Meyer HU, Curchod B, Maeder E, Jequier E (1984) Study on lipid metabolism in obesity diabetes. Metabolism 33:111-116
-
(1984)
Metabolism
, vol.33
, pp. 111-116
-
-
Golay, A.1
Felber, J.P.2
Meyer, H.U.3
Curchod, B.4
Maeder, E.5
Jequier, E.6
-
14
-
-
0027946529
-
Impaired free fatty acid utilization by skeletal muscle in non-insulin dependent diabetes mellitus
-
Kelley DE, Simoneau J-A (1994) Impaired free fatty acid utilization by skeletal muscle in non-insulin dependent diabetes mellitus. J Clin Invest 94:2349-2356
-
(1994)
J Clin Invest
, vol.94
, pp. 2349-2356
-
-
Kelley, D.E.1
Simoneau, J.-A.2
-
15
-
-
0032900540
-
Substrate utilization and glucose turnover during exercise of varying intensities in individuals with NIDDM
-
Kang J, Kelley DE, Robertson RJ et al (1999) Substrate utilization and glucose turnover during exercise of varying intensities in individuals with NIDDM. Med Sci Sports Exerc 31:82-89
-
(1999)
Med Sci Sports Exerc
, vol.31
, pp. 82-89
-
-
Kang, J.1
Kelley, D.E.2
Robertson, R.J.3
-
16
-
-
0033645223
-
Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise
-
Blaak EE, van Aggel-Leijssen DPC, Wagenmakers AJM, Saris WHM, van Baak MA (2000) Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise. Diabetes 49:2102-2107
-
(2000)
Diabetes
, vol.49
, pp. 2102-2107
-
-
Blaak, E.E.1
van Aggel-Leijssen, D.P.C.2
Wagenmakers, A.J.M.3
Saris, W.H.M.4
van Baak, M.A.5
-
17
-
-
0036911624
-
Substrate utilization in non-obese type II diabetic patients at rest and during exercise
-
Borghouts LB, Wagenmakers AJM, Goyens PLL, Keizer HA (2002) Substrate utilization in non-obese type II diabetic patients at rest and during exercise. Clin Sci 103:559-566
-
(2002)
Clin Sci
, vol.103
, pp. 559-566
-
-
Borghouts, L.B.1
Wagenmakers, A.J.M.2
Goyens, P.L.L.3
Keizer, H.A.4
-
18
-
-
0029851728
-
Utilization of glycogen but not plasma glucose is reduced in individuals with NIDDM during mild-intensity exercise
-
Colberg SR, Hagberg JM, McCole SD, Zmuda JM, Thompson PD, Kelley DE (1996) Utilization of glycogen but not plasma glucose is reduced in individuals with NIDDM during mild-intensity exercise. J Appl Physiol 81:2027-2033
-
(1996)
J Appl Physiol
, vol.81
, pp. 2027-2033
-
-
Colberg, S.R.1
Hagberg, J.M.2
McCole, S.D.3
Zmuda, J.M.4
Thompson, P.D.5
Kelley, D.E.6
-
19
-
-
0021890981
-
Multiple disturbances of free fatty acid metabolism in noninsulin-dependent diabetes. Effect of oral hypoglycemic therapy
-
Taskinen MR, Bogardus C, Kennedy A, Howard BV (1985) Multiple disturbances of free fatty acid metabolism in noninsulin-dependent diabetes. Effect of oral hypoglycemic therapy. J Clin Invest 76:637-644
-
(1985)
J Clin Invest
, vol.76
, pp. 637-644
-
-
Taskinen, M.R.1
Bogardus, C.2
Kennedy, A.3
Howard, B.V.4
-
20
-
-
0025695163
-
Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus
-
Kelley DE, Mandarino LJ (1990) Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus. J Clin Invest 86:1999-2007
-
(1990)
J Clin Invest
, vol.86
, pp. 1999-2007
-
-
Kelley, D.E.1
Mandarino, L.J.2
-
21
-
-
0035514950
-
Plasma free fatty acid uptake and oxidation are already diminished in subjects at high risk for developing type 2 diabetes
-
Mensink M, Blaak EE, van Baak MA, Wagenmakers AJM, Saris WHM (2001) Plasma free fatty acid uptake and oxidation are already diminished in subjects at high risk for developing type 2 diabetes. Diabetes 50:2548-2554
-
(2001)
Diabetes
, vol.50
, pp. 2548-2554
-
-
Mensink, M.1
Blaak, E.E.2
van Baak, M.A.3
Wagenmakers, A.J.M.4
Saris, W.H.M.5
-
22
-
-
4644347353
-
Use of intramuscular triacylglycerol as a substrate source during exercise in humans
-
van Loon LJC (2004) Use of intramuscular triacylglycerol as a substrate source during exercise in humans. J Appl Physiol 97:1170-1187
-
(2004)
J Appl Physiol
, vol.97
, pp. 1170-1187
-
-
van Loon, L.J.C.1
-
23
-
-
0019570944
-
Glucoregulatory and metabolic response to exercise in obese noninsulin-dependent diabetes
-
Minuk HL, Vranic M, Marliss EB, Hanna AK, Albisser AM, Zinman B (1981) Glucoregulatory and metabolic response to exercise in obese noninsulin-dependent diabetes. Am J Physiol 240:E458-E464
-
(1981)
Am J Physiol
, vol.240
-
-
Minuk, H.L.1
Vranic, M.2
Marliss, E.B.3
Hanna, A.K.4
Albisser, A.M.5
Zinman, B.6
-
24
-
-
0029089150
-
Splanchnic and muscle metabolism during exercise in NIDDM patients
-
Martin IK, Katz A, Wahren J (1995) Splanchnic and muscle metabolism during exercise in NIDDM patients. Am J Physiol 269:E583-E590
-
(1995)
Am J Physiol
, vol.269
-
-
Martin, I.K.1
Katz, A.2
Wahren, J.3
-
25
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti KG, Zimmet PZ (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15:539-553
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
26
-
-
77049310862
-
The gross composition of the body
-
Siri WE (1956) The gross composition of the body. Adv Biol Med Phys 4:239-280
-
(1956)
Adv Biol Med Phys
, vol.4
, pp. 239-280
-
-
Siri, W.E.1
-
28
-
-
0016723939
-
Percutaneous needle biopsy of skeletal muscle in physiological and clinical research
-
Bergstrom J (1975) Percutaneous needle biopsy of skeletal muscle in physiological and clinical research. Scand J Clin Lab Invest 35:609-616
-
(1975)
Scand J Clin Lab Invest
, vol.35
, pp. 609-616
-
-
Bergstrom, J.1
-
29
-
-
0026128307
-
Table of nonprotein respiratory quotient: An update
-
Peronnet F, Massicotte D (1991) Table of nonprotein respiratory quotient: an update. Can J Sport Sci 16:23-29
-
(1991)
Can J Sport Sci
, vol.16
, pp. 23-29
-
-
Peronnet, F.1
Massicotte, D.2
-
30
-
-
0025194501
-
Recovery of labeled CO2 during the infusion of C-1- vs C-2-labeled acetate: Implications for tracer studies of substrate oxidation
-
Wolfe RR, Jahoor F (1990) Recovery of labeled CO2 during the infusion of C-1- vs C-2-labeled acetate: implications for tracer studies of substrate oxidation. Am J Clin Nutr 51:248-252
-
(1990)
Am J Clin Nutr
, vol.51
, pp. 248-252
-
-
Wolfe, R.R.1
Jahoor, F.2
-
31
-
-
0028809650
-
A new correction factor for use in tracer estimations of plasma fatty acid oxidation
-
Sidossis LS, Coggan AR, Gastaldelli A, Wolfe RR (1995) A new correction factor for use in tracer estimations of plasma fatty acid oxidation. Am J Physiol 269:E649-E656
-
(1995)
Am J Physiol
, vol.269
-
-
Sidossis, L.S.1
Coggan, A.R.2
Gastaldelli, A.3
Wolfe, R.R.4
-
32
-
-
0032534023
-
Validation of the [1,2-13C] acetate recovery factor for correction of [U-13C] palmitate oxidation rates in humans
-
Schrauwen P, van Aggel-Leijssen DPC, van Marken Lichtenbelt WD, van Baak MA, Gijsen AP, Wagenmakers AJM (1998) Validation of the [1,2-13C] acetate recovery factor for correction of [U-13C] palmitate oxidation rates in humans. J Physiol 513:215-223
-
(1998)
J Physiol
, vol.513
, pp. 215-223
-
-
Schrauwen, P.1
van Aggel-Leijssen, D.P.C.2
van Marken Lichtenbelt, W.D.3
van Baak, M.A.4
Gijsen, A.P.5
Wagenmakers, A.J.M.6
-
33
-
-
0033104611
-
Glucose kinetics during prolonged exercise in highly trained human subjects: Effect of glucose ingestion
-
Jeukendrup AE, Raben A, Gijsen A et al (1999) Glucose kinetics during prolonged exercise in highly trained human subjects: effect of glucose ingestion. J Physiol 515:579-589
-
(1999)
J Physiol
, vol.515
, pp. 579-589
-
-
Jeukendrup, A.E.1
Raben, A.2
Gijsen, A.3
-
34
-
-
0034796237
-
Recovery of (13)CO2 during rest and exercise after [1-(13)C] acetate, [2-(13)C]acetate, and NaH(13)CO3 infusions
-
Trimmer JK, Casazza GA, Horning MA, Brooks GA (2001) Recovery of (13)CO2 during rest and exercise after [1-(13)C] acetate, [2-(13)C]acetate, and NaH(13)CO3 infusions. Am J Physiol Endocrinol Metab 281:E683-E692
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Trimmer, J.K.1
Casazza, G.A.2
Horning, M.A.3
Brooks, G.A.4
-
35
-
-
4544329793
-
A modified PAS stain combined with immunofluorescence for quantitative analyses of glycogen in muscle sections
-
Schaart G, Hesselink RP, Keizer HA, van Kranenburg G, Drost MR, Hesselink MK (2004) A modified PAS stain combined with immunofluorescence for quantitative analyses of glycogen in muscle sections. Histochem Cell Biol 122:161-169
-
(2004)
Histochem Cell Biol
, vol.122
, pp. 161-169
-
-
Schaart, G.1
Hesselink, R.P.2
Keizer, H.A.3
van Kranenburg, G.4
Drost, M.R.5
Hesselink, M.K.6
-
38
-
-
0032765395
-
Glucose turnover and adipose tissue lipolysis are insulin-resistant in healthy relatives of type 2 diabetes patients: Is cellular insulin resistance a secondary phenomenon?
-
Eriksson JW, Smith U, Waagstein F, Wysocki M, Jansson PA (1999) Glucose turnover and adipose tissue lipolysis are insulin-resistant in healthy relatives of type 2 diabetes patients: is cellular insulin resistance a secondary phenomenon? Diabetes 48:1572-1578
-
(1999)
Diabetes
, vol.48
, pp. 1572-1578
-
-
Eriksson, J.W.1
Smith, U.2
Waagstein, F.3
Wysocki, M.4
Jansson, P.A.5
-
39
-
-
18844436264
-
Obesity and metabolic disease: Is adipose tissue the culprit?
-
Frayn KN (2005) Obesity and metabolic disease: is adipose tissue the culprit? Proc Nutr Soc 64:7-13
-
(2005)
Proc Nutr Soc
, vol.64
, pp. 7-13
-
-
Frayn, K.N.1
-
40
-
-
0024392514
-
Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance
-
Groop LC, Bonadonna RC, DelPrato S et al (1989) Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance. J Clin Invest 84:205-213
-
(1989)
J Clin Invest
, vol.84
, pp. 205-213
-
-
Groop, L.C.1
Bonadonna, R.C.2
DelPrato, S.3
-
41
-
-
0030896434
-
Effect of endurance training on fatty acid metabolism during whole body exercise
-
Martin WH (1997) Effect of endurance training on fatty acid metabolism during whole body exercise. Med Sci Sports Exerc 29:635-639
-
(1997)
Med Sci Sports Exerc
, vol.29
, pp. 635-639
-
-
Martin, W.H.1
-
43
-
-
0141857891
-
Fatty acid metabolism in obesity and type 2 diabetes mellitus
-
Blaak EE (2003) Fatty acid metabolism in obesity and type 2 diabetes mellitus. Proc Nutr Soc 62:753-760
-
(2003)
Proc Nutr Soc
, vol.62
, pp. 753-760
-
-
Blaak, E.E.1
-
44
-
-
2542593338
-
Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes
-
Schrauwen P, Hesselink MKC (2004) Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes. Diabetes 53:1412-1417
-
(2004)
Diabetes
, vol.53
, pp. 1412-1417
-
-
Schrauwen, P.1
Hesselink, M.K.C.2
-
45
-
-
0036310036
-
The fate of [U-(13)C] palmitate extracted by skeletal muscle in subjects with type 2 diabetes and control subjects
-
Blaak EE, Wagenmakers AJ (2002) The fate of [U-(13)C] palmitate extracted by skeletal muscle in subjects with type 2 diabetes and control subjects. Diabetes 51:784-789
-
(2002)
Diabetes
, vol.51
, pp. 784-789
-
-
Blaak, E.E.1
Wagenmakers, A.J.2
|