The β-adrenoceptor

American Journal of Respiratory and Critical Care Medicine

Volumn 158, Issue 5 III, 1998, Pages

  Johnson, Malcolm ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; RETINA S ANTIGEN; SALBUTAMOL; SALMETEROL;

ASTHMA; BETA ADRENERGIC STIMULATION; BRONCHODILATATION; CALCIUM CELL LEVEL; CONFERENCE PAPER; DRUG RECEPTOR BINDING; DRUG SENSITIVITY; GENETIC POLYMORPHISM; HUMAN; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; SITE DIRECTED MUTAGENESIS;

EID: 0031730981     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.158.supplement_2.13tac110     Document Type: Conference Paper

References (15)

1. 2-adrenergic receptor: a protein with multiple spanning domains and encoded by a gene whose chromosomal location is shared with that of a receptor for platelet growth factor. Proc. Natl. Acad. Sci. U.S.A. 84:46-50.
2. Henderson, R., J. M. Baldwin, T. A. Ceska, F. Zemlin, E. Beckmann, and K. H. Downing. 1990. Model for the structure of bacteriorhodopsin based on high-resolution electron cyro-microscopy. J. Mol. Biol. 213:899-929.
3. 2-adrenergic receptors. Proc. Natl. Acad. Sci. U.S.A. 85: 9494-9498.
4. Johnson, M. 1992. Mechanisms of action of β-adrenoceptor agonists. In J. F. Costello and R. D. Mann, editors. Beta-Agonists in the Treatment of Asthma. Parthenon, Carnforth. 27-42.
5. Spina, D., R. J. Rigby, J. W. Paterson, and R. G. Goldie. 1989. Autoradiographic localization of β-adrenoceptors in asthmatic human lung. Am. Rev. Respir. Dis. 140:1410-1415.
6. Huffman, E. A., R. Chiplunkar, and T. B. Casale. 1997. CT scanning confirms beta receptor distribution is greater for small versus large airways (abstract). Am. J. Respir. Crit. Care Med. 155:A855.
7. Martinsson, A., K. Larsson, and P. Hjemdahl. 1987. Studies in vivo and in vitro of terbutaline-induced beta-adrenoceptor desensitization in healthy subjects. Clin. Sci. 72:47-54.
8. 11C-CGP12177 and PET. J. Appl. Physiol. 75:559-565.
9. Qing, F., S. U. Rahman, C. G. Rhodes, M. Hayes, P. W. Ind, and J. M. Hughes. 1997. β-Adrenergic receptors in vivo and lung function in drug-free asthmatic subjects (abstract). Am. J. Respir. Crit. Care Med. 155:A855.
10. 2-adrenoceptor (abstract). Am. J. Respir. Crit. Care Med. 153.-A240.
11. Robison, G. A., R. W. Butcher, and E. W. Sutherland. 1967. Adenyl cyclase as an adrenergic receptor. Ann. N.Y. Acad. Sci. 319:703-723.
12. Onaran, H. O., T. Costa, and D. Rodbard. 1993. Subunits of guanine nucleotide-binding proteins and regulation of spontaneous receptor activity: thermodynamic model for the interaction between receptors and guanine nucleotide-binding protein subunits. Mol. Pharmacol. 43:245-256.
13. Costa, T., Y. Ogino, P. J. Munson, H. O. Onaran, and D. Rodbard. 1992. Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand. Mol. Pharmacol. 41:549-560.
14. 2-adrenoceptor agonists. In W. W. Busse and S. T. Holgate, editors. Asthma and Rhinitis. Blackwell, Cambridge. 1278-1295.
15. +-channels in trachealis muscle. Br. J. Pharmacol. 109:1140-1148.