Delivery of 125I-cobrotoxin after intranasal administration to the brain: A microdialysis study in freely moving rats

International Journal of Pharmaceutics

Volumn 328, Issue 2, 2007, Pages 161-167

  Li, Fanzhu ^a   Feng, Jian ^a   Cheng, Qiaoyuan ^a   Zhu, Wenjing ^a   Jin, Yuji ^b  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Cobrotoxin; Intranasal administration; Microdialysis; Nose brain pathway; Rats

Indexed keywords

BORNEOL; COBROTOXIN; IODINE 125; MENTHOL; RADIOACTIVE IODINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BRAIN; CENTRAL NERVOUS SYSTEM; CEREBELLUM NUCLEUS; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG TRANSPORT; ISOTOPE LABELING; MALE; MICRODIALYSIS; MOLECULAR WEIGHT; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL; RADIOACTIVITY; RAT; ANIMAL; COMPARATIVE STUDY; INTRANASAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; SPRAGUE DAWLEY RAT;

ADMINISTRATION, INTRANASAL; ANIMALS; CEREBELLAR NUCLEI; COBRA NEUROTOXINS; INJECTIONS, INTRAVENOUS; IODINE RADIOISOTOPES; MALE; MICRODIALYSIS; OLFACTORY BULB; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33845316415     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.08.011     Document Type: Article

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