Enzymatic activity characterization of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer technique

Acta Pharmacologica Sinica

Volumn 26, Issue 1, 2005, Pages 99-106

  Chen, Shuai ^a   Chen, Li Li ^a   Luo, Hai Bin ^a   Sun, Tao ^a   Chen, Jing ^a   Ye, Fei ^a   Cai, Jian Hua ^a   Shen, Jing Kang ^a   Shen, Xu ^a   Jiang, Hua Liang ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

3C like protease; Enzyme activity; Fluorescence resonance energy transfer; Fluorogenic substrate; Severe acute respiratory coronavirus; Site directed mutagenesis

Indexed keywords

ALANINE; CYSTEINE; HISTIDINE; METHIONINE; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 3C LIKE PROTEASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME KINETICS; FLUORESCENCE RESONANCE ENERGY TRANSFER; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PROTEIN DEGRADATION; SARS CORONAVIRUS; SITE DIRECTED MUTAGENESIS; TEMPERATURE; VIRUS MUTANT;

ALANINE; AMINO ACID SUBSTITUTION; CYSTEINE; CYSTEINE ENDOPEPTIDASES; ENDOPEPTIDASES; FLUORESCENCE RESONANCE ENERGY TRANSFER; HISTIDINE; HYDROGEN-ION CONCENTRATION; KINETICS; METHIONINE; MUTAGENESIS, SITE-DIRECTED; SARS VIRUS; SUBSTRATE SPECIFICITY; TEMPERATURE; VIRAL PROTEINS;

EID: 19944427356     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2005.00010.x     Document Type: Article

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