Basophil responses to chemokines are regulated by both sequential and cooperative receptor signaling

Journal of Immunology

Volumn 165, Issue 12, 2000, Pages 7224-7233

  Heinemann, A ^a   Hartnell, A ^a   Stubbs, V E L ^a   Murakami, K ^a   Soler, D ^a   LaRosa, G ^a   Askenase, P W ^a   Williams, T J ^a   Sabroe, I ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; CHEMOKINE RECEPTOR CCR5; EOTAXIN; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; MONOCYTE CHEMOTACTIC PROTEIN 4; RANTES;

ARTICLE; BASOPHIL; CELL SHAPE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKOCYTE; MONONUCLEAR CELL; PRIORITY JOURNAL; REPRODUCIBILITY; SIGNAL TRANSDUCTION;

EID: 0034671990     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.12.7224     Document Type: Article

References (61)

1. Cell-mediated damage to helminths
2. IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils
3. Ablation of immunity to Amblyomma americanum by anti-basophil serum cooperation between basophils and eosinophils in expression of immunity to ectoparasites (ticks) in guinea pigs
4. Accumulation of basophils and their chemotactic activity in the airways during natural airway narrowing in asthmatic individuals
5. Mast cell and basophil number in the airway correlate with the bronchial responsiveness of asthmatics
6. Basophils, eosinophils, and mast cells in atopic and nonatopic asthma and in latephase allergic reactions in the lung and skin
7. The role of basophils and mast cells in acute and late reactions in the skin
8. Cutaneous basophil hypersensitivity II A light and electron microscopic description
9. Cutaneous basophil hypersensitivity 3 participation of the basophil in hypersensitivity to antigen-antibody complexes, delayed hypersensitivity and contact allergy passive transfer
10. Degranulation of basophilic leukocytes in allergic contact dermatitis reactions in man
11. Antibody-mediated basophil accumulations in cutaneous hypersensitivity reactions of guinea pigs
12. A newly described activity of guinea pig IgG1 antibodies transfer of cutaneous basophil reactions
13. IgE antibody-mediated cutaneous basophil hypersensitivity reactions in guinea pigs
14. Cutaneous basophil hypersensitivity uncovered in the cell transfer of classical tuberculin hypersensitivity
15. Local transfer of delayed hypersensitivity and cutaneous basophil hypersensitivity
16. High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines
17. Eotaxin is a potent chemotaxin for human basophils
18. Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes
19. Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3
20. RANTES is a pro-inflammatory chemokine and chemoattracts basophil cells to extravascular sites
21. Differential response of human basophils and mast cells to recombinant chemokines
22. Monocyte chemotactic protein 1 is a potent activator of human basophils
23. Monocyte chemotactic protein MCP-2 activates human basophil and eosinophil leukocytes similar to MCP-3
24. Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine
25. Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3
26. Production of the novel CC chemokine MCP-4 by airway cells and comparison of its biological activity to other CC chemokines
27. Regulation of cytokine expression and leukotriene formation in human basophils by growth factors, chemokines and chemotactic agonists
28. Regulation of the function of eosinophils and basophils
29. Kinetics of eotaxin generation and its relationship to eosinophil accumulation. In allergic airways disease analysis in a guinea pig model in vivo
30. Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia
31. Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (intrinsic) asthmatics
32. C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects association of eotaxin with early 6-hour eosinophils, and of eotaxin-2 and monocyte chemoattractant protein-4 with the later 24-hour tissue eosinophilia, and relationship to basophils and other C- C chemokines (monocyte chemoattractant protein-3 and RANTES)
33. Cloning and characterization of the guinea pig eosinophil eotaxin receptor, CCR3 blockade using a monoclonal antibody in vivo
34. The kinetics of chemotactic peptide-induced change in F-actin content, F-actin distribution, and the shape of neutrophils
35. Shape changes, exocytosis, and cytosolic free calcium changes in stimulated human eosinophils
36. Relationship of F-actin distribution to development of polar shape in human polymorphonuclear neutrophils
37. 2+-mobilization, actin reorganization, and CD11b upregulation in human eosinophils via a pertussis toxin-sensitive heterotrimeric guanine nucleotlde-binding protein
38. Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix Involvement of cAMP signaling pathway
39. Cellular polarization induced by chemokines a mechanism for leukocyte recruitment
40. A flow cytometric method to measure shape change of human neutrophils
41. Relationship between light scattering in flow cytometry and changes in shape, volume, and actin polymerization in human polymorphonuclear leukocytes
42. Differential regulation of eosinophil chemokine signalling via CCR3 and non-CCR3 pathways
43. Chemokine receptor usage by eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody
44. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells
45. Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide
46. Chemoattractant cross-desensitization of the human neutrophil IL-8 receptor involves receptor internalization and differential receptor subtype regulation
47. Simplified purification of human basophils
48. Interleukin 3 activates human blood basophils via high-affinity binding sites
49. Dendritic cell ontogeny a human dendritic cell lineage of myeloid origin
50. Novel technique for the direct flow cytofluorometric analysis of human basophils in unseparated blood and bone marrow, and the characterization of phenotype and peroxidase of human basophils
51. Cloning, expression, and characterization of the human eosinophil eotaxin receptor
52. Activation of human basophils through the IL-8 receptor
53. RANTES and related chemokines activate human basophil granulocytes through different G protein-coupled receptors
54. RANTES, a monocyte and T lymphocyte chemotactic cytokine releases histamine from human basophils
55. Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line
56. A key role for CC chemokine receptor 4 in lipopolysaccharide-induced endotoxic shock
57. Eotaxin a potent chemoattractant cytokine detected in a guinea-pig model of allergic airways inflammation
58. Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils
59. The CXC-chemokine neutrophil activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2
60. G-protein-coupled receptor heterodimerization modulates receptor function
61. The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2