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Volumn 71, Issue 1, 2007, Pages 314-322

RasGRP1 confers the phorbol ester-sensitive phenotype to EL4 lymphoma cells

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN RASGRP1; RAS PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 33845894177     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.028639     Document Type: Article
Times cited : (10)

References (43)
  • 2
    • 33644856401 scopus 로고    scopus 로고
    • Identification of novel in vito Raf-2 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase
    • Balan V, Leicht DT, Zhu J, Balan K, Kaplun A, Singh-Gupta V, Qin J, Ruan H, Comb MJ, and Tzivion G (2006) Identification of novel in vito Raf-2 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase. Mol Biol Cell 17:1141-1153.
    • (2006) Mol Biol Cell , vol.17 , pp. 1141-1153
    • Balan, V.1    Leicht, D.T.2    Zhu, J.3    Balan, K.4    Kaplun, A.5    Singh-Gupta, V.6    Qin, J.7    Ruan, H.8    Comb, M.J.9    Tzivion, G.10
  • 3
    • 0030293921 scopus 로고    scopus 로고
    • Effects of phorbol ester on phospholipase D and mitogen-activated protein kinase activities in T-lymphocyte cell lines
    • Bradshaw CD, Ella KM, Qi C, Sansbury HM, Wisehart-Johnson AE, and Meier KE (1996) Effects of phorbol ester on phospholipase D and mitogen-activated protein kinase activities in T-lymphocyte cell lines. Immunol Letts 53:69-76.
    • (1996) Immunol Letts , vol.53 , pp. 69-76
    • Bradshaw, C.D.1    Ella, K.M.2    Qi, C.3    Sansbury, H.M.4    Wisehart-Johnson, A.E.5    Meier, K.E.6
  • 4
    • 0036905264 scopus 로고    scopus 로고
    • Move over protein kinase C, you've got company: Alternative cellular effectors of diacylglycerol and phorbol esters
    • Brose N and Rosenmund C (2002) Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters. J Cell Sci 115:4399-4411.
    • (2002) J Cell Sci , vol.115 , pp. 4399-4411
    • Brose, N.1    Rosenmund, C.2
  • 5
    • 0031018555 scopus 로고    scopus 로고
    • Evidence for different mechanisms of growth inhibition of T-cell lymphoma by phorbol esters and concanavalin A
    • Desrivieres S, Volarevic S, Mercep L, and Ferrari S (1997) Evidence for different mechanisms of growth inhibition of T-cell lymphoma by phorbol esters and concanavalin A. J Biol Chem 272:2470-2476.
    • (1997) J Biol Chem , vol.272 , pp. 2470-2476
    • Desrivieres, S.1    Volarevic, S.2    Mercep, L.3    Ferrari, S.4
  • 7
    • 0032524389 scopus 로고    scopus 로고
    • RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs
    • Ebinu JO, Bottorff DA, Chan EYW, Stang SL, Dunn RJ, and Stone JC (1998) RasGRP, a Ras guanyl nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Science (Wash DC) 280:1082-1086.
    • (1998) Science (Wash DC) , vol.280 , pp. 1082-1086
    • Ebinu, J.O.1    Bottorff, D.A.2    Chan, E.Y.W.3    Stang, S.L.4    Dunn, R.J.5    Stone, J.C.6
  • 10
    • 0027182750 scopus 로고
    • Effects of phorbol ester on mitogen-activated protein kinase kinase activity in wild-type and phorbol ester-resistant EL4 thymoma cells
    • Gause KC, Homma MK, Licciardi KA, Seger R, Ahn NG, Peterson MJ, Krebs EG, and Meier KE (1993) Effects of phorbol ester on mitogen-activated protein kinase kinase activity in wild-type and phorbol ester-resistant EL4 thymoma cells. J Biol Chem 268:16124-16129.
    • (1993) J Biol Chem , vol.268 , pp. 16124-16129
    • Gause, K.C.1    Homma, M.K.2    Licciardi, K.A.3    Seger, R.4    Ahn, N.G.5    Peterson, M.J.6    Krebs, E.G.7    Meier, K.E.8
  • 11
    • 0023143768 scopus 로고
    • Phorbol esters induce interleukin 2 mRNA in sensitive but not in resistant EL4 cells
    • Harrison JR, Lynch KR, and Sando JJ (1987) Phorbol esters induce interleukin 2 mRNA in sensitive but not in resistant EL4 cells. J Biol Chem 262:234-238.
    • (1987) J Biol Chem , vol.262 , pp. 234-238
    • Harrison, J.R.1    Lynch, K.R.2    Sando, J.J.3
  • 12
    • 0036547350 scopus 로고    scopus 로고
    • Expression of a catalytically inactive form of diacylglycerol kinase α induces sustained signaling through Ras-GRP
    • Jones DR, Sanjuan MA, Stone JC, and Merida I (2002) Expression of a catalytically inactive form of diacylglycerol kinase α induces sustained signaling through Ras-GRP. FASEB J 16:595-597.
    • (2002) FASEB J , vol.16 , pp. 595-597
    • Jones, D.R.1    Sanjuan, M.A.2    Stone, J.C.3    Merida, I.4
  • 13
    • 0036209077 scopus 로고    scopus 로고
    • Kazanietz MG (2002) Novel nonkinase phorbol ester receptors: the C1 domain connection [published erratum appears in Mol Pharmacol 61:1265, 2002]. Mol Pharmacol 61:759-767.
    • Kazanietz MG (2002) Novel "nonkinase" phorbol ester receptors: the C1 domain connection [published erratum appears in Mol Pharmacol 61:1265, 2002]. Mol Pharmacol 61:759-767.
  • 14
    • 0022500836 scopus 로고
    • Substrates for protein kinase C in cytosol of EL4 mouse thymoma cells
    • Kramer CM and Sando JJ (1986) Substrates for protein kinase C in cytosol of EL4 mouse thymoma cells. Canc Res 46:3040-3045.
    • (1986) Canc Res , vol.46 , pp. 3040-3045
    • Kramer, C.M.1    Sando, J.J.2
  • 15
    • 0034646637 scopus 로고    scopus 로고
    • Phosphorylaton of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells
    • Ku H and Meier KE (2000) Phosphorylaton of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells. J Biol Chem 275:11333-11340.
    • (2000) J Biol Chem , vol.275 , pp. 11333-11340
    • Ku, H.1    Meier, K.E.2
  • 16
    • 0037530531 scopus 로고    scopus 로고
    • L, Yang Y, Wong GW, and Stevens RL (2003) Mast cells in airway hyporesponsive C3H/HeJ mice express a unique isoform of the signaling protien Ras guanine nucleotide releasing protein 4 that is unresponsive to diacylglycerol and phorbol esters. J Immunol 171:390-397.
    • L, Yang Y, Wong GW, and Stevens RL (2003) Mast cells in airway hyporesponsive C3H/HeJ mice express a unique isoform of the signaling protien Ras guanine nucleotide releasing protein 4 that is unresponsive to diacylglycerol and phorbol esters. J Immunol 171:390-397.
  • 17
    • 0034061660 scopus 로고    scopus 로고
    • The guanine nucleotide exchange factor RasGRP is a high-affinity target for diacylglycerol and phorbol esters
    • Lorenzo PS, Beheshti M, Pettit GR, Stone JC, and Blumberg PM (2000) The guanine nucleotide exchange factor RasGRP is a high-affinity target for diacylglycerol and phorbol esters. Mol Pharmacol 57:840-846.
    • (2000) Mol Pharmacol , vol.57 , pp. 840-846
    • Lorenzo, P.S.1    Beheshti, M.2    Pettit, G.R.3    Stone, J.C.4    Blumberg, P.M.5
  • 19
    • 0031007664 scopus 로고    scopus 로고
    • Deficient tyrosine phosphorylation of c-Cbl and associated proteins in phorbol ester-resistant EL4 mouse thymoma cells
    • Luo X and Sando JJ (1997) Deficient tyrosine phosphorylation of c-Cbl and associated proteins in phorbol ester-resistant EL4 mouse thymoma cells. J Biol Chem 272:12221-12228.
    • (1997) J Biol Chem , vol.272 , pp. 12221-12228
    • Luo, X.1    Sando, J.J.2
  • 20
    • 0346463045 scopus 로고    scopus 로고
    • Madani S, Hichami A, Charkaoui-Malki M, and Khan NA (2004) Diacylglycerols containing Omega 3 and Omega 6 fatty acids bind to RasGRP and modulate MAP kinase activation [published erratum appears in J Biol Chem 279:23846, 2004]. J Biol Chem 279:1176-1183.
    • Madani S, Hichami A, Charkaoui-Malki M, and Khan NA (2004) Diacylglycerols containing Omega 3 and Omega 6 fatty acids bind to RasGRP and modulate MAP kinase activation [published erratum appears in J Biol Chem 279:23846, 2004]. J Biol Chem 279:1176-1183.
  • 22
    • 26444483956 scopus 로고    scopus 로고
    • A requirement for sustained ERK signaling during thymocyte positive selection in vivo
    • McNeil LK, Starr TK, and Hogquist KA (2005) A requirement for sustained ERK signaling during thymocyte positive selection in vivo. Proc Natl Acad Sci USA 102:13574-13579.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13574-13579
    • McNeil, L.K.1    Starr, T.K.2    Hogquist, K.A.3
  • 23
    • 0025967719 scopus 로고
    • Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells
    • Meier KE, Licciardi KA, Haystead TAJ, and Krebs EG (1991) Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells. J Biol Chem 256:1914-1920.
    • (1991) J Biol Chem , vol.256 , pp. 1914-1920
    • Meier, K.E.1    Licciardi, K.A.2    Haystead, T.A.J.3    Krebs, E.G.4
  • 25
    • 33746214860 scopus 로고    scopus 로고
    • RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development
    • Priatel JJ, Chen X, Chanji S, Abraham N, and Teh HS (2006) RasGRP1 transmits prodifferentiation TCR signaling that is crucial for CD4 T cell development. J Immunol 177:1470-1480.
    • (2006) J Immunol , vol.177 , pp. 1470-1480
    • Priatel, J.J.1    Chen, X.2    Chanji, S.3    Abraham, N.4    Teh, H.S.5
  • 26
    • 22844435317 scopus 로고    scopus 로고
    • A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms α and δ as well as selectivity for RasGRP compared with PKCα
    • Pu Y, Perry NA, Yang D, Lewin NE, Kedei N, Braun DC, Choi SH, Blumberg PM, Garfield SH, Stone JC, et al. (2005) A novel diacylglycerol-lactone shows marked selectivity in vitro among C1 domains of protein kinase C (PKC) isoforms α and δ as well as selectivity for RasGRP compared with PKCα. J Biol Chem 280:27329-27338.
    • (2005) J Biol Chem , vol.280 , pp. 27329-27338
    • Pu, Y.1    Perry, N.A.2    Yang, D.3    Lewin, N.E.4    Kedei, N.5    Braun, D.C.6    Choi, S.H.7    Blumberg, P.M.8    Garfield, S.H.9    Stone, J.C.10
  • 27
    • 0347993052 scopus 로고    scopus 로고
    • RasGRP1 represents a novel non-protein kinase C phorbol ester signaling pathway in mouse epidermal keratinocytes
    • Rambaratsingh RA, Stone JC, Blumberg PM, and Lorenzo PS (2003) RasGRP1 represents a novel non-protein kinase C phorbol ester signaling pathway in mouse epidermal keratinocytes. J Biol Chem 278:52792-52801.
    • (2003) J Biol Chem , vol.278 , pp. 52792-52801
    • Rambaratsingh, R.A.1    Stone, J.C.2    Blumberg, P.M.3    Lorenzo, P.S.4
  • 29
    • 0032538564 scopus 로고    scopus 로고
    • Differential downstream functions of protein kinase Cη and -θ in EL4 mouse thymoma cells
    • Resnick MS, Kang BS, Luu D, Wickham JT, Sando JJ, and Hahn CS (1998) Differential downstream functions of protein kinase Cη and -θ in EL4 mouse thymoma cells. J Biol Chem 273:27654-27661.
    • (1998) J Biol Chem , vol.273 , pp. 27654-27661
    • Resnick, M.S.1    Kang, B.S.2    Luu, D.3    Wickham, J.T.4    Sando, J.J.5    Hahn, C.S.6
  • 30
    • 0030954564 scopus 로고    scopus 로고
    • Selective up-regulation of protein kinase C eta in phorbol ester-sensitive versus -resistant EL4 mouse thymoma cells
    • Resnick MS, Luo X, Vinton EG, and Sando JJ (1997) Selective up-regulation of protein kinase C eta in phorbol ester-sensitive versus -resistant EL4 mouse thymoma cells. Cancer Res 57:2209-2215.
    • (1997) Cancer Res , vol.57 , pp. 2209-2215
    • Resnick, M.S.1    Luo, X.2    Vinton, E.G.3    Sando, J.J.4
  • 32
    • 0028962881 scopus 로고
    • Rapid tyrosine phosphorylation of an 85,000 M(r) protein after phorbol ester stimulation of EL4 thymoma cells
    • Richardson AF and Sando JJ (1995) Rapid tyrosine phosphorylation of an 85,000 M(r) protein after phorbol ester stimulation of EL4 thymoma cells. Cell Signal 7:17-30.
    • (1995) Cell Signal , vol.7 , pp. 17-30
    • Richardson, A.F.1    Sando, J.J.2
  • 34
    • 18944383647 scopus 로고    scopus 로고
    • A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells
    • Roose JP, Mollenauer M, Gupta VA, Stone J, and Weiss A (2005) A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. Mol Cell Biol 25:4426-4441.
    • (2005) Mol Cell Biol , vol.25 , pp. 4426-4441
    • Roose, J.P.1    Mollenauer, M.2    Gupta, V.A.3    Stone, J.4    Weiss, A.5
  • 35
    • 0020037362 scopus 로고
    • Identification of phorbol ester receptors in T-cell growth factor-producing and -nonproducing EL4 mouse thymoma cells
    • Sando JJ, Hilfiker ML, Piacentini MJ, and Laufer TM (1982) Identification of phorbol ester receptors in T-cell growth factor-producing and -nonproducing EL4 mouse thymoma cells. Canc Res 42:1676-1680.
    • (1982) Canc Res , vol.42 , pp. 1676-1680
    • Sando, J.J.1    Hilfiker, M.L.2    Piacentini, M.J.3    Laufer, T.M.4
  • 36
  • 37
    • 0031427717 scopus 로고    scopus 로고
    • Effects of protein kinase C activators on phorbol ester-sensitive and -resistant EL4 thymoma cells
    • Sansbury HM, Wisehart-Johnson AE, Qi C, Fulwood S, and Meier KE (1997) Effects of protein kinase C activators on phorbol ester-sensitive and -resistant EL4 thymoma cells. Carcinogenesis 18:1817-1824.
    • (1997) Carcinogenesis , vol.18 , pp. 1817-1824
    • Sansbury, H.M.1    Wisehart-Johnson, A.E.2    Qi, C.3    Fulwood, S.4    Meier, K.E.5
  • 40
    • 33645472651 scopus 로고    scopus 로고
    • Differential effects of bryostatin 1 and 12-O-tetradecanoylphorbol-13-acetate on the regulation and activation of Ras-GRP1 in mouse epidermal keratinocytes
    • Tuthill MC, Oki CE, and Lorenzo PS (2006) Differential effects of bryostatin 1 and 12-O-tetradecanoylphorbol-13-acetate on the regulation and activation of Ras-GRP1 in mouse epidermal keratinocytes Mol Canc Ther 5:602-610.
    • (2006) Mol Canc Ther , vol.5 , pp. 602-610
    • Tuthill, M.C.1    Oki, C.E.2    Lorenzo, P.S.3
  • 41
    • 0037459321 scopus 로고    scopus 로고
    • Signaling life and death in the thymus: Timing is everything
    • Werlen G, Hausmann B, Naeher D, and Palmer E (2003) Signaling life and death in the thymus: timing is everything. Science (Wash DC) 299:1859-1862.
    • (2003) Science (Wash DC) , vol.299 , pp. 1859-1862
    • Werlen, G.1    Hausmann, B.2    Naeher, D.3    Palmer, E.4
  • 42
    • 0037067713 scopus 로고    scopus 로고
    • RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function
    • Yang Y, Li L, Wong GW, Krilis SA, Madhusadhan MS, Sali A, and Stevens RL (2002) RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function. J Biol Chem 277:25756-25774.
    • (2002) J Biol Chem , vol.277 , pp. 25756-25774
    • Yang, Y.1    Li, L.2    Wong, G.W.3    Krilis, S.A.4    Madhusadhan, M.S.5    Sali, A.6    Stevens, R.L.7
  • 43
    • 18244409902 scopus 로고    scopus 로고
    • Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells
    • Zheng Y, Liu H, Coughlin J, Zheng J, Li L, and Stone JC (2005) Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells. Blood 105:3648-3654.
    • (2005) Blood , vol.105 , pp. 3648-3654
    • Zheng, Y.1    Liu, H.2    Coughlin, J.3    Zheng, J.4    Li, L.5    Stone, J.C.6


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