Glucocorticoid receptor mediated repression of human insulin gene expression is regulated by PGC-1α

Biochemical and Biophysical Research Communications

Volumn 352, Issue 3, 2007, Pages 716-721

  Jang, Won Gu ^a   Kim, Eun Jung ^b   Park, Keun Gyu ^c   Park, Yong Bok ^a   Choi, Hueng Sik ^d   Kim, Hye Jin ^b   Kim, Yong Deuk ^d   Kim, Kyung Sup ^e   Lee, Ki Up ^f   Lee, In Kyu ^b  

^a Kyungpook National University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c Keimyung University School of Medicine   (South Korea)

^d Chonnam National University   (South Korea)

^e Yonsei University College of Medicine   (South Korea)

^f University of Ulsan College of Medicine   (South Korea)

Author keywords

GR; INS 1 cells; Insulin promoter; NRE; Palindromic region; PGC 1

Indexed keywords

GLUCOCORTICOID RECEPTOR; HUMAN INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE LOCATION; GENE REPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; RECEPTOR BINDING;

ANIMALS; BINDING SITES; CELL LINE; DOWN-REGULATION; GENE EXPRESSION REGULATION; INSULIN; INSULIN-SECRETING CELLS; PROTEIN BINDING; RATS; RECEPTORS, GLUCOCORTICOID; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS;

EID: 33845324883     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.11.074     Document Type: Article

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