5-Fluorouracil prevents lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells by inhibiting Akt-dependent nuclear factor-κB activation

Cancer Chemotherapy and Pharmacology

Volumn 59, Issue 2, 2007, Pages 227-233

  Islam, Shamima ^a   Hassan, Ferdaus ^a   Tumurkhuu, Gantsetseg ^a   Ito, Hiroyasu ^a   Koide, Naoki ^a   Mori, Isamu ^a   Yoshida, Tomoaki ^a   Yokochi, Takashi ^a  

^a AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

5 FU; Akt; iNOS; LPS; NF B; NO

Indexed keywords

FLUOROURACIL; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CELL LINE; CELL NUCLEUS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOROURACIL; LIPOPOLYSACCHARIDES; LUCIFERASES; MACROPHAGES; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

EID: 33845371107     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-006-0261-2     Document Type: Article

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