Recovery from bronchoconstriction and bronchodilator tolerance

Clinical Reviews in Allergy and Immunology

Volumn 31, Issue 2-3, 2006, Pages 181-196

  Haney, Sarah ^a   Hancox, Robert J ^a,b  

^a WAIKATO HOSPITAL   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

agonist; Bronchodilator; Tachyphylaxis; Tolerance

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; FORMOTEROL; MANNITOL; METHACHOLINE; SALBUTAMOL; SODIUM CHLORIDE; STEROID; TERBUTALINE;

ASTHMA; BRONCHODILATATION; CLINICAL TRIAL; DRUG EFFECT; DRUG TOLERABILITY; FORCED EXPIRATORY VOLUME; HUMAN; MORBIDITY; MORTALITY; REVIEW; TACHYCARDIA; TACHYPHYLAXIS; TREMOR;

BRONCHOCONSTRICTION; BRONCHODILATOR AGENTS; DRUG TOLERANCE; HUMANS; RECOVERY OF FUNCTION;

EID: 33751325028     PISSN: 10800549     EISSN: None     Source Type: Journal    
DOI: 10.1385/CRIAI:31:2:181     Document Type: Review

References (64)

1. Jenne, J. W. (1982), Whither beta-adrenergic tachyphylaxis? J. Allergy Clin. Immunol. 70, 413-416.
2. Nelson, H. S., Raine, D. Jr, Doner, H. C., and Posey, W. C. (1977), Subsensitivity to the bronchodilator action of albuterol produced by chronic administration. Am. Rev. Respir. Dis. 116, 871-878.
3. Harvey, J. E. and Tattersfield, A. E. (1982), Airway response to salbutamol: effect of regular salbutamol inhalations in normal, atopic and asthmatic subjects. Thorax 37, 280-287.
4. Lipworth, B. J., Struthers, A. D., and McDevitt, D. G. (1999), Tachphylaxis to systemic but not to airway responses during prolonged therapy with high dose inhaled salbutamol in asthmatics. Am. Rev. Respir. Dis. 140, 586-592.
5. Weber, R. W., Smith, J. A., and Nelson, H. S. (1982), Aerosolized terbutaline in asthmatics: development of subsensitivity with long-term administration. J. Allergy Clin. Immunol. 70, 417-422.
6. 2-agonist therapy: Vox clamatis in deserto vel lux in tenebris. J. Allergy Clin. Immunol. 95, 641-651.
7. 2-agonist therapy: a safety review of long-acting agents. Intern. J. Clin. Practice 57, 689-697.
8. 2-agonists on airway tone and bronchial responsiveness. J. Allergy Clin. Immunol. 110, S304-S312.
9. Barnes, P. J. (1995), Beta-adrenergic receptors and their regulation. Am. J. Respir. Crit. Care Med. 152, 838-860.
10. 2-adrenocepter polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics. Am. J. Respir. Crit. Care Med. 156, 28-35.
11. 2 adrenergic responses after regular twice daily treatment with eformeterol dry powder in asthmatic patients. Thorax 50, 497-504.
12. Lipworth, B. J., Clark, R. A., Dhillon, D. P., and McDevitt, D. G. (1990), Subsensitivity of beta-adrenoceptor responses in asthmatic patients taking regular low dose inhaled salbutamol. Eur. J. Clin. Pharmacol. 38, 203-205.
13. 2 agonists. Thorax 51, 1051-1056.
14. O'Connor, B. J., Aikman, S. L., and Barnes, P. J. (1992), Tolerance to the nonbronchodilator effects of inhaled beta-agonists in asthma. N. Engl. J. Med. 327, 1204-1208.
15. 2-adrenocepter agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma. N. Engl. J. Med. 327, 1198-1203.
16. Yates, D. H., Sussman, H. S., Shaw, M. J., Barnes, P. J., and Chung, K. F. (1995), Regular formoterol treatment in mild asthma. Effect on bronchial responsiveness during and after treatment. Am. J. Respir. Crit. Care Med. 152, 1170-1174.
17. Inman, M. D. and O'Byrne, P. M. (1996), The effect of regular inhaled albuterol on exercise-induced bronchoconstriction. Am. J. Respir. Crit. Care Med. 153, 65-69.
18. Cockcroft, D. W., McParland, C. M., Britto, S. A., Swystun, V. A., and Rutherford, B. C. (1993), Regular inhaled salbutamol and airway responsiveness to allergen. Lancet 342, 833-837.
19. Johnson, M. (1998), The β-adrenoceptor. Am. J. Respir. Crit. Care Med. 158, S146-S153.
20. Storms, W. W., Chervinsky, P., Ghannam, A., Bird, S., Hustad, C. M., and Edelman, J. M. (2004), A comparison of the effects of oral montelukast and inhaled salmeterol on response to resuce bronchodilation after challenge. Respir. Med. 98, 1051-1062.
21. 2- agonists in individuals with asthma. Am. J. Respir. Crit. Care Med. 163, 474-477.
22. Hendeles, L., Beaty, R., Ahrens, R., Stevens, G., and Harman, E. M. (2004), Response to inhaled albuterol during nocturnal asthma. J. Allergy Clin. Immunol. 113, 1058-1062.
23. Hancox, R. J., Aldridge, R. E., Cowan, J. O., et al. (1999), Tolerance to beta agonists during acute bronchoconstriction. Eur. Respir. J. 14, 283-287.
24. Hancox, R. J., Cowan, J. O., Flannery, E. M., Herbison, G. P., McLachlan, C. R., and Taylor, D. R. (2000), Bronchodilator tolerance and rebound bronchoconstriction during regular inhaled beta-agonist treatment. Respir. Med. 94, 767-771.
25. Jones, S. L., Cowan, J. O., Flannery, E. M., Hancox, R. J., Herbison, G. P., and Taylor, D. R. (2001), Reversing acute bronchoconstriction in asthma: the effect of bronchodilator tolerance. Eur. Respir. J. 17, 368-373.
26. Wraight, J. M., Hancox, R. J., Herbison, G. P., Cowan, J. O., Flannery, E. M., and Taylor, D. R. (2003), Bronchodilator tolerance: the impact of increasing bronchoconstriction. Eur. Respir. J. 21, 810-815.
27. 2 adrenoceptor genotype-16 in asthmatic patients receiving regular formoterol or salmeterol. Thorax 59, 662-667.
28. 2 agonists. Thorax 56, 529-535.
29. Haney, S. and Hancox, R. J. (2005), Tolerance to bronchodilation during treatment with long-acting beta-agonists, a randomised controlled trial. Respir. Res. 6, 107.
30. Haney, S. and Hancox, R. J. (2005), Rapid onset of tolerance to beta-agonist bronchodilation. Respir. Med. 99, 566-571.
31. Taylor, D. R., Town, G. I., Herbison, G. P., et al. (1998), Asthma control during long-term treatment with regular inhaled salbutamol and salmeterol. Thorax 53, 744-752.
32. 2 agonist, inhaled corticosteroid and their combination in the treatment of asthma. Thorax 54, 482-487.
33. Lee, D. K. C., Jackson, C. M., Currie, G. P., Cockburn, W. J., and Lipworth, B.J. (2003), Comparison of combination inhalers vs inhaled corticosteroids alone in moderate persistent asthma. Br. J. Clin. Pharmacol. 56, 494-500.
34. British Thoracic Society, Scottish Intercollegiate Guidelines Network (2003), British guideline on the management of asthma. Thorax 58, 1-83.
35. Dollery, C. ed (1999), Therapeutic Drugs. Churchill Livingstone, pp. F155-F158.
36. 2-agonist. Am. J. Respir. Crit. Care Med. 154, 1603-1607.
37. Masoli, M., Holt, S., Weatherall, M., and Beasley, R. (2004), Dose-response relationship of inhaled budesonide in adult asthma: a meta-analysis. Eur. Respir. J. 24, 552-558.
38. Lipworth, B. J. and Aziz, I. (2000), Bronchodilator response to albuterol after regular formoterol and effects of acute corticosteroid administration. Chest 117, 156-162.
39. American Thoracic Society. (2000), Guidelines for methacholine and exercise challenge testing - 1999. Am. J. Respir. Crit. Care Med. 161, 309-329.
40. 2 agonist tolerance and exercise-induced bronchospasm. Am. J. Respir. Crit. Care Med. 165, 1068-1070.
41. Haney, S. and Hancox, R. J. (2005), The bronchodilator response to ipratropium is not affected by regular β-agonist use [abstract]. Eur. Respir. J. 26, 123S.
42. Makker, H. K. and Holgate, S. T. (1993), Relation of the hypertonic saline responsiveness of the airways to exercise induced asthma symptom severity and to histamine or methacholine reactivity. Thorax 48, 142-147.
43. Sterk, P. J., Fabbri, L. M., Quanjer, P. H., et al. (1993), Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Eur. Respir. J. 6, 53-83.
44. Brannan, J., Freed-Martens, R., and Anderson, S. D. (2005), Effect of treatment on recovery to mannitol challenge: a phase 3 study [abstract]. Eur. Respir J. 26, 371S.
45. Rodrigo, C. and Rodrigo, G. (1998), Therapeutic response patterns to high and cumulative doses of salbutamol in acute severe asthma. Chest 113, 593-598.
46. Korosec, M., Novak, R. D., Myers, E., Skowronski, M., and McFadden, E. R. (1999), Salmeterol does not compromise the bronchodilator response to albuterol during acute episodes of asthma. Am. J. Med. 107, 209-213.
47. Windom, H. H., Burgess, C. D., Crane, J., Pearce, N., Kwong, T., and Beasley, R. (1990), The self-administration of inhaled beta agonist drugs during severe asthma. N. Zealand Med. J. 103, 205-207.
48. Haney, S. and Hancox, R. J. (2005), Tolerance to bronchodilation is not overcome by high dose salbutamol [abstract]. Eur. Respir. J. 26, 122S,123S.
49. 2-adrenoceptor agonists in asthma management. Respir. Med. 99, 152-170.
50. Zuo, Z. (2005), The role of opioid receptor internalization and beta-arrestins in the development of opioid tolerance. Anesth. Analg. 101, 728-734.
51. Kosmicki, M., Sadowski, Z., Szwed, H., and Kowalik, I. (2000), What intervals in oral therapy of isosirbide dinitrate in various doses are sufficient to prevent dinitrate tolerance? Med. Sci. Mon. 6, 763-768.
52. Davis, B. E., Reid, J. K., and Cockcroft, D. W. (2003), Formoterol thrice weekly does not result in the development of tolerance to bronchoprotection. Can. Respir. J. 10, 23-26.
53. Brodde, O. E., Daul, A., Michel-Reher, M., et al. (1990), Agonist-induced desensitization of β-adrenoceptor function in humans. Circulation 81, 914-921.
54. van den Berg, W., Leferink, J. G., Fokkens, J. K., Kreukniet, J., Maes, R. A. A., and Bruynzeel, P. L. B. (1982), Clinical implications of drug-induced desensitization of the beta receptor after continuous oral terbutaline. J. Allergy Clin. Immunol. 69, 410-417.
55. Bhagat, R., Kalra, S., Swystun, V. A., and Cockcroft, D. W. (1995), Rapid onset of tolerance to the bronchoprotective effect of salmeterol. Chest 108, 1235-1239.
56. 2-agonists. Pulmon. Pharmacol. Therapeut. 16, 153-161.
57. Smith, A. P., Orehek, J., and Charpin, J. (1977), Bronchodilator drug tests in normal subjects. Br. J. Dis. Chest 71, 234-236.
58. Houghton, C. M., Woodcock, A. A., and Singh, D. (2004), A comparison of lung function methods for assessing dose-response effects of salbutamol. Br. J. Clin. Pharmacol. 58, 134-141.
59. Israel, E., Chinchilli, V. M., Ford, J. G., et al. (2004), Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet 364, 1505-1512.
60. Adler, A., Uziel, Y., Mei-Zahav, M., and Horowitz, I. (2006), Formoterol induces tolerance to the bronchodilating effect of salbutamol following methacholine-provocation test in asthmatic children. Pulmon. Pharmacol. Therapeut. 19, 281-285.
61. Shrewsbury, S., Pyke, S., and Britton, M. (2000), Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA). BMJ 320, 1368-1373.
62. Pauwels, R. A., Lofdahl, C. G., Postma, D. S., et al. (1997), Effect of inhaled formoterol and budesonide on exacerbations of asthma. N. Engl. J. Med. 337, 1405-1411.
63. Castle, W., Fuller, R., Hall, J., and Palmer, J. (1993), Serevent nationwide surveillance study: comparison of salmeterol with salbutamol in asthmatic patients who require regular bronchodilator therapy. BMJ 306, 1034-1037.
64. Mann, M., Chowdhury, B., Sullivan, E., Nicklas, R. A., Anthracite, R., and Meyer, R. J. (2003), Serious asthma exacerbations in asthmatics treated with high-dose formoterol. Chest 124, 70-74.