-
1
-
-
0029806297
-
Chronic cyclosporine nephropathy: The Achilles' heel of immunosuppressive therapy
-
Bennett WM, DeMattos A, Meyer MM, et al. Chronic cyclosporine nephropathy: the Achilles' heel of immunosuppressive therapy. Kidney Int 1996; 50: 1089.
-
(1996)
Kidney Int
, vol.50
, pp. 1089
-
-
Bennett, W.M.1
Demattos, A.2
Meyer, M.M.3
-
2
-
-
0029857451
-
Cyclosporine nephropathy: Pathophysiology and clinical impact
-
Shihab FS. Cyclosporine nephropathy: pathophysiology and clinical impact. Semin Nephrol 1996; 16: 536.
-
(1996)
Semin Nephrol
, vol.16
, pp. 536
-
-
Shihab, F.S.1
-
3
-
-
0029923855
-
Role of transforming growth factor-β1 in experimental chronic cyclosporine nephropathy
-
Shihab FS, Andoh TF, Tanner AM, et al. Role of transforming growth factor-β1 in experimental chronic cyclosporine nephropathy. Kidney Int 1996; 49: 1141.
-
(1996)
Kidney Int
, vol.49
, pp. 1141
-
-
Shihab, F.S.1
Andoh, T.F.2
Tanner, A.M.3
-
4
-
-
0030801946
-
Angiotensin II blockade decreases TGF-β1 and matrix proteins in chronic cyclosporine nephropathy
-
Shihab FS, Bennett WM, Tanner AM, et al. Angiotensin II blockade decreases TGF-β1 and matrix proteins in chronic cyclosporine nephropathy. Kidney Int 1997; 52: 660.
-
(1997)
Kidney Int
, vol.52
, pp. 660
-
-
Shihab, F.S.1
Bennett, W.M.2
Tanner, A.M.3
-
5
-
-
0033856295
-
Effect of nitric oxide modulation on TGF-β1 and matrix proteins in chronic cyclosporine nephrotoxicity
-
Shihab FS, Yi H, Bennett WM, et al. Effect of nitric oxide modulation on TGF-β1 and matrix proteins in chronic cyclosporine nephrotoxicity. Kidney Int 2000; 58: 1174.
-
(2000)
Kidney Int
, vol.58
, pp. 1174
-
-
Shihab, F.S.1
Yi, H.2
Bennett, W.M.3
-
6
-
-
0347996179
-
Pirfenidone treatment decreases transforming growth factor-β1 and matrix proteins and ameliorates fibrosis in chronic cyclosporine nephrotoxicity
-
Shihab FS, Bennett WM, Yi H, et al. Pirfenidone treatment decreases transforming growth factor-β1 and matrix proteins and ameliorates fibrosis in chronic cyclosporine nephrotoxicity. Am J Transplant 2002; 2: 111.
-
(2002)
Am J Transplant
, vol.2
, pp. 111
-
-
Shihab, F.S.1
Bennett, W.M.2
Yi, H.3
-
7
-
-
0033405266
-
Expression of apoptosis regulatory genes in chronic cyclosporine nephrotoxicity favors apoptosis
-
Shihab FS, Andoh TF, Tanner AM, et al. Expression of apoptosis regulatory genes in chronic cyclosporine nephrotoxicity favors apoptosis. Kidney Int 1999; 56: 2147.
-
(1999)
Kidney Int
, vol.56
, pp. 2147
-
-
Shihab, F.S.1
Andoh, T.F.2
Tanner, A.M.3
-
8
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S. Apoptosis by death factor. Cell 1997; 88: 355.
-
(1997)
Cell
, vol.88
, pp. 355
-
-
Nagata, S.1
-
9
-
-
0348226836
-
Role of apoptosis in hypoxic/ischemic damage in the kidney
-
Saikumar P, Venkatachalam MA. Role of apoptosis in hypoxic/ischemic damage in the kidney. Semin Nephrol 2003; 23: 511.
-
(2003)
Semin Nephrol
, vol.23
, pp. 511
-
-
Saikumar, P.1
Venkatachalam, M.A.2
-
10
-
-
0141922638
-
Implication of apoptosis in progression of renal diseases
-
Kashihara N, Sugiyama H, Makino H. Implication of apoptosis in progression of renal diseases. Contrib Nephrol 2003; 139: 156.
-
(2003)
Contrib Nephrol
, vol.139
, pp. 156
-
-
Kashihara, N.1
Sugiyama, H.2
Makino, H.3
-
11
-
-
0036256227
-
Role of apoptosis in the pathogenesis of acute renal failure
-
Bonegio R, Lieberthal W. Role of apoptosis in the pathogenesis of acute renal failure. Curr Opin Nephrol Hypertens 2002; 11: 301.
-
(2002)
Curr Opin Nephrol Hypertens
, vol.11
, pp. 301
-
-
Bonegio, R.1
Lieberthal, W.2
-
12
-
-
0028473454
-
Apoptosis and the kidney
-
Savill J. Apoptosis and the kidney. J Am Soc Nephrol 1994; 5: 12.
-
(1994)
J Am Soc Nephrol
, vol.5
, pp. 12
-
-
Savill, J.1
-
13
-
-
0036589946
-
Expression of apoptosis-related genes in chronic cyclosporine nephrotoxicity in mice
-
Yang CW, Faulkner GR, Wahba IM, et al. Expression of apoptosis-related genes in chronic cyclosporine nephrotoxicity in mice. Am J Transplant 2002; 2: 391.
-
(2002)
Am J Transplant
, vol.2
, pp. 391
-
-
Yang, C.W.1
Faulkner, G.R.2
Wahba, I.M.3
-
14
-
-
0031773717
-
Cyclosporine a induces apoptosis in murine tubular epithelial cells: Role of caspases
-
Ortiz A, Lorz C, Catalan M, et al. Cyclosporine A induces apoptosis in murine tubular epithelial cells: role of caspases. Kidney Int 1998; 68: S25.
-
(1998)
Kidney Int
, vol.68
-
-
Ortiz, A.1
Lorz, C.2
Catalan, M.3
-
15
-
-
0029318974
-
Dietary intake of pirfenidone ameliorates bleomycin induced lung fibrosis in hamsters
-
Iyer SN, Wild JS, Schiedt MJ, et al. Dietary intake of pirfenidone ameliorates bleomycin induced lung fibrosis in hamsters. J Lab Clin Med 1995; 125: 779.
-
(1995)
J Lab Clin Med
, vol.125
, pp. 779
-
-
Iyer, S.N.1
Wild, J.S.2
Schiedt, M.J.3
-
16
-
-
0032926937
-
Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: Results of a prospective, open-label phase II study
-
Raghu G, Johnson WC, Lockhart D, et al. Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: results of a prospective, open-label phase II study. Am J Respir Crit Care Med 1999; 159: 1061.
-
(1999)
Am J Respir Crit Care Med
, vol.159
, pp. 1061
-
-
Raghu, G.1
Johnson, W.C.2
Lockhart, D.3
-
17
-
-
0036844834
-
Effect of pirfenidone on rat hepatic stellate cell proliferation and collagen production
-
Di Sario A, Bendia E, Svegliati Baroni G, et al. Effect of pirfenidone on rat hepatic stellate cell proliferation and collagen production. J Hepatol 2002; 37: 584.
-
(2002)
J Hepatol
, vol.37
, pp. 584
-
-
Di Sario, A.1
Bendia, E.2
Svegliati Baroni, G.3
-
18
-
-
0036185827
-
Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats
-
Mirkovic S, Seymour AM, Fenning A, et al. Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats. Br J Pharmacol 2002; 135: 961.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 961
-
-
Mirkovic, S.1
Seymour, A.M.2
Fenning, A.3
-
19
-
-
0032753414
-
Chronic progressive interstitial fibrosis in renal disease - Are there novel pharmacologic approaches?
-
Fukagawa M, Noda M, Shimizu T, et al. Chronic progressive interstitial fibrosis in renal disease - are there novel pharmacologic approaches? Nephrol Dial Transplant 1999; 14: 2793.
-
(1999)
Nephrol Dial Transplant
, vol.14
, pp. 2793
-
-
Fukagawa, M.1
Noda, M.2
Shimizu, T.3
-
20
-
-
0030822476
-
Pirfenidone prevents the progression of irreversible glomerular sclerotic lesions
-
Shimizu F, Fukagawa M, Yamauchi S, et al. Pirfenidone prevents the progression of irreversible glomerular sclerotic lesions. Nephrol 1997; 3: 315.
-
(1997)
Nephrol
, vol.3
, pp. 315
-
-
Shimizu, F.1
Fukagawa, M.2
Yamauchi, S.3
-
21
-
-
0031474029
-
Pirfenidone prevents collagen accumulation in the remnant kidney in rats with partial nephrectomy
-
Shimizu T, Fukagawa M, Kuroda T, et al. Pirfenidone prevents collagen accumulation in the remnant kidney in rats with partial nephrectomy. Kidney Int 1997; 52: S239.
-
(1997)
Kidney Int
, vol.52
-
-
Shimizu, T.1
Fukagawa, M.2
Kuroda, T.3
-
22
-
-
0031834709
-
Pirfenidone improves renal function and fibrosis in the post-obstructed kidney
-
Shimizu T, Kuroda T, Hata S, et al. Pirfenidone improves renal function and fibrosis in the post-obstructed kidney. Kidney Int 1998; 54: 99.
-
(1998)
Kidney Int
, vol.54
, pp. 99
-
-
Shimizu, T.1
Kuroda, T.2
Hata, S.3
-
23
-
-
0031738215
-
Pirfenidone: A novel pharmacological agent that inhibits leiomyoma cell proliferation and collagen production
-
Lee BS, Margolin SB, Nowak RA. Pirfenidone: a novel pharmacological agent that inhibits leiomyoma cell proliferation and collagen production. J Clin Endocrinol Metab 1998; 83: 219.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 219
-
-
Lee, B.S.1
Margolin, S.B.2
Nowak, R.A.3
-
24
-
-
0031663187
-
Pirfenidone: A novel antifibrotic agent with implications for the treatment of obliterative bronchiolitis
-
Dosanjh AK, Wan B, Throndset W, et al. Pirfenidone: a novel antifibrotic agent with implications for the treatment of obliterative bronchiolitis. Transplant Proc 1998; 30: 1910.
-
(1998)
Transplant Proc
, vol.30
, pp. 1910
-
-
Dosanjh, A.K.1
Wan, B.2
Throndset, W.3
-
25
-
-
0031820998
-
Pirfenidone induces intercellular adhesion molecule-1 (ICAM-1) downregulation on cultured human synovial fibroblasts
-
Kaneko M, Inoue H, Nakazawa R, et al. Pirfenidone induces intercellular adhesion molecule-1 (ICAM-1) downregulation on cultured human synovial fibroblasts. Clin Exp Immunol 1998; 113: 72.
-
(1998)
Clin Exp Immunol
, vol.113
, pp. 72
-
-
Kaneko, M.1
Inoue, H.2
Nakazawa, R.3
-
26
-
-
0031914475
-
Lung fibrosis is ameliorated by pirfenidone fed in diet after the second dose in a three dose bleomycin hamster model
-
Iyer SN, Margolin SB, Hyde DM, et al. Lung fibrosis is ameliorated by pirfenidone fed in diet after the second dose in a three dose bleomycin hamster model. Exp Lung Res 1998; 24: 119.
-
(1998)
Exp Lung Res
, vol.24
, pp. 119
-
-
Iyer, S.N.1
Margolin, S.B.2
Hyde, D.M.3
-
27
-
-
0031957453
-
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis
-
Thomas SE, Andoh TF, Pichler RH, et al. Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis. Kidney Int 1998; 53: 897.
-
(1998)
Kidney Int
, vol.53
, pp. 897
-
-
Thomas, S.E.1
Andoh, T.F.2
Pichler, R.H.3
-
28
-
-
0027298576
-
Induction of cellular p53 activity by DNA damaging agents and growth arrest
-
Zhan Q, Carrier F, Fornace AJ. Induction of cellular p53 activity by DNA damaging agents and growth arrest. Mol Cell Biol 1993; 13: 4242.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4242
-
-
Zhan, Q.1
Carrier, F.2
Fornace, A.J.3
-
29
-
-
0027319521
-
p53 is required for radiation induced apoptosis in mouse thymocytes
-
Lowe SW, Scmitt EM, Smith SW, et al. p53 is required for radiation induced apoptosis in mouse thymocytes. Nature 1993; 362: 847.
-
(1993)
Nature
, vol.362
, pp. 847
-
-
Lowe, S.W.1
Scmitt, E.M.2
Smith, S.W.3
-
30
-
-
0029887283
-
The effect of ACE inhibitors on the expression of matrix genes and the role of p53 and p21 (WAF1) in experimental renal fibrosis
-
Morrissey JJ, Ishidoya S, McCracken R, et al. The effect of ACE inhibitors on the expression of matrix genes and the role of p53 and p21 (WAF1) in experimental renal fibrosis. Kidney Int 1996; 54: S83.
-
(1996)
Kidney Int
, vol.54
-
-
Morrissey, J.J.1
Ishidoya, S.2
McCracken, R.3
-
31
-
-
0030789576
-
Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis
-
Sandau K, Pfeilschifter J, Brüne B. Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis. Kidney Int 1997; 52: 378.
-
(1997)
Kidney Int
, vol.52
, pp. 378
-
-
Sandau, K.1
Pfeilschifter, J.2
Brüne, B.3
-
32
-
-
0031752760
-
Apoptosis and necrosis: Mechanisms of cell death induced by cyclosporine A in renal proximal tubular cell line
-
Healy E, Dempsey M, Lally C, et al. Apoptosis and necrosis: mechanisms of cell death induced by cyclosporine A in renal proximal tubular cell line. Kidney Int 1998; 54: 1955.
-
(1998)
Kidney Int
, vol.54
, pp. 1955
-
-
Healy, E.1
Dempsey, M.2
Lally, C.3
-
33
-
-
0031900627
-
Induction of apoptosis in ischemia-reperfusion model of mouse kidney: Possible involvement of Fas
-
Nogae S, Miyazaki M, Kobayashi N, et al. Induction of apoptosis in ischemia-reperfusion model of mouse kidney: possible involvement of Fas. J Am Soc Nephrol 1998; 9: 620.
-
(1998)
J Am Soc Nephrol
, vol.9
, pp. 620
-
-
Nogae, S.1
Miyazaki, M.2
Kobayashi, N.3
-
34
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
Hockenbery DM, Oltavi ZN, Yin X-M, et al. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993; 75: 241.
-
(1993)
Cell
, vol.75
, pp. 241
-
-
Hockenbery, D.M.1
Oltavi, Z.N.2
Yin, X.-M.3
-
35
-
-
0000789698
-
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
-
Hockenbery D, Nunez G, Milliman C, et al. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1992; 348: 384.
-
(1992)
Nature
, vol.348
, pp. 384
-
-
Hockenbery, D.1
Nunez, G.2
Milliman, C.3
-
36
-
-
0346059343
-
Pirfenidone prevents endotoxin-induced liver injury after partial hepatectomy in rats
-
Tsuchiya H, Kaibori M, Yanagida H, et al. Pirfenidone prevents endotoxin-induced liver injury after partial hepatectomy in rats. J Hepatol 2004; 40: 94.
-
(2004)
J Hepatol
, vol.40
, pp. 94
-
-
Tsuchiya, H.1
Kaibori, M.2
Yanagida, H.3
-
37
-
-
0026769457
-
Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor β1
-
Oberhammer FA, Pavelka M, Sharma S, et al. Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor β1. Proc Natl Acad Sci 1992; 89: 5408.
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 5408
-
-
Oberhammer, F.A.1
Pavelka, M.2
Sharma, S.3
-
38
-
-
0031568949
-
Angiotensin II activates programmed cell death in vitro
-
Cigola E, Kajstura J, Li B, et al. Angiotensin II activates programmed cell death in vitro. Exp Cell Res 1997; 231: 363.
-
(1997)
Exp Cell Res
, vol.231
, pp. 363
-
-
Cigola, E.1
Kajstura, J.2
Li, B.3
-
39
-
-
0031569094
-
2+ elevation and cyclosporine a synergistically induce TGF-β1-mediated apoptosis in lymphocytes
-
2+ elevation and cyclosporine A synergistically induce TGF-β1-mediated apoptosis in lymphocytes. J Immunol 1997; 158: 2527.
-
(1997)
J Immunol
, vol.158
, pp. 2527
-
-
Andjelic, S.1
Khanna, A.2
Suthanthiran, M.3
|