The role of a conserved serine residue within hydrogen bonding distance of FAD in redox properties and the modulation of catalysis by Ca 2+/calmodulin of constitutive nitric-oxide synthases

Journal of Biological Chemistry

Volumn 281, Issue 45, 2006, Pages 34246-34257

  Panda, Satya Prakash ^a   Ying, Tong Gao ^a   Roman, Linda J ^a   Martásek, Pavel ^a,c   Salerno, John C ^b   Masters, Bettie Sue S ^a  

^a University of Texas Health Science Center   (United States)

^b KENNESAW STATE UNIVERSITY   (United States)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CATALYSIS; CRYSTAL STRUCTURE; HYDROGEN BONDS; POTASSIUM COMPOUNDS; REDOX REACTIONS;

ENDOTHELIAL NITRIC-OXIDE SYNTHASE (ENOS); HYDROGEN BONDING DISTANCE; NEURONAL NITRIC-OXIDE SYNTHASE (NNOS); SERINE RESIDUES;

PROTEINS;

CALCIUM ION; CALMODULIN; CYTOCHROME C; FERREDOXIN; FLAVINE ADENINE NUCLEOTIDE; NITRIC OXIDE SYNTHASE; POTASSIUM FERRICYANIDE; SERINE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ELECTRON TRANSPORT; ENDOTHELIUM; ENZYME ACTIVITY; HYDROGEN BOND; KINETICS; MUTATION; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CALCIUM; CALMODULIN; CATALYSIS; ELECTRON TRANSPORT; FLAVIN-ADENINE DINUCLEOTIDE; HUMANS; HYDROGEN BONDING; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NADP; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE III; OXIDATION-REDUCTION; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; THREONINE;

EID: 33845927882     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M601041200     Document Type: Article

References (65)

1. Roman, L. J., Martásek, P., and Masters, B. S. S. (2002) Chem. Rev. 102, 1179-1190
2. Stuehr, D. J., Santolini, J., Wang, Z. Q., Wei, C. C., and Adak, S. (2004) J. Biol. Chem. 279, 36167-36170
3. Moncada, S., and Higgs, A. (1993) N. Engl. J. Med. 329, 2002-2012
4. Stuehr, D. J., Cho, H. J., Kwon, N. S., Weise, M. F., and Nathan, C. F. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 7773-7777
5. Li, H., Shimizu, H., Flinspach, M., Jamal, J., Yang, W., Xian, M., Cai, T., Wen, E. Z., Jia, Q., Wang, P. G., and Poulos, T. L. (2002) Biochemistry 41, 13868-13875
6. Flinspach, M., Li, H., Jamal, J., Yang, W., Huang, H., Silverman, R. B., and Poulos, T. L. (2004) Biochemistry 43, 5181-5187
7. Raman, C. S., Li, H., Martásek, P., Kral, V., Masters, B. S. S., and Poulos, T. L. (1998) Cell 95, 939-950
8. Fischmann, T. O., Hruza, A., Niu, X. D., Fossetta, J. D., Lunn, C. A., Dolphin, E., Prongay, A. J., Reichert, P., Lundell, D. J., Narula, S. K., and Weber, P. C. (1999) Nat. Struct. Biol. 6, 233-242
9. Crane, B. R., Arvai, A. S., Ghosh, D. K., Wu, C., Getzoff, E. D., Stuehr, D. J., and Tainer, J. A. (1998) Science 279, 2121-2126
10. Bredt, D. S., Hwang, P. M., Glatt, C. E., Lowenstein, C., Reed, R. R., and Snyder, S. H. (1991) Nature 351, 714-718
11. Salerno, J. C., Harris, D. E., Irizarry, K., Patel, B., Morales, A. J., Smith, S. M., Martásek, P., Roman, L. J., Masters, B. S. S., Jones, C. L., Weissman, B. A., Lane, P., Liu, Q., and Gross, S. S. (1997) J. Biol. Chem. 272, 29769-29777
12. Roman, L. J., Martásek, P., Miller, R. T., Harris, D. E., de La Garza, M. A., Shea, T. M., Kim, J. J., and Masters, B. S. S. (2000) J. Biol. Chem. 275, 29225-29232
13. Roman, L. J., Miller, R. T., de La Garza, M. A., Kim, J. J., and Masters, B. S. S. (2000) J. Biol. Chem. 275, 21914-21919
14. Lane, P., and Gross, S. S. (2002) J. Biol. Chem. 277, 19087-19094
15. Jáchymová, M., Martásek, P., Panda, S., Roman, L. J., Panda, M., Shea, T. M., Ishimura, Y., Kim, J. J., and Masters, B. S. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 15833-15838
16. Wang, M., Roberts, D. L., Paschke, R., Shea, T. M., Masters, B. S. S., and Kim, J. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 8411-8416
17. Zhang, J., Martásek, P., Paschke, R., Shea, T., Masters, B. S. S., and Kim, J. J. (2001) J. Biol. Chem. 276, 37506-37513
18. Garcin, E. D., Bruns, C. M., Lloyd, S. J., Hosfield, D. J., Tiso, M., Gachhui, R., Stuehr, D. J., Tainer, J. A., and Getzoff, E. D. (2004) J. Biol. Chem. 279, 37918-37927
19. Shen, A. L., Porter, T. D., Wilson, T. E., and Kasper, C. B. (1989) J. Biol. Chem. 264, 7584-7589
20. Sem, D. S., and Kasper, C. B. (1992) Biochemistry 31, 3391-3398
21. Shen, A. L., and Kasper, C. B. (1995) J. Biol. Chem. 270, 27475-27480
22. Shen, A. L., and Kasper, C. B. (1996) Biochemistry 35, 9451-9459
23. Shen, A. L., and Kasper, C. B. (2000) J. Biol. Chem. 275, 41087-41091
24. Porter, T. D., and Kasper, C. B. (1986) Biochemistry 25, 1682-1687
25. Michael, S. F. (1994) BioTechniques 16, 410-412
26. Martásek, P., Liu, Q., Liu, J., Roman, L. J., Gross, S. S., Sessa, W. C., and Masters, B. S. S. (1996) Biochem. Biophys. Res. Commun. 219, 359-365
27. Roman, L. J., Sheta, E. A., Martásek, P., Gross, S. S., Liu, Q., and Masters, B. S. S. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8428-8432
28. Zhang, M., and Vogel, H. J. (1994) Biochemistry 33, 1163-1171
29. Paul, K. G., Theorell, H., and Akeson, A. (1953) Acta Chem. Scand. 7, 1284
30. Rieske, J. S. (1967) Methods Enzymol. 10, 488-493
31. Faeder, E. J., and Siegel, L. M. (1973) Anal. Biochem. 53, 332-336
32. Aliverti, A., Curti, B., and Vanoni, M. A. (1999) in Flavoprotein Protocols (Chapman, S. K., and Reid, G. A., eds) pp. 9-23, Humana Press, Totowa, NJ
33. Masters, B. S. S., Williams, C. H. J., and Kamin, H. (1967) Methods Enzymol. 10, 565-573
34. Miller, R. T., Martásek, P., Omura, T., and Masters, B. S. S. (1999) Biochem. Biophys. Res. Commun. 265, 184-188
35. Kelm, M., Feelisch, M., Spahr, R., Piper, H. M., Noack, E., and Schrader, J. (1988) Biochem. Biophys. Res. Commun. 154, 236-244
36. Dutton, P. L. (1978) Methods Enzymol. 54, 411-435
37. Gao, Y. T., Smith, S. M., Weinberg, J. B., Montgomery, H. J., Newman, E., Guillemette, J. G., Ghosh, D. K., Roman, L. J., Martásek, P., and Salerno, J. C. (2004) J. Biol. Chem. 279, 18759-18766
38. Dunford, A. J., Marshall, K. R., Munro, A. W., and Scrutton, N. S. (2004) Eur. J. Biochem. 271, 2548-2560
39. Aliverti, A., Bruns, C. M., Pandini, V. E., Karplus, P. A., Vanoni, M. A., Curti, B., and Zanetti, G. (1995) Biochemistry 34, 8371-8379
40. Kimura, S., Kawamura, M., and Iyanagi, T. (2003) J. Biol. Chem. 278, 3580-3589
41. Hubbard, P. A., Shen, A. L., Paschke, R., Kasper, C. B., and Kim, J. J. (2001) J. Biol. Chem. 276, 29163-29170
42. Roman, L. J., McLain, J., and Masters, B. S. S. (2003) J. Biol. Chem. 278, 25700-25707
43. Alexander, L. M., Hersh, L. B., and Masters, B. S. (1980) in Microsomes, Drug Oxidations, and Chemical Carcinogenesis (Coon, M. J., Conney, A. H., Estabrook, R. W., Gelboin, H. V., Gillette, J. R., and O'Brien, P. J., eds) pp. 285-288, Academic Press, Inc., New York
44. Vermilion, J. L., Ballou, D. P., Massey, V., and Coon, M. J. (1981) J. Biol. Chem. 256, 266-277
45. Kurzban, G. P., Howarth, J., Palmer, G., and Strobel, H. W. (1990) J. Biol. Chem. 265, 12272-12279
46. Martásek, P., Miller, R. T., Roman, L. J., Shea, T., and Masters, B. S. S. (1999) Methods Enzymol. 301, 70-78
47. Knight, K., and Scrutton, N. S. (2002) Biochem. J. 367, 19-30
48. Ghosh, D. K., Holliday, M. A., Thomas, C., Weinberg, J. B., Smith, S. M. E., and Salerno, J. C. (2006) J. Biol. Chem. 281, 14173-14183
49. Massey, V. (2000) Biochem. Soc. Trans. 28, 283-296
50. Fraaije, M. W., and Mattevi, A. (2000) Trends Biochem. Sci 25, 126-132
51. Karplus, P. A., Walsh, K. A., and Herriott, J. R. (1984) Biochemistry 23, 6576-6583
52. Craig, D. H., Chapman, S. K., and Daff, S. (2002) J. Biol. Chem. 277, 33987-33994
53. Roman, L. J., and Masters, B. S. S. (2006) J. Biol. Chem. 281, 23111-23118
54. Faro, M., Gómez-Moreno, C., Stankovich, M. T., and Medina, M. (2002) Eur. J. Biochem. 269, 2656-2661
55. Ghosh, D. K., and Salerno, J. C. (2003) Front. Biosci. 8, d193-d209
56. Lamas, S., Marsden, P. A., Li, G. K., Tempst, P., and Michel, T. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 6348-6352
57. Xie, Q. W., Cho, H. J., Calaycay, J., Mumford, R. A., Swiderek, K. M., Lee, T. D., Ding, A., Troso, T., and Nathan, C. (1992) Science 256, 225-228
58. Ruettinger, R. T., Wen, L. P., and Fulco, A. J. (1989) J. Biol. Chem. 264, 10987-10995
59. Ohgiya, S., Shinriki, N., Kamataki, T., and Ishizaki, K. (1994) Biochim. Biophys. Acta 1186, 137-141
60. Pietrini, G., Carrera, P., and Borgese, N. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 7246-7250
61. Leclerc, D., Wilson, A., Dumas, R., Gafuik, C., Song, D., Watkins, D., Heng, H. H., Rommens, J. M., Scherer, S. W., Rosenblatt, D. S., and Gravel, R. A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3059-3064
62. Vaucheret, H., Vincentz, M., Kronenberger, J., Caboche, M., and Rouze, P. (1989) Mol. Gen. Genet. 216, 10-15
63. Makino, K., Yokoyama, K., Kubota, Y., Yutsudo, C. H., Kimura, S., Kurokawa, K., Ishii, K., Hattori, M., Tatsuno, I., Abe, H., Iida, T., Yamamoto, K., Onishi, M., Hayashi, T., Yasunaga, T., Honda, T., Sasakawa, C., and Shinagawa, H. (1999) Genes Genet. Syst. 74, 227-239
64. Suh, Y. A., Arnold, R. S., Lassegue, B., Shi, J., Xu, X., Sorescu, D., Chung, A. B., Griendling, K. K., and Lambeth, J. D. (1999) Nature 401, 79-82
65. Dujon, B., Alexandraki, D., Andre, B., Ansorge, W., Baladron, V., Ballesta, J. P., Banrevi, A., Bolle, P. A., Bolotin-Fukuhara, M., Bossier, P., et al. (1994) Nature 369, 371-378