메뉴 건너뛰기




Volumn 61, Issue 1, 2007, Pages 44-51

Biological characteristics of cancers in the gallbladder and biliary tract and targeted therapy

Author keywords

Biliary tract cancer; Chemotherapy; Gallbladder; Molecular carcinogenesis; Transgenic models

Indexed keywords

2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; ANTINEOPLASTIC AGENT; BEVACIZUMAB; BORTEZOMIB; CAPECITABINE; CARBOPLATIN; CELECOXIB; CETUXIMAB; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; ETOPOSIDE; EVEROLIMUS; FLUOROURACIL; FOLINIC ACID; GEFITINIB; GEMCITABINE; GROWTH FACTOR RECEPTOR; GW 2974; GW 527016; IMATINIB; LAPATINIB; MITOMYCIN C; PERTUZUMAB; PROSTAGLANDIN SYNTHASE; RAPAMYCIN; SORAFENIB; TRASTUZUMAB;

EID: 33845296152     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2006.07.006     Document Type: Review
Times cited : (39)

References (109)
  • 2
    • 1242314802 scopus 로고    scopus 로고
    • Rising incidence of intrahepatic cholangiocarcinoma in the United States: a true increase?
    • Shaib Y.H., Davila J.A., McGlynn K., and El-Serag H.B. Rising incidence of intrahepatic cholangiocarcinoma in the United States: a true increase?. J Hepatol 40 3 (2004) 472-477
    • (2004) J Hepatol , vol.40 , Issue.3 , pp. 472-477
    • Shaib, Y.H.1    Davila, J.A.2    McGlynn, K.3    El-Serag, H.B.4
  • 3
    • 2942615272 scopus 로고    scopus 로고
    • The epidemiology of cholangiocarcinoma
    • Shaib Y., and El-Serag H.B. The epidemiology of cholangiocarcinoma. Semin Liver Dis 24 2 (2004) 115-125
    • (2004) Semin Liver Dis , vol.24 , Issue.2 , pp. 115-125
    • Shaib, Y.1    El-Serag, H.B.2
  • 4
    • 0034790895 scopus 로고    scopus 로고
    • Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma
    • [discussion 517-9]
    • Jarnagin W.R., Fong Y., DeMatteo R.P., Gonen M., Burke E.C., Bodniewicz B.S.J., et al. Staging, resectability, and outcome in 225 patients with hilar cholangiocarcinoma. Ann Surg 234 4 (2001) 507-517 [discussion 517-9]
    • (2001) Ann Surg , vol.234 , Issue.4 , pp. 507-517
    • Jarnagin, W.R.1    Fong, Y.2    DeMatteo, R.P.3    Gonen, M.4    Burke, E.C.5    Bodniewicz, B.S.J.6
  • 5
    • 0033777650 scopus 로고    scopus 로고
    • Cholangiocarcinoma of the extrahepatic bile ducts
    • Jarnagin W.R. Cholangiocarcinoma of the extrahepatic bile ducts. Semin Surg Oncol 19 2 (2000) 156-176
    • (2000) Semin Surg Oncol , vol.19 , Issue.2 , pp. 156-176
    • Jarnagin, W.R.1
  • 6
    • 0025816899 scopus 로고
    • Primary "brown pigment" bile duct stones
    • [discussion 221-2]
    • Vitetta L., Sali A., Little P., Nayman J., and Elzarka A. Primary "brown pigment" bile duct stones. HPB Surg 4 3 (1991) 209-220 [discussion 221-2]
    • (1991) HPB Surg , vol.4 , Issue.3 , pp. 209-220
    • Vitetta, L.1    Sali, A.2    Little, P.3    Nayman, J.4    Elzarka, A.5
  • 7
  • 8
    • 0031966040 scopus 로고    scopus 로고
    • Gallbladder carcinoma-an unexpected finding after laparoscopic cholecystectomy
    • Hohaus T., Hellmich G., Freitag M., and Ludwig K. Gallbladder carcinoma-an unexpected finding after laparoscopic cholecystectomy. Zentralbl Chir 123 Suppl 2 (1998) 80-83
    • (1998) Zentralbl Chir , vol.123 , Issue.SUPPL. 2 , pp. 80-83
    • Hohaus, T.1    Hellmich, G.2    Freitag, M.3    Ludwig, K.4
  • 9
    • 0030936341 scopus 로고    scopus 로고
    • [Incidental gallbladder carcinoma-a report of experiences after 1,200 laparoscopic cholecystectomies]
    • Hohaus T., Hellmich G., and Ludwig K. [Incidental gallbladder carcinoma-a report of experiences after 1,200 laparoscopic cholecystectomies]. Zentralbl Chir 122 2 (1997) 103-107
    • (1997) Zentralbl Chir , vol.122 , Issue.2 , pp. 103-107
    • Hohaus, T.1    Hellmich, G.2    Ludwig, K.3
  • 10
    • 12144255926 scopus 로고    scopus 로고
    • The surgical management of incidental gallbladder carcinoma
    • Yildirim E., Celen O., Gulben K., and Berberoglu U. The surgical management of incidental gallbladder carcinoma. Eur J Surg Oncol 31 1 (2005) 45-52
    • (2005) Eur J Surg Oncol , vol.31 , Issue.1 , pp. 45-52
    • Yildirim, E.1    Celen, O.2    Gulben, K.3    Berberoglu, U.4
  • 11
    • 0034569572 scopus 로고    scopus 로고
    • Precancerous conditions of gallbladder carcinoma: overview of histopathologic characteristics and molecular genetic findings
    • Sasatomi E., Tokunaga O., and Miyazaki K. Precancerous conditions of gallbladder carcinoma: overview of histopathologic characteristics and molecular genetic findings. J Hepatobiliary Pancreat Surg 7 6 (2000) 556-567
    • (2000) J Hepatobiliary Pancreat Surg , vol.7 , Issue.6 , pp. 556-567
    • Sasatomi, E.1    Tokunaga, O.2    Miyazaki, K.3
  • 12
    • 0034575953 scopus 로고    scopus 로고
    • Precancerous conditions of biliary tract cancer in patients with pancreaticobiliary maljunction: reappraisal of nationwide survey in Japan
    • Hasumi A., Matsui H., Sugioka A., Uyama I., Komori Y., Fujita J., et al. Precancerous conditions of biliary tract cancer in patients with pancreaticobiliary maljunction: reappraisal of nationwide survey in Japan. J Hepatobiliary Pancreat Surg 7 6 (2000) 551-555
    • (2000) J Hepatobiliary Pancreat Surg , vol.7 , Issue.6 , pp. 551-555
    • Hasumi, A.1    Matsui, H.2    Sugioka, A.3    Uyama, I.4    Komori, Y.5    Fujita, J.6
  • 13
    • 14844315003 scopus 로고    scopus 로고
    • Effect of hepatitis C virus core protein on modulation of cellular proliferation and apoptosis in hilar cholangiocarcinoma
    • Chen R.F., Li Z.H., Zou S.Q., and Chen J.S. Effect of hepatitis C virus core protein on modulation of cellular proliferation and apoptosis in hilar cholangiocarcinoma. Hepatobiliary Pancreat Dis Int 4 1 (2005) 71-74
    • (2005) Hepatobiliary Pancreat Dis Int , vol.4 , Issue.1 , pp. 71-74
    • Chen, R.F.1    Li, Z.H.2    Zou, S.Q.3    Chen, J.S.4
  • 14
    • 0032807706 scopus 로고    scopus 로고
    • Risk factors for biliary tract carcinogenesis
    • Chapman R.W. Risk factors for biliary tract carcinogenesis. Ann Oncol 10 Suppl 4 (1999) 308-311
    • (1999) Ann Oncol , vol.10 , Issue.SUPPL. 4 , pp. 308-311
    • Chapman, R.W.1
  • 16
    • 0036208350 scopus 로고    scopus 로고
    • Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line
    • Yoon J.H., Higuchi H., Werneburg N.W., Kaufmann S.H., and Gores G.J. Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line. Gastroenterology 122 4 (2002) 985-993
    • (2002) Gastroenterology , vol.122 , Issue.4 , pp. 985-993
    • Yoon, J.H.1    Higuchi, H.2    Werneburg, N.W.3    Kaufmann, S.H.4    Gores, G.J.5
  • 17
    • 0037112523 scopus 로고    scopus 로고
    • Bile acids inhibit Mcl-1 protein turnover via an epidermal growth factor receptor/Raf-1-dependent mechanism
    • Yoon J.H., Werneburg N.W., Higuchi H., Canbay A.E., Kaufmann S.H., Akgul C., et al. Bile acids inhibit Mcl-1 protein turnover via an epidermal growth factor receptor/Raf-1-dependent mechanism. Cancer Res 62 22 (2002) 6500-6505
    • (2002) Cancer Res , vol.62 , Issue.22 , pp. 6500-6505
    • Yoon, J.H.1    Werneburg, N.W.2    Higuchi, H.3    Canbay, A.E.4    Kaufmann, S.H.5    Akgul, C.6
  • 18
    • 0037966128 scopus 로고    scopus 로고
    • Squamous-cell and non-squamous-cell carcinomas of the gallbladder have different risk factors
    • Andrea C., and Francesco C. Squamous-cell and non-squamous-cell carcinomas of the gallbladder have different risk factors. Lancet Oncol 4 7 (2003) 393-394
    • (2003) Lancet Oncol , vol.4 , Issue.7 , pp. 393-394
    • Andrea, C.1    Francesco, C.2
  • 21
    • 0030020044 scopus 로고    scopus 로고
    • Malignant hepatic hilar tumors: can ultrasonography be used as an alternative to angiography with CT arterial portography for determination of resectability?
    • Hann L.E., Fong Y., Shriver C.D., Botet J.F., Brown K.T., Klimstra D.S., et al. Malignant hepatic hilar tumors: can ultrasonography be used as an alternative to angiography with CT arterial portography for determination of resectability?. J Ultrasound Med 15 1 (1996) 37-45
    • (1996) J Ultrasound Med , vol.15 , Issue.1 , pp. 37-45
    • Hann, L.E.1    Fong, Y.2    Shriver, C.D.3    Botet, J.F.4    Brown, K.T.5    Klimstra, D.S.6
  • 22
    • 0029785467 scopus 로고    scopus 로고
    • Hepatic lobar atrophy: association with ipsilateral portal vein obstruction
    • Hann L.E., Fong Y., Shriver C.D., Botet J.F., Brown K.T., Klimstra D.S., et al. Hepatic lobar atrophy: association with ipsilateral portal vein obstruction. Am J Roentgenol 167 4 (1996) 1017-1021
    • (1996) Am J Roentgenol , vol.167 , Issue.4 , pp. 1017-1021
    • Hann, L.E.1    Fong, Y.2    Shriver, C.D.3    Botet, J.F.4    Brown, K.T.5    Klimstra, D.S.6
  • 25
    • 3042606326 scopus 로고    scopus 로고
    • Laparoscopic cholecystectomy: its effect on the prognosis of patients with gallbladder cancer
    • de Aretxabala X.A., Roa I.S., Mora J.P., Orellana J.J., Riedeman J.P., Burgos L.A., et al. Laparoscopic cholecystectomy: its effect on the prognosis of patients with gallbladder cancer. World J Surg 28 6 (2004) 544-547
    • (2004) World J Surg , vol.28 , Issue.6 , pp. 544-547
    • de Aretxabala, X.A.1    Roa, I.S.2    Mora, J.P.3    Orellana, J.J.4    Riedeman, J.P.5    Burgos, L.A.6
  • 26
  • 27
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: back to Virchow?
    • Balkwill F., and Mantovani A. Inflammation and cancer: back to Virchow?. Lancet 357 9255 (2001) 539-545
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 28
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens L.M., and Werb Z. Inflammation and cancer. Nature 420 6917 (2002) 860-867
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 30
    • 0036177671 scopus 로고    scopus 로고
    • Cyclooxygenase-2: a therapeutic target
    • Turini M.E., and DuBois R.N. Cyclooxygenase-2: a therapeutic target. Annu Rev Med 53 (2002) 35-57
    • (2002) Annu Rev Med , vol.53 , pp. 35-57
    • Turini, M.E.1    DuBois, R.N.2
  • 31
    • 0033590207 scopus 로고    scopus 로고
    • The role of cyclooxygenases in inflammation, cancer, and development
    • Williams C.S., Mann M., and DuBois R.N. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 18 55 (1999) 7908-7916
    • (1999) Oncogene , vol.18 , Issue.55 , pp. 7908-7916
    • Williams, C.S.1    Mann, M.2    DuBois, R.N.3
  • 32
    • 0032483712 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors in tumorigenesis (Part II)
    • Taketo M.M. Cyclooxygenase-2 inhibitors in tumorigenesis (Part II). J Natl Cancer Inst 90 21 (1998) 1609-1620
    • (1998) J Natl Cancer Inst , vol.90 , Issue.21 , pp. 1609-1620
    • Taketo, M.M.1
  • 33
    • 0032556188 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors in tumorigenesis (part I)
    • Taketo M.M. Cyclooxygenase-2 inhibitors in tumorigenesis (part I). J Natl Cancer Inst 90 20 (1998) 1529-1536
    • (1998) J Natl Cancer Inst , vol.90 , Issue.20 , pp. 1529-1536
    • Taketo, M.M.1
  • 34
    • 0027993458 scopus 로고
    • Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas
    • Eberhart C.E., Coffey R.J., Radhika A., Giardiello F.M., Ferrenbach S., and DuBois R.N. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 107 4 (1994) 1183-1188
    • (1994) Gastroenterology , vol.107 , Issue.4 , pp. 1183-1188
    • Eberhart, C.E.1    Coffey, R.J.2    Radhika, A.3    Giardiello, F.M.4    Ferrenbach, S.5    DuBois, R.N.6
  • 35
    • 0034802512 scopus 로고    scopus 로고
    • Differential expression of cyclooxygenase-2 (COX-2) in human bile duct epithelial cells and bile duct neoplasm
    • Hayashi N., Yamamoto H., Hiraoka N., Dono K., Ito Y., Okami J., et al. Differential expression of cyclooxygenase-2 (COX-2) in human bile duct epithelial cells and bile duct neoplasm. Hepatology 34 4 Pt 1 (2001) 638-650
    • (2001) Hepatology , vol.34 , Issue.4 PART 1 , pp. 638-650
    • Hayashi, N.1    Yamamoto, H.2    Hiraoka, N.3    Dono, K.4    Ito, Y.5    Okami, J.6
  • 36
    • 0036322129 scopus 로고    scopus 로고
    • ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions
    • Hayashi N., Yamamoto H., Hiraoka N., Dono K., Ito Y., and Okami J. ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions. Hepatology 36 2 (2002) 439-450
    • (2002) Hepatology , vol.36 , Issue.2 , pp. 439-450
    • Hayashi, N.1    Yamamoto, H.2    Hiraoka, N.3    Dono, K.4    Ito, Y.5    Okami, J.6
  • 38
    • 0035032319 scopus 로고    scopus 로고
    • Biliary cancer growth factor pathways, cyclo-oxygenase-2 and potential therapeutic strategies
    • Sirica A.E., Lai G.H., and Zhang Z. Biliary cancer growth factor pathways, cyclo-oxygenase-2 and potential therapeutic strategies. J Gastroenterol Hepatol 16 4 (2001) 363-372
    • (2001) J Gastroenterol Hepatol , vol.16 , Issue.4 , pp. 363-372
    • Sirica, A.E.1    Lai, G.H.2    Zhang, Z.3
  • 39
    • 0036191920 scopus 로고    scopus 로고
    • COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells
    • Nzeako U.C., Guicciardi M.E., Yoon J.H., Bronk S.F., and Gores G.J. COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells. Hepatology 35 3 (2002) 552-559
    • (2002) Hepatology , vol.35 , Issue.3 , pp. 552-559
    • Nzeako, U.C.1    Guicciardi, M.E.2    Yoon, J.H.3    Bronk, S.F.4    Gores, G.J.5
  • 41
    • 0035118561 scopus 로고    scopus 로고
    • Expression and clinical significance of the erbB family in intrahepatic cholangiocellular carcinoma
    • Ito Y., Takeda T., Sasaki Y., Sakon M., Yamada T., Ishiguro S., et al. Expression and clinical significance of the erbB family in intrahepatic cholangiocellular carcinoma. Pathol Res Pract 197 2 (2001) 95-100
    • (2001) Pathol Res Pract , vol.197 , Issue.2 , pp. 95-100
    • Ito, Y.1    Takeda, T.2    Sasaki, Y.3    Sakon, M.4    Yamada, T.5    Ishiguro, S.6
  • 42
    • 0024843763 scopus 로고
    • Oncogene expression in cholangiocarcinoma and in normal hepatic development
    • Voravud N., Foster C.S., Gilbertson J.A., Sikora K., and Waxman J. Oncogene expression in cholangiocarcinoma and in normal hepatic development. Human Pathol 20 12 (1989) 1163-1168
    • (1989) Human Pathol , vol.20 , Issue.12 , pp. 1163-1168
    • Voravud, N.1    Foster, C.S.2    Gilbertson, J.A.3    Sikora, K.4    Waxman, J.5
  • 43
    • 0030689866 scopus 로고    scopus 로고
    • NEU overexpression in the furan rat model of cholangiocarcinogenesis compared with biliary ductal cell hyperplasia
    • Sirica A.E., Radaeva S., and Caran N. NEU overexpression in the furan rat model of cholangiocarcinogenesis compared with biliary ductal cell hyperplasia. Am J Pathol 151 6 (1997) 1685-1694
    • (1997) Am J Pathol , vol.151 , Issue.6 , pp. 1685-1694
    • Sirica, A.E.1    Radaeva, S.2    Caran, N.3
  • 44
    • 0028869784 scopus 로고
    • Significance of c-erbB-2 expression in normal and neoplastic epithelium of biliary tract
    • Chow N.H., Huang S.M., Chan S.H., Mo L.R., Hwang M.H., and Su W.C. Significance of c-erbB-2 expression in normal and neoplastic epithelium of biliary tract. Anticancer Res 15 3 (1995) 1055-1059
    • (1995) Anticancer Res , vol.15 , Issue.3 , pp. 1055-1059
    • Chow, N.H.1    Huang, S.M.2    Chan, S.H.3    Mo, L.R.4    Hwang, M.H.5    Su, W.C.6
  • 45
    • 0036697788 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and ERBB-2 in cholangiocarcinoma: potential therapeutic targets
    • Sirica A.E., Lai G.H., Endo K., Zhang Z., and Yoon B.I. Cyclooxygenase-2 and ERBB-2 in cholangiocarcinoma: potential therapeutic targets. Semin Liver Dis 22 3 (2002) 303-313
    • (2002) Semin Liver Dis , vol.22 , Issue.3 , pp. 303-313
    • Sirica, A.E.1    Lai, G.H.2    Endo, K.3    Zhang, Z.4    Yoon, B.I.5
  • 46
    • 0035476235 scopus 로고    scopus 로고
    • Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma
    • Kiguchi K., Carbajal S., Chan K., Beltran L., Ruffino L., Shen J., et al. Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma. Cancer Res 61 19 (2001) 6971-6976
    • (2001) Cancer Res , vol.61 , Issue.19 , pp. 6971-6976
    • Kiguchi, K.1    Carbajal, S.2    Chan, K.3    Beltran, L.4    Ruffino, L.5    Shen, J.6
  • 47
    • 0031908120 scopus 로고    scopus 로고
    • Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing the neu oncogene under the control of the bovine keratin 5 promoter
    • Bol D., Kiguchi K., Beltran L., Rupp T., Moats S., Gimenez-Conti I., et al. Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing the neu oncogene under the control of the bovine keratin 5 promoter. Mol Carcinog 21 1 (1998) 2-12
    • (1998) Mol Carcinog , vol.21 , Issue.1 , pp. 2-12
    • Bol, D.1    Kiguchi, K.2    Beltran, L.3    Rupp, T.4    Moats, S.5    Gimenez-Conti, I.6
  • 48
    • 0036006453 scopus 로고    scopus 로고
    • Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
    • Pai R., Soreghan B., Szabo I.L., Pavelka M., Baatar D., and Tarnawski A.S. Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat Med 8 3 (2002) 289-293
    • (2002) Nat Med , vol.8 , Issue.3 , pp. 289-293
    • Pai, R.1    Soreghan, B.2    Szabo, I.L.3    Pavelka, M.4    Baatar, D.5    Tarnawski, A.S.6
  • 49
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: structures, properties, and functions
    • Narumiya S., Sugimoto Y., and Ushikubi F. Prostanoid receptors: structures, properties, and functions. Physiol Rev 79 4 (1999) 1193-1226
    • (1999) Physiol Rev , vol.79 , Issue.4 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 50
    • 23044494419 scopus 로고    scopus 로고
    • Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinoma
    • Kiguchi K., Ruffino L., Kawamoto T., Ajiki T., and Digiovanni J. Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinoma. Clin Cancer Res 11 15 (2005) 5572-5580
    • (2005) Clin Cancer Res , vol.11 , Issue.15 , pp. 5572-5580
    • Kiguchi, K.1    Ruffino, L.2    Kawamoto, T.3    Ajiki, T.4    Digiovanni, J.5
  • 51
    • 20144377465 scopus 로고    scopus 로고
    • HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells
    • Hirata A., Hosoi F., Miyagawa M., Ueda S., Naito S., Fujii T., et al. HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells. Cancer Res 65 10 (2005) 4253-4260
    • (2005) Cancer Res , vol.65 , Issue.10 , pp. 4253-4260
    • Hirata, A.1    Hosoi, F.2    Miyagawa, M.3    Ueda, S.4    Naito, S.5    Fujii, T.6
  • 52
    • 14644392200 scopus 로고    scopus 로고
    • Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation
    • Diermeier S., Horvath G., Knuechel-Clarke R., Hofstaedter F., Szollosi J., and Brockhoff G. Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation. Exp Cell Res 304 2 (2005) 604-619
    • (2005) Exp Cell Res , vol.304 , Issue.2 , pp. 604-619
    • Diermeier, S.1    Horvath, G.2    Knuechel-Clarke, R.3    Hofstaedter, F.4    Szollosi, J.5    Brockhoff, G.6
  • 53
    • 18844365440 scopus 로고    scopus 로고
    • Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors
    • Chan C.T., Metz M.Z., and Kane S.E. Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors. Breast Cancer Res Treat 91 2 (2005) 187-201
    • (2005) Breast Cancer Res Treat , vol.91 , Issue.2 , pp. 187-201
    • Chan, C.T.1    Metz, M.Z.2    Kane, S.E.3
  • 54
    • 20144376651 scopus 로고    scopus 로고
    • Initial experience from a combination of systemic and regional chemotherapy in the treatment of patients with nonresectable cholangiocellular carcinoma in the liver
    • Kirchhoff T., Zender L., Merkesdal S., Frericks B., Malek N., Bleck J., et al. Initial experience from a combination of systemic and regional chemotherapy in the treatment of patients with nonresectable cholangiocellular carcinoma in the liver. World J Gastroenterol 11 8 (2005) 1091-1095
    • (2005) World J Gastroenterol , vol.11 , Issue.8 , pp. 1091-1095
    • Kirchhoff, T.1    Zender, L.2    Merkesdal, S.3    Frericks, B.4    Malek, N.5    Bleck, J.6
  • 55
    • 2642532029 scopus 로고    scopus 로고
    • Cholangiocellular and gallbladder carcinoma
    • Kubicka S. Cholangiocellular and gallbladder carcinoma. Z Gastroenterol 42 5 (2004) 397-402
    • (2004) Z Gastroenterol , vol.42 , Issue.5 , pp. 397-402
    • Kubicka, S.1
  • 56
    • 0034943861 scopus 로고    scopus 로고
    • Phase II study of systemic gemcitabine chemotherapy for advanced unresectable hepatobiliary carcinomas
    • Kubicka S., Rudolph K.L., Tietze M.K., Lorenz M., and Manns M. Phase II study of systemic gemcitabine chemotherapy for advanced unresectable hepatobiliary carcinomas. Hepatogastroenterology 48 39 (2001) 783-789
    • (2001) Hepatogastroenterology , vol.48 , Issue.39 , pp. 783-789
    • Kubicka, S.1    Rudolph, K.L.2    Tietze, M.K.3    Lorenz, M.4    Manns, M.5
  • 57
    • 0032526183 scopus 로고    scopus 로고
    • A phase II trial of 5-fluorouracil, leucovorin, and carboplatin in patients with unresectable biliary tree carcinoma
    • Sanz-Altamira P.M., Ferrante K., Jenkins R.L., Lewis W.D., Huberman M.S., and Stuart K.E. A phase II trial of 5-fluorouracil, leucovorin, and carboplatin in patients with unresectable biliary tree carcinoma. Cancer 82 12 (1998) 2321-2325
    • (1998) Cancer , vol.82 , Issue.12 , pp. 2321-2325
    • Sanz-Altamira, P.M.1    Ferrante, K.2    Jenkins, R.L.3    Lewis, W.D.4    Huberman, M.S.5    Stuart, K.E.6
  • 58
    • 17544403541 scopus 로고    scopus 로고
    • 5-FU, folinic acid and cisplatin (LV5FU2-P) for unresectable pancreatic cancer
    • Taieb J., Lecomte T., Ezenfis J., Artru P., Mitry E., Boige V., et al. 5-FU, folinic acid and cisplatin (LV5FU2-P) for unresectable pancreatic cancer. Gastroenterol Clin Biol 26 6-7 (2002) 605-609
    • (2002) Gastroenterol Clin Biol , vol.26 , Issue.6-7 , pp. 605-609
    • Taieb, J.1    Lecomte, T.2    Ezenfis, J.3    Artru, P.4    Mitry, E.5    Boige, V.6
  • 59
    • 20244371852 scopus 로고    scopus 로고
    • Combining gemcitabine and capecitabine in patients with advanced biliary cancer: a phase II trial
    • Knox J.J., Hedley D., Oza A., Feld R., Siu L.L., Chen E., et al. Combining gemcitabine and capecitabine in patients with advanced biliary cancer: a phase II trial. J Clin Oncol 23 10 (2005) 2332-2338
    • (2005) J Clin Oncol , vol.23 , Issue.10 , pp. 2332-2338
    • Knox, J.J.1    Hedley, D.2    Oza, A.3    Feld, R.4    Siu, L.L.5    Chen, E.6
  • 60
    • 0032907615 scopus 로고    scopus 로고
    • Two consecutive phase II studies of 5-fluorouracil/leucovorin/mitomycin C and of gemcitabine in patients with advanced biliary cancer
    • Raderer M., Hejna M.H., Valencak J.B., Kornek G.V., Weinlander G.S., Bareck E., et al. Two consecutive phase II studies of 5-fluorouracil/leucovorin/mitomycin C and of gemcitabine in patients with advanced biliary cancer. Oncology 56 3 (1999) 177-180
    • (1999) Oncology , vol.56 , Issue.3 , pp. 177-180
    • Raderer, M.1    Hejna, M.H.2    Valencak, J.B.3    Kornek, G.V.4    Weinlander, G.S.5    Bareck, E.6
  • 61
    • 8044236424 scopus 로고    scopus 로고
    • Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer
    • Glimelius B., Ekstrom K., Hoffman K., Graf W., Sjoden P.O., Haglund U., et al. Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer. Ann Oncol 8 2 (1997) 163-168
    • (1997) Ann Oncol , vol.8 , Issue.2 , pp. 163-168
    • Glimelius, B.1    Ekstrom, K.2    Hoffman, K.3    Graf, W.4    Sjoden, P.O.5    Haglund, U.6
  • 62
    • 14644410398 scopus 로고    scopus 로고
    • Phase II study of gemcitabine and cisplatin as first-line chemotherapy in inoperable biliary tract carcinoma
    • Thongprasert S., Napapan S., Charoentum C., and Moonprakan S. Phase II study of gemcitabine and cisplatin as first-line chemotherapy in inoperable biliary tract carcinoma. Ann Oncol 16 2 (2005) 279-281
    • (2005) Ann Oncol , vol.16 , Issue.2 , pp. 279-281
    • Thongprasert, S.1    Napapan, S.2    Charoentum, C.3    Moonprakan, S.4
  • 63
    • 0028053595 scopus 로고
    • A phase II study of cisplatin in patients with biliary tract carcinoma
    • Okada S., Ishii H., Nose H., Yoshimori M., Okusaka T., Aoki K., et al. A phase II study of cisplatin in patients with biliary tract carcinoma. Oncology 51 6 (1994) 515-517
    • (1994) Oncology , vol.51 , Issue.6 , pp. 515-517
    • Okada, S.1    Ishii, H.2    Nose, H.3    Yoshimori, M.4    Okusaka, T.5    Aoki, K.6
  • 64
    • 21344438897 scopus 로고    scopus 로고
    • Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers
    • Nakazawa K., Dobashi Y., Suzuki S., Fujii H., Takeda Y., and Ooi A. Amplification and overexpression of c-erbB-2, epidermal growth factor receptor, and c-met in biliary tract cancers. J Pathol 206 3 (2005) 356-365
    • (2005) J Pathol , vol.206 , Issue.3 , pp. 356-365
    • Nakazawa, K.1    Dobashi, Y.2    Suzuki, S.3    Fujii, H.4    Takeda, Y.5    Ooi, A.6
  • 65
    • 33644998898 scopus 로고    scopus 로고
    • Gefitinib, a selective EGFR tyrosine kinase inhibitor, induces apoptosis through activation of Bax in human gallbladder adenocarcinoma cells
    • Ariyama H., Qin B., Baba E., Tanaka R., Mitsugi K., Harada M., et al. Gefitinib, a selective EGFR tyrosine kinase inhibitor, induces apoptosis through activation of Bax in human gallbladder adenocarcinoma cells. J Cell Biochem 97 4 (2006) 724-734
    • (2006) J Cell Biochem , vol.97 , Issue.4 , pp. 724-734
    • Ariyama, H.1    Qin, B.2    Baba, E.3    Tanaka, R.4    Mitsugi, K.5    Harada, M.6
  • 66
    • 0031881619 scopus 로고    scopus 로고
    • Technetium-99m-labeled anti-EGF-receptor antibody in patients with tumor of epithelial origin. I. Biodistribution and dosimetry for radioimmunotherapy
    • Iznaga-Escobar N., Torres L.A., Morales A., Ramos M., Alvarez I., Perez N., et al. Technetium-99m-labeled anti-EGF-receptor antibody in patients with tumor of epithelial origin. I. Biodistribution and dosimetry for radioimmunotherapy. J Nucl Med 39 1 (1998) 15-23
    • (1998) J Nucl Med , vol.39 , Issue.1 , pp. 15-23
    • Iznaga-Escobar, N.1    Torres, L.A.2    Morales, A.3    Ramos, M.4    Alvarez, I.5    Perez, N.6
  • 67
    • 0031939008 scopus 로고    scopus 로고
    • Transforming growth factor alpha immunoreactivity in human gallbladder and extrahepatic biliary tract tumours
    • Lee C.S. Transforming growth factor alpha immunoreactivity in human gallbladder and extrahepatic biliary tract tumours. Eur J Surg Oncol 24 1 (1998) 38-42
    • (1998) Eur J Surg Oncol , vol.24 , Issue.1 , pp. 38-42
    • Lee, C.S.1
  • 68
    • 0029594122 scopus 로고
    • Epidermal growth factor receptor immunoreactivity in gallbladder and extrahepatic biliary tract tumours
    • Lee C.S., and Pirdas A. Epidermal growth factor receptor immunoreactivity in gallbladder and extrahepatic biliary tract tumours. Pathol Res Pract 191 11 (1995) 1087-1091
    • (1995) Pathol Res Pract , vol.191 , Issue.11 , pp. 1087-1091
    • Lee, C.S.1    Pirdas, A.2
  • 69
    • 3042853065 scopus 로고    scopus 로고
    • Gallbladder cancer: current status
    • Malik I.A. Gallbladder cancer: current status. Exp Opin Pharmacother 5 6 (2004) 1271-1277
    • (2004) Exp Opin Pharmacother , vol.5 , Issue.6 , pp. 1271-1277
    • Malik, I.A.1
  • 70
    • 32144454743 scopus 로고    scopus 로고
    • Immunohistochemical expression of HER-1 and HER-2 in extrahepatic biliary carcinoma
    • Ogo Y., Nio Y., Yano S., Toga T., Koike M., Hashimoto K., et al. Immunohistochemical expression of HER-1 and HER-2 in extrahepatic biliary carcinoma. Anticancer Res 26 1B (2006) 763-770
    • (2006) Anticancer Res , vol.26 , Issue.1 B , pp. 763-770
    • Ogo, Y.1    Nio, Y.2    Yano, S.3    Toga, T.4    Koike, M.5    Hashimoto, K.6
  • 71
    • 0028502171 scopus 로고
    • Expression of epidermal growth factor receptor in gallbladder cancer
    • Valerdiz-Casasola S. Expression of epidermal growth factor receptor in gallbladder cancer. Human Pathol 25 9 (1994) 964-965
    • (1994) Human Pathol , vol.25 , Issue.9 , pp. 964-965
    • Valerdiz-Casasola, S.1
  • 72
    • 0042387812 scopus 로고    scopus 로고
    • Significance of expression of epidermal growth factor (EGF) and its receptor (EGFR) in chronic cholecystitis and gallbladder carcinoma
    • Zhou Y.M., Li Y.M., Cao N., Feng Y., and Zeng F. Significance of expression of epidermal growth factor (EGF) and its receptor (EGFR) in chronic cholecystitis and gallbladder carcinoma. Ai Zheng 22 3 (2003) 262-265
    • (2003) Ai Zheng , vol.22 , Issue.3 , pp. 262-265
    • Zhou, Y.M.1    Li, Y.M.2    Cao, N.3    Feng, Y.4    Zeng, F.5
  • 73
    • 13144277690 scopus 로고    scopus 로고
    • Gallbladder cancers rarely overexpress HER-2/neu, demonstrated by Hercep test
    • Matsuyama S., Kitajima Y., Sumi K., Mori D., Satoh T., and Miyazaki K. Gallbladder cancers rarely overexpress HER-2/neu, demonstrated by Hercep test. Oncol Rep 11 4 (2004) 815-819
    • (2004) Oncol Rep , vol.11 , Issue.4 , pp. 815-819
    • Matsuyama, S.1    Kitajima, Y.2    Sumi, K.3    Mori, D.4    Satoh, T.5    Miyazaki, K.6
  • 74
    • 0036134223 scopus 로고    scopus 로고
    • C-met and hepatocyte growth factor expression in combined hepatocellular and cholangiocarcinoma
    • Varnholt H., Asayama Y., Aishima S., Taguchi K., Sugimachi K., and Tsuneyoshi M. C-met and hepatocyte growth factor expression in combined hepatocellular and cholangiocarcinoma. Oncol Rep 9 1 (2002) 35-41
    • (2002) Oncol Rep , vol.9 , Issue.1 , pp. 35-41
    • Varnholt, H.1    Asayama, Y.2    Aishima, S.3    Taguchi, K.4    Sugimachi, K.5    Tsuneyoshi, M.6
  • 76
    • 0034234736 scopus 로고    scopus 로고
    • Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells
    • Yokomuro S., Tsuji H., Lunz III J.G., Sakamoto T., Ezure T., Murase N., et al. Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells. Hepatology 32 1 (2000) 26-35
    • (2000) Hepatology , vol.32 , Issue.1 , pp. 26-35
    • Yokomuro, S.1    Tsuji, H.2    Lunz III, J.G.3    Sakamoto, T.4    Ezure, T.5    Murase, N.6
  • 77
    • 0031912249 scopus 로고    scopus 로고
    • Immunohistochemical demonstration of MET overexpression in human intrahepatic cholangiocarcinoma and in hepatolithiasis
    • Terada T., Nakanuma Y., and Sirica A.E. Immunohistochemical demonstration of MET overexpression in human intrahepatic cholangiocarcinoma and in hepatolithiasis. Human Pathol 29 2 (1998) 175-180
    • (1998) Human Pathol , vol.29 , Issue.2 , pp. 175-180
    • Terada, T.1    Nakanuma, Y.2    Sirica, A.E.3
  • 78
    • 21244478673 scopus 로고    scopus 로고
    • Reappraisal of percutaneous transhepatic cholangioscopic lithotomy for primary hepatolithiasis
    • Chen C., Huang M., Yang J., Yang C., Yeh Y., and Wu H. Reappraisal of percutaneous transhepatic cholangioscopic lithotomy for primary hepatolithiasis. Surg Endosc 19 4 (2005) 505-509
    • (2005) Surg Endosc , vol.19 , Issue.4 , pp. 505-509
    • Chen, C.1    Huang, M.2    Yang, J.3    Yang, C.4    Yeh, Y.5    Wu, H.6
  • 79
    • 0037133576 scopus 로고    scopus 로고
    • Bombesin antagonists inhibit growth of MDA-MB-435 estrogen-independent breast cancers and decrease the expression of the ErbB-2/HER-2 oncoprotein and c-jun and c-fos oncogenes
    • Bajo A.M., Schally A.V., Krupa M., Hebert F., Groot K., and Szepeshazi K. Bombesin antagonists inhibit growth of MDA-MB-435 estrogen-independent breast cancers and decrease the expression of the ErbB-2/HER-2 oncoprotein and c-jun and c-fos oncogenes. Proc Natl Acad Sci USA 99 6 (2002) 3836-3841
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.6 , pp. 3836-3841
    • Bajo, A.M.1    Schally, A.V.2    Krupa, M.3    Hebert, F.4    Groot, K.5    Szepeshazi, K.6
  • 80
    • 33644696628 scopus 로고    scopus 로고
    • Analysis of p53 and vascular endothelial growth factor expression in human gallbladder carcinoma for the determination of tumor vascularity
    • Tian Y., Ding R.Y., Zhi Y.H., Guo R.X., and Wu S.D. Analysis of p53 and vascular endothelial growth factor expression in human gallbladder carcinoma for the determination of tumor vascularity. World J Gastroenterol 12 3 (2006) 415-419
    • (2006) World J Gastroenterol , vol.12 , Issue.3 , pp. 415-419
    • Tian, Y.1    Ding, R.Y.2    Zhi, Y.H.3    Guo, R.X.4    Wu, S.D.5
  • 84
    • 0031955262 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor correlates with tumor progression in gallbladder cancer
    • Okita S., Kondoh S., Shiraishi K., Kaino S., Hatano S., and Okita K. Expression of vascular endothelial growth factor correlates with tumor progression in gallbladder cancer. Int J Oncol 12 5 (1998) 1013-1018
    • (1998) Int J Oncol , vol.12 , Issue.5 , pp. 1013-1018
    • Okita, S.1    Kondoh, S.2    Shiraishi, K.3    Kaino, S.4    Hatano, S.5    Okita, K.6
  • 85
    • 0031858308 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in human gallbladder lesions
    • Yamamoto S., Fujii K., Kitadai Y., Yamamoto S., Tsuchida A., and Kajiyama G. Expression of vascular endothelial growth factor in human gallbladder lesions. Oncol Rep 5 5 (1998) 1065-1069
    • (1998) Oncol Rep , vol.5 , Issue.5 , pp. 1065-1069
    • Yamamoto, S.1    Fujii, K.2    Kitadai, Y.3    Yamamoto, S.4    Tsuchida, A.5    Kajiyama, G.6
  • 87
  • 89
    • 0037624602 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma
    • Tannapfel A., Sommerer F., Benicke M., Katalinic A., Uhlmann D., Witzigmann H., et al. Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma. Gut 52 5 (2003) 706-712
    • (2003) Gut , vol.52 , Issue.5 , pp. 706-712
    • Tannapfel, A.1    Sommerer, F.2    Benicke, M.3    Katalinic, A.4    Uhlmann, D.5    Witzigmann, H.6
  • 90
    • 0036016638 scopus 로고    scopus 로고
    • Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma
    • Isa T., Tomita S., Nakachi A., Miyazato H., Shimoji H., Kusano T., et al. Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma. Hepatogastroenterology 49 45 (2002) 604-608
    • (2002) Hepatogastroenterology , vol.49 , Issue.45 , pp. 604-608
    • Isa, T.1    Tomita, S.2    Nakachi, A.3    Miyazato, H.4    Shimoji, H.5    Kusano, T.6
  • 91
    • 0035675874 scopus 로고    scopus 로고
    • The expression of antiapoptotic proteins Bcl-2, Bcl-X(L), and Mcl-1 in benign, dysplastic, and malignant biliary epithelium
    • Okaro A.C., Deery A.R., Hutchins R.R., and Davidson B.R. The expression of antiapoptotic proteins Bcl-2, Bcl-X(L), and Mcl-1 in benign, dysplastic, and malignant biliary epithelium. J Clin Pathol 54 12 (2001) 927-932
    • (2001) J Clin Pathol , vol.54 , Issue.12 , pp. 927-932
    • Okaro, A.C.1    Deery, A.R.2    Hutchins, R.R.3    Davidson, B.R.4
  • 92
    • 0036786173 scopus 로고    scopus 로고
    • Pk11195, a mitochondrial benzodiazepine receptor antagonist, reduces apoptosis threshold in Bcl-X(L) and Mcl-1 expressing human cholangiocarcinoma cells
    • Okaro A.C., Fennell D.A., Corbo M., Davidson B.R., and Cotter F.E. Pk11195, a mitochondrial benzodiazepine receptor antagonist, reduces apoptosis threshold in Bcl-X(L) and Mcl-1 expressing human cholangiocarcinoma cells. Gut 51 4 (2002) 556-561
    • (2002) Gut , vol.51 , Issue.4 , pp. 556-561
    • Okaro, A.C.1    Fennell, D.A.2    Corbo, M.3    Davidson, B.R.4    Cotter, F.E.5
  • 93
    • 2442663096 scopus 로고    scopus 로고
    • Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells
    • Taniai M., Grambihler A., Higuchi H., Werneburg N., Bronk S.F., and Farrugia D. Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells. Cancer Res 64 10 (2004) 3517-3524
    • (2004) Cancer Res , vol.64 , Issue.10 , pp. 3517-3524
    • Taniai, M.1    Grambihler, A.2    Higuchi, H.3    Werneburg, N.4    Bronk, S.F.5    Farrugia, D.6
  • 95
    • 0036742764 scopus 로고    scopus 로고
    • Expression of G1-S modulators (p53, p16, p27, cyclin D1, Rb) and Smad4/Dpc4 in intrahepatic cholangiocarcinoma
    • Kang Y.K., Kim W.H., and Jang J.J. Expression of G1-S modulators (p53, p16, p27, cyclin D1, Rb) and Smad4/Dpc4 in intrahepatic cholangiocarcinoma. Human Pathol 33 9 (2002) 877-883
    • (2002) Human Pathol , vol.33 , Issue.9 , pp. 877-883
    • Kang, Y.K.1    Kim, W.H.2    Jang, J.J.3
  • 96
    • 0036771842 scopus 로고    scopus 로고
    • p16INK4a promoter mutations are frequent in primary sclerosing cholangitis (PSC) and PSC-associated cholangiocarcinoma
    • Taniai M., Grambihler A., Higuchi H., Werneburg N., Bronk S.F., Farrugia D., et al. p16INK4a promoter mutations are frequent in primary sclerosing cholangitis (PSC) and PSC-associated cholangiocarcinoma. Gastroenterology 123 4 (2002) 1090-1098
    • (2002) Gastroenterology , vol.123 , Issue.4 , pp. 1090-1098
    • Taniai, M.1    Grambihler, A.2    Higuchi, H.3    Werneburg, N.4    Bronk, S.F.5    Farrugia, D.6
  • 97
    • 0034945011 scopus 로고    scopus 로고
    • The role of overexpression and gene amplification of cyclin D1 in intrahepatic cholangiocarcinoma
    • Sugimachi K., Aishima S., Taguchi K., Tanaka S., Shimada M., Kajiyama K., et al. The role of overexpression and gene amplification of cyclin D1 in intrahepatic cholangiocarcinoma. J Hepatol 35 1 (2001) 74-79
    • (2001) J Hepatol , vol.35 , Issue.1 , pp. 74-79
    • Sugimachi, K.1    Aishima, S.2    Taguchi, K.3    Tanaka, S.4    Shimada, M.5    Kajiyama, K.6
  • 99
    • 0035836286 scopus 로고    scopus 로고
    • Genotyping of multiple genetic alterations of intrahepatic cholangiocarcinoma
    • Cong W., Wu M., and Chen H. Genotyping of multiple genetic alterations of intrahepatic cholangiocarcinoma. Zhonghua Yi Xue Za Zhi 81 5 (2001) 271-273
    • (2001) Zhonghua Yi Xue Za Zhi , vol.81 , Issue.5 , pp. 271-273
    • Cong, W.1    Wu, M.2    Chen, H.3
  • 100
    • 0035688284 scopus 로고    scopus 로고
    • Alpha-particle carcinogenesis in Thorotrast patients: epidemiology, dosimetry, pathology, and molecular analysis
    • Ishikawa Y., Wada I., and Fukumoto M. Alpha-particle carcinogenesis in Thorotrast patients: epidemiology, dosimetry, pathology, and molecular analysis. J Environ Pathol Toxicol Oncol 20 4 (2001) 311-315
    • (2001) J Environ Pathol Toxicol Oncol , vol.20 , Issue.4 , pp. 311-315
    • Ishikawa, Y.1    Wada, I.2    Fukumoto, M.3
  • 102
    • 0345369550 scopus 로고    scopus 로고
    • Mutation of p53 and K-ras, and loss of heterozygosity of APC in intrahepatic cholangiocarcinoma
    • Kang Y.K., Kim W.H., Lee H.W., Lee H.K., and Kim Y.I. Mutation of p53 and K-ras, and loss of heterozygosity of APC in intrahepatic cholangiocarcinoma. Lab Invest 79 4 (1999) 477-483
    • (1999) Lab Invest , vol.79 , Issue.4 , pp. 477-483
    • Kang, Y.K.1    Kim, W.H.2    Lee, H.W.3    Lee, H.K.4    Kim, Y.I.5
  • 103
    • 0033809007 scopus 로고    scopus 로고
    • Allelic loss in human intrahepatic cholangiocarcinoma: correlation between chromosome 8p22 and tumor progression
    • Kawaki J., Miyazaki M., Ito H., Nakagawa K., Shimizu H., Yoshidome H., et al. Allelic loss in human intrahepatic cholangiocarcinoma: correlation between chromosome 8p22 and tumor progression. Int J Cancer 88 2 (2000) 228-231
    • (2000) Int J Cancer , vol.88 , Issue.2 , pp. 228-231
    • Kawaki, J.1    Miyazaki, M.2    Ito, H.3    Nakagawa, K.4    Shimizu, H.5    Yoshidome, H.6
  • 104
    • 0034534986 scopus 로고    scopus 로고
    • No consistent pattern of mutations in p53 and ras genes in liver tumors of rat treated with the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)
    • Komulainen H., Hakulinen P., Servomaa K., Makkonen K., Vasara R., Maki-Paakkanen J., et al. No consistent pattern of mutations in p53 and ras genes in liver tumors of rat treated with the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX). Environ Mol Mutagen 36 4 (2000) 292-300
    • (2000) Environ Mol Mutagen , vol.36 , Issue.4 , pp. 292-300
    • Komulainen, H.1    Hakulinen, P.2    Servomaa, K.3    Makkonen, K.4    Vasara, R.5    Maki-Paakkanen, J.6
  • 105
    • 2942530868 scopus 로고    scopus 로고
    • Serum and bile markers for cholangiocarcinoma
    • Nehls O., Gregor M., and Klump B. Serum and bile markers for cholangiocarcinoma. Semin Liver Dis 24 2 (2004) 139-154
    • (2004) Semin Liver Dis , vol.24 , Issue.2 , pp. 139-154
    • Nehls, O.1    Gregor, M.2    Klump, B.3
  • 107
    • 0032951925 scopus 로고    scopus 로고
    • Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: a link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma
    • Radaeva S., Ferreira-Gonzalez A., and Sirica A.E. Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: a link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma. Hepatology 29 5 (1999) 1453-1462
    • (1999) Hepatology , vol.29 , Issue.5 , pp. 1453-1462
    • Radaeva, S.1    Ferreira-Gonzalez, A.2    Sirica, A.E.3
  • 108
    • 0037373855 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells
    • Benckert C., Jonas S., Cramer T., Von Marschall Z., Schafer G., Peters M., et al. Transforming growth factor beta 1 stimulates vascular endothelial growth factor gene transcription in human cholangiocellular carcinoma cells. Cancer Res 63 5 (2003) 1083-1092
    • (2003) Cancer Res , vol.63 , Issue.5 , pp. 1083-1092
    • Benckert, C.1    Jonas, S.2    Cramer, T.3    Von Marschall, Z.4    Schafer, G.5    Peters, M.6
  • 109
    • 0032577204 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 stimulates or inhibits cell growth via down- or up-regulation of p21/Waf1
    • Miyasaka K., Kabashima T., Hamaguchi H., Hanada T., Mitsunaga K., Maejima S., et al. Transforming growth factor-beta 1 stimulates or inhibits cell growth via down- or up-regulation of p21/Waf1. Biochem Biophys Res Commun 246 3 (1998) 873-880
    • (1998) Biochem Biophys Res Commun , vol.246 , Issue.3 , pp. 873-880
    • Miyasaka, K.1    Kabashima, T.2    Hamaguchi, H.3    Hanada, T.4    Mitsunaga, K.5    Maejima, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.