메뉴 건너뛰기




Volumn 70, Issue 2-3, 2002, Pages 120-129

Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: Molecular mechanism for cancer- and blood-brain barrier-related effects

Author keywords

hsp27; Mobile phone; Non thermal; p38MAPK; Phosphorylation; RF EMF

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; HEAT SHOCK PROTEIN; HSPB1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR PROTEIN;

EID: 0036560770     PISSN: 03014681     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-0436.2002.700207.x     Document Type: Article
Times cited : (345)

References (48)
  • 1
    • 0023192195 scopus 로고
    • Myocardial consequences of reperfusion
    • Becker, L.C. and Ambrosio, G. (1987) Myocardial consequences of reperfusion. Progr Cardiovasc Dis 30:23-44.
    • (1987) Progr Cardiovasc Dis , vol.30 , pp. 23-44
    • Becker, L.C.1    Ambrosio, G.2
  • 2
    • 0030634256 scopus 로고    scopus 로고
    • Stress proteins are not induced in mammalian cells exposed to radiofrequency or microwave radiation
    • Cleary, S.F., Cao, G., Liu, L.M., Egle, P.M. and Shelton, K.R. (1997) Stress proteins are not induced in mammalian cells exposed to radiofrequency or microwave radiation. Bioelectromagnetics 18:499-505.
    • (1997) Bioelectromagnetics , vol.18 , pp. 499-505
    • Cleary, S.F.1    Cao, G.2    Liu, L.M.3    Egle, P.M.4    Shelton, K.R.5
  • 3
    • 0033944777 scopus 로고    scopus 로고
    • Heat shock proteins - Modulators of apoptosis in tumour cells
    • Creagh, E.M., Sheehan, D. and Cotter, T.G. (2000) Heat shock proteins - modulators of apoptosis in tumour cells. Leukemia 14:1161-1173.
    • (2000) Leukemia , vol.14 , pp. 1161-1173
    • Creagh, E.M.1    Sheehan, D.2    Cotter, T.G.3
  • 4
    • 0034963578 scopus 로고    scopus 로고
    • Hsp27 inhibits cytochrome c-mediated caspase activation by sequestering both pro-caspase-3 and cytochrome c
    • Concannon, C.G., Orrenius, S. and Samali, A. (2001) Hsp27 inhibits cytochrome c-mediated caspase activation by sequestering both pro-caspase-3 and cytochrome c. Gene Expression 9:195-201.
    • (2001) Gene Expression , vol.9 , pp. 195-201
    • Concannon, C.G.1    Orrenius, S.2    Samali, A.3
  • 6
    • 0029126861 scopus 로고
    • Exposure of tumor necrosis factor-alpha to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin
    • Deli, M.A., Descamps, L., Dehouck, M.P., Cecchelli, R., Joo, F., Abraham, C.S. and Torpier, G. (1995) Exposure of tumor necrosis factor-alpha to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin. J Neurosci Res 41:717-726.
    • (1995) J Neurosci Res , vol.41 , pp. 717-726
    • Deli, M.A.1    Descamps, L.2    Dehouck, M.P.3    Cecchelli, R.4    Joo, F.5    Abraham, C.S.6    Torpier, G.7
  • 7
    • 0001637870 scopus 로고
    • Permanent cell line expressing human factor VIII-related antigen established by hybridization
    • Edgell, C.J.S., McDonald, C.C. and Graham, J.B. (1983) Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc Natl Acad Sci USA 80:3734-3737.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 3734-3737
    • Edgell, C.J.S.1    McDonald, C.C.2    Graham, J.B.3
  • 9
    • 0030728937 scopus 로고    scopus 로고
    • Effect of global system for mobile communication (GSM) microwave exposure on blood-brain barrier permeability in rat
    • Fritze, K., Sommer, C., Schmitz, B., Mies, G., Hossman, K.A., Kiessling, M. and Wiessner, C. (1997a) Effect of global system for mobile communication (GSM) microwave exposure on blood-brain barrier permeability in rat. Acta Neuropathol 94:465-470.
    • (1997) Acta Neuropathol , vol.94 , pp. 465-470
    • Fritze, K.1    Sommer, C.2    Schmitz, B.3    Mies, G.4    Hossman, K.A.5    Kiessling, M.6    Wiessner, C.7
  • 10
    • 0031587265 scopus 로고    scopus 로고
    • Effect of global system for mobile communication microwave exposure on the genomic response of the rat brain
    • Fritze, K., Wiessner, C., Kuster, N., Sommer, C., Gass, P., Hermann, D.M., Kiessling, M. and Hossmann, K.A. (1997b) Effect of global system for mobile communication microwave exposure on the genomic response of the rat brain. Neuroscience 81:627-639.
    • (1997) Neuroscience , vol.81 , pp. 627-639
    • Fritze, K.1    Wiessner, C.2    Kuster, N.3    Sommer, C.4    Gass, P.5    Hermann, D.M.6    Kiessling, M.7    Hossmann, K.A.8
  • 11
    • 0030785821 scopus 로고    scopus 로고
    • HSP27 as a mediator of confluence-dependent resistance to cell death induced by anticancer drugs
    • Garrido, C., Ottavi, P., Fromentin, A., Hammann, A., Arrigo, A.P., Chauffert, B. and Mehlen, P. (1997) HSP27 as a mediator of confluence-dependent resistance to cell death induced by anticancer drugs. Cancer Res 57:2661-2667.
    • (1997) Cancer Res , vol.57 , pp. 2661-2667
    • Garrido, C.1    Ottavi, P.2    Fromentin, A.3    Hammann, A.4    Arrigo, A.P.5    Chauffert, B.6    Mehlen, P.7
  • 12
    • 0030967687 scopus 로고    scopus 로고
    • Cholecystokinin stimulates heat shock protein 27 phosphorylation in rat pancreas both in vivo and in vitro
    • Groblewski, G.E., Grady, T., Mehta, N., Lambert, H., Logsdon, CD., Landry, J. and Williams, J.A. (1997) Cholecystokinin stimulates heat shock protein 27 phosphorylation in rat pancreas both in vivo and in vitro. Gastroenterology 112:1354-1361.
    • (1997) Gastroenterology , vol.112 , pp. 1354-1361
    • Groblewski, G.E.1    Grady, T.2    Mehta, N.3    Lambert, H.4    Logsdon, C.D.5    Landry, J.6    Williams, J.A.7
  • 13
    • 0030069517 scopus 로고    scopus 로고
    • HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress
    • Huot, J., Houle, F., Spitz, D.R. and Landry, J. (1996) HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress. Cancer Res 56:273-279.
    • (1996) Cancer Res , vol.56 , pp. 273-279
    • Huot, J.1    Houle, F.2    Spitz, D.R.3    Landry, J.4
  • 14
    • 0031057892 scopus 로고    scopus 로고
    • Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells
    • Huot, J., Houle, F., Marceau, F. and Landry, J. (1997) Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells. Circulation Res 80:383-392.
    • (1997) Circulation Res , vol.80 , pp. 383-392
    • Huot, J.1    Houle, F.2    Marceau, F.3    Landry, J.4
  • 15
    • 0032583203 scopus 로고    scopus 로고
    • SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis
    • Huot, J., Houle, F., Rousseau, S., Deschenes, R.G., Shah, G.M. and Landry, J. (1998) SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis. J Cell Biol 143:1361-1373.
    • (1998) J Cell Biol , vol.143 , pp. 1361-1373
    • Huot, J.1    Houle, F.2    Rousseau, S.3    Deschenes, R.G.4    Shah, G.M.5    Landry, J.6
  • 16
    • 0034715983 scopus 로고    scopus 로고
    • Physics and biology of mobile telephony
    • Hyland, G.J. (2000) Physics and biology of mobile telephony. The Lancet 356:1833-1836.
    • (2000) The Lancet , vol.356 , pp. 1833-1836
    • Hyland, G.J.1
  • 17
    • 0029116113 scopus 로고
    • Modulation of the stress-induced synthesis of stress proteins by phorbol ester and okadaic acid
    • Ito, H., Hasegawa, K., Inahuma, Y., Kozawa, O., Asano, T. and Kato, K. (1995) Modulation of the stress-induced synthesis of stress proteins by phorbol ester and okadaic acid. J Biochem 118:629-634.
    • (1995) J Biochem , vol.118 , pp. 629-634
    • Ito, H.1    Hasegawa, K.2    Inahuma, Y.3    Kozawa, O.4    Asano, T.5    Kato, K.6
  • 18
    • 0033914295 scopus 로고    scopus 로고
    • ERK1/2 phosphorylation, induced by electromagnetic fields, diminishes during neoplastic transformation
    • Jin, M., Blank, M. and Goodman, R. (2000) ERK1/2 phosphorylation, induced by electromagnetic fields, diminishes during neoplastic transformation. J Cell Biochem 78:371-379.
    • (2000) J Cell Biochem , vol.78 , pp. 371-379
    • Jin, M.1    Blank, M.2    Goodman, R.3
  • 21
    • 0028346451 scopus 로고
    • Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27
    • Kato, K., Hasegawa, K., Goto, S. and Inaguma, Y. (1994) Dissociation as a result of phosphorylation of an aggregated form of the small stress protein, hsp27. J Biol Chem 269:11274-11278.
    • (1994) J Biol Chem , vol.269 , pp. 11274-11278
    • Kato, K.1    Hasegawa, K.2    Goto, S.3    Inaguma, Y.4
  • 22
    • 0035645312 scopus 로고    scopus 로고
    • Changes in cellular proteins due to environmental non-ionizing radiation. I. Heat shock proteins
    • Kwee, S., Raskmark, P. and Velizarov, S. (2001) Changes in cellular proteins due to environmental non-ionizing radiation. I. Heat shock proteins. Electro-Magnetobiology 20:1061-1072.
    • (2001) Electro-Magnetobiology , vol.20 , pp. 1061-1072
    • Kwee, S.1    Raskmark, P.2    Velizarov, S.3
  • 23
    • 0029365005 scopus 로고
    • Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27
    • Landry, J. and Huot, J. (1995) Modulation of actin dynamics during stress and physiological stimulation by a signaling pathway involving p38 MAP kinase and heat-shock protein 27. Biochem Cell Biol 73:703-707.
    • (1995) Biochem Cell Biol , vol.73 , pp. 703-707
    • Landry, J.1    Huot, J.2
  • 24
    • 0027482463 scopus 로고
    • Modulation of actin microfilament dynamics and fluid phase pinocytosis by phosphorylation of heat shock protein 27
    • Lavoie, J.N., Hickey, E., Weber, L.A. and Landry, J. (1993) Modulation of actin microfilament dynamics and fluid phase pinocytosis by phosphorylation of heat shock protein 27. J Biol Chem 268:24210-24214.
    • (1993) J Biol Chem , vol.268 , pp. 24210-24214
    • Lavoie, J.N.1    Hickey, E.2    Weber, L.A.3    Landry, J.4
  • 25
    • 0033030207 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase inhibitors - Mechanisms and therapeutic potentials
    • Lee, J.C., Kassis, S., Kumar, S., Badger, A. and Adams, J.L. (1999) p38 mitogen-activated protein kinase inhibitors - mechanisms and therapeutic potentials. Pharmacol Ther 82:389-397.
    • (1999) Pharmacol Ther , vol.82 , pp. 389-397
    • Lee, J.C.1    Kassis, S.2    Kumar, S.3    Badger, A.4    Adams, J.L.5
  • 26
    • 0030014643 scopus 로고    scopus 로고
    • Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- And staurosporine-induced cell death
    • Mehlen, P., Schultze-Osthoff, K. and Arrigo, A.P. (1996) Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1-and staurosporine-induced cell death. J Biol Chem 271:16510-16514.
    • (1996) J Biol Chem , vol.271 , pp. 16510-16514
    • Mehlen, P.1    Schultze-Osthoff, K.2    Arrigo, A.P.3
  • 27
    • 0034114721 scopus 로고    scopus 로고
    • Exposure to low-frequency electromagnetic fields does not alter HSP70 expression or HSF-HSE. Binding in HL60 cells
    • Morehouse, C.A. and Owen, R.D. (2000) Exposure to low-frequency electromagnetic fields does not alter HSP70 expression or HSF-HSE. binding in HL60 cells. Radiat Res 153:658-662.
    • (2000) Radiat Res , vol.153 , pp. 658-662
    • Morehouse, C.A.1    Owen, R.D.2
  • 28
    • 0032865573 scopus 로고    scopus 로고
    • On the assumption of negligible heat diffusion during the thermal measurement of a non-uniform specific absorption rate
    • Moros, E.G. and Pickard, W.F. (1999) On the assumption of negligible heat diffusion during the thermal measurement of a non-uniform specific absorption rate. Radiation Res 152:312-320.
    • (1999) Radiation Res , vol.152 , pp. 312-320
    • Moros, E.G.1    Pickard, W.F.2
  • 29
    • 0025651842 scopus 로고
    • Microwave irradiation of rats at 2.45 GHz activates pinocytotic-like uptake of tracer by capillary endothelial cells of cerebral cortex
    • Neubauer, C., Phelan, A.M., Kues, H. and Lange, D.G. (1990) Microwave irradiation of rats at 2.45 GHz activates pinocytotic-like uptake of tracer by capillary endothelial cells of cerebral cortex. Bioelectromagnetics 11:261-268.
    • (1990) Bioelectromagnetics , vol.11 , pp. 261-268
    • Neubauer, C.1    Phelan, A.M.2    Kues, H.3    Lange, D.G.4
  • 30
    • 0033965158 scopus 로고    scopus 로고
    • The p38 signal transduction pathway: Activation and function
    • Ono, K. and Han, J. (2000) The p38 signal transduction pathway: activation and function. Cell Signalling 12:1-13.
    • (2000) Cell Signalling , vol.12 , pp. 1-13
    • Ono, K.1    Han, J.2
  • 32
    • 0030868571 scopus 로고    scopus 로고
    • Basolateral membrane-associated 27-kDa heat shock protein and microfilament polymerization
    • Piotrowicz, R.S. and Levin, E.G. (1997) Basolateral membrane-associated 27-kDa heat shock protein and microfilament polymerization. J Biol Chem 272:25920-25927.
    • (1997) J Biol Chem , vol.272 , pp. 25920-25927
    • Piotrowicz, R.S.1    Levin, E.G.2
  • 33
    • 0031003038 scopus 로고    scopus 로고
    • The 27-kDa shock protein facilitates basic fibroblast growth factor release from endothelial cells
    • Piotrowicz, R.S., Martin, J.L., Dillman, W.H. and Levin, E.G. (1997) The 27-kDa shock protein facilitates basic fibroblast growth factor release from endothelial cells. J Biol Chem 272:7042-7047.
    • (1997) J Biol Chem , vol.272 , pp. 7042-7047
    • Piotrowicz, R.S.1    Martin, J.L.2    Dillman, W.H.3    Levin, E.G.4
  • 36
    • 0033516660 scopus 로고    scopus 로고
    • Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation
    • Rogalla, T., Ehrnsperger, M., Preville, X., Kotlyarov, A., Lutsch, G., Ducasse, C., Paul, C., Wieske, M., Arrigo, A.P., Buchner, J. and Gaestel, M. (1999) Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation. J Biol Chem 274:18947-18956.
    • (1999) J Biol Chem , vol.274 , pp. 18947-18956
    • Rogalla, T.1    Ehrnsperger, M.2    Preville, X.3    Kotlyarov, A.4    Lutsch, G.5    Ducasse, C.6    Paul, C.7    Wieske, M.8    Arrigo, A.P.9    Buchner, J.10    Gaestel, M.11
  • 38
    • 0028325167 scopus 로고
    • Permeability of the blood-brain barrier induced by 915 MHz electromagnetic radiation, continuous wave and modulated at 8, 16, 50, and 200 Hz
    • Salford, L.G., Brun, A., Sturesson, K., Eberhard, J.L. and Persson, B.R. (1994) Permeability of the blood-brain barrier induced by 915 MHz electromagnetic radiation, continuous wave and modulated at 8, 16, 50, and 200 Hz. Microsc Res Tech 15:535-542.
    • (1994) Microsc Res Tech , vol.15 , pp. 535-542
    • Salford, L.G.1    Brun, A.2    Sturesson, K.3    Eberhard, J.L.4    Persson, B.R.5
  • 41
    • 0033567291 scopus 로고    scopus 로고
    • The stress-activated protein kinase pathways
    • Tibbles, L.A. and Woodgett, J.R. (1999) The stress-activated protein kinase pathways. Cell Mol Life Sci 55:1230-1254.
    • (1999) Cell Mol Life Sci , vol.55 , pp. 1230-1254
    • Tibbles, L.A.1    Woodgett, J.R.2
  • 42
    • 0034218682 scopus 로고    scopus 로고
    • Biological and morphological effects on the brain after exposure of rats to a 1439MHz TDMA field
    • Tsurita, G., Nagawa, H., Ueno, S., Watanabe, S. and Taki, M. (2000) Biological and morphological effects on the brain after exposure of rats to a 1439MHz TDMA field. Bioelectromagnetics 21:364-371.
    • (2000) Bioelectromagnetics , vol.21 , pp. 364-371
    • Tsurita, G.1    Nagawa, H.2    Ueno, S.3    Watanabe, S.4    Taki, M.5
  • 44
    • 0035896560 scopus 로고    scopus 로고
    • Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress
    • Volonte, D., Galbiati, F., Pestell, R.G. and Lisanti, M.P. (2001) Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14)) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress. J Biol Chem 276:8094-8103.
    • (2001) J Biol Chem , vol.276 , pp. 8094-8103
    • Volonte, D.1    Galbiati, F.2    Pestell, R.G.3    Lisanti, M.P.4
  • 45
    • 0032785561 scopus 로고    scopus 로고
    • Induction of stress proteins in human endothelial cells by heavy metal ions and heat shock
    • Wagner, M., Hermanns, I., Bittinger, F. and Kirkpartick, C.J. (1999) Induction of stress proteins in human endothelial cells by heavy metal ions and heat shock. Am J Physiol 277:L1026-L1033.
    • (1999) Am J Physiol , vol.277
    • Wagner, M.1    Hermanns, I.2    Bittinger, F.3    Kirkpartick, C.J.4
  • 46
    • 0035027272 scopus 로고    scopus 로고
    • Electromagnetic field effects: Changes in protein phosphorylation in the Jurkat E6.1 cell line
    • Wetzel, B.J., Nindl, G., Vesper, D.N., Swez, J.A., Jasti, A.C. and Johnson, M.T. (2001) Electromagnetic field effects: changes in protein phosphorylation in the Jurkat E6.1 cell line. Biomed Sci Instrum 37:203-208.
    • (2001) Biomed Sci Instrum , vol.37 , pp. 203-208
    • Wetzel, B.J.1    Nindl, G.2    Vesper, D.N.3    Swez, J.A.4    Jasti, A.C.5    Johnson, M.T.6
  • 47
    • 0033748270 scopus 로고    scopus 로고
    • Lyn and syk tyrosine kinases are not activated in B-lineage lymphoid cells exposed to low-energy electromagnetic fields
    • Woods, M., Bobanovic, F., Brown, D. and Alexander, D.R. (2000) Lyn and syk tyrosine kinases are not activated in B-lineage lymphoid cells exposed to low-energy electromagnetic fields. FASEB J 14:2284-2290.
    • (2000) FASEB J , vol.14 , pp. 2284-2290
    • Woods, M.1    Bobanovic, F.2    Brown, D.3    Alexander, D.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.