Identification of 2,3-epoxymethacrylic acid as an intermediate in the metabolism of dental materials in human liver microsomes

Dental Materials

Volumn 23, Issue 1, 2007, Pages 9-16

  Seiss, Mario ^a   Nitz, Siegfried ^b   Kleinsasser, Norbert ^c   Buters, Jeroen T M ^b   Behrendt, Heidrun ^b   Hickel, Reinhard ^a   Reichl, Franz X ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

2,3 Epoxymethacrylic acid; Human liver microsomes; Metabolism; Methacrylic acid

Indexed keywords

ENZYME INHIBITION; GAS CHROMATOGRAPHY; HYDROLYSIS; MASS SPECTROMETRY; METABOLISM; ORGANIC ACIDS; PH EFFECTS; RATE CONSTANTS; TOXIC MATERIALS;

CYCLOHEXENE OXIDE; DENTAL COMONOMERS; LIVER; METHACRYLIC ACID (MA); MICROSOMES;

DENTAL MATERIALS;

2,3 EPOXYMETHACRYLIC ACID; 2,3-EPOXYMETHACRYLIC ACID; BIOMEDICAL AND DENTAL MATERIALS; CYCLOHEXANE OXIDE; CYCLOHEXENE DERIVATIVE; ENZYME INHIBITOR; EPOXIDE; EPOXIDE HYDROLASE; METHACRYLIC ACID; METHACRYLIC ACID DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; CULTURE TECHNIQUE; DRUG ANTAGONISM; HUMAN; HYDROLYSIS; ISOLATION AND PURIFICATION; LIVER MICROSOME; MASS FRAGMENTOGRAPHY; METABOLISM; PH; TEMPERATURE; TIME;

CULTURE TECHNIQUES; CYCLOHEXENES; DENTAL MATERIALS; ENZYME INHIBITORS; EPOXIDE HYDROLASES; EPOXY COMPOUNDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; METHACRYLATES; MICROSOMES, LIVER; NADP; TEMPERATURE; TIME FACTORS;

EID: 33845312700     PISSN: 01095641     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dental.2005.11.038     Document Type: Article

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