Discovering severe acute respiratory syndrome coronavirus 3CL protease inhibitors: Virtual screening, surface plasmon resonance, and fluorescence resonance energy transfer assays

Journal of Biomolecular Screening

Volumn 11, Issue 8, 2006, Pages 915-921

  Chen, Lili ^a   Chen, Shuai ^a   Gui, Chunshan ^a   Shen, Jianhua ^a   Shen, Xu ^a,b   Jiang, Hualiang ^a,b  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

FRET; Inhibitor; SARS; SARS CoV 3CL pro; SPR; Virtual screening

Indexed keywords

ENZYME INHIBITOR; PROTEINASE INHIBITOR; SARS CORONAVIRUS 3C LIKE PROTEASE; VIRUS ENZYME;

ARTICLE; CONTROLLED STUDY; DATA BASE; DISSOCIATION CONSTANT; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME BINDING; FLUORESCENCE ANALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; IC 50; NONHUMAN; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROTEINASE INHIBITION; RELIABILITY; SARS CORONAVIRUS; SCREENING; SURFACE PLASMON RESONANCE; VIRTUAL SCREENING;

BINDING SITES; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FLUORESCENCE RESONANCE ENERGY TRANSFER; MOLECULAR STRUCTURE; PROTEASE INHIBITORS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SARS VIRUS; SURFACE PLASMON RESONANCE; VIRAL PROTEINS;

SARS CORONAVIRUS;

EID: 33751577809     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057106293295     Document Type: Article

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