A potent human anti-eotaxin1 antibody, CAT-213: Isolation by phage display and in vitro and in vivo efficacy

Journal of Pharmacology and Experimental Therapeutics

Volumn 319, Issue 3, 2006, Pages 1395-1404

  Main, Sarah ^a   Handy, Rachel ^a   Wilton, Jane ^a   Smith, Stephen ^a   Williams, Liz ^a   Du Fou, Leila ^a   Andrews, John ^a   Conroy, Louise A ^a   May, Richard ^a   Anderson, Ian ^a   Vaughan, Tristan J ^a  

^a MEDIMMUNE LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BERTILIMUMAB; EOTAXIN; IMMUNOGLOBULIN G4; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CAT 212; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; ASTHMA; BINDING AFFINITY; CALCIUM TRANSPORT; CHEMOTAXIS; DRUG EFFICACY; DRUG ISOLATION; DRUG POTENCY; DRUG SPECIFICITY; EOSINOPHILIA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION;

ALGORITHMS; AMINO ACID SEQUENCE; ANTIBODIES, BLOCKING; CALCIUM SIGNALING; CELL SHAPE; CHEMOKINES, CC; CHEMOTAXIS, LEUKOCYTE; CLONING, MOLECULAR; EMBOLISM, AIR; ENZYME-LINKED IMMUNOSORBENT ASSAY; EOSINOPHILS; HUMANS; IMMUNOGLOBULIN G; NEUTRALIZATION TESTS; PEPTIDE LIBRARY;

EID: 33751195753     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.110734     Document Type: Article

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