Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets

Oncogene

Volumn 25, Issue 55, 2006, Pages 7267-7273

  Ferretti, E ^a   Di Marcotullio, L ^a   Gessi, M ^b   Mattei, T ^a   Greco, A ^a   Po, A ^a   De Smaele, E ^a   Giangaspero, F ^a,c   Riccardi, R ^d   Di Rocco, C ^e   Pazzaglia, S ^f   Maroder, M ^a   Alimandi, M ^a   Screpanti, I ^a,g   Gulino, A ^a,c  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b DEPARTMENT OF NEUROSURGERY   (Italy)

^c IRCCS NEUROMED   (Italy)

^d CATHOLIC UNIVERSITY   (Italy)

^e CATHOLIC UNIVERSITY   (Italy)

^f ENEA C R CASACCIA   (Italy)

^g Pasteur Institute   (Italy)

Author keywords

Alternative splicing; ErbB 4; Gli1; Hedgehog; Medulloblastoma

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 4; EPIDERMAL GROWTH FACTOR RECEPTOR 4 CYT 1; EPIDERMAL GROWTH FACTOR RECEPTOR 4 CYT 2; ETOPOSIDE; NEU DIFFERENTIATION FACTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; HUMAN; HUMAN TISSUE; MEDULLOBLASTOMA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; CYTOPLASM; DNA PRIMERS; HEDGEHOG PROTEINS; HUMANS; MEDULLOBLASTOMA; MICE; PROGNOSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ERINACEIDAE;

EID: 33751307615     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209716     Document Type: Article

References (29)

1. Argenti B, Gallo R, Di Marcotullio L, Ferretti E, Napolitano M, Canterini S et al. (2005). J Neurosci 25: 8338-8346.
2. Carpenter G. (2003). Exp Cell Res 284: 66-77.
3. Di Marcotullio L, Ferretti E, De Smaele E, Argenti B, Mincione C, Zazzeroni F et al. (2004). Proc Natl Acad Sci USA 101: 10833-10838.
4. Elenius K, Choi CJ, Paul S, Santiestevan E, Nishi E, Klagsbrun M. (1999). Oncogene 18: 2607-2615.
5. Elenius K, Corfas G, Paul S, Choi CJ, Rio C, Plowman GD et al. (1997). J Biol Chem 272: 26761-26768.
6. Ferretti E, De Smaele E, Di Marcotullio L, Screpanti I, Gulino A. (2005). Trends Mol Med 11: 537-545.
7. Fox IJ, Kornblum HI. (2005). J Neurosci Res 79: 584-597.
8. Gajjar A, Hernan R, Kocak M, Fuller C, Lee Y, McKinnon PJ et al. (2004). J Clin Oncol 22: 984-993.
9. Gambarotta G, Garzotto D, Destro E, Mautino B, Giampietro C, Cutrupi S et al. (2004). J Biol Chem 279: 48808-48816.
10. Giangaspero F, Bigner SH, Kleihues P, Pietsch T, Trojanowski JQ. (2002). In: Kleihues P, Cavenee WK (eds). Pathology and Genetics Tumors of Nervous System: Medulloblastoma. IARC Press: Lyon, pp 129-137.
11. Gilbertson R, Hernan R, Pietsch T, Pinto L, Scotting P, Allibone R et al. (2001). Genes Chromosomes Cancer 31: 288-294.
12. Gilbertson RJ, Clifford SC, MacMeekin W, Meekin W, Wright C, Perry RH et al. (1998). Cancer Res 58: 3932-3941.
13. Gilbertson RJ, Perry RH, Kelly PJ, Pearson AD, Lunec J. (1997). Cancer Res 57: 3272-3280.
14. Hahn H, Wojnowski L, Zimmer AM, Hall J, Miller G, Zimmer A. (1998). Nat Med 4: 619-622.
15. Junttila TT, Laato M, Vahlberg T, Soderstrom KO, Visakorpi T, Isola J et al. (2003). Clin Cancer Res 9: 5346-5357.
16. Junttila TT, Sundvall M, Lundin M, Lundin J, Tanner M, Harkonen P et al. (2005). Cancer Res 65: 1384-1393.
17. Junttila TT, Sundvall M, Maattaa J, Elenius K. (2000). Trends Cardiovasc Med 10: 304-310.
18. Kainulainen V, Sundvall M, Maatta JA, Santiestevan E, Klagsbrun M, Elenius K. (2000). J Biol Chem 275: 8641-8649.
19. Martì E, Bovolenta P. (2002). Trends Neurosci 2: 89-96.
20. Ni CY, Murphy MP, Golde TE, Carpenter G. (2001). Science 294: 2179-2181.
21. Omerovic J, Puggioni EM, Napoletano S, Visco V, Fraioli R, Frati L et al. (2004). Exp Cell Res 294: 469-479.
22. Ozaki M, Kishigami S, Yano R. (1998). Neurosci Res 30: 351-354.
23. Pazzaglia S, Mancuso M, Atkinson MJ, Tanori M, Rebessi S, Majo VD et al. (2002). Oncogene 21: 7580-7584.
24. Rieff HI, Raetzman LT, Sapp DW, Yeh HH, Siegel RE, Corfas G. (1999). J Neurosci 19: 10757-10766.
25. Ruiz i Altaba A, Sanchez P, Dahmane N. (2002). Nat Rev Cancer 2: 361-382.
26. Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L et al. (2000). Nature 406: 1005-1009.
27. Tidcombe H, Jackson-Fisher A, Mathers K, Stern DF, Gassmann M, Golding JP. (2003). Proc Natl Acad Sci USA 100: 8281-8286.
28. Yarden Y, Sliwkowski MX. (2001). Nat Rev Mol Cell Biol 2: 127-137.
29. Zhang D, Sliwkowski MX, Mark M, Frantz G, Akita R, Sun Y et al. (1997). Proc Natl Acad Sci USA 94: 9562-9567.