-
1
-
-
0021784714
-
Autoradiographic visualization of beta-adrenoceptor subtypes in human lung
-
Carstairs, J. R., Nimmo, A. J., and Barnes, P. J. (1985), Autoradiographic visualization of beta-adrenoceptor subtypes in human lung. Am. Rev. Respir. Dis. 132, 541-547.
-
(1985)
Am. Rev. Respir. Dis.
, vol.132
, pp. 541-547
-
-
Carstairs, J.R.1
Nimmo, A.J.2
Barnes, P.J.3
-
2
-
-
0029904177
-
Localisation and expression of beta-adrenoceptor subtype mRNAs in human lung
-
Mak, J. C., Nishikawa, M., Haddad, E. B., et al. (1996), Localisation and expression of beta-adrenoceptor subtype mRNAs in human lung. Eur. J. Pharmacol. 302, 215-221.
-
(1996)
Eur. J. Pharmacol.
, vol.302
, pp. 215-221
-
-
Mak, J.C.1
Nishikawa, M.2
Haddad, E.B.3
-
3
-
-
0027317211
-
Long acting inhaled beta-adrenoceptor agonists the comparative pharmacology of formoterol and salmeterol
-
Anderson, G. P. (1993), Long acting inhaled beta-adrenoceptor agonists the comparative pharmacology of formoterol and salmeterol. Agents Actions Suppl. 43, 253-269.
-
(1993)
Agents Actions Suppl.
, vol.43
, pp. 253-269
-
-
Anderson, G.P.1
-
4
-
-
0027156172
-
Formoterol: Pharmacology, molecular basis of agonism, and mechanism of long duration of a highly potent and selective beta 2-adrenoceptor agonist bronchodilator
-
Anderson, G. P. (1993), Formoterol: pharmacology, molecular basis of agonism, and mechanism of long duration of a highly potent and selective beta 2-adrenoceptor agonist bronchodilator. Life Sci. 52, 2145-2160.
-
(1993)
Life Sci.
, vol.52
, pp. 2145-2160
-
-
Anderson, G.P.1
-
5
-
-
0029149511
-
The effects of formoterol on plasma exudation produced by a localized acute inflammatory response to bradykinin in the tracheal mucosa of rats in vivo
-
O'Donnell, S. R. and Anderson, G. P. (1995), The effects of formoterol on plasma exudation produced by a localized acute inflammatory response to bradykinin in the tracheal mucosa of rats in vivo. Br. J. Pharmacol. 116, 1571-1576.
-
(1995)
Br. J. Pharmacol.
, vol.116
, pp. 1571-1576
-
-
O'Donnell, S.R.1
Anderson, G.P.2
-
6
-
-
0030669620
-
Characterization of tolerance to the anti-leakage effect of formoterol in rat airways
-
Bowden, J. J., Anderson, G. P., Lefevre, P. M., Sulakvelidze, I., and McDonald, D. M. (1997), Characterization of tolerance to the anti-leakage effect of formoterol in rat airways. Eur. J. Pharmacol. 338, 83-87.
-
(1997)
Eur. J. Pharmacol.
, vol.338
, pp. 83-87
-
-
Bowden, J.J.1
Anderson, G.P.2
Lefevre, P.M.3
Sulakvelidze, I.4
McDonald, D.M.5
-
7
-
-
0034069055
-
Interactions between corticosteroids and beta-adrenergic agonists in asthma disease induction, progression, and exacerbation
-
Anderson, G. P. (2000), Interactions between corticosteroids and beta-adrenergic agonists in asthma disease induction, progression, and exacerbation. Am. J. Respir. Crit. Care Med. 161, S188-S196.
-
(2000)
Am. J. Respir. Crit. Care Med.
, vol.161
-
-
Anderson, G.P.1
-
8
-
-
0027159827
-
Beta-adrenoceptors on smooth muscle, nerves and inflammatory cells
-
Barnes, P. J. (1993), Beta-adrenoceptors on smooth muscle, nerves and inflammatory cells. Life Sci. 52, 2101-2109.
-
(1993)
Life Sci.
, vol.52
, pp. 2101-2109
-
-
Barnes, P.J.1
-
9
-
-
0027157469
-
The pharmacology of salmeterol
-
Johnson, M., Butchers, P. R., Coleman, R. A., et al. (1993), The pharmacology of salmeterol. Life Sci. 52, 2131-2143.
-
(1993)
Life Sci.
, vol.52
, pp. 2131-2143
-
-
Johnson, M.1
Butchers, P.R.2
Coleman, R.A.3
-
10
-
-
0034105388
-
A long-term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma
-
Kips, J. C., O'Connor, B. J., Inman, M. D., Svensson, K., Pauwels, R. A., and O'Byrne, P. M. (2000), A long-term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma. Am. J. Respir. Crit. Care Med. 161, 996-1001.
-
(2000)
Am. J. Respir. Crit. Care Med.
, vol.161
, pp. 996-1001
-
-
Kips, J.C.1
O'Connor, B.J.2
Inman, M.D.3
Svensson, K.4
Pauwels, R.A.5
O'Byrne, P.M.6
-
11
-
-
27144535903
-
Formoterol attenuates neutrophilic airway inflammation in asthma
-
Maneechotesuwan, K., Essilfie-Quaye, S., Meah, S., et al. (2005), Formoterol attenuates neutrophilic airway inflammation in asthma. Chest 128, 1936-1942.
-
(2005)
Chest
, vol.128
, pp. 1936-1942
-
-
Maneechotesuwan, K.1
Essilfie-Quaye, S.2
Meah, S.3
-
12
-
-
0037180086
-
Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling
-
Roth, M., Johnson, P. R., Rudiger, J. J., et al. (2002), Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. Lancet 360, 1293-1299.
-
(2002)
Lancet
, vol.360
, pp. 1293-1299
-
-
Roth, M.1
Johnson, P.R.2
Rudiger, J.J.3
-
13
-
-
33646452550
-
Combination therapy: Synergistic suppression of virus induced chemokines in airway epithelial cells
-
Edwards, M. R., Johnson, M. W., and Johnston, S. L. (2006), Combination therapy: synergistic suppression of virus induced chemokines in airway epithelial cells. Am. J. Respir. Cell Mol. Biol. 34, 616-624.
-
(2006)
Am. J. Respir. Cell Mol. Biol.
, vol.34
, pp. 616-624
-
-
Edwards, M.R.1
Johnson, M.W.2
Johnston, S.L.3
-
14
-
-
13544253514
-
Safety and tolerability of high-dose formoterol (Aerolizer) and salbutamol (pMDI) in patients with mild/moderate, persistent asthma
-
Kruse, M., Rosenkranz, B., Dobson, C., Ayre, G., and Horowitz, A. (2005), Safety and tolerability of high-dose formoterol (Aerolizer) and salbutamol (pMDI) in patients with mild/moderate, persistent asthma. Pulm. Pharmacol. Ther. 18, 229-234.
-
(2005)
Pulm. Pharmacol. Ther.
, vol.18
, pp. 229-234
-
-
Kruse, M.1
Rosenkranz, B.2
Dobson, C.3
Ayre, G.4
Horowitz, A.5
-
15
-
-
2442442883
-
The pulmonary and extra-pulmonary effects of high-dose formoterol in COPD: A comparison with salbutamol
-
Goldkorn, A., Diotto, P., Burgess, C., et al. (2004), The pulmonary and extra-pulmonary effects of high-dose formoterol in COPD: a comparison with salbutamol. Respirology 9, 102-108.
-
(2004)
Respirology
, vol.9
, pp. 102-108
-
-
Goldkorn, A.1
Diotto, P.2
Burgess, C.3
-
16
-
-
0031924098
-
The extrapulmonary effects of increasing doses of formoterol in patients with asthma
-
Burgess, C., Ayson, M., Rajasingham, S., Crane, J., Della Cioppa, G., and Till, M. D. (1998), The extrapulmonary effects of increasing doses of formoterol in patients with asthma. Eur. J. Clin. Pharmacol. 54, 141-147.
-
(1998)
Eur. J. Clin. Pharmacol.
, vol.54
, pp. 141-147
-
-
Burgess, C.1
Ayson, M.2
Rajasingham, S.3
Crane, J.4
Della Cioppa, G.5
Till, M.D.6
-
17
-
-
0031810916
-
Cardiac effects of formoterol and salmeterol in patients suffering from COPD with preexisting cardiac arrhythmias and hypoxemia
-
Cazzola, M., Imperatore, F., Salzillo, A., et al. (1998), Cardiac effects of formoterol and salmeterol in patients suffering from COPD with preexisting cardiac arrhythmias and hypoxemia. Chest 114, 411-415.
-
(1998)
Chest
, vol.114
, pp. 411-415
-
-
Cazzola, M.1
Imperatore, F.2
Salzillo, A.3
-
18
-
-
29544438051
-
Is there a problem with inhaled long-acting beta-adrenergic agonists?
-
Nelson, H. S. (2006), Is there a problem with inhaled long-acting beta-adrenergic agonists? J. Allergy Clin. Immunol. 117, 3-16.
-
(2006)
J. Allergy Clin. Immunol.
, vol.117
, pp. 3-16
-
-
Nelson, H.S.1
-
19
-
-
29144531153
-
Safety of long-acting beta-agonists - An urgent need to clear the air
-
Martinez, F. D. (2005), Safety of long-acting beta-agonists-an urgent need to clear the air. N. Engl. J. Med. 353, 2637-2639.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 2637-2639
-
-
Martinez, F.D.1
-
20
-
-
0033841788
-
Asthma exacerbations during long term beta agonist use: Influence of beta(2) adrenoceptor polymorphism
-
Taylor, D. R., Drazen, J. M., Herbison, G. P., Yandava, C. N., Hancox, R. J., and Town, G. I. (2000), Asthma exacerbations during long term beta agonist use: influence of beta(2) adrenoceptor polymorphism. Thorax 55, 762-767.
-
(2000)
Thorax
, vol.55
, pp. 762-767
-
-
Taylor, D.R.1
Drazen, J.M.2
Herbison, G.P.3
Yandava, C.N.4
Hancox, R.J.5
Town, G.I.6
-
21
-
-
0033915078
-
The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma
-
Israel, E., Drazen, J. M., Liggett, S. B., et al. (2000), The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma. Am. J. Respir. Crit. Care Med. 162, 75-80.
-
(2000)
Am. J. Respir. Crit. Care Med.
, vol.162
, pp. 75-80
-
-
Israel, E.1
Drazen, J.M.2
Liggett, S.B.3
-
22
-
-
0025760387
-
Prolonged protection against methacholine-induced bronchoconstriction by the inhaled beta 2-agonist formoterol
-
Ramsdale, E. H., Otis, J., Kline, P. A., Gontovnick, L. S., Hargreave, F. E., and O'Byrne, P. M. (1991), Prolonged protection against methacholine-induced bronchoconstriction by the inhaled beta 2-agonist formoterol. Am. Rev. Respir Dis. 143, 998-1001.
-
(1991)
Am. Rev. Respir Dis.
, vol.143
, pp. 998-1001
-
-
Ramsdale, E.H.1
Otis, J.2
Kline, P.A.3
Gontovnick, L.S.4
Hargreave, F.E.5
O'Byrne, P.M.6
-
23
-
-
1842370350
-
Effect of inhaled formoterol and budesonide on exacerbations of asthma
-
Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group
-
Pauwels, R. A., Lofdahl, C. G., Postma, D. S., et al. (1997), Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N. Engl. J. Med. 337, 1405-1411.
-
(1997)
N. Engl. J. Med.
, vol.337
, pp. 1405-1411
-
-
Pauwels, R.A.1
Lofdahl, C.G.2
Postma, D.S.3
-
24
-
-
29444443327
-
Asthma-related exacerbations, therapy switching, and therapy discontinuation: A comparison of 3 commonly used controller regimens
-
O'Connor, R. D., Rosenzweig, J. R., Stanford, R. H., et al. (2005), Asthma-related exacerbations, therapy switching, and therapy discontinuation: a comparison of 3 commonly used controller regimens. Ann. Allergy Asthma Immunol. 95, 535-540.
-
(2005)
Ann. Allergy Asthma Immunol.
, vol.95
, pp. 535-540
-
-
O'Connor, R.D.1
Rosenzweig, J.R.2
Stanford, R.H.3
-
25
-
-
0014439018
-
Salbutamol: A new, selective beta-adrenoceptive receptor stimulant
-
Cullum, V. A., Farmer, J. B., Jack, D., and Levy, G. P. (1969), Salbutamol: a new, selective beta-adrenoceptive receptor stimulant. Br. J. Pharmacol. 35, 141-151.
-
(1969)
Br. J. Pharmacol.
, vol.35
, pp. 141-151
-
-
Cullum, V.A.1
Farmer, J.B.2
Jack, D.3
Levy, G.P.4
-
26
-
-
0025726621
-
The 1990 Lilly Prize Lecture. A way of looking at agonism and antagonism: Lessons from salbutamol, salmeterol and other beta-adrenoceptor agonists
-
Jack, D. (1991), The 1990 Lilly Prize Lecture. A way of looking at agonism and antagonism: lessons from salbutamol, salmeterol and other beta-adrenoceptor agonists. Br. J. Clin. Pharmacol. 31, 501-514.
-
(1991)
Br. J. Clin. Pharmacol.
, vol.31
, pp. 501-514
-
-
Jack, D.1
-
27
-
-
0019497906
-
Anti-allergic activities of the beta-adrenoceptor stimulant formoterol (BD 40A)
-
Tomioka, K., Yamada, T., and Ida, H. (1981), Anti-allergic activities of the beta-adrenoceptor stimulant formoterol (BD 40A). Arch. Int. Pharmacodyn. Ther. 250, 279-292.
-
(1981)
Arch. Int. Pharmacodyn. Ther.
, vol.250
, pp. 279-292
-
-
Tomioka, K.1
Yamada, T.2
Ida, H.3
-
28
-
-
0021059833
-
Anti-allergic activity of formoterol, a new beta-adrenoceptor stimulant, and salbutamol in human leukocytes and human lung tissue
-
Mita, H. and Shida, T. (1983), Anti-allergic activity of formoterol, a new beta-adrenoceptor stimulant, and salbutamol in human leukocytes and human lung tissue. Allergy 38, 547-552.
-
(1983)
Allergy
, vol.38
, pp. 547-552
-
-
Mita, H.1
Shida, T.2
-
29
-
-
0021344063
-
Effects of formoterol (BD 40A), a beta-adrenoceptor stimulant, on isolated guinea-pig lung parenchymal strips and antigen-induced SRS-A release in rats
-
Tomioka, K., Yamada, T., and Tachikawa, S. (1984), Effects of formoterol (BD 40A), a beta-adrenoceptor stimulant, on isolated guinea-pig lung parenchymal strips and antigen-induced SRS-A release in rats. Arch. Int. Pharmacodyn. Ther. 267, 91-102.
-
(1984)
Arch. Int. Pharmacodyn. Ther.
, vol.267
, pp. 91-102
-
-
Tomioka, K.1
Yamada, T.2
Tachikawa, S.3
-
30
-
-
0029841642
-
Sustained activation of a G protein-coupled receptor via "anchored" agonist binding. Molecular localization of the salmeterol exosite within the 2-adrenergic receptor
-
Green, S. A., Spasoff, A. P., Coleman, R. A., Johnson, M., and Liggett, S. B. (1996), Sustained activation of a G protein-coupled receptor via "anchored" agonist binding. Molecular localization of the salmeterol exosite within the 2-adrenergic receptor. J. Biol. Chem. 271, 24,029-24,035.
-
(1996)
J. Biol. Chem.
, vol.271
-
-
Green, S.A.1
Spasoff, A.P.2
Coleman, R.A.3
Johnson, M.4
Liggett, S.B.5
-
31
-
-
0028300203
-
Why are long-acting beta-adrenoceptor agonists long-acting?
-
Anderson, G. P., Linden, A., and Rabe, K. F. (1994), Why are long-acting beta-adrenoceptor agonists long-acting? Eur. Respir. J. 7, 569-578.
-
(1994)
Eur. Respir. J.
, vol.7
, pp. 569-578
-
-
Anderson, G.P.1
Linden, A.2
Rabe, K.F.3
-
32
-
-
0033940928
-
Systemic effects of formoterol and salmeterol: A dose-response comparison in healthy subjects
-
Guhan, A. R., Cooper, S., Oborne, J., Lewis, S., Bennett, J., and Tattersfield, A. E. (2000), Systemic effects of formoterol and salmeterol: a dose-response comparison in healthy subjects. Thorax 55, 650-656.
-
(2000)
Thorax
, vol.55
, pp. 650-656
-
-
Guhan, A.R.1
Cooper, S.2
Oborne, J.3
Lewis, S.4
Bennett, J.5
Tattersfield, A.E.6
-
33
-
-
0030849878
-
Several studies have shown salmeterol to be more potent than salbutamol for systemic effects
-
Bennett, J. and Tattersfield, A. E. (1997), Several studies have shown salmeterol to be more potent than salbutamol for systemic effects. B.M.J. 315, 121.
-
(1997)
B.M.J.
, vol.315
, pp. 121
-
-
Bennett, J.1
Tattersfield, A.E.2
-
34
-
-
0020597547
-
Dose-response curves to inhaled beta-adrenoceptor agonists in normal and asthmatic subjects
-
Barnes, P. J. and Pride, N. B. (1983), Dose-response curves to inhaled beta-adrenoceptor agonists in normal and asthmatic subjects. Br. J. Clin. Pharmacol. 15, 677-682.
-
(1983)
Br. J. Clin. Pharmacol.
, vol.15
, pp. 677-682
-
-
Barnes, P.J.1
Pride, N.B.2
-
35
-
-
0031926358
-
Long- and short-acting beta2 adrenoceptor agonists: Interactions in human contracted bronchi
-
Molimard, M., Naline, E., Zhang, Y., Le Gros, V., Begaud, B., and Advenier, C. (1998), Long- and short-acting beta2 adrenoceptor agonists: interactions in human contracted bronchi. Eur. Respir. J. 11, 583-588.
-
(1998)
Eur. Respir. J.
, vol.11
, pp. 583-588
-
-
Molimard, M.1
Naline, E.2
Zhang, Y.3
Le Gros, V.4
Begaud, B.5
Advenier, C.6
-
36
-
-
0032992412
-
Differential effect of formoterol on adenosine monophosphate and histamine reactivity in asthma
-
Nightingale, J. A., Rogers, D. F., and Barnes, P. J. (1999), Differential effect of formoterol on adenosine monophosphate and histamine reactivity in asthma. Am. J. Respir. Crit. Care Med. 159, 1786-1790.
-
(1999)
Am. J. Respir. Crit. Care Med.
, vol.159
, pp. 1786-1790
-
-
Nightingale, J.A.1
Rogers, D.F.2
Barnes, P.J.3
-
37
-
-
1542267836
-
Predicted 3D structure for the human beta 2 adrenergic receptor and its binding site for agonists and antagonists
-
Freddolino, P. L., Kalani, M. Y., Vaidehi, N., et al. (2004), Predicted 3D structure for the human beta 2 adrenergic receptor and its binding site for agonists and antagonists. Proc. Natl. Acad. Sci. USA 101, 2736-2741.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2736-2741
-
-
Freddolino, P.L.1
Kalani, M.Y.2
Vaidehi, N.3
-
38
-
-
0023173659
-
Ligand binding to the beta-adrenergic receptor involves its rhodopsin-like core
-
Dixon, R. A., Sigal, I. S., Rands, E., et al. (1987), Ligand binding to the beta-adrenergic receptor involves its rhodopsin-like core. Nature 326, 73-77.
-
(1987)
Nature
, vol.326
, pp. 73-77
-
-
Dixon, R.A.1
Sigal, I.S.2
Rands, E.3
-
39
-
-
0025303260
-
Mutational analysis of beta-adrenergic receptor glycosylation
-
Rands, E., Candelore, M. R., Cheung, A. H., Hill, W. S., Strader, C. D., and Dixon, R. A. (1990), Mutational analysis of beta-adrenergic receptor glycosylation. J. Biol. Chem. 265, 10,759-10,764.
-
(1990)
J. Biol. Chem.
, vol.265
-
-
Rands, E.1
Candelore, M.R.2
Cheung, A.H.3
Hill, W.S.4
Strader, C.D.5
Dixon, R.A.6
-
40
-
-
0024544232
-
Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor
-
O'Dowd, B. F., Hnatowich, M., Caron, M. G., Lefkowitz, R. J., and Bouvier, M. (1989), Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor. J. Biol. Chem. 264, 7564-7569.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 7564-7569
-
-
O'Dowd, B.F.1
Hnatowich, M.2
Caron, M.G.3
Lefkowitz, R.J.4
Bouvier, M.5
-
41
-
-
0029811834
-
Palmitoylated cysteine 341 modulates phosphorylation of the beta2-adrenergic receptor by the cAMP-dependent protein kinase
-
Moffett, S., Adam, L., Bonin, H., Loisel, T. P., Bouvier, M., and Mouillac, B. (1996), Palmitoylated cysteine 341 modulates phosphorylation of the beta2-adrenergic receptor by the cAMP-dependent protein kinase. J. Biol. Chem. 271, 21,490-21,497.
-
(1996)
J. Biol. Chem.
, vol.271
-
-
Moffett, S.1
Adam, L.2
Bonin, H.3
Loisel, T.P.4
Bouvier, M.5
Mouillac, B.6
-
42
-
-
0035163581
-
The palmitoylation state of the beta(2)-adrenergic receptor regulates the synergistic action of cyclic AMP-dependent protein kinase and beta-adrenergic receptor kinase involved in its phosphorylation and desensitization
-
Moffett, S., Rousseau, G., Lagace, M., and Bouvier, M. (2001), The palmitoylation state of the beta(2)-adrenergic receptor regulates the synergistic action of cyclic AMP-dependent protein kinase and beta-adrenergic receptor kinase involved in its phosphorylation and desensitization. J. Neurochem. 76, 269-279.
-
(2001)
J. Neurochem.
, vol.76
, pp. 269-279
-
-
Moffett, S.1
Rousseau, G.2
Lagace, M.3
Bouvier, M.4
-
43
-
-
0023263617
-
Identification of residues required for ligand binding to the beta-adrenergic receptor
-
Strader, C. D., Sigal, I. S., Register, R. B., Candelore, M. R., Rands, E., and Dixon, R. A. (1987), Identification of residues required for ligand binding to the beta-adrenergic receptor. Proc. Natl. Acad. Sci. USA 84, 4384-4388.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 4384-4388
-
-
Strader, C.D.1
Sigal, I.S.2
Register, R.B.3
Candelore, M.R.4
Rands, E.5
Dixon, R.A.6
-
44
-
-
0023447821
-
Structural features required for ligand binding to the beta-adrenergic receptor
-
Dixon, R. A., Sigal, I. S., Candelore, M. R., et al. (1987), Structural features required for ligand binding to the beta-adrenergic receptor. Embo. J. 6, 3269-3275.
-
(1987)
Embo. J.
, vol.6
, pp. 3269-3275
-
-
Dixon, R.A.1
Sigal, I.S.2
Candelore, M.R.3
-
45
-
-
0642345203
-
Apoptosis in the normal and inflamed airway epithelium: Role of zinc in epithelial protection and procaspase-3 regulation
-
Truong-Tran, A. Q., Grosser, D., Ruffin, R. E., Murgia, C., and Zalewski, P. D. (2003), Apoptosis in the normal and inflamed airway epithelium: role of zinc in epithelial protection and procaspase-3 regulation. Biochem. Pharmacol. 66, 1459-1468.
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 1459-1468
-
-
Truong-Tran, A.Q.1
Grosser, D.2
Ruffin, R.E.3
Murgia, C.4
Zalewski, P.D.5
-
46
-
-
0037414774
-
Identification of an allosteric binding site for Zn2+ on the beta2 adrenergic receptor
-
Swaminath, G., Lee, T. W., and Kobilka, B. (2003), Identification of an allosteric binding site for Zn2+ on the beta2 adrenergic receptor. J. Biol. Chem. 278, 352-356.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 352-356
-
-
Swaminath, G.1
Lee, T.W.2
Kobilka, B.3
-
47
-
-
0035876397
-
The Ile164 beta(2)-adrenoceptor polymorphism alters salmeterol exosite binding and conventional agonist coupling to G(s)
-
Green, S. A., Rathz, D. A., Schuster, A. J., and Liggett, S. B. (2001), The Ile164 beta(2)-adrenoceptor polymorphism alters salmeterol exosite binding and conventional agonist coupling to G(s). Eur. J. Pharmacol. 421, 141-147.
-
(2001)
Eur. J. Pharmacol.
, vol.421
, pp. 141-147
-
-
Green, S.A.1
Rathz, D.A.2
Schuster, A.J.3
Liggett, S.B.4
-
48
-
-
4043125390
-
Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting
-
Salahpour, A., Angers, S., Mercier, J. F., Lagace, M., Marullo, S., and Bouvier, M. (2004), Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. J. Biol. Chem. 279, 33,390-33,397.
-
(2004)
J. Biol. Chem.
, vol.279
-
-
Salahpour, A.1
Angers, S.2
Mercier, J.F.3
Lagace, M.4
Marullo, S.5
Bouvier, M.6
-
49
-
-
0032519493
-
Functional rescue of a constitutively desensitized beta2AR through receptor dimerization
-
Hebert, T. E., Loisel, T. P., Adam, L., Ethier, N., Onge, S. S., and Bouvier, M. (1998), Functional rescue of a constitutively desensitized beta2AR through receptor dimerization. Biochem. J. 330 (Pt 1), 287-293.
-
(1998)
Biochem. J.
, vol.330
, Issue.PART 1
, pp. 287-293
-
-
Hebert, T.E.1
Loisel, T.P.2
Adam, L.3
Ethier, N.4
Onge, S.S.5
Bouvier, M.6
-
50
-
-
23344449115
-
Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility
-
Zhu, W. Z., Chakir, K., Zhang, S., et al. (2005), Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility. Circ. Res. 97, 244-251.
-
(2005)
Circ. Res.
, vol.97
, pp. 244-251
-
-
Zhu, W.Z.1
Chakir, K.2
Zhang, S.3
-
51
-
-
3142617997
-
Heterooligomerization between beta2- and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties
-
Breit, A., Lagace, M., and Bouvier, M. (2004), Heterooligomerization between beta2- and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties. J. Biol. Chem. 279, 28,756-28,765.
-
(2004)
J. Biol. Chem.
, vol.279
-
-
Breit, A.1
Lagace, M.2
Bouvier, M.3
-
52
-
-
0037160105
-
Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer
-
Mercier, J. F., Salahpour, A., Angers, S., Breit, A., and Bouvier, M. (2002), Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer. J. Biol. Chem. 277, 44,925-44,931.
-
(2002)
J. Biol. Chem.
, vol.277
-
-
Mercier, J.F.1
Salahpour, A.2
Angers, S.3
Breit, A.4
Bouvier, M.5
-
53
-
-
0037144542
-
Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy
-
Lavoie, C., Mercier, J. F., Salahpour, A., et al. (2002), Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy. J. Biol. Chem. 277, 35,402-35,410.
-
(2002)
J. Biol. Chem.
, vol.277
-
-
Lavoie, C.1
Mercier, J.F.2
Salahpour, A.3
-
54
-
-
0037224730
-
Biochemical characterization of beta2-adrenergic receptor dimers and oligomers
-
Salahpour, A., Bonin, H., Bhalla, S., Petaja-Repo, U., and Bouvier, M. (2003), Biochemical characterization of beta2-adrenergic receptor dimers and oligomers. Biol. Chem. 384, 117-123.
-
(2003)
Biol. Chem.
, vol.384
, pp. 117-123
-
-
Salahpour, A.1
Bonin, H.2
Bhalla, S.3
Petaja-Repo, U.4
Bouvier, M.5
-
55
-
-
0034858918
-
Evidence that the anti-spasmogenic effect of the betaadrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase
-
Spicuzza, L., Belvisi, M. G., Birrell, M. A., Barnes, P. J., Hele, D. J., and Giembycz, M. A. (2001), Evidence that the anti-spasmogenic effect of the betaadrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase. Br. J. Pharmacol. 133, 1201-1212.
-
(2001)
Br. J. Pharmacol.
, vol.133
, pp. 1201-1212
-
-
Spicuzza, L.1
Belvisi, M.G.2
Birrell, M.A.3
Barnes, P.J.4
Hele, D.J.5
Giembycz, M.A.6
-
56
-
-
0032555156
-
A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins
-
Hall, R. A., Ostedgaard, L. S., Premont, R. T., et al. (1998), A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins. Proc. Natl. Acad. Sci. USA 95, 8496-8501.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8496-8501
-
-
Hall, R.A.1
Ostedgaard, L.S.2
Premont, R.T.3
-
57
-
-
0032498963
-
The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
-
Hall, R. A., Premont, R. T., Chow, C. W., et al. (1998), The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. Nature 392, 626-630.
-
(1998)
Nature
, vol.392
, pp. 626-630
-
-
Hall, R.A.1
Premont, R.T.2
Chow, C.W.3
-
58
-
-
0027272989
-
Beta-adrenoceptor subtypes and the opening of plasmalemmal K(+)-channels in trachealis muscle: Electrophysiological and mechanical studies in guinea-pig tissue
-
Cook, S. J., Small, R. C., Berry, J. L., Chiu, P., Downing, S. J., and Foster, R. W. (1993), Beta-adrenoceptor subtypes and the opening of plasmalemmal K(+)-channels in trachealis muscle: electrophysiological and mechanical studies in guinea-pig tissue. Br. J. Pharmacol. 109, 1140-1148.
-
(1993)
Br. J. Pharmacol.
, vol.109
, pp. 1140-1148
-
-
Cook, S.J.1
Small, R.C.2
Berry, J.L.3
Chiu, P.4
Downing, S.J.5
Foster, R.W.6
-
59
-
-
0035834428
-
Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin
-
Shenoy, S. K., McDonald, P. H., Kohout, T. A., and Lefkowitz, R. J. (2001), Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science 294, 1307-1313.
-
(2001)
Science
, vol.294
, pp. 1307-1313
-
-
Shenoy, S.K.1
McDonald, P.H.2
Kohout, T.A.3
Lefkowitz, R.J.4
-
60
-
-
0037195909
-
G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase
-
Lavine, N., Ethier, N., Oak, J. N., et al. (2002), G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase. J. Biol. Chem. 277, 46,010-46,019.
-
(2002)
J. Biol. Chem.
, vol.277
-
-
Lavine, N.1
Ethier, N.2
Oak, J.N.3
-
61
-
-
32244438409
-
Differential phosphorylation and dephosphorylation of beta(2)-adrenoceptor sites Ser262 and Ser355,356
-
Iyer, V., Tran, T. M., Foster, E., Dai, W., Clark, R. B., and Knoll, B. J. (2006), Differential phosphorylation and dephosphorylation of beta(2)-adrenoceptor sites Ser262 and Ser355,356. Br. J. Pharmacol. 147, 249-259.
-
(2006)
Br. J. Pharmacol.
, vol.147
, pp. 249-259
-
-
Iyer, V.1
Tran, T.M.2
Foster, E.3
Dai, W.4
Clark, R.B.5
Knoll, B.J.6
-
62
-
-
0033013813
-
Sustained bronchoprotection, bronchodilatation, and symptom control during regular formoterol use in asthma of moderate or greater severity
-
The Canadian FO/OD1 Study Group
-
FitzGerald, J. M., Chapman, K. R., Della Cioppa, G., et al. (1999), Sustained bronchoprotection, bronchodilatation, and symptom control during regular formoterol use in asthma of moderate or greater severity. The Canadian FO/OD1 Study Group. J. Allergy Clin. Immunol. 103, 427-435.
-
(1999)
J. Allergy Clin. Immunol.
, vol.103
, pp. 427-435
-
-
FitzGerald, J.M.1
Chapman, K.R.2
Della Cioppa, G.3
-
63
-
-
0031663235
-
Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol
-
Aziz, I., Tan, K. S., Hall, I. P., Devlin, M. M., and Lipworth, B. J. (1998), Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol. Eur. Respir. J. 12, 580-584.
-
(1998)
Eur. Respir. J.
, vol.12
, pp. 580-584
-
-
Aziz, I.1
Tan, K.S.2
Hall, I.P.3
Devlin, M.M.4
Lipworth, B.J.5
-
64
-
-
0347319054
-
The arginine-16 beta2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol
-
Lee, D. K., Currie, G. P., Hall, I. P., Lima, J. J., and Lipworth, B. J. (2004), The arginine-16 beta2-adrenoceptor polymorphism predisposes to bronchoprotective subsensitivity in patients treated with formoterol and salmeterol. Br. J. Clin. Pharmacol. 57, 68-75.
-
(2004)
Br. J. Clin. Pharmacol.
, vol.57
, pp. 68-75
-
-
Lee, D.K.1
Currie, G.P.2
Hall, I.P.3
Lima, J.J.4
Lipworth, B.J.5
-
65
-
-
0002736850
-
Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients
-
Tan, K. S., Grove, A., McLean, A., Gnosspelius, Y., Hall, I. P., and Lipworth, B. J. (1997), Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients. Am. J. Respir. Crit. Care Med. 156, 28-35.
-
(1997)
Am. J. Respir. Crit. Care Med.
, vol.156
, pp. 28-35
-
-
Tan, K.S.1
Grove, A.2
McLean, A.3
Gnosspelius, Y.4
Hall, I.P.5
Lipworth, B.J.6
-
66
-
-
0033954649
-
Bronchodilator response to albuterol after regular formoterol and effects of acute corticosteroid administration
-
Lipworth, B. J. and Aziz, I. (2000), Bronchodilator response to albuterol after regular formoterol and effects of acute corticosteroid administration. Chest 117, 156-162.
-
(2000)
Chest
, vol.117
, pp. 156-162
-
-
Lipworth, B.J.1
Aziz, I.2
-
67
-
-
0031866450
-
Tolerance to the protective effects of salmeterol on methacholine-induced bronchoconstriction: Influence of inhaled corticosteroids
-
Boulet, L. P., Cartier, A., Milot, J., Cote, J., Malo, J. L., and Laviolette, M. (1998), Tolerance to the protective effects of salmeterol on methacholine-induced bronchoconstriction: influence of inhaled corticosteroids. Eur. Respir. J. 11, 1091-1097.
-
(1998)
Eur. Respir. J.
, vol.11
, pp. 1091-1097
-
-
Boulet, L.P.1
Cartier, A.2
Milot, J.3
Cote, J.4
Malo, J.L.5
Laviolette, M.6
-
68
-
-
0030604281
-
Effect of short- and long-acting beta 2-adrenoceptor agonists on pulmonary beta 2-adrenoceptor expression in human lung
-
Nishikawa, M., Mak, J. C., and Barnes, P. J. (1996), Effect of short- and long-acting beta 2-adrenoceptor agonists on pulmonary beta 2-adrenoceptor expression in human lung. Eur. J. Pharmacol. 318, 123-129.
-
(1996)
Eur. J. Pharmacol.
, vol.318
, pp. 123-129
-
-
Nishikawa, M.1
Mak, J.C.2
Barnes, P.J.3
-
69
-
-
0026522971
-
Formoterol, fenoterol, and salbutamol as partial agonists for relaxation of maximally contracted guinea pig tracheae: Comparison of relaxation with receptor binding
-
Lemoine, H., Overlack, C., Kohl, A., Worth, H., and Reinhardt, D. (1992), Formoterol, fenoterol, and salbutamol as partial agonists for relaxation of maximally contracted guinea pig tracheae: comparison of relaxation with receptor binding. Lung 170, 163-180.
-
(1992)
Lung
, vol.170
, pp. 163-180
-
-
Lemoine, H.1
Overlack, C.2
Kohl, A.3
Worth, H.4
Reinhardt, D.5
-
70
-
-
0026638371
-
Highly potent beta-2 sympathomimetics convert to less potent partial agonists as relaxants of guinea pig tracheae maximally contracted by carbachol. Comparison of relaxation with receptor binding and adenylate cyclase stimulation
-
Lemoine, H. and Overlack, C. (1992), Highly potent beta-2 sympathomimetics convert to less potent partial agonists as relaxants of guinea pig tracheae maximally contracted by carbachol. Comparison of relaxation with receptor binding and adenylate cyclase stimulation. J. Pharmacol. Exp. Ther. 261, 258-270.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.261
, pp. 258-270
-
-
Lemoine, H.1
Overlack, C.2
-
71
-
-
0025959676
-
Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration
-
Campbell, P. T., Hnatowich, M., O'Dowd, B. F., Caron, M. G., Lefkowitz, R. J., and Hausdorff, W. P. (1991), Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration. Mol. Pharmacol. 39, 192-198.
-
(1991)
Mol. Pharmacol.
, vol.39
, pp. 192-198
-
-
Campbell, P.T.1
Hnatowich, M.2
O'Dowd, B.F.3
Caron, M.G.4
Lefkowitz, R.J.5
Hausdorff, W.P.6
-
72
-
-
0032879689
-
Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis
-
Jockers, R., Angers, S., Da Silva, A., et al. (1999), Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis. J. Biol. Chem. 274, 28,900-28,908.
-
(1999)
J. Biol. Chem.
, vol.274
-
-
Jockers, R.1
Angers, S.2
Da Silva, A.3
-
73
-
-
0033917738
-
Albuterol-induced downregulation of Gsalpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo
-
Finney, P. A., Belvisi, M. G., Donnelly, L. E., et al. (2000), Albuterol-induced downregulation of Gsalpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo. J. Clin. Invest. 106, 125-135.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 125-135
-
-
Finney, P.A.1
Belvisi, M.G.2
Donnelly, L.E.3
-
74
-
-
0025183653
-
Role of phosphoinositide metabolism in human bronchial smooth muscle contraction and in functional antagonism by beta-adrenoceptor agonists
-
Van Amsterdam, R. G., Meurs, H., Ten Berge, R. E., Veninga, N. C., Brouwer, F., and Zaagsma, J. (1990), Role of phosphoinositide metabolism in human bronchial smooth muscle contraction and in functional antagonism by beta-adrenoceptor agonists. Am. Rev. Respir. Dis. 142, 1124-1128.
-
(1990)
Am. Rev. Respir. Dis.
, vol.142
, pp. 1124-1128
-
-
Van Amsterdam, R.G.1
Meurs, H.2
Ten Berge, R.E.3
Veninga, N.C.4
Brouwer, F.5
Zaagsma, J.6
-
75
-
-
0027551037
-
Organ culture with proinflammatory cytokines reproduces impairment of the beta-adrenoceptor-mediated relaxation in tracheas of a guinea pig antigen model
-
Wills-Karp, M., Uchida, Y., Lee, J. Y., Jinot, J., Hirata, A., and Hirata, F. (1993), Organ culture with proinflammatory cytokines reproduces impairment of the beta-adrenoceptor-mediated relaxation in tracheas of a guinea pig antigen model. Am. J. Respir. Cell Mol. Biol. 8, 153-159.
-
(1993)
Am. J. Respir. Cell Mol. Biol.
, vol.8
, pp. 153-159
-
-
Wills-Karp, M.1
Uchida, Y.2
Lee, J.Y.3
Jinot, J.4
Hirata, A.5
Hirata, F.6
-
76
-
-
0026874022
-
A comparison of beta-adrenergic receptors and in vitro relaxant responses to isoproterenol in asthmatic airway smooth muscle
-
Bai, T. R., Mak, J. C., and Barnes, P. J. (1992), A comparison of beta-adrenergic receptors and in vitro relaxant responses to isoproterenol in asthmatic airway smooth muscle. Am. J. Respir. Cell Mol. Biol. 6, 647-651.
-
(1992)
Am. J. Respir. Cell Mol. Biol.
, vol.6
, pp. 647-651
-
-
Bai, T.R.1
Mak, J.C.2
Barnes, P.J.3
-
77
-
-
0025977594
-
Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus
-
Bai, T. R. (1991), Abnormalities in airway smooth muscle in fatal asthma. A comparison between trachea and bronchus. Am. Rev. Respir. Dis. 143, 441-443.
-
(1991)
Am. Rev. Respir. Dis.
, vol.143
, pp. 441-443
-
-
Bai, T.R.1
-
78
-
-
85047694597
-
Antithetic regulation by beta-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway beta-agonist paradox
-
McGraw, D. W., Almoosa, K. F., Paul, R. J., Kobilka, B. K., and Liggett, S. B. (2003), Antithetic regulation by beta-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway beta-agonist paradox. J. Clin. Invest. 112, 619-626.
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 619-626
-
-
McGraw, D.W.1
Almoosa, K.F.2
Paul, R.J.3
Kobilka, B.K.4
Liggett, S.B.5
-
79
-
-
1842737696
-
Effects of acute and chronic administration of beta-adrenoceptor ligands on airway function in a murine model of asthma
-
Callaerts-Vegh, Z., Evans, K. L., Dudekula, N., et al. (2004), Effects of acute and chronic administration of beta-adrenoceptor ligands on airway function in a murine model of asthma. Proc. Natl. Acad. Sci. USA 101, 4948-4953.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4948-4953
-
-
Callaerts-Vegh, Z.1
Evans, K.L.2
Dudekula, N.3
|