Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria

Science

Volumn 277, Issue 5322, 1997, Pages 60-66

  Xia, Di ^a   Yu, Chang An ^b   Kim, Hoeon ^a   Xia, Jia Zhi ^b   Kachurin, Anatoly M ^b   Zhang, Li ^b   Yu, Linda ^b   Deisenhofer, Johann ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMYCIN A1; CYTOCHROME B; DIMER; IRON SULFUR PROTEIN; MYXOTHIAZOL; UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL CELL; ARTICLE; CATTLE; CRYSTAL STRUCTURE; HEART MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; X RAY DIFFRACTION;

ANIMALS; ANTIMYCIN A; BINDING SITES; CATTLE; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME B GROUP; CYTOCHROMES C1; DIMERIZATION; ELECTRON TRANSPORT COMPLEX III; INTRACELLULAR MEMBRANES; IRON; METHACRYLATES; MITOCHONDRIA, HEART; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; THIAZOLES;

EID: 0030867866     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.277.5322.60     Document Type: Article

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71. 1 complex crystals were performed mainly at beamline 7-A of the Stanford Synchrotron Radiation Laboratory. Beamline 4 of ESRF, beamline 7 of the Cornell High Energy Synchrotron Source, and beamline X8A of NSLS also provided beam time. We thank the staffs of synchrotron facilities in the United States and Europe for help; our colleagues at UT Southwestern Medical Center for their support; S. K. Buchanan and L. Esser for discussions; B. S. Smith, D. B. Staber, and S. Kyle for technical assistance; and K. Fischer Lindahl and C. A. Hasemann for criticism of the manuscript. The coordinates have been deposited in the Brookhaven Protein Data Bank (access number 1QCR).