-
1
-
-
33745879486
-
Contribution of human embryonic stem cells to mouse blastocysts
-
James, D., Noggle, S.A., Swigut, T. and Brivanlou, A.H. Contribution of human embryonic stem cells to mouse blastocysts. Dev. Biol. 2006, 295: 90-102.
-
(2006)
Dev. Biol.
, vol.295
, pp. 90-102
-
-
James, D.1
Noggle, S.A.2
Swigut, T.3
Brivanlou, A.H.4
-
2
-
-
0347135824
-
Embryonic stem cells in drug discovery
-
McNeish, J. Embryonic stem cells in drug discovery. Nat. Rev. Drug Disc. 2004, 3: 70-80.
-
(2004)
Nat. Rev. Drug Disc.
, vol.3
, pp. 70-80
-
-
McNeish, J.1
-
3
-
-
27944509526
-
ES cell technology: An introduction to genetic manipulation, differentiation and therapeutic cloning
-
Hook, L., O'Brien, C. and Allsopp, T. ES cell technology: An introduction to genetic manipulation, differentiation and therapeutic cloning. Adv. Drug Del. Rev. 2005, 57:1904-1917.
-
(2005)
Adv. Drug Del. Rev.
, vol.57
, pp. 1904-1917
-
-
Hook, L.1
O'Brien, C.2
Allsop, T.3
-
4
-
-
20544474686
-
Adult stem cell therapy beyond haemopoietic stem cell transplantation? An update
-
Hows, J. Adult stem cell therapy beyond haemopoietic stem cell transplantation? An update. Transpl. Immunol. 2005, 14: 221-223.
-
(2005)
Transpl. Immunol.
, vol.14
, pp. 221-223
-
-
Hows, J.1
-
5
-
-
22944488895
-
Genetic manipulation of human embryonic stem cells: A system to study early human development and potential therapeutic applications
-
Mendez, P., Wang, L. and Bhatia, M. Genetic manipulation of human embryonic stem cells: A system to study early human development and potential therapeutic applications. Curr. Gene Ther. 2005, 5: 1-11.
-
(2005)
Curr. Gene Ther.
, vol.5
, pp. 1-11
-
-
Mendez, P.1
Wang, L.2
Bhatia, M.3
-
6
-
-
15944400651
-
Towards safe, non-viral therapeutic gene expression in humans
-
Glover, D.J., Lipps, H.J. and Jans, D.A. Towards safe, non-viral therapeutic gene expression in humans. Nat. Rev. Genet. 2005, 4, 299-310.
-
(2005)
Nat. Rev. Genet.
, vol.4
, pp. 299-310
-
-
Glover, D.J.1
Lipps, H.J.2
Jans, D.A.3
-
7
-
-
0038745599
-
Progress and problems with the use of viral vectors for gene therapy
-
Thomas, C.E., Ehrhardt, A. and Kay, M.A. Progress and problems with the use of viral vectors for gene therapy. Nat. Rev. Genet. 2003, 4: 346-358.
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 346-358
-
-
Thomas, C.E.1
Ehrhardt, A.2
Kay, M.A.3
-
8
-
-
33746382212
-
Mechanisms of site-specific recombination
-
Grindley, N.D.F., Whiteson, K.L., Rice, P.A. Mechanisms of site-specific recombination. Annu. Rev. Biochem. 2006, 75: 567-605.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 567-605
-
-
Grindley, N.D.F.1
Whiteson, K.L.2
Rice, P.A.3
-
9
-
-
23844447665
-
Comparative analysis of sequence-specific DNA recombgination systems in human embryonic stem cells
-
Tan, S.M. and Dröge, P. Comparative analysis of sequence-specific DNA recombgination systems in human embryonic stem cells. Stem Cells 2005, 23: 868-873.
-
(2005)
Stem Cells
, vol.23
, pp. 868-873
-
-
Tan, S.M.1
Dröge, P.2
-
10
-
-
0346503889
-
Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice
-
Branda, C.S. and Dymecki, S.M. Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice. Dev. Cell 2004, 1: 7-28.
-
(2004)
Dev. Cell
, vol.1
, pp. 7-28
-
-
Branda, C.S.1
Dymecki, S.M.2
-
11
-
-
33744527608
-
Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase
-
Nolden, L., Edenhofer, F., Haupt, S., Koch, P., Wunderlich, F.T., Siemen, H. And Brüstle, O. Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase. Nat. Methods 2006, 3: 461-467.
-
(2006)
Nat. Methods
, vol.3
, pp. 461-467
-
-
Nolden, L.1
Edenhofer, F.2
Haupt, S.3
Koch, P.4
Wunderlich, F.T.5
Siemen, H.6
Brüstle, O.7
-
12
-
-
0030809406
-
Targeted integration of DNA using mutant lox sites in embryonic stem cells
-
Araki, K., Araki, M. and Yarnamura, K. Targeted integration of DNA using mutant lox sites in embryonic stem cells. Nucleic Acids Res. 1997, 25: 868-872.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 868-872
-
-
Araki, K.1
Araki, M.2
Yarnamura, K.3
-
13
-
-
33746489506
-
RMCE-ASAP: A gene targeting method for ES and somatic cells to accelerate phenotype analyses
-
Toledo, F., Liu, C.W., Lee, C.J. and Wahl, G.M. RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses. Nucleic Acids Res. 2006, 34:e92.
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Toledo, F.1
Liu, C.W.2
Lee, C.J.3
Wahl, G.M.4
-
14
-
-
33745096164
-
A high-throughput screen identifying sequence and promiscuity characteristics of the loxP spacer region in Cre-mediated recombination
-
Missirlis, P.I., Smailus, D.E. and Holt, R.A. A high-throughput screen identifying sequence and promiscuity characteristics of the loxP spacer region in Cre-mediated recombination. BMC Genomics 2006, 7: 73.
-
(2006)
BMC Genomics
, vol.7
, pp. 73
-
-
Missirlis, P.I.1
Smailus, D.E.2
Holt, R.A.3
-
15
-
-
0037337299
-
Site-specific cassette exchange and germline transmission with mouse ES cells expressing φC31 integrase
-
Belteki, G., Gertsenstein, M., Ow, D.W. and Nagy, A. Site-specific cassette exchange and germline transmission with mouse ES cells expressing φC31 integrase. Nat. Biotech. 2003, 21: 321-324.
-
(2003)
Nat. Biotech.
, vol.21
, pp. 321-324
-
-
Belteki, G.1
Gertsenstein, M.2
Ow, D.W.3
Nagy, A.4
-
16
-
-
1642565399
-
Switching the polarity of a bacteriophage integration system
-
Smith, M.C. and Till, R. Switching the polarity of a bacteriophage integration system. Mol. Microbiol. 2004, 51: 1719-1728.
-
(2004)
Mol. Microbiol.
, vol.51
, pp. 1719-1728
-
-
Smith, M.C.1
Till, R.2
-
17
-
-
1542397137
-
Phage integrases: Biology and applications
-
Groth, A.C. and Calos, M.P. Phage integrases: biology and applications. J. Mol. Biol. 2004, 335: 667-678.
-
(2004)
J. Mol. Biol.
, vol.335
, pp. 667-678
-
-
Groth, A.C.1
Calos, M.P.2
-
18
-
-
33845671438
-
Creation of an engineered human embryonal carcinoma cell line with site-specific integration
-
Toronto, Ontario, Canada
-
Thyagarajan, B., Lakshmipathy, U. and Chestnut, J. Creation of an engineered human embryonal carcinoma cell line with site-specific integration. 4th ISSCR Annual Meeting, Toronto, Ontario, Canada, 2006, pp. 47.
-
(2006)
4th ISSCR Annual Meeting
, pp. 47
-
-
Thyagarajan, B.1
Lakshmipathy, U.2
Chestnut, J.3
-
19
-
-
33644767178
-
Integration specificity ofphage phiC31 integrase in the human genome
-
Chalberg, T.W., Portlock, J.L., Olivares, E.C., Thyagarajan, B., Kirby, P.J., Hillman, R.T., Hoelters, J. and Calos, M.P. Integration specificity ofphage phiC31 integrase in the human genome. J. Mol. Biol. 2006, 357: 28-48.
-
(2006)
J. Mol. Biol.
, vol.357
, pp. 28-48
-
-
Chalberg, T.W.1
Portlock, J.L.2
Olivares, E.C.3
Thyagarajan, B.4
Kirby, P.J.5
Hillman, R.T.6
Hoelters, J.7
Calos, M.P.8
-
20
-
-
0347634456
-
Gene therapy insertional mutagenesis insights
-
Dave, U.P., Jenkins, N.A. and Copeland, N.G. Gene therapy insertional mutagenesis insights. Science 2004, 303: 333.
-
(2004)
Science
, vol.303
, pp. 333
-
-
Dave, U.P.1
Jenkins, N.A.2
Copeland, N.G.3
-
21
-
-
25144432005
-
Site-specific integration with φC31 integrase for prolonged expression of therapeutic genes
-
Ginsburg, D.S. and Calos, M.P. Site-specific integration with φC31 integrase for prolonged expression of therapeutic genes. Adv. Genetics 2005, 54: 179-187.
-
(2005)
Adv. Genetics
, vol.54
, pp. 179-187
-
-
Ginsburg, D.S.1
Calos, M.P.2
-
22
-
-
4644292834
-
Nucleofection of muscle-derived stem cells and myoblasts with φC31 integrasc: Stable expression of a full-length-dystrophin fusion gene by human myoblasts
-
Quenneville, S.P., Chapdelaine, P., Rousseau, J., Beaulieu, J., Caron, N.J., Skuk, D., Mills, P., Olivares, E.C., Calos, M.P. and Tremblay, J.P. Nucleofection of muscle-derived stem cells and myoblasts with φC31 integrasc: stable expression of a full-length-dystrophin fusion gene by human myoblasts. Mol. Therapy 2004, 10: 679-687.
-
(2004)
Mol. Therapy
, vol.10
, pp. 679-687
-
-
Quenneville, S.P.1
Chapdelaine, P.2
Rousseau, J.3
Beaulieu, J.4
Caron, N.J.5
Skuk, D.6
Mills, P.7
Olivares, E.C.8
Calos, M.P.9
Tremblay, J.P.10
-
23
-
-
0036606856
-
Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: Activity comparison with Cre and FLPe recombinase in mammalian cells
-
Andreas, S., Schwenk, F., Kuter-Luks, B., Faust, N. and Kuhn, R. Enhanced efficiency through nuclear localization signal fusion on phage PhiC31-integrase: Activity comparison with Cre and FLPe recombinase in mammalian cells. Nucleic Acids Res. 2002, 30: 2299-2306.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 2299-2306
-
-
Andreas, S.1
Schwenk, F.2
Kuter-Luks, B.3
Faust, N.4
Kuhn, R.5
-
24
-
-
0343415768
-
Mammalian genomes contain active recombinase recognition sites
-
Thyagarajan, B., Guimaraes, M.J., Groth, A.C. and Calos, M.P. Mammalian genomes contain active recombinase recognition sites. Gene 2000, 244: 47-54.
-
(2000)
Gene
, vol.244
, pp. 47-54
-
-
Thyagarajan, B.1
Guimaraes, M.J.2
Groth, A.C.3
Calos, M.P.4
-
25
-
-
0034610394
-
Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermadis
-
Schmidt, E.E., Taylor, D.S., Prigge, J.R., Barnett, S. and Capecchi, M. Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermadis. Proc. Natl. Acad. Sci. USA 2000, 97: 13702-13707.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13702-13707
-
-
Schmidt, E.E.1
Taylor, D.S.2
Prigge, J.R.3
Barnett, S.4
Capecchi, M.5
-
26
-
-
0035979247
-
Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells
-
Loonstra, A., Vooijs, M., Beverloo, H.B., Allak, B.A., van Drunen, E., Kanaar, R. and Berns, A. Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells. Proc. Natl. Acad. Sci. USA 2001, 98: 9209-9214.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9209-9214
-
-
Loonstra, A.1
Vooijs, M.2
Beverloo, H.B.3
Allak, B.A.4
van Drunen, E.5
Kanaar, R.6
Berns, A.7
-
27
-
-
33746124221
-
φC31 integrase induces chromosomal aberrations in primary human fibroblasts
-
Liu, J., Nielsen, K. and Jensen, T.G. φC31 integrase induces chromosomal aberrations in primary human fibroblasts. Gene Therapy 2006, 13: 1188-1190.
-
(2006)
Gene Therapy
, vol.13
, pp. 1188-1190
-
-
Liu, J.1
Nielsen, K.2
Jensen, T.G.3
-
28
-
-
19544371373
-
Gene targeting in mice: Functional analysis of the mammalian genome for the twenty-first century
-
Capecchi, M.R. Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century. Nat. Rev. Genet. 2005, 6: 507-512.
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 507-512
-
-
Capecchi, M.R.1
-
29
-
-
33745630326
-
Mouse genetics. A mouse for every gene
-
Grimm, D. Mouse genetics. A mouse for every gene. Science, 312: 1862-1866.
-
Science
, vol.312
, pp. 1862-1866
-
-
Grimm, D.1
-
30
-
-
0037336820
-
Homologous recombination in human embryonic stem cells
-
Zwaka, T.P. and Thomson, J.A. Homologous recombination in human embryonic stem cells. Nat. Biotech. 2003, 21: 319-321.
-
(2003)
Nat. Biotech.
, vol.21
, pp. 319-321
-
-
Zwaka, T.P.1
Thomson, J.A.2
-
31
-
-
3543030995
-
Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells
-
Urbach, A., Schuldiner, M. and Benvenisty, N. Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells. Stem Cells 2004, 22: 635-641.
-
(2004)
Stem Cells
, vol.22
, pp. 635-641
-
-
Urbach, A.1
Schuldiner, M.2
Benvenisty, N.3
-
32
-
-
27744530147
-
Zinc finger nucleases: Custom-designed molecular scissors for genome engineering of plant and mammalian cells
-
Durai, S., Mani, M., Kandavelou, K., Wu, J., Porteus, M.H. and Chandrasegaran, S. Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells. Nucleic Acids Res. 2005, 33: 5978-5990.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 5978-5990
-
-
Durai, S.1
Mani, M.2
Kandavelou, K.3
Wu, J.4
Porteus, M.H.5
Chandrasegaran, S.6
-
33
-
-
18944373328
-
Highly efficient endogenous human gene conversion using zinc-finger nucleases
-
Urnov, F.D., Miller, J.C., Lee, Y.L., Beausejour, C.M., Rock, J.M., Augustus, S., Jamieson, A.C., Porteus, M.H., Gregory, P.D. and Holmes, M.C. Highly efficient endogenous human gene conversion using zinc-finger nucleases. Nature 2005, 435: 646-651.
-
(2005)
Nature
, vol.435
, pp. 646-651
-
-
Urnov, F.D.1
Miller, J.C.2
Lee, Y.L.3
Beausejour, C.M.4
Rock, J.M.5
Augustus, S.6
Jamieson, A.C.7
Porteus, M.H.8
Gregory, P.D.9
Holmes, M.C.10
-
34
-
-
10744222737
-
Gene targeting in stem cells from individuals with osteogenesis imperfecta
-
Chamberlain, J.R., Schwarze, U., Wang, P-R, Hirata, R.K., Hankenson, K.D., Pace, J.M., Underwood, R.A., Song, K.M., Sussman, M., Byers, P.H. and Russell, D.W. Gene targeting in stem cells from individuals with osteogenesis imperfecta. Science 2004, 303: 1198-1201.
-
(2004)
Science
, vol.303
, pp. 1198-1201
-
-
Chamberlain, J.R.1
Schwarze, U.2
Wang, P.-R.3
Hirata, R.K.4
Hankenson, K.D.5
Pace, J.M.6
Underwood, R.A.7
Song, K.M.8
Sussman, M.9
Byers, P.H.10
Russell, D.W.11
-
35
-
-
0036209708
-
Integration site selection by lentiviruses: Biology and possible control
-
Bushman, F.D. Integration site selection by lentiviruses: biology and possible control. Curr. Top. Microb. Immunol. 2002, 261: 165-77.
-
(2002)
Curr. Top. Microb. Immunol.
, vol.261
, pp. 165-177
-
-
Bushman, F.D.1
|