Pharmacokinetic behavior in plasma, cerebrospinal fluid and cerebral cortex after intranasal administration of hydrochloride meptazinol

Life Sciences

Volumn 77, Issue 20, 2005, Pages 2574-2583

  Shi, Zhenqi ^a   Zhang, Qizhi ^a   Jiang, Xinguo ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Cerebrospinal fluid; Cortex; Intranasal administration; Meptazinol hydrochloride; Olfactory pathway; Rat

Indexed keywords

MEPTAZINOL;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BRAIN; BRAIN CORTEX; CEREBROSPINAL FLUID; DIALYSATE; DRUG ABSORPTION; DRUG ADMINISTRATION ROUTE; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MEASUREMENT; MICRODIALYSIS; NONHUMAN; NOSE CAVITY; OLFACTORY EPITHELIUM; PLASMA; RAT; SAMPLE; SAMPLING; SYSTEMIC CIRCULATION;

ADMINISTRATION, INTRANASAL; ANIMALS; AREA UNDER CURVE; CEREBRAL CORTEX; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; INJECTIONS, INTRAVENOUS; MALE; MEPTAZINOL; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

EID: 24044469044     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.02.025     Document Type: Article

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