Noninvasive Cortical Stimulation in Neurorehabilitation: A Review

Archives of Physical Medicine and Rehabilitation

Volumn 87, Issue 12 SUPPL., 2006, Pages 84-93

  Harris Love, Michelle L ^a   Cohen, Leonardo G ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Neuronal plasticity; Rehabilitation; Transcranial magnetic stimulation

Indexed keywords

ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; BRAIN DEPTH STIMULATION; BRAIN MAPPING; BRAIN REGION; DOWN REGULATION; HEMISPHERE; HUMAN; MOTOR PERFORMANCE; MOTOR SYSTEM; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NERVOUS SYSTEM INJURY; NEUROIMAGING; POSITRON EMISSION TOMOGRAPHY; STROKE; TRAINING; TRANSCRANIAL MAGNETIC STIMULATION;

CEREBRAL CORTEX; CEREBROVASCULAR ACCIDENT; DIAGNOSTIC IMAGING; HUMANS; MOTOR SKILLS DISORDERS; NEURONAL PLASTICITY; RECOVERY OF FUNCTION; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 33751405353     PISSN: 00039993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apmr.2006.08.330     Document Type: Article

References (150)

1. Gandiga P.C., Hummel F.C., and Cohen L.G. Transcranial DC stimulation (tDCS): a tool for double-blind sham-controlled clinical studies in brain stimulation. Clin Neurophysiol 117 (2006) 845-850
2. Roth B.J., Saypol J.M., Hallett M., and Cohen L.G. A theoretical calculation of the electric field induced in the cortex during magnetic stimulation. Electroencephalogr Clin Neurophysiol 81 (1991) 47-56
3. Day B.L., Dressler D., Maertens de Noordhout A., et al. Electric and magnetic stimulation of human motor cortex: surface EMG and single motor unit responses. [published erratum in: J Physiol (Lond) 1990;430:617]. J Physiol 412 (1989) 449-473
4. Cohen L.G., Roth B.J., Wassermann E.M., et al. Magnetic stimulation of the human cerebral cortex, an indicator of reorganization in motor pathways in certain pathological conditions. J Clin Neurophysiol 8 (1991) 56-65
5. Chen R., Lozano A.M., and Ashby P. Mechanism of the silent period following transcranial magnetic stimulation. Evidence from epidural recordings. Exp Brain Res 128 (1999) 539-542
6. Chen R., Yung D., and Li J.Y. Organization of ipsilateral excitatory and inhibitory pathways in the human motor cortex. J Neurophysiol 89 (2003) 1256-1264
7. Garvey M.A., Ziemann U., Becker D.A., Barker C.A., and Bartko J.J. New graphical method to measure silent periods evoked by transcranial magnetic stimulation. Clin Neurophysiol 112 (2001) 1451-1460
8. Boroojerdi B., Hungs M., Mull M., Topper R., and Noth J. Interhemispheric inhibition in patients with multiple sclerosis. Electroencephalogr Clin Neurophysiol 109 (1998) 230-237
9. Meyer B.U., Roricht S., Schmierer K., et al. First diagnostic applications of transcallosal inhibition in diseases affecting callosal neurones (multiple sclerosis, hydrocephalus, Huntington's disease). Electroencephalogr Clin Neurophysiol Suppl 51 (1999) 233-242
10. Schmierer K., Irlbacher K., Grosse P., Roricht S., and Meyer B.U. Correlates of disability in multiple sclerosis detected by transcranial magnetic stimulation. Neurology 59 (2002) 1218-1224
11. Bajbouj M., Gallinat J., Niehaus L., Lang U.E., Roricht S., and Meyer B.U. Abnormalities of inhibitory neuronal mechanisms in the motor cortex of patients with schizophrenia. Pharmacopsychiatry 37 (2004) 74-80
12. Boroojerdi B., Topper R., Foltys H., and Meincke U. Transcallosal inhibition and motor conduction studies in patients with schizophrenia using transcranial magnetic stimulation. Br J Psychiatry 175 (1999) 375-379
13. Niehaus L., von Alt-Stutterheim K., Roricht S., and Meyer B.U. Abnormal postexcitatory and interhemispheric motor cortex inhibition in writer's cramp. J Neurol 248 (2001) 51-56
14. Wolters A., Classen J., Kunesch E., Grossmann A., and Benecke R. Measurements of transcallosally mediated cortical inhibition for differentiating parkinsonian syndromes. Mov Disord 19 (2004) 518-528
15. Garvey M.A., Barker C.A., Bartko J.J., et al. The ipsilateral silent period in boys with attention-deficit/hyperactivity disorder. Clin Neurophysiol 116 (2005) 1889-1896
16. Day B.L., Rothwell J.C., Thompson P.D., et al. Delay in the execution of voluntary movement by electrical or magnetic brain stimulation in intact man. Evidence for the storage of motor programs in the brain. Brain 112 Pt 3 (1989) 649-663
17. Amassian V.E., Cracco R.Q., Maccabee P.J., Cracco J.B., Rudell A., and Eberle L. Suppression of visual perception by magnetic coil stimulation of human occipital cortex. Electroencephalogr Clin Neurophysiol 74 (1989) 458-462
18. Walsh V., and Rushworth M. A primer of magnetic stimulation as a tool for neuropsychology. Neuropsychologia 37 (1999) 125-135
19. Kujirai T., Caramia M.D., Rothwell J.C., et al. Corticocortical inhibition in human motor cortex. J Physiol 471 (1993) 501-519
20. Ferbert A., Priori A., Rothwell J.C., Day B.L., Colebatch J.G., and Marsden C.D. Interhemispheric inhibition of the human motor cortex. J Physiol 453 (1992) 525-546
21. Baumer T., Bock F., Koch G., et al. Magnetic stimulation of human premotor or motor cortex produces interhemispheric facilitation through distinct pathways. J Physiol 572 Pt 3 (2006) 857-868
22. Hanajima R., Ugawa Y., Machii K., et al. Interhemispheric facilitation of the hand motor area in humans. J Physiol 531 Pt 3 (2001) 849-859
23. Ugawa Y., Hanajima R., and Kanazawa I. Interhemispheric facilitation of the hand area of the human motor cortex. Neurosci Lett 160 (1993) 153-155
24. Claus D., Weis M., Jahnke U., Plewe A., and Brunholzl C. Corticospinal conduction studied with magnetic double stimulation in the intact human. J Neurol Sci 111 (1992) 180-188
25. Nakamura H., Kitagawa H., Kawaguchi Y., and Tsuji H. Intracortical facilitation and inhibition after transcranial magnetic stimulation in conscious humans. J Physiol 498 Pt 3 (1997) 817-823
26. Nakamura H., Kitagawa H., Kawaguchi Y., Tsuji H., Takano H., and Nakatoh S. Intracortical facilitation and inhibition after paired magnetic stimulation in humans under anesthesia. Neurosci Lett 199 (1995) 155-157
27. Sanger T.D., Garg R.R., and Chen R. Interactions between two different inhibitory systems in the human motor cortex. J Physiol 530 Pt 2 (2001) 307-317
28. Werhahn K.J., Kunesch E., Noachtar S., Benecke R., and Classen J. Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans. J Physiol 517 Pt 2 (1999) 591-597
29. Ziemann U., Lonnecker S., and Paulus W. Inhibition of human motor cortex by ethanol. A transcranial magnetic stimulation study. Brain 118 Pt 6 (1995) 1437-1446
30. Liepert J., Schwenkreis P., Tegenthoff M., and Malin J.P. The glutamate antagonist riluzole suppresses intracortical facilitation. J Neural Transm 104 (1997) 1207-1214
31. Schwenkreis P., Liepert J., Witscher K., et al. Riluzole suppresses motor cortex facilitation in correlation to its plasma level. A study using transcranial magnetic stimulation. Exp Brain Res 135 (2000) 293-299
32. Daskalakis Z.J., Christensen B.K., Chen R., Fitzgerald P.B., Zipursky R.B., and Kapur S. Evidence for impaired cortical inhibition in schizophrenia using transcranial magnetic stimulation. Arch Gen Psychiatry 59 (2002) 347-354
33. Hanajima R., Ugawa Y., Okabe S., et al. Interhemispheric interaction between the hand motor areas in patients with cortical myoclonus. Clin Neurophysiol 112 (2001) 623-626
34. Daskalakis Z.J., Christensen B.K., Fitzgerald P.B., Roshan L., and Chen R. The mechanisms of interhemispheric inhibition in the human motor cortex. J Physiol 543 Pt 1 (2002) 317-326
35. Duque J., Hummel F., Celnik P., Murase N., Mazzocchio R., and Cohen L.G. Transcallosal inhibition in chronic subcortical stroke. Neuroimage 28 (2005) 940-946
36. Duque J., Mazzocchio R., Dambrosia J., Murase N., Olivier E., and Cohen L.G. Kinematically specific interhemispheric inhibition operating in the process of generation of a voluntary movement. Cereb Cortex 15 (2005) 588-593
37. Murase N., Duque J., Mazzocchio R., and Cohen L.G. Influence of interhemispheric interactions on motor function in chronic subcortical stroke. Ann Neurol 55 (2004) 400-409
38. Pascual-Leone A., Tormos J.M., Keenan J., Tarazona F., Canete C., and Catala M.D. Study and modulation of human cortical excitability with transcranial magnetic stimulation. J Clin Neurophysiol 15 (1998) 333-343
39. Chen R., Classen J., Gerloff C., et al. Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation. Neurology 48 (1997) 1398-1403
40. Muellbacher W., Ziemann U., Boroojerdi B., and Hallett M. Effects of low-frequency transcranial magnetic stimulation on motor excitability and basic motor behavior. Clin Neurophysiol 111 (2000) 1002-1007
41. Pascual-Leone A., Valls-Sole J., Wassermann E.M., and Hallett M. Responses to rapid-rate transcranial magnetic stimulation of the human motor cortex. Brain 117 Pt 4 (1994) 847-858
42. Evers S., Bockermann I., and Nyhuis P.W. The impact of transcranial magnetic stimulation on cognitive processing: an event-related potential study. Neuroreport 17 12 (2001) 2915-2918
43. Hadland K.A., Rushworth M.F., Passingham R.E., Jahanshahi M., and Rothwell J.C. Interference with performance of a response selection task that has no working memory component: an rTMS comparison of the dorsolateral prefrontal and medial frontal cortex. J Cogn Neurosci 13 (2001) 1097-1108
44. Amedi A., Floel A., Knecht S., Zohary E., and Cohen L.G. Transcranial magnetic stimulation of the occipital pole interferes with verbal processing in blind subjects. Nat Neurosci 7 (2004) 1266-1270
45. Cohen L.G., Celnik P., Pascual-Leone A., et al. Functional relevance of cross-modal plasticity in blind humans. Nature 389 (1997) 180-183
46. MacDonald P.A., and Paus T. The role of parietal cortex in awareness of self-generated movements: a transcranial magnetic stimulation study. Cereb Cortex 13 (2003) 962-967
47. Pal P.K., Hanajima R., Gunraj C.A., et al. Effect of low-frequency repetitive transcranial magnetic stimulation on interhemispheric inhibition. J Neurophysiol 94 (2005) 1668-1675
48. Butefisch C.M., Khurana V., Kopylev L., and Cohen L.G. Enhancing encoding of a motor memory in the primary motor cortex by cortical stimulation. J Neurophysiol 91 (2004) 2110-2116
49. Padberg F., Zwanzger P., Keck M.E., et al. Repetitive transcranial magnetic stimulation (rTMS) in major depression: relation between efficacy and stimulation intensity. Neuropsychopharmacology 27 (2002) 638-645
50. Lefaucheur J.P., Drouot X., Von Raison F., Menard-Lefaucheur I., Cesaro P., and Nguyen J.P. Improvement of motor performance and modulation of cortical excitability by repetitive transcranial magnetic stimulation of the motor cortex in Parkinson's disease. Clin Neurophysiol 115 (2004) 2530-2541
51. Siebner H.R., Tormos J.M., Ceballos-Baumann A.O., et al. Low-frequency repetitive transcranial magnetic stimulation of the motor cortex in writer's cramp. Neurology 52 (1999) 529-537
52. Khedr E.M., Ahmed M.A., Fathy N., and Rothwell J.C. Therapeutic trial of repetitive transcranial magnetic stimulation after acute ischemic stroke. Neurology 65 (2005) 466-468
53. Mansur C.G., Fregni F., Boggio P.S., et al. A sham stimulation-controlled trial of rTMS of the unaffected hemisphere in stroke patients. Neurology 64 (2005) 1802-1804
54. Kobayashi M., Hutchinson S., Theoret H., Schlaug G., and Pascual-Leone A. Repetitive TMS of the motor cortex improves ipsilateral sequential simple finger movements. Neurology 62 (2004) 91-98
55. Hess G., Aizenman C.D., and Donoghue J.P. Conditions for the induction of long-term potentiation in layer II/III horizontal connections of the rat motor cortex. J Neurophysiol 75 (1996) 1765-1778
56. Larson J., Wong D., and Lynch G. Patterned stimulation at the theta frequency is optimal for the induction of hippocampal long-term potentiation. Brain Res 368 (1986) 347-350
57. Hess G., and Donoghue J.P. Long-term depression of horizontal connections in rat motor cortex. Eur J Neurosci 8 (1996) 658-665
58. Huang Y.Z., Edwards M.J., Rounis E., Bhatia K.P., and Rothwell J.C. Theta burst stimulation of the human motor cortex. Neuron 45 (2005) 201-206
59. Nitsche M.A., Niehaus L., Hoffmann K.T., et al. MRI study of human brain exposed to weak direct current stimulation of the frontal cortex. Clin Neurophysiol 115 (2004) 2419-2423
60. Nitsche M.A., Nitsche M.S., Klein C.C., Tergau F., Rothwell J.C., and Paulus W. Level of action of cathodal DC polarisation induced inhibition of the human motor cortex. Clin Neurophysiol 114 (2003) 600-604
61. Elbert T., Lutzenberger W., Rockstroh B., and Birbaumer N. The influence of low-level transcortical DC-currents on response speed in humans. Int J Neurosci 14 (1981) 101-114
62. Fregni F., Boggio P.S., Nitsche M., et al. Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Exp Brain Res 166 (2005) 23-30
63. Kincses T.Z., Antal A., Nitsche M.A., Bartfai O., and Paulus W. Facilitation of probabilistic classification learning by transcranial direct current stimulation of the prefrontal cortex in the human. Neuropsychologia 42 (2004) 113-117
64. Marshall L., Molle M., Hallschmid M., and Born J. Transcranial direct current stimulation during sleep improves declarative memory. J Neurosci 24 (2004) 9985-9992
65. Nitsche M.A., and Paulus W. Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J Physiol 527 Pt 3 (2000) 633-639
66. Nitsche M.A., and Paulus W. Sustained excitability elevations induced by transcranial DC motor cortex stimulation in humans. Neurology 57 (2001) 1899-1901
67. Liebetanz D., Nitsche M.A., Tergau F., and Paulus W. Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability. Brain 125 Pt 10 (2002) 2238-2247
68. Nitsche M.A., Fricke K., Henschke U., et al. Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans. J Physiol 553 Pt 1 (2003) 293-301
69. Nitsche M.A., Seeber A., Frommann K., et al. Modulating parameters of excitability during and after transcranial direct current stimulation of the human motor cortex. J Physiol 568 Pt 1 (2005) 291-303
70. Hummel F.C., and Cohen L.G. Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?. Lancet Neurol 5 (2006) 708-712
71. Quartarone A., Morgante F., Bagnato S., et al. Long lasting effects of transcranial direct current stimulation on motor imagery. Neuroreport 15 (2004) 1287-1291
72. Rosenkranz K., Nitsche M.A., Tergau F., and Paulus W. Diminution of training-induced transient motor cortex plasticity by weak transcranial direct current stimulation in the human. Neurosci Lett 296 (2000) 61-63
73. Nitsche M.A., Schauenburg A., Lang N., et al. Facilitation of implicit motor learning by weak transcranial direct current stimulation of the primary motor cortex in the human. J Cogn Neurosci 15 (2003) 619-626
74. Antal A., Nitsche M.A., Kincses T.Z., Kruse W., Hoffmann K.P., and Paulus W. Facilitation of visuo-motor learning by transcranial direct current stimulation of the motor and extrastriate visual areas in humans. Eur J Neurosci May 19 (2004) 2888-2892
75. Antal A., Nitsche M.A., Kruse W., Kincses T.Z., Hoffmann K.P., and Paulus W. Direct current stimulation over V5 enhances visuomotor coordination by improving motion perception in humans. J Cogn Neurosci 16 (2004) 521-527
76. Uy J., and Ridding M.C. Increased cortical excitability induced by transcranial DC and peripheral nerve stimulation. J Neurosci Methods 127 (2003) 193-197
77. Lang N., Siebner H.R., Ernst D., et al. Preconditioning with transcranial direct current stimulation sensitizes the motor cortex to rapid-rate transcranial magnetic stimulation and controls the direction of after-effects. Biol Psychiatry 56 (2004) 634-639
78. Siebner H.R., Lang N., Rizzo V., et al. Preconditioning of low-frequency repetitive transcranial magnetic stimulation with transcranial direct current stimulation: evidence for homeostatic plasticity in the human motor cortex. J Neurosci 24 (2004) 3379-3385
79. Hummel F., Celnik P., Giraux P., et al. Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke. Brain 128 Pt 3 (2005) 490-499
80. Hummel F., and Cohen L.G. Improvement of motor function with noninvasive cortical stimulation in a patient with chronic stroke. Neurorehabil Neural Repair 19 (2005) 14-19
81. Plewnia C., Lotze M., and Gerloff C. Disinhibition of the contralateral motor cortex by low-frequency rTMS. Neuroreport 14 (2003) 609-612
82. Michael N., Gosling M., Reutemann M., et al. Metabolic changes after repetitive transcranial magnetic stimulation (rTMS) of the left prefrontal cortex: a sham-controlled proton magnetic resonance spectroscopy (1H MRS) study of healthy brain. Eur J Neurosci 17 (2003) 2462-2468
83. Bestmann S., Baudewig J., Siebner H.R., Rothwell J.C., and Frahm J. Functional MRI of the immediate impact of transcranial magnetic stimulation on cortical and subcortical motor circuits. Eur J Neurosci 19 (2004) 1950-1962
84. Lang N., Siebner H.R., Ward N.S., et al. How does transcranial DC stimulation of the primary motor cortex alter regional neuronal activity in the human brain?. Eur J Neurosci 22 (2005) 495-504
85. Strens L.H., Fogelson N., Shanahan P., Rothwell J.C., and Brown P. The ipsilateral human motor cortex can functionally compensate for acute contralateral motor cortex dysfunction. Curr Biol 13 (2003) 1201-1205
86. Sack A.T., Camprodon J.A., Pascual-Leone A., and Goebel R. The dynamics of interhemispheric compensatory processes in mental imagery. Science 308 (2005) 702-704
87. Glover S., Miall R.C., and Rushworth M.F. Parietal rTMS disrupts the initiation but not the execution of on-line adjustments to a perturbation of object size. J Cogn Neurosci 17 (2005) 124-136
88. Werhahn K.J., Conforto A.B., Kadom N., Hallett M., and Cohen L.G. Contribution of the ipsilateral motor cortex to recovery after chronic stroke. Ann Neurol 54 (2003) 464-472
89. Ganis G., Keenan J.P., Kosslyn S.M., and Pascual-Leone A. Transcranial magnetic stimulation of primary motor cortex affects mental rotation. Cereb Cortex 10 (2000) 175-180
90. Mull B.R., and Seyal M. Transcranial magnetic stimulation of left prefrontal cortex impairs working memory. Clin Neurophysiol 112 (2001) 1672-1675
91. Fregni F., Boggio P.S., Mansur C.G., et al. Transcranial direct current stimulation of the unaffected hemisphere in stroke patients. Neuroreport 16 (2005) 1551-1555
92. Turner M.R., Osei-Lah A.D., Hammers A., et al. Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS. J Neurol Neurosurg Psychiatry 76 (2005) 1279-1285
93. Hamer H.M., Reis J., Mueller H.H., et al. Motor cortex excitability in focal epilepsies not including the primary motor area-a TMS study. Brain 128 Pt 4 (2005) 811-818
94. Pierantozzi M., Panella M., Palmieri M.G., et al. Different TMS patterns of intracortical inhibition in early onset Alzheimer dementia and frontotemporal dementia. Clin Neurophysiol 115 (2004) 2410-2418
95. Brighina F., Scalia S., Gennuso M., et al. Hypo-excitability of cortical areas in patients affected by Friedreich ataxia: a TMS study. J Neurol Sci 235 (2005) 19-22
96. Aurora S.K., Barrodale P., Chronicle E.P., and Mulleners W.M. Cortical inhibition is reduced in chronic and episodic migraine and demonstrates a spectrum of illness. Headache 45 (2005) 546-552
97. Attarian S., Azulay J.P., Lardillier D., Verschueren A., and Pouget J. Transcranial magnetic stimulation in lower motor neuron diseases. Clin Neurophysiol 116 (2005) 35-42
98. Koski L., Mernar T.J., and Dobkin B.H. Immediate and long-term changes in corticomotor output in response to rehabilitation: correlation with functional improvements in chronic stroke. Neurorehabil Neural Repair 18 (2004) 230-249
99. Liepert J., Graef S., Uhde I., Leidner O., and Weiller C. Training-induced changes of motor cortex representations in stroke patients. Acta Neurol Scand 101 (2000) 321-326
100. Liepert J., Miltner W.H., Bauder H., et al. Motor cortex plasticity during constraint-induced movement therapy in stroke patients. Neurosci Lett 250 (1998) 5-8
101. Park S.W., Butler A.J., Cavalheiro V., Alberts J.L., and Wolf S.L. Changes in serial optical topography and TMS during task performance after constraint-induced movement therapy in stroke: a case study. Neurorehabil Neural Repair 18 (2004) 95-105
102. Ward N.S., and Cohen L.G. Mechanisms underlying recovery of motor function after stroke. Arch Neurol 61 (2004) 1844-1848
103. Xerri C., Merzenich M.M., Peterson B.E., and Jenkins W. Plasticity of primary somatosensory cortex paralleling sensorimotor skill recovery from stroke in adult monkeys. J Neurophysiol 79 (1998) 2119-2148
104. Jones T.A., Kleim J.A., and Greenough W.T. Synaptogenesis and dendritic growth in the cortex opposite unilateral sensorimotor cortex damage in adult rats: a quantitative electron microscopic examination. Brain Res 733 (1996) 142-148
105. Neumann-Haefelin T., and Witte O.W. Periinfarct and remote excitability changes after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 20 (2000) 45-52
106. Hicks S.P., and D'Amato C.J. Motor-sensory and visual behavior after hemispherectomy in newborn and mature rats. Exp Neurol 29 (1970) 416-438
107. Chen R., Gerloff C., Hallett M., and Cohen L.G. Involvement of the ipsilateral motor cortex in finger movements of different complexities. Ann Neurol 41 (1997) 247-254
108. Calautti C., and Baron J.C. Functional neuroimaging studies of motor recovery after stroke in adults: a review. Stroke 34 (2003) 1553-1566
109. Cramer S.C. Stroke recovery. Lessons from functional MR imaging and other methods of human brain mapping. Phys Med Rehabil Clin N Am 10 (1999) 875-886
110. Cramer S.C., Nelles G., Benson R.R., et al. A functional MRI study of subjects recovered from hemiparetic stroke. Stroke 28 (1997) 2518-2527
111. Ward N.S., Brown M.M., Thompson A.J., and Frackowiak R.S. Neural correlates of outcome after stroke: a cross-sectional fMRI study. Brain 126 Pt 6 (2003) 1430-1448
112. Ward N.S., Brown M.M., Thompson A.J., and Frackowiak R.S. Neural correlates of motor recovery after stroke: a longitudinal fMRI study. Brain 126 Pt 11 (2003) 2476-2496
113. Small S.L., Hlustik P., Noll D.C., Genovese C., and Solodkin A. Cerebellar hemispheric activation ipsilateral to the paretic hand correlates with functional recovery after stroke. Brain 125 Pt 7 (2002) 1544-1557
114. Kim Y.H., Jang S.H., Byun W.M., Han B.S., Lee K.H., and Ahn S.H. Ipsilateral motor pathway confirmed by combined brain mapping of a patient with hemiparetic stroke: a case report. Arch Phys Med Rehabil 85 (2004) 1351-1353
115. Muellbacher W., Artner C., and Mamoli B. The role of the intact hemisphere in recovery of midline muscles after recent monohemispheric stroke. J Neurol 246 (1999) 250-256
116. Butefisch C.M., Netz J., Wessling M., Seitz R.J., and Homberg V. Remote changes in cortical excitability after stroke. Brain 126 Pt 2 (2003) 470-481
117. Gerloff C., Bushara K., Sailer A., et al. Multimodal imaging of brain reorganization in motor areas of the contralesional hemisphere of well recovered patients after capsular stroke. Brain 129 Pt 3 (2006) 791-808
118. Johansen-Berg H., Rushworth M.F., Bogdanovic M.D., Kischka U., Wimalaratna S., and Matthews P.M. The role of ipsilateral premotor cortex in hand movement after stroke. Proc Natl Acad Sci U S A 99 (2002) 14518-14523
119. Lotze M., Markert J., Sauseng P., Hoppe J., Plewnia C., and Gerloff C. The role of multiple contralesional motor areas for complex hand movements after internal capsular lesion. J Neurosci 26 (2006) 6096-6102
120. Foltys H., Krings T., Meister I.G., et al. Motor representation in patients rapidly recovering after stroke: a functional magnetic resonance imaging and transcranial magnetic stimulation study. Clin Neurophysiol 114 (2003) 2404-2415
121. Turton A., Wroe S., Trepte N., Fraser C., and Lemon R.N. Contralateral and ipsilateral EMG responses to transcranial magnetic stimulation during recovery of arm and hand function after stroke. Electroencephalogr Clin Neurophysiol 101 (1996) 316-328
122. Fridman E.A., Hanakawa T., Chung M., Hummel F., Leiguarda R.C., and Cohen L.G. Reorganization of the human ipsilesional premotor cortex after stroke. Brain 127 Pt 4 (2004) 747-758
123. Friel K.M., Heddings A.A., and Nudo R.J. Effects of postlesion experience on behavioral recovery and neurophysiologic reorganization after cortical injury in primates. Neurorehabil Neural Repair 14 (2000) 187-198
124. Nudo R.J., Plautz E.J., and Frost S.B. Role of adaptive plasticity in recovery of function after damage to motor cortex. Muscle Nerve 24 (2001) 1000-1019
125. Jaillard A., Martin C.D., Garambois K., Lebas J.F., and Hommel M. Vicarious function within the human primary motor cortex?. A longitudinal fMRI stroke study. Brain 128 Pt 5 (2005) 1122-1138
126. Seitz R.J., Butefisch C.M., Kleiser R., and Homberg V. Reorganisation of cerebral circuits in human ischemic brain disease. Restor Neurol Neurosci 22 (2004) 207-229
127. Butefisch C.M., Kleiser R., Korber B., et al. Recruitment of contralesional motor cortex in stroke patients with recovery of hand function. Neurology 64 (2005) 1067-1069
128. Liepert J., Hamzei F., and Weiller C. Motor cortex disinhibition of the unaffected hemisphere after acute stroke. Muscle Nerve 23 (2000) 1761-1763
129. Shimizu T., Hosaki A., Hino T., et al. Motor cortical disinhibition in the unaffected hemisphere after unilateral cortical stroke. Brain 125 Pt 8 (2002) 1896-1907
130. Martin P.I., Naeser M.A., Theoret H., et al. Transcranial magnetic stimulation as a complementary treatment for aphasia. Semin Speech Lang 25 (2004) 181-191
131. Winhuisen L., Thiel A., Schumacher B., et al. Role of the contralateral inferior frontal gyrus in recovery of language function in poststroke aphasia: a combined repetitive transcranial magnetic stimulation and positron emission tomography study. Stroke 36 (2005) 1759-1763
132. Traversa R., Cicinelli P., Bassi A., Rossini P.M., and Bernardi G. Mapping of motor cortical reorganization after stroke. A brain stimulation study with focal magnetic pulses. Stroke 28 (1997) 110-117
133. Luft A.R., McCombe-Waller S., Whitall J., et al. Repetitive bilateral arm training and motor cortex activation in chronic stroke: a randomized controlled trial [published erratum in: JAMA 2004;292:2470]. JAMA 292 (2004) 1853-1861
134. Rau C., Plewnia C., Hummel F., and Gerloff C. Event-related desynchronization and excitability of the ipsilateral motor cortex during simple self-paced finger movements. Clin Neurophysiol 114 (2003) 1819-1826
135. Cicinelli P., Traversa R., and Rossini P.M. Post-stroke reorganization of brain motor output to the hand: a 2-4 month follow-up with focal magnetic transcranial stimulation. Electroencephalogr Clin Neurophysiol 105 (1997) 438-450
136. Traversa R., Cicinelli P., Oliveri M., et al. Neurophysiological follow-up of motor cortical output in stroke patients. Clin Neurophysiol 111 (2000) 1695-1703
137. Traversa R., Cicinelli P., Pasqualetti P., Filippi M., and Rossini P.M. Follow-up of interhemispheric differences of motor evoked potentials from the 'affected' and 'unaffected' hemispheres in human stroke. Brain Res 803 (1998) 1-8
138. Liepert J., Storch P., Fritsch A., and Weiller C. Motor cortex disinhibition in acute stroke. Clin Neurophysiol 111 (2000) 671-676
139. Liepert J., Bauder H., Wolfgang H.R., Miltner W.H., Taub E., and Weiller C. Treatment-induced cortical reorganization after stroke in humans. Stroke 31 (2000) 1210-1216
140. Boroojerdi B., Diefenbach K., and Ferbert A. Transcallosal inhibition in cortical and subcortical cerebral vascular lesions. J Neurol Sci 144 (1996) 160-170
141. Wittenberg G.F., Chen R., Ishii K., et al. Constraint-induced therapy in stroke: magnetic-stimulation motor maps and cerebral activation. [published erratum in: Neurorehabil Neural Repair 2003;17:197]. Neurorehabil Neural Repair 17 (2003) 48-57
142. Cauraugh J.H., and Kim S. Two coupled motor recovery protocols are better than one: electromyogram-triggered neuromuscular stimulation and bilateral movements. Stroke 33 (2002) 1589-1594
143. Mudie M.H., and Matyas T.A. Can simultaneous bilateral movement involve the undamaged hemisphere in reconstruction of neural networks damaged by stroke?. Disabil Rehabil 22 (2000) 23-37
144. Whitall J., McCombe Waller S., Silver K.H., and Macko R.F. Repetitive bilateral arm training with rhythmic auditory cueing improves motor function in chronic hemiparetic stroke. Stroke 31 (2000) 2390-2395
145. Walter C.B., and Swinnen S.P. Asymmetric interlimb interference during the performance of a dynamic bimanual task. Brain Cogn 14 (1990) 185-200
146. Harris-Love M.L., McCombe Waller S., and Whitall J. Exploiting interlimb coupling to improve paretic arm reaching performance in people with chronic stroke. Arch Phys Med Rehabil 86 (2005) 2131-2137
147. McCombe Waller S., and Whitall J. Central motor excitability with unilateral dominant, unilateral nondominant, and bilateral movement tasks in left and right handed adults [abstract]. J Neurol Phys Ther 28 (2004) 170
148. Celnik P., Stefan K., Hummel F., Duque J., Classen J., and Cohen L.G. Encoding a motor memory in the older adult by action observation. Neuroimage 29 (2005) 677-684
149. Cicinelli P., Marconi B., Zaccagnini M., Pasqualetti P., Filippi M.M., and Rossini P.M. Imagery-induced cortical excitability changes in stroke: a transcranial magnetic stimulation study. Cereb Cortex 16 (2005) 247-253
150. Platz T., van Kaick S., Moller L., Freund S., Winter T., and Kim I.H. Impairment-oriented training and adaptive motor cortex reorganisation after stroke: a fTMS study. J Neurol 252 (2005) 1363-1371