Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols

Journal of Pharmacy and Pharmacology

Volumn 58, Issue 11, 2006, Pages 1533-1543

  Zhong, Zhi ^a   Connor, Henry D ^b   Li, Xiangli ^c   Mason, Ronald P ^b   Forman, Donald T ^c   Lemasters, John J ^a   Thurman, Ronald G ^c  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYNONENAL; CAMELLIA SINENSIS EXTRACT; CYCLOSPORIN; DIMETHYL SULFOXIDE; FREE RADICAL; HYDROXYL RADICAL; N TERT BUTYL ALPHA (4 PYRIDYL 1 OXIDE) NITRONE; PLANT EXTRACT; POLYPHENOL DERIVATIVE; TSUKUBAENOLIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VACUOLE; CONTROLLED STUDY; DRUG EFFECT; ELECTRON SPIN RESONANCE; GLOMERULUS FILTRATION RATE; HYALINE DEGENERATION; KIDNEY CALCIFICATION; KIDNEY FUNCTION; LIPID PEROXIDATION; MALE; NEPHROTOXICITY; NONHUMAN; RAT; RENAL PROTECTION; TEA;

ALDEHYDES; ANIMALS; CAMELLIA SINENSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOSPORINE; FLAVONOIDS; FREE RADICALS; GLOMERULAR FILTRATION RATE; GLYCEROL; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; KIDNEY DISEASES; MALE; PHENOLS; PHYTOTHERAPY; PLANT OILS; RATS; RATS, SPRAGUE-DAWLEY; TACROLIMUS;

EID: 33751228990     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.58.11.0015     Document Type: Article

References (52)

1. Andoh, T. F., Birdman, E. A., Fransechini, N., Houghton, D. C., Bennett, W. M. (1996) Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506. Kidney Int. 50: 1110-1117
2. Borel, J. F., Feurer, C., Gubler, H. U., Stahelin, H. (1976) Biological effects of cyclosporin A: a new antilymphocytic agent. Agents Actions 6: 468-475
3. Burkitt, M. J., Mason, R. P. (1991) Direct evidence for in vivo hydroxyl-radical generation in experimental iron-overload: an ESR spin-trapping investigation. Proc. Natl Acad. Sci. USA 88:8440-8444
4. Calo, L. A., Davis, P. A., Giacon, B. Pagnin, E., Sartori, M., Riegler, P., Antonello, A., Huber, W., Semplicini, A. (2002) Oxidative stress in kidney transplant patients with calcineurin inhibitor-induced hypertension: effect of ramipril. J. Cardiovasc. Pharmacol. 40: 625-631
5. Chung, B. H., Li, C., Sun, B. K., Lim, S. W., Ahn, K. O., Yang, J. H., Choi, Y. H., Yoon, K. H., Sugawara, A., Ito, S., Kim, J., Yang, C. W. (2005) Rosiglitazone protects against cyclosporine-induced pancreatic and renal injury in rats. Am. J. Transplant. 5: 1856-1867
6. 4 by the perfused rat liver and in vivo. J. Biol. Chem. 261:4542-4548
7. Duggin, G. G., Baxter, C., Hall, B. M., Horvath, J. S., Tiller, D. J. (1986) Influence of cyclosporine A (CSA) on intrarenal control of GFR. Clin. Nephrol. 25 (Suppl. 1): S43-S45
8. Duling, D. R. (1994) Simulation on multiple isotropic spin-trap EPR spectra. J. Magnetic Resonance 104:105-110
9. English, J., Evan, A., Houghton, D. C., Bennett, W. M. (1987) Cyclosporine-induced acute renal dysfunction in the rat. Transplantation 44: 135-141
10. Farthing, M. J. G., Clark, M. L. (1981) Nature of the toxicity of cyclosporin A in the rat. Biochem. Pharmacol. 24: 3311-3316
11. Ferrali, M., Fulceri, R., Benedetti, A., Comporti, M. (1980) Effects of carbonyl compounds (4-hydroxyalkenals) originating from the peroxidation of liver microsomal lipids on various microsomal enzyme activities of the liver. Res. Commun. Chem. Pathol. Pharmacol. 30: 99-112
12. Frankel, E. N. (1999) Natural phenolic antioxidants and their impact on health. In: Lester, P., Hiramastu, M., Yoshikawa, T. (eds) Antioxidant food supplements in human health. Academic Press, San Diego, pp 385-392
13. Fung, J. J., Alessiani, M., Abu-Elmagd, K., Todo, S., Shapiro, R., Tzakis, A., van Thiel, D., Armitage, J., Jain, A., McCauley, J. (1991) Adverse effects associated with the use of FK 506. Transplant. Proc. 23: 3105-3108
14. Gupta, S., Ahmad, N., Mohan, R. R., Husain, M. M., Mukhtar, H. (1999) Prostate cancer chemoprevention by green tea: in vitro and in vivo inhibition of testosterone-mediated induction of ornithine decarboxylase. Cancer Res. 59: 2115-2120
15. Hara, Y. (1994) Antioxidative action of tea polyphenols: part 1. Am. Biotechnol. Lab. 12: 48
16. Harding, M. W., Galat, A., Uehling, D. E., Schreiber, S. L. (1989) A receptor for the immunosuppressant FK506 is a cis-trans peptidylprolyl isomerase. Nature 341: 758-760
17. Kada, T., Kaneko, K., Matsuzaki, S., Matsuzaki, T., Hara, Y. (1985) Detection and chemical identification of natural bio-antimutagens. A case of the green tea factor. Mutat. Res. 150: 127-132
18. Kino, T., Hatanaka, H., Miyata, S., Inamura, N., Nishiyama, M., Yajima, T., Goto, T., Okuhara, M., Kohsaka, M., Aoki, H. (1987) FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. J. Antibiot. (Tokyo) 40: 1256-1265
19. Knecht, K. T., Bradford, B. U., Mason, R. P., Thurman, R. G. (1990) In vivo formation of a free radical metabolite of ethanol. Mol. Pharmacol. 38: 26-30
20. Kon, V., Sugiura, M., Inagami, T., Harvie, B. R., Ichikawa, I., Hoover, R. L. (1990) Role of endothelin in cyclosporine-induced glomerular dysfunction. Kidney Int. 37: 1487-1491
21. Laiken, N. D., Fanestil, D. D. (1985) Body fluids and renal function. In: West, J. B. (ed.) Physiological basis of medical practice. Williams & Wilkins, Baltimore/London, pp 438-543
22. Lin, A. M., Chyi, B. Y., Wu, L. Y., Hwang, L. S., Ho, L. T. (1998) The antioxidative property of green tea against iron-induced oxidative stress in rat brain. CAm. J. Physiol. 41: 189-194
23. Lyson, T., Ermel, L. D., Belshaw, P. J., Alberg, D. G., Schreiber, S. L., Victor, R. G. (1993) Cyclosporine- and FK 506-induced sympathetic activation correlates with calcineurin-mediated inhibition of T-cell signaling. Circ. Res. 73: 596-602
24. Margreiter, R., Huber, C., Spielberger, M., Konig, P. (1983) Cyclosporine in the treatment of acute cadaveric kidney graft rejection refractory to high-dose methylprednisolone. Transplantation 36: 203-204
25. Mehring, N., Neumann, K.-H., Rahn, K.-H., Zidek, W. (1992) Mechanisms of cyclosporin A-induced vasoconstriction in the isolated perfused rat kidney. Nephron 60: 477-481
26. Mitamura, T., Yamada, A., Ishida, H., Fujihira, S., Ohara, K., Noguchi, H., Mine, Y. (1994) Tacrolimus (FK506)-induced nephrotoxicity in spontaneous hypertensive rats. J. Toxicol. Sci. 19: 219-226
27. Miyagawa, C., Wu, C., Kennedy, D. O., Nakatani, T., Ohtani, K., Sakanaka, S., Kim, M., Matsui-Yuasa, I. (1997) Protective effect of green tea extract and tea polyphenols against the cytotoxicity of 1,4-naphthoquinone in isolated rat hepatocytes. Biosci. Biotechnol. Biochem. 61: 1901-1905
28. Mohamadin, A. M., El Beshbishy, H. A., El Mahdy, M. A. (2005) Green tea extract attenuates cyclosporine A-induced oxidative stress in rats. Pharmacol. Res. 51: 51-57
29. Moss, N. G., Powell, S. L., Falk, R. J. (1985) Intravenous cyclosporine activates afferent and efferent renal nerves and causes sodium retention in innervated kidneys in rats. Proc. Natl Acad. Sci. USA 82: 8222-8226
30. Moutabarrik, A., Ishibashi, M., Fukunaga, M., Kameoka, H., Takano, Y., Kokado, Y., Takahara, S., Jiang, H., Sonoda, T., Okuyama, A. (1992) FK506-induced kidney tubular cell injury. Transplantation 54: 1041-1047
31. Moyer, T. P., Winkels, J., Krom, R., Wiesner, R. (1991) Evaluation of Abbott TDx monoclonal assay of cyclosporine in whole blood. Clin. Chem. 31: 1120-1121
32. Muramatsu, K., Fukuyo, M., Hara, Y. (1986) Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats. J. Nutr. Sci. Vitaminol. (Tokyo) 32: 613-622
33. Nemlander, A., Andersson, L. C., Hayry, P. (1979) Rat mixed lymphocyte culture: optimization of culture conditions. Scand. J. Immunol. 10: 437-446
34. Ruch, R. J., Cheng, S. J., Klaunig, J. E. (1989) Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis 10: 1003-1008
35. Serafini, M., Ghiselli, A., Ferro-Luzzi, A. (1996) In vivo antioxidant effect of green and black tea in man. Eur. J. Clin. Nutr. 50: 28-32
36. Shen, X., Lu, R., Wu, M. (1998) Effects of tea polyphenol on blood lipid and antioxidation in vivo in aged rats. Chung Hua Yu Fang I. Hsueh Tsa Chih 32: 34-36
37. Shihab, F. S., Bennett, W. M., Yi, H., Andoh, T. F. (2005) Effect of pirfenidone on apoptosis-regulatory genes in chronic cyclosporine nephrotoxicity. Transplantation 79: 419-426
38. Sibley, R. K., Rynasiewicz, J., Ferguson, R. M., Fryd, D., Sutherland, D. E., Simmons, R. L., Najarian, J. S. (1983) Morphology of cyclosporine nephrotoxicity and acute rejection in patients immunosuppressed with cyclosporine and prednisone. Surgery 94: 225-234
39. Sohn, O. S., Surace, A., Fiala, E. S., Richie, J. P., Colosimo, S., Zang, E., Weisburger, J. H. (1994) Effects of green and black tea on hepatic xenobiotic metabolizing systems in the male F344 rat. Xenobiotica 24: 119-127
40. Starzl, T. E., Fung, J., Venkataramman, R., Todo, S., Demetris, A. J., Jain, A. (1989) FK 506 for liver, kidney, and pancrease transplantation. Lancet 28: 1000-1004
41. Su, Q., Weber, L., Le Hir, M., Zenke, G., Ryffel, B. (1995) Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase. Ren. Physiol. Biochem. 18: 128-139
42. Tamura, K., Kobayashi, M., Hashimoto, K., Kojima, K., Nagase, K., Iwasaki, K., Kaizu, T., Tanaka, H., Niwa, M. (1987) A highly sensitive method to assay FK-506 levels in plasma. Transplant. Proc. 19: 23-29
43. Undre, N. A., Stevenson, P., Schafer, A. (1999) Pharmacokinetics of tacrolimus: clinically relevant aspects. Transplant. Proc. 31:21S-24S
44. Vinson, J. A. (2000) Black and green tea and heart disease: a review. Biofactors 13: 127-132
45. Vinson, J. A., Dabbagh, Y. A. (1998) Effect of green and black tea supplementation on lipids, lipid oxidation and fibrinogen in the hamster: mechanisms for the epidemiological benefits of tea drinking. FEBS Lett. 433: 44-46
46. Wang, Z. Y., Khan, W. A., Bickers, D. R., Mukhtar, H. (1989) Protection against polycyclic aromatic hydrocarbon-induced skin tumor initiation in mice by green tea polyphenols. Carcinogenesis 10:411-415
47. Wood, A. J., Mauer, G., Niederberger, W., Beveridge, T. (1983) Cyclosporine: Pharmacokinetics, metabolism, and drug interactions. Transplant. Proc. 15: 2409-2412
48. Yoshino, M., Murakami, K. (1998) Interaction of iron with polyphenolic compounds: application to antioxidant characterization. Anal. Biochem. 257: 40-44
49. Yoshioka, N., Hiasa, Y., Cho, M., Kitahori, Y., Hirao, K., Konishi, N., Kuwashima, S. (1999) Effect of polyphenon-60 on the development of renal cell tumors in rats treated with N-ethyl-N hydroxyethylnitrosamine. Cancer Lett. 136: 79-82
50. Zhong, Z., Arteel, G. E., Connor, H., Yin, M., Frankenberg, M. V., Stachlewitz, R. F., Raleigh, J. A., Mason, R. P., Thurman, R. G. (1998) Cyclosporin A increases hypoxia and free radical production in the rat kidney: prevention by dietary glycine. Am. J. Physiol. 275: F595-F604
51. Zhong, Z., Connor, H. D., Yin, M., Moss, N., Mason, R. P., Bunzendahl, H., Forman, D. T., Thurman, R. G. (1999) Dietary glycine and renal denervation prevents cyclosporin A-induced hydroxyl radical production in rat kidney. Mol. Pharmacol. 56: 455-463
52. Zhong, Z., Froh, M., Connor, H. D., Li, X. L., Conzelmann, L. O., Mason, R. P., Lemasters, J. J., Thurman, R. G. (2002) Prevention of hepatic ischemia-reperfusion injury by green tea extract. Am. J. Physiol. 283: G957-G964