Regulation of the Na+-dependent high affinity glutamate/aspartate transporter in cultured Bergmann gila by phorbol esters

Journal of Neuroscience Research

Volumn 50, Issue 4, 1997, Pages 585-590

  Gonzalez M I ^a   Ortega, A ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Bergmann glia; L aspartate; L glutamate; Neurotransmitter transporters; Phorbol esters; Phosphorylation; PKC

Indexed keywords

ASPARTIC ACID; BUCLADESINE; GLUTAMIC ACID; PHORBOL 13 ACETATE 12 MYRISTATE; STAUROSPORINE;

AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; CHICK EMBRYO; EMBRYO; GENE EXPRESSION REGULATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; BUCLADESINE; CELLS, CULTURED; CHICK EMBRYO; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; NEUROGLIA; NEUROTRANSMITTER AGENTS; PROTEIN KINASE C; SODIUM; SYNAPSES; TETRADECANOYLPHORBOL ACETATE; TRITIUM;

EID: 1842329222     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19971115)50:4<585::AID-JNR9>3.0.CO;2-A     Document Type: Article

References (25)

1. Anderson GM, Horne WC (1992): Activators of protein kinase C decrease serotonin transport in human platelets. Biochim Biophys Acta 1137:331-337.
2. Baranes D, Razin E (1991): Protein kinase C regulates proliferation of mast cells and the expression of the mRNAs of fos and jun proto-oncogenes during activation by IgE-Ag or calcium ionophore A23187. Blood 78:2354-2364.
3. Borowsky B, Hoffman B (1995): Neurotransmitter transporters: Molecular biology, function, and regulation. Int Rev Neurobiol 38:139-199.
4. Bradford MM (1976): A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of dye binding. Anal Biochem 72:248-254.
5. Casado M, Zafra F, Aragón C, Giménez C (1991): Activation of high-affinity uptake of glutamate by phorbol esters in primary glial cell cultures. J Neurochem 57:1185-1190.
6. Casado M, Bendahan A, Zafra F, Danbolt NC, Aragón C, Giménez C, Kanner BI (1993): Phosphorylation and modulation of brain glutamate transporters by protein kinase C. J Biol Chem 268:27313-27317.
7. 6 glioma cells. J Neurochem 64:818-824.
8. +-dependent L-glutamate transport activity in C6 glioma cells by phorbol ester. J Neurochem 67:508-516.
9. Farrukh A, Chaudhry FA, Lehre KP, van Lookeren Campagne, Ottersen OP, Danbolt NC, Storm-Mathisen J (1995): Glutamate transporters in glial plasma membranes: Highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 15:711-720.
10. Hagiwara T, Tanaka K, Takai S, Maeno-Hirichi Y, Mukainaka Y, Wada K (1996): Genomic organization, promoter analysis, and chromosomal localization of the gene for the mouse glial high-affinity glutamate transporter Slc 1a3. Genomics 33:508-515.
11. Kanai Y, Hediger MA (1992): Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360:467-471.
12. Kettenmann H (1996): Beyond the neuronal circuitry. Trends Neurosci 19:305-306.
13. Lopez T, Onega A (1994): AMPA/KA receptors in Bergmann glia. NeuroReport 5:504-506.
14. Müller T, Kettenmann H (1995): Physiology of Bergmann glial cells. Int Rev Neurobiol 38:341-359.
15. Ortega A, Eshhar N, Teichberg VI (1991): Properties of kainate receptor/channels on Bergmann glia. Neuroscience 41:335-349.
16. Otori Y, Shimada S, Tanaka K, Ishimoto I, Tano Y, Tohyama M (1994): Marked increase in glutamate-aspartate transporter (GLAST/ GluT-1) mRNA following transient retinal ischemia. Mol Brain Res 27:310-314.
17. Pines G, Danbolt NC, Bjøras M, Zhang Y, Bendaham A, Eide L, Koepsell H, Storm-mathisen J, Seeberg E, Kanner BI (1992): Cloning and expression of a rat brain L-glutamate transporter. Nature 360:464-467.
18. Pisano P, Samuel D, Nieoullon A, Kerkerian-LeGoff L (1996): Activation of the adenylate cyclase-dependent protein kinase pathway increases high affinity glutamate uptake into rat striatal synaptosomes. Neuropharmacology 35:542-547.
19. Rothstein JD, Martin L, Leveley AI, Dykes-Hoberg M, Jin L, Wu D, Nash N, Kuncl RW (1994): Localization of neuronal and glial glutamate transporters. Neuron 13:713-725.
20. +-dependent glutamate/aspartate transporter from cultured Bergmann glia. NeuroReport 6:2041-2044.
21. Sánchez G, Ortega A (1994): AMPA/KA receptor induced AP-1 DNA binding activity in cultured Bergmann glia cells. NeuroReport 5:1209-1212.
22. Simantov R (1995): Neurotransporters: Regulation, involvement in neurotoxicity, and the usefulness of antisense nucleic acids. Biochem Pharmacol 50:435-442.
23. +-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci USA 90:6591-6595.
24. Watkins JC, Evans RH (1981): Excitatory amino acid transmitters. Annu Rev Pharmacol Toxicol 21:165-204.
25. Zerangue N, Arriza JL, Amara SG, Kavanaugh MP (1995): Differential modulation of human glutamate transporter subtypes by arachidonic acid. J Biol Chem 270:6433-6435.