Progesterone receptor isoforms A and B: Temporal and spatial differences in expression during murine mammary gland development

Endocrinology

Volumn 146, Issue 8, 2005, Pages 3577-3588

  Aupperlee, Mark D ^a   Smith, Kyle T ^a   Kariagina, Anastasia ^a   Haslam, Sandra Z ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CYCLIN D1; PROGESTERONE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; GENE FUNCTION; GENE LOCATION; GENETIC ENGINEERING; MAMMARY GLAND; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BROMODEOXYURIDINE; CYCLIN D1; FEMALE; FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MAMMARY GLANDS, ANIMAL; MICE; MICE, INBRED BALB C; PREGNANCY; RECEPTORS, PROGESTERONE;

EID: 23044500236     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2005-0346     Document Type: Article

References (36)

1. Haslam SZ, Osuch JR, Raafat AM, Hofseth LJ 2002 Postmenopausal hormone replacement therapy: effects on normal mammary gland in humans and in a mouse postmenopausal model. J Mammary Gland Biol Neoplasia 7:93-105
2. Cline JM, Soderqvist G, von Schoultz E, Skoog L, von Schoultz B 1996 Effects of hormone replacement therapy on the mammary gland of surgically postmenopausal cynomolgus macaques. Am J Obstet Gynecol 174:93-100
3. Fendrick JL, Raafat AM, Haslam SZ 1998 Mammary gland growth and development from the postnatal period to postmenopause: ovarian steroid receptor ontogeny and regulation in the mouse. J Mammary Gland Biol Neoplasia 3:7-22
4. Hofseth LJ, Raafat AM, Osuch JR, Pathak DR, Slomski CA, Haslam SZ 1999 Hormone replacement therapy with estrogen or estrogen plus medroxyprogesterone acetate is associated with increased epithelial proliferation in the normal postmenopausal breast. J Clin Endocrinol Metab 84:4559-4565
5. Magnusson C, Persson I, Adami HO 2000 More about: effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin. J Natl Cancer Inst 92:1183-1184
6. Ross RK, Paganini-Hill A, Wan PC, Pike MC 2000 Effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin. J Natl Cancer Inst 92:328-332
7. Schairer C, Lubin J, Troisi R, Sturgeon S, Brinton L, Hoover R 2000 Menopausal estrogen and estrogen-progestin replacement therapy and breast cancer risk. JAMA 283:485-491
8. Writing Group for the Women's Health Initiative Investigators 2002 Risks and benefits of estrogen plus progestin in healthy postmenopausal women. JAMA 288:321-333
9. Lydon JP, Sivaraman L, Conneely OM 2000 A reappraisal of progesterone action in the mammary gland. J Mammary Gland Biol Neoplasia 5:325-338
10. Kastner P, Krust A, Turcotte B, Stropp U, Tora L, Gronemeyer H, Chambon P 1990 Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J 9:1603-1614
11. Kraus WL, Montano MM, Katzenellenbogen BS 1993 Cloning of the rat progesterone receptor gene 5′-region and identification of two functionally distinct promoters. Mol Endocrinol 7:1603-1616
12. Shyamala G, Yang X, Silberstein G, Barcellos-Hoff MH, Dale E 1998 Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands. Proc Natl Acad Sci USA 95:696-701
13. Shyamala G, Yang X, Cardiff RD, Dale E 2000 Impact of progesterone receptor on cell-fate decisions during mammary gland development. Proc Natl Acad Sci USA 97:3044-3049
14. Lydon JP, DeMayo FJ, Funk CR, Mani SK, Hughes AR, Montgomery Jr CA, Shyamala G, Conneely OM, O'Malley BW 1995 Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev 9:2266-2278
15. Mulac-Jericevic B, Mullinax RA, DeMayo FJ, Lydon JP, Conneely OM 2000 Subgroup of reproductive functions of progesterone mediated by progesterone receptor-B isoform. Science 289:1751-1754
16. Mulac-Jericevic B, Lydon JP, DeMayo FJ, Conneely OM 2003 Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci USA 100:9744-9749
17. Takimoto GS, Tung L, Abdel-Hafiz H, Abel MG, Sartorius CA, Richer JK, Jacobsen BM, Bain DL, Horwitz KB 2003 Functional properties of the N-terminal region of progesterone receptors and their mechanistic relationship to structure. J Steroid Biochem Mol Biol 85:209-219
18. Silberstein GB, Van Horn K, Shyamala G, Daniel CW 1996 Progesterone receptors in the mouse mammary duct: distribution and developmental regulation. Cell Growth Differ 7:945-952
19. Atwood CS, Hovey RC, Glover JP, Chepko G, Ginsburg E, Robison WG, Vonderhaar BK 2000 Progesterone induces side-branching of the ductal epithelium in the mammary glands of peripubertal mice. J Endocrinol 167:39-52
20. Mote PA, Johnston JF, Manninen T, Tuohimaa P, Clarke CL 2001 Detection of progesterone receptor forms A and B by immunohistochemical analysis. J Clin Pathol 54:624-630
21. Gava N, Clarke CL, Byth K, Arnett-Mansfield RL, deFazio A 2004 Expression of progesterone receptors A and B in the mouse ovary during the estrous cycle. Endocrinology 145:3487-3494
22. Haslam SZ 1988 Progesterone effects on deoxyribonucleic acid synthesis in normal mouse mammary glands. Endocrinology 122:464-470
23. Haslam SZ 1989 The ontogeny of mouse mammary gland responsiveness to ovarian steroid hormones. Endocrinology 125:2766-2772
24. Haslam SZ, Counterman LJ, St. John AR 1993 Hormonal basis for acquisition of estrogen-dependent progesterone receptors in the normal mouse mammary gland. Steroid Biochem (Life Sci Adv) 12:27-34
25. Mote PA, Balleine RL, McGowan EM, Clarke CL 1999 Colocalization of progesterone receptors A and B by dual immunofluorescent histochemistry in human endometrium during the menstrual cycle. J Clin Endocrinol Metab 84:2963-2971
26. Mote PA, Bartow S, Tran N, Clarke CL 2002 Loss of co-ordinate expression of progesterone receptors A and B is an early event in breast carcinogenesis. Breast Cancer Res Treat 72:163-172
27. Haslam SZ, Levely ML 1985 Estrogen responsiveness of normal mouse mammary cells in primary cell culture: association of mammary fibroblasts with estrogenic regulation of progesterone receptors. Endocrinology 116:1835-1844
28. Shyamala G, Schneider W, Schott D 1990 Developmental regulation of murine mammary progesterone receptor gene expression. Endocrinology 126:2882-2889
29. Sicinski P, Weinberg RA 1997 A specific role for cyclin D1 in mammary gland development. J Mammary Gland Biol Neoplasia 2:335-342
30. Sunil N, Bennett JM, Haslam SZ 2002 Hepatocyte growth factor is required for progestin-induced epithelial cell proliferation and alveolar-like morphogenesis in serum-free culture of normal mammary epithelial cells. Endocrinology 143:2953-2960
31. Bocchinfuso WP, Korach KS 1997 Mammary gland development and tumorigenesis in estrogen receptor knockout mice. J Mammary Gland Biol Neoplasia 2:323-334
32. Hovey RC, Trott JF, Vonderhaar BK 2002 Establishing a framework for the functional mammary gland: from endocrinology to morphology. J Mammary Gland Biol Neoplasia 7:17-38
33. Seagroves TN, Lydon JP, Hovey RC, Vonderhaar BK, Rosen JM 2000 C/EBPβ (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development. Mol Endocrinol 14:359-368
34. Haslam SZ, Shyamala G 1979 Effect of oestradiol on progesterone receptors in normal mammary glands and its relationship with lactation. Biochem J 182:127-131
35. Medina D 2004 Breast cancer: the protective effect of pregnancy. Clin Cancer Res 10:380S-384S
36. Jacobsen BM, Schittone SA, Richer JK, Horwitz KB 2005 Progesterone-independent effects of human progesterone receptors (PRs) in estrogen receptorpositive breast cancer: PR isoform-specific gene regulation and tumor biology. Mol Endocrinol 19:574-587