Reduced cellular transport and activation of fluoropyrimidine nucleosides and resistance in human lymphocytic cell lines selected for arabinosylcytosine resistance

Biochemical Pharmacology

Volumn 61, Issue 1, 2001, Pages 39-47

  Agarwal, Ram P ^a   Han, Tieran ^a   Fernandez, Marilyn ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Arabinosylcytosine; Arabinosylcytosine resistance; Cross resistance; Fluorodeox yuridine; Fluoropyrimidines; Fluorouracil; Fluorouridine; H9 cells; HL60 cells; Human lymphocytic cell lines; Nucleoside transport; Promyelocytic cell lines

Indexed keywords

CYTARABINE; FLOXURIDINE; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; FLUOROURIDINE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; NITROBENZYLTHIOINOSINE; NUCLEOSIDE; THYMIDINE KINASE; THYMIDYLATE SYNTHASE; URIDINE KINASE;

ANIMAL CELL; ARTICLE; CELL TRANSPORT; CONTROLLED STUDY; CROSS RESISTANCE; DRUG BINDING SITE; ENZYME ACTIVITY; GENE EXPRESSION; LYMPHOID CELL LINE; MOUSE; NONHUMAN; NUCLEOSIDE TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIMETABOLITES, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; CELL LINE; CYTARABINE; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FLOXURIDINE; FLUOROURACIL; HL-60 CELLS; HUMANS;

EID: 0035184489     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00530-X     Document Type: Article

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