Na+-H+ exchanger regulatory factor 1 is a PDZ scaffold for the astroglial glutamate transporter GLAST

GLIA

Volumn 55, Issue 2, 2007, Pages 119-129

  Lee, Aven ^a   Rayfield, Andrew ^a   Hryciw, Deanne H ^a   Ma, Theingi Aung ^a   Wang, Dongsheng ^b   Pow, David ^c   Broer, Stefan ^d   Yun, Chris ^b   Poronnik, Philip ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NEWCASTLE   (Australia)

^d AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Astrocytes; GLAST; Glutamate transport; NHERF1; NHERF2

Indexed keywords

EXCITATORY AMINO ACID TRANSPORTER; EZRIN; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; MOESIN; PDZ PROTEIN; RADIXIN; SODIUM HYDROGEN EXCHANGER REGULATORY FACTOR 1; SODIUM HYDROGEN EXCHANGER REGULATORY FACTOR 2; SODIUM PROTON EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ASTROCYTE; BINDING AFFINITY; BRAIN CORTEX; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; MACROGLIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT;

ANIMALS; ASTROCYTES; BRAIN; CENTRAL NERVOUS SYSTEM; CEREBRAL ARTERIES; CYTOSKELETAL PROTEINS; ENDOTHELIAL CELLS; EXCITATORY AMINO ACID TRANSPORTER 1; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; MACROMOLECULAR SUBSTANCES; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; SODIUM-HYDROGEN ANTIPORTER;

EID: 33845944059     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20439     Document Type: Article

References (53)

1. Arriza J, Eliasof S, Kavanaugh M, Amara S. 1997. Excitatory amino acid transporter 5: A retinal glutamate transporter coupled to a chloride conductance. Proc Natl Acad Sci USA 94:4155-4160.
2. Benarroch E. 2005. Neuron-astrocyte interactions: Partnership for normal function and disease in the central nervous system. Mayo Clin Proc 80:1326-1338.
3. Berger U, DeSilva T, Chen W, Rosenberg P. 2005. Cellular and subcellular mRNA localization of glutamate transporter isoforms GLT1a and GLT1b in rat brain by in situ hybridization. J Comp Neurol 492:78-89.
4. Bretscher A, Chambers D, Nguyen R, Reczek D. 2000. ERM-Merlin and EBP50 protein families in plasma membrane organization and function. Annu Rev Cell Dev Biol 16:113-143.
5. Brone B, Eggermont J. 2005. PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes. Am J Physiol Cell Physiol 288:C20-29.
6. Chen W, Mahadomrongkul V, Berger U, Bassan M, DeSilva T, Tanaka K, Irwin N, Aoki C, Rosenberg PA. 2004. The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons. J Neurosci 24:1136-1148.
7. Conradt M, Stoffel W. 1997. Inhibition of the high-affinity brain glutamate transporter GLAST-1 via direct phosphorylation. J Neurochem 68:1244-1251.
8. Danbolt N. 2001. Glutamate uptake. Prog Neurobiol 65:1-105.
9. + exchanger regulatory factor-1 complexes. Am J Physiol Cell Physiol 289:C159-167.
10. + exchanger regulatory factor-1. J Biol Chem 281:1796-1807.
11. + exchange regulatory factor. Endocrinology 140:2976-2982.
12. Fam S, Paquet M, Castleberry A, Oller H, Lee C, Traynelis S, Smith Y, Yun C, Hall R. 2005. P2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2. Proc Natl Acad Sci USA 102:8042-8047.
13. Fonnum F. 1984. Glutamate: A neurotransmitter in mammalian brain. J Neurochem 42:1-11.
14. Fouassier L, Yun C, Fitz J, Doctor R. 2000. Evidence for ezrin-radixinmoesin-binding phosphoprotein 50 (EBP50) self-association through PDZ-PDZ interactions. J Biol Chem 275:25039-25045.
15. Furuta A, Rothstein J, Martin L. 1997. Glutamate transporter protein subtypes are expressed differentially during rat CNS development. J Neurosci 17:8363-8375.
16. Gatto C, Walker B, Lambert S. 2003. Local ERM activation and dynamic growth cones at Schwann cell tips implicated in efficient formation of nodes of Ranvier. J Cell Biol 162:489-98.
17. +-dependent high affinity glutamate/aspartate transporter in cultured Bergmann glia by phorbol esters. J Neurosci Res 50:585-590.
18. + exchange. Nature 392:626-630.
19. i cotransporters. Proc Natl Acad Sci USA 99:11957-11962.
20. Hernando N, Wagner C, Gisler S, Biber J, Murer H. 2004. PDZ proteins and proximal ion transport. Curr Opin Nephrol Hypertens 13:569-574.
21. Jackson M, Song W, Liu M, Jin L, Dykes-Hoberg M, Lin C, Bowers W, Federoff H, Sternweis P, Rothstein J. 2001. Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Nature 410:89-93.
22. + exchanger regulatory factors 1 and 2 in the rat cochlea. Cell Tissue Res 323:53-70.
23. Lamprecht G, Weinman E, Yun C. 1998. The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3. J Biol Chem 273:29972-29978.
24. Lehre K, Danbolt N. 1998. The number of glutamate transporter subtype molecules at glutamatergic synapses: Chemical and stereological quantification in young adult rat brain. J Neurosci 18:8751-8757.
25. Lehre K, Levy L, Ottersen O, Storm-Mathisen J, Danbolt N. 1995. Differential expression of two glial glutamate transporters in the rat brain: Quantitative and immunocytochemical observations. J Neurosci 15(3 Pt 1):1835-1853.
26. + exchange regulatory factor-2. Am J Physiol Renal Physiol 282:F1129-1139.
27. + exchange regulatory factor. J Biol Chem 277:22925-22933.
28. MacAulay N, Hamann S, Zeuthen T. 2004. Water transport in the brain: Role of cotransporters. Neuroscience 129:1031-1044.
29. + exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling. Nature 417:858-861.
30. Marcaggi P, Attwell D. 2004. Role of glial amino acid transporters in synaptic transmission and brain energetics. Glia 47:217-225.
31. Marie H, Attwell D. 1999. C-terminal interactions modulate the affinity of GLAST glutamate transporters in salamander retinal glial cells. J Physiol 520 Pt 2:393-397.
32. + exchanger regulatory factor potentiates receptor activity. Mol Cell Biol 20:8352-8363.
33. Nawrot M, West K, Huang J, Possin D, Bretscher A, Crabb J, Saari J. 2004. Cellular retinaldehyde-binding protein interacts with ERM-binding phosphoprotein 50 in retinal pigment epithelium. Invest Ophthalmol Vis Sci 45:393-401.
34. Neely J, Amiry-Moghaddam M, Ottersen O, Froehner S, Agre P, Adams M. 2001. Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein. Proc Natl Acad Sci USA 98:14108-14113.
35. Ogura T, Furukawa T, Toyozaki T, Yamada K, Zheng Y, Katayama Y, Nakaya H, Inagaki N. 2002. C1C-3B, a novel C1C-3 splicing variant that interacts with EBP50 and facilitates expression of CFTR-regulated ORCC. FASEB J 16:863-865.
36. + exchanger regulatory factor 2 (NHERF-2) in mouse brain. J Comp Neurol 494:752-762.
37. Pow D, Barnett N. 1999. Changing patterns of spatial buffering of glutamate in developing rat retinae are mediated by the Muller cell glutamate transporter GLAST. Cell Tissue Res 297:57-66.
38. Pow D, Hendrickson A. 1999. Distribution of the glycine transporter glyt1 in mammalian and nonmammalian retinae. Vis Neurosci 16:231-239.
39. Ramesh V. 2004. Merlin and the ERM proteins in Schwann cells, neurons and growth cones. Nat Rev Neurosci 5:462-470.
40. Reye P, Sullivan R, Scott H, Pow D. 2002. Distribution of two splice variants of the glutamate transporter GLT-1 in rat brain and pituitary. Glia 38:246-255.
41. Shenolikar S, Minkoff C, Steplock D, Evangelista C, Liu M, Weinman E. 2001. N-terminal PDZ domain is required for NHERF dimerization. FEBS Lett 489:233-236.
42. Shenolikar S, Voltz J, Cunningham R, Weinman E. 2004. Regulation of ion transport by the NHERF family of PDZ proteins. Physiology 19:362-369.
43. Shenolikar S, Voltz J, Minkoff C, Wade J, Weinman E. 2002. Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting. Proc Natl Acad Sci USA 99:11470-11475.
44. Song X, Zhao Y, Narcisse L, Duffy H, Kress Y, Lee S, Brosnan C. 2005. Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture. Glia 49:418-429.
45. Stemmer-Rachamimov A, Wiederhold T, Nielsen G, James M, Pinney-Michalowski D, Roy J, Cohen W, Ramesh V, Louis D. 2001. NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas. Am J Pathol 158:57-62.
46. Susarla B, Seal R, Zelenaia O, Watson D, Wolfe J, Amara S, Robinson M. 2004. Differential regulation of GLAST immunoreactivity and activity by protein kinase C: Evidence for modification of amino and carboxyl termini. J Neurochem 91:1151-1193.
47. Tang Y, Tang J, Chen Z, Trost C, Flockerzi V, Li M, Ramesh V, Zhu M. 2002. Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF. J Biol Chem 275:37559-37564.
48. Torres G, Yao W, Mohn A, Quan H, Kim K, Levey A, Staudinger J, Caron M. 2001. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron 30:121-134.
49. Wang S, Raab R, Schatz P, Guggino W, Li M. 1998. Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR). FEBS Lett 427:103-108.
50. + exchanger. J Clin Invest 95:2143-2149.
51. Williams S, Sullivan R, Scott H, Finkelstein D, Colditz P, Lingwood B, Dodd P, Pow D. 2005. Glial glutamate transporter expression patterns in brains from multiple mammalian species. Glia 49:520-541.
52. + exchanger isoform 3 revisited. The roles of SGK1 and NHERF2. J Biol Chem 277:7676-7683.
53. + exchanger, NHE3, requires an associated regulatory protein. Proc Natl Acad Sci USA 94:3010-3015.