Detoxication Pathways Involving Glutathione and Epoxide Hydrolase in the in Vitro Metabolism of Chloroprene

Chemical Research in Toxicology

Volumn 16, Issue 10, 2003, Pages 1287-1297

  Munter, Tony ^a   Cottrell, Lisa ^a   Golding, Bernard T ^b   Watson, William P ^a  

^a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

(1 CHLOROETHENYL)OXIRANE; 1 CHLORO 4 (GLUTATHIONYL)BUTAN 2 ONE; 1 HYDROXY 4 (GLUTATHIONYL)BUTAN 2 ONE; 1,4 BIS(GLUTATHIONYL)BUTAN 2 ONE; 2 (GLUTATHIONYL)BUTAN 2 ONE; 2 CHLORO 2 ETHENYLOXIRANE; 2 CHLORO 3 HYDROXY 4 (GLUTATHIONYL)BUTENE; ALDEHYDE DERIVATIVE; CLOROFENE; EPOXIDE; EPOXIDE HYDROLASE; ETHYLENE OXIDE; GLUTATHIONE; GLUTATHIONE DERIVATIVE; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHEMICAL STRUCTURE; CHLORINATION; CONTROLLED STUDY; DETOXIFICATION; ENANTIOMER; HUMAN; HUMAN TISSUE; HYDROLYSIS; IN VITRO STUDY; INDUSTRIAL WASTE; LIQUID CHROMATOGRAPHY; LIVER MICROSOME METABOLISM; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; RAT; SPECIES DIFFERENCE; STRUCTURE ANALYSIS; TOXICOKINETICS;

ANIMALS; CHLOROPRENE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EPOXIDE HYDROLASES; EPOXY COMPOUNDS; GLUTATHIONE; HUMANS; HYDROLYSIS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; METABOLIC DETOXICATION, DRUG; MICE; MICROSOMES, LIVER; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; RATS; STEREOISOMERISM;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0142232002     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx034107m     Document Type: Article

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