A prospective on stem cell research

Seminars in Reproductive Medicine

Volumn 24, Issue 5, 2006, Pages 289-297

  Gokhale, Paul J ^a   Andrews, Peter W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Adult; Differentiation; Embryonic; Self renewal; Stem cells

Indexed keywords

MEMBRANE ANTIGEN; TRANSCRIPTION FACTOR;

ARTIFACT; BIOLOGY; CARCINOGENESIS; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; CELL RENEWAL; CELL TYPE; CONTROL SYSTEM; EMBRYONIC STEM CELL; GENE MUTATION; HUMAN; MEDICAL RESEARCH; MULTIPOTENT STEM CELL; REVIEW; RNA SYNTHESIS; SPECIES DIFFERENCE; STEM CELL;

ADAPTATION, BIOLOGICAL; ADULT STEM CELLS; ANIMALS; BIOLOGICAL MARKERS; CELL PROLIFERATION; CELLS, CULTURED; DISEASE PROGRESSION; EMBRYONIC STEM CELLS; HUMANS; MULTIPOTENT STEM CELLS; NEOPLASMS; RESEARCH; STEM CELLS;

EID: 33845313297     PISSN: 15268004     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-952151     Document Type: Review

References (105)

1. Maximow A. Der lymphozyt als gemeinsame stammzelle der verschiedenen blutelemente in der embryonalen entwicklung und im postfetalen leben der saugetiere. Folia Haematologica VIII 1909;8:125-134
2. Osgood EE. A unifying concept of the etiology of the leukemias, lymphomas, and cancers. J Natl Cancer Inst 1957;18(2):155-166
3. Osgood EE. Blood cell survival in tissue cultures. Ann NY Acad Sci 1959;77:777-796
4. McCulloch EA, Till JE. The radiation sensitivity of normal mouse bone marrow cells, determined by quantitative marrow transplantation into irradiated mice. Radiat Res 1960;13:115-125
5. Till JE, Mc CE. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res 1961;14:213-222
6. Becker AJ, Mc CE, Till JE. Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature 1963;197:452-454
7. Siminovitch L, McCulloch EA, Till JE. The distribution of colony-forming cells among spleen colonies. J Cell Physiol 1963;62:327-336
8. Till JE, McCulloch EA, Siminovitch L. A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells. Proc Natl Acad Sci USA 1964;51:29-36
9. Lin H, Spradling AC. Fusome asymmetry and oocyte determination in Drosophila. Dev Genet 1995;16(1):6-12
10. Ivanova NB, Dimos JT, Schaniel C, Hackney JA, Moore KA, Lemischka IR. A stem cell molecular signature. Science 2002;298(5593):601-604
11. Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science 2002;298(5593):597-600
12. Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 1981;78(12):7634-7638
13. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature 1981;292(5819):154-156
14. Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998;282(5391):1145-1147
15. Andrews PW. From teratocarcinomas to embryonic stem cells. Philos Trans R Soc Lond B Biol Sci 2002;357(1420):405-417
16. Finch BW, Ephrussi B. Retention of multiple developmental potentialities by cells of a mouse testicular teratocarcinoma during prolonged culture in vitro and their extinction upon hybridization with cells of permanent lines. Proc Natl Acad Sci USA 1967;57(3):615-621
17. Martin GR, Evans MJ. Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro. Proc Natl Acad Sci USA 1975;72(4):1441-1445
18. Jakob H, Boon T, Gaillard J, Nicolas J, Jacob F. Teratocarcinoma of the mouse: isolation, culture and properties of pluripotential cells. Ann Microbiol (Paris) 1973;124(3):269-282
19. Evans MJ. The isolation and properties of a clonal tissue culture strain of pluripotent mouse teratoma cells. J Embryol Exp Morphol 1972;28(1):163-176
20. Papaioannou VE, McBurney MW, Gardner RL, Evans MJ. Fate of teratocarcinoma cells injected into early mouse embryos. Nature 1975;258(5530):70-73
21. Brinster RL. Participation of teratocarcinoma cells in mouse embryo development. Cancer Res 1976;36(9 pt 2):3412-3414
22. Mintz B, Illmensee K. Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proc Natl Acad Sci USA 1975;72(9):3585-3589
23. Amit M, Carpenter MK, Inokuma MS, et al. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev Biol 2000;227(2):271-278
24. Enver T, Soneji S, Joshi C, et al. Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells. Hum Mol Genet 2005;14(21):3129-3140
25. Friend C, Scher W, Holland J, Sato T. Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide. Proc Natl Acad Sci USA 1971;68:378-382
26. Orkin SH, Harosi FI, Leder P. Differentiation in erythroleukemic cells and their somatic hybrids. Proc Natl Acad Sci USA 1975;72(1):98-102
27. Strickland S, Mahdavi V. The induction of differentiation in teratocarcinoma stem cells by retinoic acid. Cell 1978;15(2):393-403
28. Andrews PW. Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro. Dev Biol 1984;103(2):285-293
29. Kondo M, Wagers AJ, Manz MG, et al. Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu Rev Immunol 2003;21:759-806
30. Price J, Thurlow L. Cell lineage in the rat cerebral cortex: a study using retroviral-mediated gene transfer. Development 1988;104(3):473-482
31. Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992;255(5052):1707-1710
32. Friedenstein AJ, Gorskaja JF, Kulagina NN. Fibroblast precursors in normal and irradiated mouse hematopoietic organs. Exp Hematol 1976;4(5):267-274
33. Conget PA, Minguell JJ. Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. J Cell Physiol 1999;181(1):67-73
34. Devine SM, Cobbs C, Jennings M, Bartholomew A, Hoffman R. Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates. Blood 2003;101(8):2999-3001
35. Mezey E, Chandross KJ, Harta G, Maki RA, McKercher SR. Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow. Science 2000;290(5497):1779-1782
36. Brazelton TR, Rossi FM, Keshet GI, Blau HM. From marrow to brain: expression of neuronal phenotypes in adult mice. Science 2000;290(5497):1775- 1779
37. Lagasse E, Connors H, Al-Dhalimy M, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000;6(11):1229-1234
38. Bjornson CR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL. Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. Science 1999;283(5401):534-537
39. Reyes M, Lund T, Lenvik T, Aguiar D, Koodie L, Verfaillie CM. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 2001;98(9):2615-2625
40. Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002;418(6893):41-49
41. Muguruma Y, Reyes M, Nakamura Y, et al. In vivo and in vitro differentiation of myocytes from human bone marrow-derived multipotent progenitor cells. Exp Hematol 2003;31(12):1323-1330
42. Kawada H, Ogawa M. Bone marrow origin of hematopoietic progenitors and stem cells in murine muscle. Blood 2001;98(7):2008-2013
43. McKinney-Freeman SL, Jackson KA, Camargo FD, Ferrari G, Mavilio F, Goodell MA. Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc Natl Acad Sci USA 2002;99(3):1341-1346
44. Harris H, Sidebottom E, Grace DM, Bramwell ME. The expression of genetic information: a study with hybrid animal cells. J Cell Sci 1969;4(2):499-525
45. Darlington GJ, Rankin JK, Schlanger G. Expression of human hepatic genes in somatic cell hybrids. Somatic Cell Genet 1982;8(3):403-412
46. Rankin JK, Darlington GJ. Expression of human hepatic genes in mouse hepatoma-human amniocyte hybrids. Somatic Cell Genet 1979;5(1):1-10
47. Malawista SE, Weiss MC. Expression of differentiated functions in hepatoma cell hybrids: high frequency of induction of mouse albumin production in rat hepatoma-mouse lymphoblast hybrids. Proc Natl Acad Sci USA 1974;71(3):927-931
48. Ying QL, Nichols J, Evans EP, Smith AG. Changing potency by spontaneous fusion. Nature 2002;416(6880):545-548
49. Terada N, Hamazaki T, Oka M, et al. Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature 2002;416(6880):542-545
50. Boyse EA, Old LJ. Some aspects of normal and abnormal cell surface genetics. Annu Rev Genet 1969;3(1):269-290
51. Morrison SJ, Weissman IL. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1994;1(8):661-673
52. Andrews PW, Casper J, Damjanov I, et al. Comparative analysis of cell surface antigens expressed by cell lines derived from human germ cell tumours. Int J Cancer 1996;66(6):806-816
53. Kannagi R, Nudelman E, Levery SB, Hakomori S. A series of human erythrocyte glycosphingolipids reacting to the monoclonal antibody directed to a developmentally regulated antigen SSEA-1. J Biol Chem 1982;257(24):14865-14874
54. Shevinsky LH, Knowles BB, Damjanov I, Solter D. Monoclonal antibody to murine embryos defines a stage-specific embryonic antigen expressed on mouse embryos and human teratocarcinoma cells. Cell 1982;30(3):697-705
55. Kannagi R, Levery SB, Ishigami F, et al. New globoseries glycosphingolipids in human teratocarcinoma reactive with the monoclonal antibody directed to a developmentally regulated antigen, stage-specific embryonic antigen 3. J Biol Chem 1983;258(14):8934-8942
56. Andrews PW, Banting G, Damjanov I, Arnaud D, Avner P. Three monoclonal antibodies defining distinct differentiation antigens, associated with different high molecular weight polypeptides on the surface of human embryonal carcinoma cells. Hybridoma 1984;3(4):347-361
57. Badcock G, Pigott C, Goepel J, Andrews PW. The human embryonal carcinoma marker antigen TRA-1-60 is a sialylated keratan sulfate proteoglycan. Cancer Res 1999;59(18):4715-4719
58. Pera MF, Blasco-Lafita MJ, Cooper S, Mason M, Mills J, Monaghan P. Analysis of cell-differentiation lineage in human teratomas using new monoclonal antibodies to cytostructural antigens of embryonal carcinoma cells. Differentiation 1988;39(2):139-149
59. Andrews PW, Goodfellow PN, Bronson DL. Cell-surface characteristics and other markers of differentiation of human teratocarcinoma cells in culture. In: Silver LM, Martin GR, Strickland S eds. Teratocarcinoma Stem Cells. Vol. 10. New York: Cold Spring Harbor Laboratory; 1983:579-591
60. Stein H, Gerdes J, Schwab U, et al. Identification of Hodgkin and Sternberg-reed cells as a unique cell type derived from a newly-detected small-cell population. Int J Cancer 1982;30(4):445-459
61. Tippett P, Andrews PW, Knowles BB, Solter D, Goodfellow PN. Red cell antigens P (globoside) and Luke: identification by monoclonal antibodies defining the murine stage-specific embryonic antigens-3 and -4 (SSEA-3 and SSEA-4). Vox Sang 1986;51(1):53-56
62. Draper JS, Pigott C, Thomson JA, Andrews PW. Surface antigens of human embryonic stem cells: changes upon differentiation in culture. J Anat 2002;200(pt 3):249-258
63. Fenderson BA, Andrews PW. Carbohydrate antigens of embryonal carcinoma cells: changes upon differentiation. APMIS 1992;27(suppl):109-118
64. Fenderson BA, Andrews PW, Nudelman E, Clausen H, Hakomori S. Glycolipid core structure switching from globo- to lacto- and ganglio-series during retinoic acid-induced differentiation of TERA-2-derived human embryonal carcinoma cells. Dev Biol 1987;122(1):21-34
65. Brandenberger R, Khrebtukova I, Thies RS, et al. MPSS profiling of human embryonic stem cells. BMC Dev Biol 2004;4:10
66. Brandenberger R, Wei H, Zhang S, et al. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. Nat Biotechnol 2004;22(6):707-716
67. Bhattacharya B, Miura T, Brandenberger R, et al. Gene expression in human embryonic stem cell lines: unique molecular signature. Blood 2004;103(8):2956-2964
68. Richards M, Tan SP, Tan JH, Chan WK, Bongso A. The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells 2004;22(1):51-64
69. Abeyta MJ, Clark AT, Rodriguez RT, Bodnar MS, Pera RA, Firpo MT. Unique gene expression signatures of independently-derived human embryonic stem cell lines. Hum Mol Genet 2004;13(6):601-608
70. Sato N, Sanjuan IM, Heke M, Uchida M, Naef F, Brivanlou AH. Molecular signature of human embryonic stem cells and its comparison with the mouse. Dev Biol 2003;260(2):404-413
71. Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 2003;17(1):126-140
72. Chambers I, Colby D, Robertson M, et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003;113(5):643-655
73. Mitsui K, Tokuzawa Y, Itoh H, et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003;113(5):631-642
74. Nichols J, Zevnik B, Anastassiadis K, et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998;95(3):379-391
75. Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000;24(4):372-376
76. Matin MM, Walsh JR, Gokhale PJ, et al. Specific knockdown of Oct4 and beta2-microglobulin expression by RNA interference in human embryonic stem cells and embryonic carcinoma cells. Stem Cells 2004;22(5):659-668
77. Zaehres H, Lensch MW, Daheron L, Stewart SA, Itskovitz-Eldor J, Daley GQ. High-efficiency RNA interference in human embryonic stem cells. Stem Cells 2005;23(3):299-305
78. Hyslop L, Stojkovic M, Armstrong L, et al. Down-regulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages. Stem Cells 2005;23(8):1035-1043
79. Boyer LA, Lee TI, Cole MF, et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005;122(6):947-956
80. Henderson JK, Draper JS, Baillie HS, et al. Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens. Stem Cells 2002;20(4):329-337
81. Chew JL, Loh YH, Zhang W, et al. Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol 2005;25(14):6031-6046
82. Daheron L, Opitz SL, Zaehres H, et al. LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells. Stem Cells 2004;22(5):770-778
83. Xu RH, Chen X, Li DS, et al. BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol 2002;20(12):1261-1264
84. Vallier L, Alexander M, Pedersen RA. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. J Cell Sci 2005;118(Pt 19):4495-4509
85. James D, Levine AJ, Besser D, Hemmati-Brivanlou A. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 2005;132(6):1273-1282
86. Ying QL, Nichols J, Chambers I, Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003;115(3):281-292
87. Kleinsmith LJ, Pierce GB Jr. Multipotentiality of single embryonal carcinoma cells. Cancer Res 1964;24:1544-1551
88. Markert CL. Neoplasia: a disease of cell differentiation. Cancer Res 1968;28(9):1908-1914
89. Pierce GB. Neoplasms, differentiations and mutations. Am J Pathol 1974;77(1):103-118
90. Cairns J. Mutation selection and the natural history of cancer. Nature 1975;255:197-200
91. Bruce WR, Van Der Gaag H. A quantitative assay for the number of murine lymphoma cells capable of proliferation in vivo. Nature 1963;199:79-80
92. Hamburger AW, Salmon SE. Primary bioassay of human tumor stem cells. Science 1977;197(4302):461-463
93. Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3(7):730-737
94. Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003;63(18):5821-5828
95. Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature 2004;432(7015):396-401
96. Kondo T, Setoguchi T, Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci USA 2004;101(3):781-786
97. Galli R, Binda E, Orfanelli U, et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 2004;64(19):7011-7021
98. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003;100(7):3983-3988
99. Fang D, Nguyen TK, Leishear K, et al. A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 2005;65(20):9328-9337
100. Harris H. Tumour suppression: putting on the brakes. Nature 2004;427(6971):201
101. Liu X, Wu H, Loring J, et al. Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission. Dev Dyn 1997;209(1):85-91
102. Maitra A, Arking DE, Shivapurkar N, et al. Genomic alterations in cultured human embryonic stem cells. Nat Genet 2005;37(10):1099-1103
103. Atkin NB, Baker MC. Specific chromosome change, i(12p), in testicular tumours? Lancet 1982;2(8311):1349
104. Skotheim RI, Lind GE, Monni O, et al. Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development. Cancer Res 2005;65(13):5588-5598
105. Andrews PW, Matin MM, Bahrami AR, Damjanov I, Gokhale P, Draper JS. Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin. Biochem Soc Trans 2005;33(pt 6):1526-1530