Effects of Cot expression on the nuclear translocation of NF-κB in RBL-2H3 cells

Molecular Immunology

Volumn 44, Issue 7, 2007, Pages 1490-1497

  Chikamatsu, Satomi ^a   Furuno, Tadahide ^a,b   Kinoshita, Yosuke ^a   Inoh, Yoshikazu ^b   Hirashima, Naohide ^a   Teshima, Reiko ^c   Nakanishi, Mamoru ^a,b  

^a NAGOYA CITY UNIVERSITY   (Japan)

^b AICHI GAKUIN UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Confocal laser scanning microscopy; Cot kinase; Green fluorescent protein; NF B; nuclear translocation; Rat basophilic leukemia (RBL 2H3) cells

Indexed keywords

COT KINASE; FC RECEPTOR; GREEN FLUORESCENT PROTEIN; I KAPPA B KINASE; IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BASOPHIL; BINDING AFFINITY; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; RAT; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE, TUMOR; CELL NUCLEUS; CYTOPLASM; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MAP KINASE KINASE KINASES; MAST CELLS; MICE; NF-KAPPA B; NIH 3T3 CELLS; PROTO-ONCOGENE PROTEINS; RATS; RECEPTORS, IGE;

EID: 33751213423     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.09.002     Document Type: Article

References (40)

1. Amano T., Furuno T., Hirashima N., Ohyama N., and Nakanishi M. Dynamics of intracellular granules with CD63-GFP in rat basophilic leukemia cells. J. Biochem. 129 (2001) 739-744
2. Baldwin A.S. The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14 (1996) 649-693
3. Ballester A., Tobena R., Lisbona C., Calvo V., and Alemany S. Cot kinase regulation of IL-2 production in Jurkat T cells. J. Immunol. 159 (1997) 1613-1618
4. Ballester A., Velasco A., Tobena R., and Alemany S. Cot kinase activates tumor necrosis factor-α gene expression in a cyclosporine A-resistant manner. J. Biol. Chem. 273 (1998) 14099-14106
5. Beinke S., Robinson M.J., Hugunin M., and Ley S.C. Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IκB kinase-induced proteolysis of NF-κB1 p105. Mol. Cell. Biol. 24 (2004) 9658-9667
6. Belich M.P., Salmeron A., Johnson L.H., and Ley S.C. TPL-2 kinase regulates the proteolysis of the NF-κB-inhibitory protein NF-κB1 p105. Nature 397 (1999) 363-368
7. Ceci J.D., Patriotis C.P., Tsatsanis C., Makris A.M., Kovatch R., Swing D.A., Jenkins N.A., Tsichlis P.N., and Copeland N.G. Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation. Genes Dev. 11 (1997) 688-700
8. Chan A.M., Chedid M., McGovern E.S., Popescu N.C., Miki T., and Aaronson S.A. Expression cDNA cloning of a serine kinase transforming gene. Oncogene 8 (1993) 1329-1333
9. Chiariello M., Marinissen M.J., and Gutkind J.S. Multiple mitogen-activated protein kinase signaling pathways connect the Cot oncoprotein to the c-jun promoter and to cellular transformation. Mol. Cell. Biol. 20 (2000) 1747-1758
10. 290 is induced by lipopolysaccharide via an Iκ-B kinase-β-dependent pathway and is required for Tpl2 activation by external signals. J. Biol. Chem. 280 (2005) 20442-20448
11. Cho J., and Tsichlis P.N. Phosphorylation at Thr-290 regulates Tpl2 binding to NF-κB1/p105 and Tpl2 activation and degradation by lipopolysaccharide. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 2350-2355
12. Cohen S., Orian A., and Ciechanover A. Processing of p105 is inhibited by docking of p50 active subunits to the ankyrin repeat domain, and inhibition is alleviated by signaling via the carboxy-terminal phosphorylation/ubiquitin-ligase binding domain. J. Biol. Chem. 276 (2001) 26769-26776
13. Collart M.A., Baeuerle P., and Vassalli P. Regulation of tumor necrosis factor a transcription in macrophages: involvement of four κB-like motifs and of constitutive and inducible forms of NF-κB. Mol. Cell. Biol. 10 (1990) 1498-1506
14. Das S., Cho J., Lambertz I., Kelliher M.A., Eliopoulos A.G., Du K., and Tsichlis P.N. Tpl2/Cot signals activate ERK, JNK, and NF-κB in a cell-type and stimulus-specific manner. J. Biol. Chem. 280 (2005) 23748-23757
15. de Gregorio R., Iniguez M.A., Fresno M., and Alemany S. Cot kinase induces cyclooxygenase-2 expression in T cells through activation of the nuclear factor of activated T cells. J. Biol. Chem. 276 (2001) 27003-27009
16. Dumitru C.D., Ceci J.D., Tsatsanis C., Kontoyiannis D., Stamatakis K., Lin J.H., Patriotis C., Jenkins N.A., Copeland N.G., Kollias G., and Tsichlis P.N. TNF-α induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway. Cell 103 (2000) 1071-1083
17. Eliopoulos A.G., Wang C.C., Dumitru C.D., and Tsichlis P.N. Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40. EMBO J. 22 (2003) 3855-3864
18. Erny K.M., Peli J., Lambert J.F., Muller V., and Diggelmann H. Involvement of the Tpl-2/cot oncogene in MMTV tumorigenesis. Oncogene 13 (1996) 2015-2020
19. Fan C.M., and Maniatis T. Generation of p50 subunit of NF-κB by processing of p105 through an ATP-dependent pathway. Nature 354 (1991) 395-398
20. Furuno T., Hirashima N., Onizawa S., Sagiya N., and Nakanishi M. Nuclear shuttling of mitogen-activated protein (MAP) kinase (extracellular signal-regulated kinase (ERK) 2) was dynamically controlled by MAP/ERK kinase after antigen stimulation in RBL-2H3 cells. J. Immunol. 166 (2001) 4416-4421
21. Ghosh S., May M.J., and Kopp E.B. NF-κB and Rel proteins: evolutionary and conserved mediators of immune responses. Annu. Rev. Immunol. 16 (1998) 225-260
22. Gordon J.R., Burd P.R., and Galli S.J. Mast cells as a source of multifunctional cytokines. Immunol. Today 11 (1990) 458-464
23. Hagemann D., Troppmair J., and Rapp U.R. Cot protooncoprotein activates the dual specificity kinase MEK-1 and SEK-1 and induces differentiation of PC12 cells. Oncogene 18 (1999) 1391-1400
24. Ho S.N., Hunt H.D., Horton R.M., Pullen J.K., and Pease L.R. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77 (1989) 51-59
25. Kane L.P., Mollenauer M.N., Xu Z., Turck C.W., and Weiss A. Akt-dependent phosphorylation specifically regulates Cot induction of NF-κB-dependent transcription. Mol. Cell. Biol. 22 (2002) 5962-5974
26. Kitaura J., Asai K., Maeda-Yamamoto M., Kawakami Y., Kikkawa U., and Kawakami T. Akt-dependent cytokine production in mast cells. J. Exp. Med. 192 (2000) 729-739
27. Lin X., Cunningham J., Mu Y., Geleziunas R., and Greene W.C. The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-κB acting through the NF-κB-inducing kinase and IκB kinases. Immunity 10 (1999) 271-280
28. MacKichan M.L., Logeat F., and Israel A. Phosphorylation of p105 PEST sequences via a redox-insensitive pathway up-regulates processing to p50 NF-κB. J. Biol. Chem. 271 (1996) 6084-6091
29. Mercurio F., DiDonato J.A., Rosette C., and Karin M. p105 and p98 precursor proteins play an activate role in NF-κB-mediated signal transduction. Genes Dev. 7 (1993) 705-718
30. Miyoshi J., Higashi T., Mukai H., Ohuchi T., and Kakunaga T. Structure and transforming potential of the human cot oncogene encoding a putative protein kinase. Mol. Cell. Biol. 11 (1991) 4088-4096
31. Nakamura R., Furuno T., and Nakanishi M. The plasma membrane shuttling of CAPRI is related to regulation of mast cell activation. Biochem. Biophys. Res. Commun. 347 (2006) 363-368
32. Patriotis C., Makris A., Bear S.E., and Tsichlis P.N. Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation. Proc. Natl. Acad. Sci. U.S.A. 90 (1993) 2251-2255
33. Pelletier C., Varin-Blank N., Rivera J., Iannascoli B., Marchand F., David B., Weyer A., and Blank U. FcεRI-mediated induction of TNF-α gene expression in the RBL-2H3 mast cell line: regulation by a novel NF-κB-like nuclear binding complex. J. Immunol. 161 (1998) 4768-4776
34. Rice N.R., MacKichan M.L., and Israel A. The precursor of NF-κB p50 has IκB-like functions. Cell 71 (1992) 243-253
35. Salmeron A., Ahmad T.B., Carlile G.W., Pappin D., Narsimhan R.P., and Ley S.C. Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase. EMBO J. 15 (1996) 817-826
36. Salmeron A., Janzen J., Soneji Y., Bump N., Kamens J., Allen H., and Ley S.C. Direct phosphorylation of NF-κB1 p105 by the IκB kinase complex on serine 927 is essential for signal-induced p105 proteolysis. J. Biol. Chem. 276 (2001) 22215-22222
37. Schlesinger T.K., Fanger G.R., Yujiri T., and Johnson G.L. The Tao of MEKK. Front. Biosci. 3 (1998) 1181-1186
38. Tenjinbaru K., Furuno T., Hirashima N., and Nakanishi M. Nuclear translocation of green fluorescent protein-nuclear factor κB with a distinct lag time in living cells. FEBS Lett. 444 (1999) 1-4
39. 2+ signals in rat basophilic leukemia cells. FEBS Lett. 270 (1990) 115-118
40. Tsatsanis C., Patriotis C., Bear S.E., and Tsichlis P.N. The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 3827-3832