What intervals in oral therapy of isosorbide dinitrate various doses are sufficient to prevent nitrate tolerance?

Medical Science Monitor

Volumn 6, Issue 4, 2000, Pages 763-768

  Kosmicki, M ^a   Sadowski, Z ^a   Szwed, H ^a   Kowalik, L ^a  

^a INSTITUTE OF CARDIOLOGY   (Poland)

Author keywords

Exercise stress testing; Nitrates; Stable angina pectoris

Indexed keywords

ISOSORBIDE DINITRATE;

ADULT; ANGINA PECTORIS; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG INTERMITTENT THERAPY; DRUG TOLERANCE; EXERCISE TOLERANCE; HEART MUSCLE ISCHEMIA; HUMAN; LONG TERM CARE; MALE;

ADMINISTRATION, ORAL; ADULT; ANGINA PECTORIS; CROSS-OVER STUDIES; DELAYED-ACTION PREPARATIONS; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; DRUG TOLERANCE; EXERCISE TEST; HUMANS; ISOSORBIDE DINITRATE; MALE; MIDDLE AGED; TIME FACTORS; VASODILATOR AGENTS;

EID: 0033851109     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

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2. Kinetics of isosorbide dinitrate and relationship to pharmacological effects
3. Prospects for therapy of nitrate tolerance
4. Rationale for intermittent nitrate therapy
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6. Clinical mechanisms of nitrate action
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11. Phenomenon of nitrate tolerance
12. Nitrate therapy for stable angina pectoris
13. Oral isosorbide dinitrate in angina pectoris: Comparison of duration of action and dose - Response relation during acute and sustained therapy
14. Effects of acute and chronic administration of isosorbide dinitrate, sustained - Release form, in patients with angina pectoris
15. Organic nitrates: Relationship between biotransformation and rational angina pectoris therapy
16. Tolerance: An historical overview
17. Nitrate tolerance. Letter to the Editor