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Volumn 66, Issue 12, 2006, Pages 1338-1353

Down-regulation of torp4a, encoding the Drosophila homologue of torsinA, results in increased neuronal degeneration

Author keywords

Neurodegeneration AP 3; Pigment granule; Torp4A; TorsinA

Indexed keywords

2 AMINO 3 PHOSPHONOPROPIONIC ACID; CHAPERONE; MYOSIN; PROTEIN TORP4A; TORSIN A; UNCLASSIFIED DRUG;

EID: 33750818947     PISSN: 00223034     EISSN: 10974695     Source Type: Journal    
DOI: 10.1002/neu.20313     Document Type: Article
Times cited : (36)

References (66)
  • 2
    • 0035800504 scopus 로고    scopus 로고
    • Development. Dicing up RNAs
    • Ambros V. 2001. Development. Dicing up RNAs. Science 293:811-813.
    • (2001) Science , vol.293 , pp. 811-813
    • Ambros, V.1
  • 3
    • 0036830228 scopus 로고    scopus 로고
    • The neuropathogenic contributions of lysosomal dysfunction
    • Bahr BA, Bendiske J. 2002. The neuropathogenic contributions of lysosomal dysfunction. J Neurochem 83:481-489.
    • (2002) J Neurochem , vol.83 , pp. 481-489
    • Bahr, B.A.1    Bendiske, J.2
  • 4
    • 0019731694 scopus 로고
    • Staging the metamorphosis of Drosophila melanogaster
    • Bainbridge SP, Bownes M. 1981. Staging the metamorphosis of Drosophila melanogaster. J Embryol Exp Morphol 66:57-80.
    • (1981) J Embryol Exp Morphol , vol.66 , pp. 57-80
    • Bainbridge, S.P.1    Bownes, M.2
  • 5
    • 0035202870 scopus 로고    scopus 로고
    • The Caenorhabditis elegans polarity gene ooc-5 encodes a Torsin-related protein of the AAA ATPase superfamily
    • Basham SE, Rose LS. 2001. The Caenorhabditis elegans polarity gene ooc-5 encodes a Torsin-related protein of the AAA ATPase superfamily. Development 128:4645-4656.
    • (2001) Development , vol.128 , pp. 4645-4656
    • Basham, S.E.1    Rose, L.S.2
  • 6
    • 1942489341 scopus 로고    scopus 로고
    • Spatial pattern of nonmuscle myosin-II distribution during the development of the Drosophila compound eye and implications for retinal morphogenesis
    • Baumann O. 2004. Spatial pattern of nonmuscle myosin-II distribution during the development of the Drosophila compound eye and implications for retinal morphogenesis. Dev Biol 269:519-533.
    • (2004) Dev Biol , vol.269 , pp. 519-533
    • Baumann, O.1
  • 7
    • 29444455075 scopus 로고    scopus 로고
    • Drosophila as a model for human neurodegenerative disease
    • Bilen J, Bonini NM. 2005. Drosophila as a model for human neurodegenerative disease. Annu Rev Genet 39:153-171.
    • (2005) Annu Rev Genet , vol.39 , pp. 153-171
    • Bilen, J.1    Bonini, N.M.2
  • 8
    • 0035887882 scopus 로고    scopus 로고
    • The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes
    • Blumstein J, Faundez V, Nakatsu F, Saito T, Ohno H, Kelly RB. 2001. The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes. J Neurosci 21:8034-8042.
    • (2001) J Neurosci , vol.21 , pp. 8034-8042
    • Blumstein, J.1    Faundez, V.2    Nakatsu, F.3    Saito, T.4    Ohno, H.5    Kelly, R.B.6
  • 9
    • 0035879952 scopus 로고    scopus 로고
    • Neuronal regulation of lifespan: Clues from flies and worms
    • Boulianne GL. 2001. Neuronal regulation of lifespan: Clues from flies and worms. Mech Ageing Dev 122:883-894.
    • (2001) Mech Ageing Dev , vol.122 , pp. 883-894
    • Boulianne, G.L.1
  • 11
    • 0027241846 scopus 로고
    • Defective glia in the Drosophila brain degeneration mutant drop-dead
    • Buchanan RL, Benzer S. 1993. Defective glia in the Drosophila brain degeneration mutant drop-dead. Neuron 10:839-850.
    • (1993) Neuron , vol.10 , pp. 839-850
    • Buchanan, R.L.1    Benzer, S.2
  • 12
    • 5444234179 scopus 로고    scopus 로고
    • RNA interference: From model organisms towards therapy for neural and neuromuscular disorders
    • Buckingham SD, Esmaeili B, Wood M, Sattelle DB. 2004. RNA interference: From model organisms towards therapy for neural and neuromuscular disorders. Hum Mol Genet 13 (Suppl 2):R275-R288.
    • (2004) Hum Mol Genet , vol.13 , Issue.SUPPL. 2
    • Buckingham, S.D.1    Esmaeili, B.2    Wood, M.3    Sattelle, D.B.4
  • 13
    • 0037319121 scopus 로고    scopus 로고
    • Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins
    • Caldwell GA, Cao S, Sexton EG, Gelwix CC, Bevel JP, Caldwell KA. 2003. Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins. Hum Mol Genet 12:307-319.
    • (2003) Hum Mol Genet , vol.12 , pp. 307-319
    • Caldwell, G.A.1    Cao, S.2    Sexton, E.G.3    Gelwix, C.C.4    Bevel, J.P.5    Caldwell, K.A.6
  • 14
    • 0035313837 scopus 로고    scopus 로고
    • Gene silencing by double-stranded RNA
    • Carthew RW. 2001. Gene silencing by double-stranded RNA. Curr Opin Cell Biol 13:244-248.
    • (2001) Curr Opin Cell Biol , vol.13 , pp. 244-248
    • Carthew, R.W.1
  • 15
    • 29144446026 scopus 로고    scopus 로고
    • Dystonia and the nuclear envelope
    • Cookson MR, Clarimon J. 2005. Dystonia and the nuclear envelope. Neuron 48:875-877.
    • (2005) Neuron , vol.48 , pp. 875-877
    • Cookson, M.R.1    Clarimon, J.2
  • 16
    • 27744567561 scopus 로고    scopus 로고
    • Generation and characterization of Dyt1 δGAG knock-in mouse as a model for early-onset dystonia
    • Dang MT, Yokoi F, McNaught KS, Jengelley TA, Jackson T, Li J, Li Y. 2005. Generation and characterization of Dyt1 δGAG knock-in mouse as a model for early-onset dystonia. Exp Neurol 196:452-463.
    • (2005) Exp Neurol , vol.196 , pp. 452-463
    • Dang, M.T.1    Yokoi, F.2    McNaught, K.S.3    Jengelley, T.A.4    Jackson, T.5    Li, J.6    Li, Y.7
  • 21
    • 0035736259 scopus 로고    scopus 로고
    • Organelle-specific initiation of cell death pathways
    • Ferri KF, Kroemer G. 2001. Organelle-specific initiation of cell death pathways. Nat Cell Biol 3:E255-E263.
    • (2001) Nat Cell Biol , vol.3
    • Ferri, K.F.1    Kroemer, G.2
  • 22
    • 0036337354 scopus 로고    scopus 로고
    • Commissureless is required both in commissural neurones and midline cells for axon guidance across the midline
    • Georgiou M, Tear G. 2002. Commissureless is required both in commissural neurones and midline cells for axon guidance across the midline. Development 129:2947-2956.
    • (2002) Development , vol.129 , pp. 2947-2956
    • Georgiou, M.1    Tear, G.2
  • 23
    • 1642433201 scopus 로고    scopus 로고
    • Mislocalization to the nuclear envelope: An effect of the dystonia-causing torsinA mutation
    • Goodchild RE, Dauer WT. 2004. Mislocalization to the nuclear envelope: An effect of the dystonia-causing torsinA mutation. Proc Natl Acad Sci USA 101:847-852.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 847-852
    • Goodchild, R.E.1    Dauer, W.T.2
  • 24
    • 29144460260 scopus 로고    scopus 로고
    • Loss of the dystonia-associated protein TorsinA selectively disrupts the neuronal nuclear envelope
    • Goodchild RE, Kimn CE, Dauer WT. 2005. Loss of the dystonia-associated protein TorsinA selectively disrupts the neuronal nuclear envelope. Neuron 48:923-932.
    • (2005) Neuron , vol.48 , pp. 923-932
    • Goodchild, R.E.1    Kimn, C.E.2    Dauer, W.T.3
  • 26
    • 0031953263 scopus 로고    scopus 로고
    • Second-site noncomplementation identifies genomic regions required for Drosophila nonmuscle myosin function during morphogenesis
    • Halsell SR, Kiehart DP. 1998. Second-site noncomplementation identifies genomic regions required for Drosophila nonmuscle myosin function during morphogenesis. Genetics 148:1845-1863.
    • (1998) Genetics , vol.148 , pp. 1845-1863
    • Halsell, S.R.1    Kiehart, D.P.2
  • 29
    • 0032126699 scopus 로고    scopus 로고
    • Mutation in AP-3 6 in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles
    • Kantheti P, Qiao X, Diaz ME, Peden AA, Meyer GE, Carskadon SL, Kapfhamer D, et al. 1998. Mutation in AP-3 6 in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles. Neuron 21:111-122.
    • (1998) Neuron , vol.21 , pp. 111-122
    • Kantheti, P.1    Qiao, X.2    Diaz, M.E.3    Peden, A.A.4    Meyer, G.E.5    Carskadon, S.L.6    Kapfhamer, D.7
  • 30
    • 5744240629 scopus 로고    scopus 로고
    • A Drosophila model of early onset torsion dystonia suggests impairment in TGF-β signaling
    • Koh YH, Rehfeld K, Ganetzky B. 2004. A Drosophila model of early onset torsion dystonia suggests impairment in TGF-β signaling. Hum Mol Genet 13:2019-2030.
    • (2004) Hum Mol Genet , vol.13 , pp. 2019-2030
    • Koh, Y.H.1    Rehfeld, K.2    Ganetzky, B.3
  • 31
    • 0035856869 scopus 로고    scopus 로고
    • Immunocytochemical characterization of torsin proteins in mouse brain
    • Konakova M, Pulst SM. 2001. Immunocytochemical characterization of torsin proteins in mouse brain. Brain Res 922:1-8.
    • (2001) Brain Res , vol.922 , pp. 1-8
    • Konakova, M.1    Pulst, S.M.2
  • 32
    • 2942651986 scopus 로고    scopus 로고
    • GAL4 causes developmental defects and apoptosis when expressed in the developing eye of Drosophila melanogaster
    • Kramer JM, Staveley BE. 2003. GAL4 causes developmental defects and apoptosis when expressed in the developing eye of Drosophila melanogaster. Genet Mol Res 2:43-47.
    • (2003) Genet Mol Res , vol.2 , pp. 43-47
    • Kramer, J.M.1    Staveley, B.E.2
  • 33
    • 0347284276 scopus 로고    scopus 로고
    • TorsinA, the gene linked to early-onset dystonia, is upregulated by the dopaminergic toxin MPTP in mice
    • Kuner R, Teismann P, Trutzel A, Nairn J, Richter A, Schmidt N, Bach A, et al. 2004. TorsinA, the gene linked to early-onset dystonia, is upregulated by the dopaminergic toxin MPTP in mice. Neurosci Lett 355:126-130.
    • (2004) Neurosci Lett , vol.355 , pp. 126-130
    • Kuner, R.1    Teismann, P.2    Trutzel, A.3    Nairn, J.4    Richter, A.5    Schmidt, N.6    Bach, A.7
  • 35
    • 0034623158 scopus 로고    scopus 로고
    • Torsin a and its torsion dystonia-associated mutant forms are lumenal glycoproteins that exhibit distinct subcellular localizations
    • Kustedjo K, Bracey MH, Cravatt BF. 2000. Torsin A and its torsion dystonia-associated mutant forms are lumenal glycoproteins that exhibit distinct subcellular localizations. J Biol Chem 275:27933-27939.
    • (2000) J Biol Chem , vol.275 , pp. 27933-27939
    • Kustedjo, K.1    Bracey, M.H.2    Cravatt, B.F.3
  • 36
    • 2942715942 scopus 로고    scopus 로고
    • Excessive myosin activity in mbs mutants causes photoreceptor movement out of the Drosophila eye disc epithelium
    • Lee A, Treisman JE. 2004. Excessive myosin activity in mbs mutants causes photoreceptor movement out of the Drosophila eye disc epithelium. Mol Biol Cell 15:3285-3295.
    • (2004) Mol Biol Cell , vol.15 , pp. 3285-3295
    • Lee, A.1    Treisman, J.E.2
  • 38
    • 0042326841 scopus 로고    scopus 로고
    • Characterization of human torsinA and its dystonia-associated mutant form
    • Liu Z, Zotkiewska A, Zolkiewski M. 2003. Characterization of human torsinA and its dystonia-associated mutant form. Biochem J 374:117-122.
    • (2003) Biochem J , vol.374 , pp. 117-122
    • Liu, Z.1    Zotkiewska, A.2    Zolkiewski, M.3
  • 39
    • 0032404540 scopus 로고    scopus 로고
    • Not just pretty eyes: Drosophila eye-colour mutations and lysosomal delivery
    • Lloyd V, Ramaswami M, Kramer H. 1998. Not just pretty eyes: Drosophila eye-colour mutations and lysosomal delivery. Trends Cell Biol 8:257-259.
    • (1998) Trends Cell Biol , vol.8 , pp. 257-259
    • Lloyd, V.1    Ramaswami, M.2    Kramer, H.3
  • 40
    • 12144291154 scopus 로고    scopus 로고
    • Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor 1(2)tid, is critical for early embryonic development and cell survival
    • Lo JF, Hayashi M, Woo-Kim S, Tian B, Huang JF, Fearns C, Takayama S, et al. 2004. Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor 1(2)tid, is critical for early embryonic development and cell survival. Mol Cell Biol 24:2226-2236.
    • (2004) Mol Cell Biol , vol.24 , pp. 2226-2236
    • Lo, J.F.1    Hayashi, M.2    Woo-Kim, S.3    Tian, B.4    Huang, J.F.5    Fearns, C.6    Takayama, S.7
  • 42
    • 0142116349 scopus 로고    scopus 로고
    • Lysosomes and brain aging in mammals
    • Lynch G, Bi X. 2003. Lysosomes and brain aging in mammals. Neurochem Res 28:1725-1734.
    • (2003) Neurochem Res , vol.28 , pp. 1725-1734
    • Lynch, G.1    Bi, X.2
  • 43
    • 0036846119 scopus 로고    scopus 로고
    • TorsinA and heat shock proteins act as molecular chaperones: Suppression of α-synuclein aggregation
    • McLean PJ, Kawamata H, Sheriff S, Hewett J, Sharma N, Ueda K, Breakefield XO, et al. 2002. TorsinA and heat shock proteins act as molecular chaperones: Suppression of α-synuclein aggregation. J Neurochem 83:846-854.
    • (2002) J Neurochem , vol.83 , pp. 846-854
    • McLean, P.J.1    Kawamata, H.2    Sheriff, S.3    Hewett, J.4    Sharma, N.5    Ueda, K.6    Breakefield, X.O.7
  • 45
    • 0032590055 scopus 로고    scopus 로고
    • Defective expression of the mu3 subunit of the AP-3 adaptor complex in the Drosophila pigmentation mutant carmine
    • Mullins C, Hartnell LM, Wassarman DA, Bonifacino JS. 1999. Defective expression of the mu3 subunit of the AP-3 adaptor complex in the Drosophila pigmentation mutant carmine. Mol Gen Genet 262:401-412.
    • (1999) Mol Gen Genet , vol.262 , pp. 401-412
    • Mullins, C.1    Hartnell, L.M.2    Wassarman, D.A.3    Bonifacino, J.S.4
  • 47
    • 0034610156 scopus 로고    scopus 로고
    • Drosophila endosomal proteins hook and deep orange regulate synapse size but not synaptic vesicle recycling
    • Narayanan R, Kramer H, Ramaswami M. 2000. Drosophila endosomal proteins hook and deep orange regulate synapse size but not synaptic vesicle recycling. J Neurobiol 45:105-119.
    • (2000) J Neurobiol , vol.45 , pp. 105-119
    • Narayanan, R.1    Kramer, H.2    Ramaswami, M.3
  • 50
    • 0030747460 scopus 로고    scopus 로고
    • Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet
    • Ooi CE, Moreira JE, Dell'Angelica EC, Poy G, Wassarman DA, Bonifacino JS. 1997. Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet. EMBO J 16:4508-4518.
    • (1997) EMBO J , vol.16 , pp. 4508-4518
    • Ooi, C.E.1    Moreira, J.E.2    Dell'Angelica, E.C.3    Poy, G.4    Wassarman, D.A.5    Bonifacino, J.S.6
  • 53
    • 0031698273 scopus 로고    scopus 로고
    • Gal4 in the Drosophila female germline
    • Rorth P. 1998. Gal4 in the Drosophila female germline. Mech Dev 78:113-118.
    • (1998) Mech Dev , vol.78 , pp. 113-118
    • Rorth, P.1
  • 55
    • 0032198135 scopus 로고    scopus 로고
    • A v-SNARE participates in synaptic vesicle formation mediated by the AP3 adaptor complex
    • Salem N, Faundez V, Homg JT, Kelly RB. 1998. A v-SNARE participates in synaptic vesicle formation mediated by the AP3 adaptor complex. Nat Neurosci 1:551-556.
    • (1998) Nat Neurosci , vol.1 , pp. 551-556
    • Salem, N.1    Faundez, V.2    Homg, J.T.3    Kelly, R.B.4
  • 56
    • 11144253549 scopus 로고    scopus 로고
    • Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain
    • Seong E, Wainer BH, Hughes ED, Saunders TL, Burmeister M, Faundez V. 2005. Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain. Mol Biol Cell 16:128-140.
    • (2005) Mol Biol Cell , vol.16 , pp. 128-140
    • Seong, E.1    Wainer, B.H.2    Hughes, E.D.3    Saunders, T.L.4    Burmeister, M.5    Faundez, V.6
  • 57
    • 0035404388 scopus 로고    scopus 로고
    • A close association of torsinA and α-synuclein in Lewy bodies: A fluorescence resonance energy transfer study
    • Sharma N, Hewett J, Ozelius LJ, Ramesh V, McLean PJ, Breakefield XO, Hyman BT. 2001. A close association of torsinA and α-synuclein in Lewy bodies: A fluorescence resonance energy transfer study. Am J Pathol 159:339-344.
    • (2001) Am J Pathol , vol.159 , pp. 339-344
    • Sharma, N.1    Hewett, J.2    Ozelius, L.J.3    Ramesh, V.4    McLean, P.J.5    Breakefield, X.O.6    Hyman, B.T.7
  • 59
    • 0033987354 scopus 로고    scopus 로고
    • Immunohistochemical localization and distribution of torsinA in normal human and rat brain
    • Shashidharan P, Kramer BC, Walker RH, Olanow CW, Brin MF. 2000b. Immunohistochemical localization and distribution of torsinA in normal human and rat brain. Brain Res 853:197-206.
    • (2000) Brain Res , vol.853 , pp. 197-206
    • Shashidharan, P.1    Kramer, B.C.2    Walker, R.H.3    Olanow, C.W.4    Brin, M.F.5
  • 60
    • 0037598597 scopus 로고    scopus 로고
    • Deep-orange and carnation define distinct stages in late endosomal biogenesis in Drosophila melanogaster
    • Sriram V, Krishnan KS, Mayor S. 2003. Deep-orange and carnation define distinct stages in late endosomal biogenesis in Drosophila melanogaster. J Cell Biol 161:593-607.
    • (2003) J Cell Biol , vol.161 , pp. 593-607
    • Sriram, V.1    Krishnan, K.S.2    Mayor, S.3
  • 61
    • 0037329502 scopus 로고    scopus 로고
    • Roles of myosin phosphatase during Drosophila development
    • Tan C, Stronach B, Perrimon N. 2003. Roles of myosin phosphatase during Drosophila development. Development 130:671-681.
    • (2003) Development , vol.130 , pp. 671-681
    • Tan, C.1    Stronach, B.2    Perrimon, N.3
  • 62
    • 0037089085 scopus 로고    scopus 로고
    • The importin-β P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope
    • Timinszky G, Tirian L, Nagy FT, Toth G, Perczel A, Kiss-Laszlo Z, Boros I, et al. 2002. The importin-β P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope. J Cell Sci 115:1675-1687.
    • (2002) J Cell Sci , vol.115 , pp. 1675-1687
    • Timinszky, G.1    Tirian, L.2    Nagy, F.T.3    Toth, G.4    Perczel, A.5    Kiss-Laszlo, Z.6    Boros, I.7
  • 63
    • 0038638036 scopus 로고    scopus 로고
    • TorsinA, microtubules and cell polarity
    • Toninelli GF, Spano P, Memo M. 2003. TorsinA, microtubules and cell polarity. Funct Neurol 18:7-10.
    • (2003) Funct Neurol , vol.18 , pp. 7-10
    • Toninelli, G.F.1    Spano, P.2    Memo, M.3
  • 64
    • 0034632063 scopus 로고    scopus 로고
    • AAA proteins. Lords of the ring
    • Vale RD. 2000. AAA proteins. Lords of the ring. J Cell Biol 150:F13-F19.
    • (2000) J Cell Biol , vol.150
    • Vale, R.D.1
  • 65
    • 0347417016 scopus 로고    scopus 로고
    • Signal integration during development: Insights from the Drosophila eye
    • Voas MG, Rebay I. 2004. Signal integration during development: insights from the Drosophila eye. Dev Dyn 229:162-175.
    • (2004) Dev Dyn , vol.229 , pp. 162-175
    • Voas, M.G.1    Rebay, I.2
  • 66
    • 0141836952 scopus 로고    scopus 로고
    • TorsinA immunoreactivity in inclusion bodies in trinucleotide repeat diseases
    • Walker RH, Good PF, Shashidharan P. 2003. TorsinA immunoreactivity in inclusion bodies in trinucleotide repeat diseases. Mov Disord 18:1041-1044.
    • (2003) Mov Disord , vol.18 , pp. 1041-1044
    • Walker, R.H.1    Good, P.F.2    Shashidharan, P.3


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