메뉴 건너뛰기




Volumn 20, Issue 6, 2006, Pages 333-342

Tumor microenvironment and drug resistance in hematologic malignancies

Author keywords

CAM DR; Cell adhesion; Drug resistance; EM DR; SM DR; Tumor microenvironment

Indexed keywords

CYTARABINE; DOXORUBICIN; MELPHALAN; MITOXANTRONE; PATUPILONE; PROTEIN ANTIBODY; STABILIZING AGENT; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 4;

EID: 33750631842     PISSN: 0268960X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.blre.2005.08.003     Document Type: Article
Times cited : (130)

References (80)
  • 1
    • 0344825374 scopus 로고    scopus 로고
    • Role of the tumor microenvironment in mediating de novo resistance to drugs and physiological mediators of cell death
    • Hazlehurst L.A., Landowski T.H., and Dalton W.S. Role of the tumor microenvironment in mediating de novo resistance to drugs and physiological mediators of cell death. Oncogene 22 47 (2003) 7396-7402
    • (2003) Oncogene , vol.22 , Issue.47 , pp. 7396-7402
    • Hazlehurst, L.A.1    Landowski, T.H.2    Dalton, W.S.3
  • 2
    • 0032055818 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells
    • Lagneaux L., Delforge A., Bron D., De Bruyn C., and Stryckmans P. Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells. Blood 91 7 (1998) 2387-2396
    • (1998) Blood , vol.91 , Issue.7 , pp. 2387-2396
    • Lagneaux, L.1    Delforge, A.2    Bron, D.3    De Bruyn, C.4    Stryckmans, P.5
  • 3
    • 0037085765 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy
    • Dias S., Choy M., Alitalo K., and Rafii S. Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood 99 6 (2002) 2179-2184
    • (2002) Blood , vol.99 , Issue.6 , pp. 2179-2184
    • Dias, S.1    Choy, M.2    Alitalo, K.3    Rafii, S.4
  • 4
    • 0030020056 scopus 로고    scopus 로고
    • Elevated intracellular level of basic fibroblast growth factor correlates with stage of chronic lymphocytic leukemia and is associated with resistance to fludarabine
    • Menzel T., Rahman Z., Calleja E., et al. Elevated intracellular level of basic fibroblast growth factor correlates with stage of chronic lymphocytic leukemia and is associated with resistance to fludarabine. Blood 87 3 (1996) 1056-1063
    • (1996) Blood , vol.87 , Issue.3 , pp. 1056-1063
    • Menzel, T.1    Rahman, Z.2    Calleja, E.3
  • 5
    • 0033485625 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells
    • Burger J.A., Burger M., and Kipps T.J. Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells. Blood 94 11 (1999) 3658-3667
    • (1999) Blood , vol.94 , Issue.11 , pp. 3658-3667
    • Burger, J.A.1    Burger, M.2    Kipps, T.J.3
  • 6
    • 0023849455 scopus 로고
    • Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas
    • Kawano M., Hirano T., Matsuda T., et al. Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature 332 6159 (1988) 83-85
    • (1988) Nature , vol.332 , Issue.6159 , pp. 83-85
    • Kawano, M.1    Hirano, T.2    Matsuda, T.3
  • 7
    • 0033780886 scopus 로고    scopus 로고
    • Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents
    • Xu W., Liu L., Smith G.C., and Charles G. Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents. Nat Cell Biol 2 6 (2000) 339-345
    • (2000) Nat Cell Biol , vol.2 , Issue.6 , pp. 339-345
    • Xu, W.1    Liu, L.2    Smith, G.C.3    Charles, G.4
  • 8
    • 0033607274 scopus 로고    scopus 로고
    • Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia
    • Jiang X., Lopez A., Holyoake T., Eaves A., and Eaves C. Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia. Proc Natl Acad Sci USA 96 22 (1999) 12804-12809
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.22 , pp. 12804-12809
    • Jiang, X.1    Lopez, A.2    Holyoake, T.3    Eaves, A.4    Eaves, C.5
  • 9
    • 0023887668 scopus 로고
    • Expression of the macrophage colony-stimulating factor and c-fms genes in human acute myeloblastic leukemia cells
    • Rambaldi A., Wakamiya N., Vellenga E., et al. Expression of the macrophage colony-stimulating factor and c-fms genes in human acute myeloblastic leukemia cells. J Clin Invest 81 4 (1988) 1030-1035
    • (1988) J Clin Invest , vol.81 , Issue.4 , pp. 1030-1035
    • Rambaldi, A.1    Wakamiya, N.2    Vellenga, E.3
  • 10
    • 0023108264 scopus 로고
    • Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in acute myeloblastic leukemia
    • Young D.C., Wagner K., and Griffin J.D. Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in acute myeloblastic leukemia. J Clin Invest 79 1 (1987) 100-106
    • (1987) J Clin Invest , vol.79 , Issue.1 , pp. 100-106
    • Young, D.C.1    Wagner, K.2    Griffin, J.D.3
  • 11
    • 0942298590 scopus 로고    scopus 로고
    • Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival
    • Novak A.J., Darce J.R., Arendt B.K., et al. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival. Blood 103 2 (2004) 689-694
    • (2004) Blood , vol.103 , Issue.2 , pp. 689-694
    • Novak, A.J.1    Darce, J.R.2    Arendt, B.K.3
  • 12
    • 9144220762 scopus 로고    scopus 로고
    • Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway
    • Kern C., Cornuel J.F., Billard C., et al. Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway. Blood 103 2 (2004) 679-688
    • (2004) Blood , vol.103 , Issue.2 , pp. 679-688
    • Kern, C.1    Cornuel, J.F.2    Billard, C.3
  • 13
    • 0035678875 scopus 로고    scopus 로고
    • Inhibition of JAK kinase activity enhances Fas-mediated apoptosis but reduces cytotoxic activity of topoisomerase II inhibitors in U266 myeloma cells
    • Oshiro M.M., Landowski T.H., Catlett-Falcone R., et al. Inhibition of JAK kinase activity enhances Fas-mediated apoptosis but reduces cytotoxic activity of topoisomerase II inhibitors in U266 myeloma cells. Clin Cancer Res 7 12 (2001) 4262-4271
    • (2001) Clin Cancer Res , vol.7 , Issue.12 , pp. 4262-4271
    • Oshiro, M.M.1    Landowski, T.H.2    Catlett-Falcone, R.3
  • 15
    • 0035020361 scopus 로고    scopus 로고
    • Differential expression of chemokine receptors in B cell malignancies
    • Durig J., Schmucker U., and Duhrsen U. Differential expression of chemokine receptors in B cell malignancies. Leukemia 15 5 (2001) 752-756
    • (2001) Leukemia , vol.15 , Issue.5 , pp. 752-756
    • Durig, J.1    Schmucker, U.2    Duhrsen, U.3
  • 16
    • 0037262287 scopus 로고    scopus 로고
    • Expression and function of chemokine receptors in human multiple myeloma
    • Moller C., Stromberg T., Juremalm M., Nilsson K., and Nilsson G. Expression and function of chemokine receptors in human multiple myeloma. Leukemia 17 1 (2003) 203-210
    • (2003) Leukemia , vol.17 , Issue.1 , pp. 203-210
    • Moller, C.1    Stromberg, T.2    Juremalm, M.3    Nilsson, K.4    Nilsson, G.5
  • 18
    • 0030923575 scopus 로고    scopus 로고
    • Expression of FLT4 and its ligand VEGF-C in acute myeloid leukemia
    • Fielder W., Graeven U., Ergun S., et al. Expression of FLT4 and its ligand VEGF-C in acute myeloid leukemia. Leukemia 11 8 (1997) 1234-1237
    • (1997) Leukemia , vol.11 , Issue.8 , pp. 1234-1237
    • Fielder, W.1    Graeven, U.2    Ergun, S.3
  • 19
    • 0033083962 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies
    • Bellamy W.T., Richter L., Frutiger Y., and Grogan T.M. Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies. Cancer Res 59 3 (1999) 728-733
    • (1999) Cancer Res , vol.59 , Issue.3 , pp. 728-733
    • Bellamy, W.T.1    Richter, L.2    Frutiger, Y.3    Grogan, T.M.4
  • 20
    • 0033861874 scopus 로고    scopus 로고
    • Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration
    • Dias S., Hattori K., Zhu Z., et al. Autocrine stimulation of VEGFR-2 activates human leukemic cell growth and migration. J Clin Invest 106 4 (2000) 511-521
    • (2000) J Clin Invest , vol.106 , Issue.4 , pp. 511-521
    • Dias, S.1    Hattori, K.2    Zhu, Z.3
  • 21
    • 0036530301 scopus 로고    scopus 로고
    • VEGF (165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition
    • Dias S., Shmelkov S.V., Lam G., and Rafii S. VEGF (165) promotes survival of leukemic cells by Hsp90-mediated induction of Bcl-2 expression and apoptosis inhibition. Blood 99 7 (2002) 2532-2540
    • (2002) Blood , vol.99 , Issue.7 , pp. 2532-2540
    • Dias, S.1    Shmelkov, S.V.2    Lam, G.3    Rafii, S.4
  • 22
    • 0030973506 scopus 로고    scopus 로고
    • Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
    • Jeltsch M., Kaipainen A., Joukov V., et al. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 276 5317 (1997) 1423-1425
    • (1997) Science , vol.276 , Issue.5317 , pp. 1423-1425
    • Jeltsch, M.1    Kaipainen, A.2    Joukov, V.3
  • 23
    • 0031045135 scopus 로고    scopus 로고
    • Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic lymphocytic leukemia cell lines resulting in delaying apoptosis
    • Konig A., Menzel T., Lynen S., et al. Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic lymphocytic leukemia cell lines resulting in delaying apoptosis. Leukemia 11 2 (1997) 258-265
    • (1997) Leukemia , vol.11 , Issue.2 , pp. 258-265
    • Konig, A.1    Menzel, T.2    Lynen, S.3
  • 24
    • 0028100605 scopus 로고
    • Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only
    • Brogi E., Wu T., Namiki A., and Isner J.M. Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only. Circulation 90 2 (1994) 649-652
    • (1994) Circulation , vol.90 , Issue.2 , pp. 649-652
    • Brogi, E.1    Wu, T.2    Namiki, A.3    Isner, J.M.4
  • 25
    • 0034667624 scopus 로고    scopus 로고
    • Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1
    • Burger J.A., Tsukada N., Burger M., Zvaifler N.J., Dell'Aquila M., and Kipps T.J. Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. Blood 96 8 (2000) 2655-2663
    • (2000) Blood , vol.96 , Issue.8 , pp. 2655-2663
    • Burger, J.A.1    Tsukada, N.2    Burger, M.3    Zvaifler, N.J.4    Dell'Aquila, M.5    Kipps, T.J.6
  • 26
    • 0028921477 scopus 로고
    • Interleukin-6 in human multiple myeloma
    • Klein B., Zhang X.G., Lu Z.Y., and Bataille R. Interleukin-6 in human multiple myeloma. Blood 85 4 (1995) 863-872
    • (1995) Blood , vol.85 , Issue.4 , pp. 863-872
    • Klein, B.1    Zhang, X.G.2    Lu, Z.Y.3    Bataille, R.4
  • 27
    • 0032984589 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
    • Catlett-Falcone R., Landowski T.H., Oshiro M.M., et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 10 1 (1999) 105-115
    • (1999) Immunity , vol.10 , Issue.1 , pp. 105-115
    • Catlett-Falcone, R.1    Landowski, T.H.2    Oshiro, M.M.3
  • 28
    • 0027417547 scopus 로고
    • Increased and highly stable levels of functional soluble interleukin-6 receptor in sera of patients with monoclonal gammopathy
    • Gaillard J.P., Bataille R., Brailly H., et al. Increased and highly stable levels of functional soluble interleukin-6 receptor in sera of patients with monoclonal gammopathy. Eur J Immunol 23 4 (1993) 820-824
    • (1993) Eur J Immunol , vol.23 , Issue.4 , pp. 820-824
    • Gaillard, J.P.1    Bataille, R.2    Brailly, H.3
  • 30
    • 0028132836 scopus 로고
    • Redox signaling: nitrosylation and related target interactions of nitric oxide
    • Stamler J.S. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 78 6 (1994) 931-936
    • (1994) Cell , vol.78 , Issue.6 , pp. 931-936
    • Stamler, J.S.1
  • 31
    • 0032147236 scopus 로고    scopus 로고
    • B-cell chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity
    • Zhao H., Dugas N., Mathiot C., et al. B-cell chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity. Blood 92 3 (1998) 1031-1043
    • (1998) Blood , vol.92 , Issue.3 , pp. 1031-1043
    • Zhao, H.1    Dugas, N.2    Mathiot, C.3
  • 32
    • 0035496908 scopus 로고    scopus 로고
    • Activation of the nitric oxide synthase pathway represents a key component of tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity on hematologic malignancies
    • Secchiero P., Gonelli A., Celeghini C., et al. Activation of the nitric oxide synthase pathway represents a key component of tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity on hematologic malignancies. Blood 98 7 (2001) 2220-2228
    • (2001) Blood , vol.98 , Issue.7 , pp. 2220-2228
    • Secchiero, P.1    Gonelli, A.2    Celeghini, C.3
  • 33
    • 0034670036 scopus 로고    scopus 로고
    • The molecular biology of chronic myeloid leukemia
    • Deininger M.W., Goldman J.M., and Melo J.V. The molecular biology of chronic myeloid leukemia. Blood 96 10 (2000) 3343-3356
    • (2000) Blood , vol.96 , Issue.10 , pp. 3343-3356
    • Deininger, M.W.1    Goldman, J.M.2    Melo, J.V.3
  • 34
    • 0032533620 scopus 로고    scopus 로고
    • Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: a novel model for chronic myelogenous leukemia
    • Zhang X., and Ren R. Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: a novel model for chronic myelogenous leukemia. Blood 92 10 (1998) 3829-3840
    • (1998) Blood , vol.92 , Issue.10 , pp. 3829-3840
    • Zhang, X.1    Ren, R.2
  • 35
    • 0037111665 scopus 로고    scopus 로고
    • BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin
    • Mayerhofer M., Valent P., Sperr W.R., Griffin J.D., and Sillaber C. BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin. Blood 100 10 (2002) 3767-3775
    • (2002) Blood , vol.100 , Issue.10 , pp. 3767-3775
    • Mayerhofer, M.1    Valent, P.2    Sperr, W.R.3    Griffin, J.D.4    Sillaber, C.5
  • 36
    • 0141705366 scopus 로고    scopus 로고
    • IL-3 receptor signaling is dispensable for BCR-ABL-induced myeloproliferative disease
    • Wong S., McLaughlin J., Cheng D., Shannon K., Robb L., and Witte O.N. IL-3 receptor signaling is dispensable for BCR-ABL-induced myeloproliferative disease. Proc Natl Acad Sci USA 100 20 (2003) 11630-11635
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.20 , pp. 11630-11635
    • Wong, S.1    McLaughlin, J.2    Cheng, D.3    Shannon, K.4    Robb, L.5    Witte, O.N.6
  • 38
    • 11144355586 scopus 로고    scopus 로고
    • BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
    • Moreaux J., Legouffe E., Jourdan E., et al. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Blood 103 8 (2004) 3148-3157
    • (2004) Blood , vol.103 , Issue.8 , pp. 3148-3157
    • Moreaux, J.1    Legouffe, E.2    Jourdan, E.3
  • 39
    • 0035874498 scopus 로고    scopus 로고
    • Numerous growth factors, cytokines, and chemokines are secreted by human CD34 (+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner
    • Majka M., Janowska-Wieczorek A., Ratajczak J., et al. Numerous growth factors, cytokines, and chemokines are secreted by human CD34 (+) cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood 97 10 (2001) 3075-3085
    • (2001) Blood , vol.97 , Issue.10 , pp. 3075-3085
    • Majka, M.1    Janowska-Wieczorek, A.2    Ratajczak, J.3
  • 40
    • 0742289555 scopus 로고    scopus 로고
    • Homing and mobilization of hematopoietic stem cells and hematopoietic cancer cells are mirror image processes, utilizing similar signaling pathways and occurring concurrently: circulating cancer cells constitute an ideal target for concurrent treatment with chemotherapy and antilineage-specific antibodiLeukemia
    • Gazitt Y. Homing and mobilization of hematopoietic stem cells and hematopoietic cancer cells are mirror image processes, utilizing similar signaling pathways and occurring concurrently: circulating cancer cells constitute an ideal target for concurrent treatment with chemotherapy and antilineage-specific antibodiLeukemia. Leukemia 18 1 (2004) 1-10
    • (2004) Leukemia , vol.18 , Issue.1 , pp. 1-10
    • Gazitt, Y.1
  • 41
    • 0042008128 scopus 로고    scopus 로고
    • Survival and proliferation factors of normal and malignant plasma cells
    • Klein B., Tarte K., Jourdan M., et al. Survival and proliferation factors of normal and malignant plasma cells. Int J Hematol 78 2 (2003) 106-113
    • (2003) Int J Hematol , vol.78 , Issue.2 , pp. 106-113
    • Klein, B.1    Tarte, K.2    Jourdan, M.3
  • 42
    • 0042167462 scopus 로고    scopus 로고
    • Mechanisms of cell death and survival in multiple myeloma (MM): Therapeutic implications
    • Chauhan D., and Anderson K.C. Mechanisms of cell death and survival in multiple myeloma (MM): Therapeutic implications. Apoptosis 8 4 (2003) 337-343
    • (2003) Apoptosis , vol.8 , Issue.4 , pp. 337-343
    • Chauhan, D.1    Anderson, K.C.2
  • 43
    • 0038235872 scopus 로고    scopus 로고
    • Interleukin-6, CD45 and the src-kinases in myeloma cell proliferation
    • Ishikawa H., Tsuyama N., Abroun S., et al. Interleukin-6, CD45 and the src-kinases in myeloma cell proliferation. Leuk Lymphoma 44 9 (2003) 1477-1481
    • (2003) Leuk Lymphoma , vol.44 , Issue.9 , pp. 1477-1481
    • Ishikawa, H.1    Tsuyama, N.2    Abroun, S.3
  • 44
    • 0038528630 scopus 로고    scopus 로고
    • The tumor microenvironment: focus on myeloma
    • Dalton W.S. The tumor microenvironment: focus on myeloma. Cancer Treat Rev 29 Suppl 1 (2003) 11-19
    • (2003) Cancer Treat Rev , vol.29 , Issue.SUPPL. 1 , pp. 11-19
    • Dalton, W.S.1
  • 45
    • 0036499140 scopus 로고    scopus 로고
    • Adhesion-mediated intracellular redistribution of c-Fas-associated death domain-like IL-1-converting enzyme-like inhibitory protein-long confers resistance to CD95-induced apoptosis in hematopoietic cancer cell lines
    • Shain K.H., Landowski T.H., and Dalton W.S. Adhesion-mediated intracellular redistribution of c-Fas-associated death domain-like IL-1-converting enzyme-like inhibitory protein-long confers resistance to CD95-induced apoptosis in hematopoietic cancer cell lines. J Immunol 168 5 (2002) 2544-2553
    • (2002) J Immunol , vol.168 , Issue.5 , pp. 2544-2553
    • Shain, K.H.1    Landowski, T.H.2    Dalton, W.S.3
  • 46
    • 0035885933 scopus 로고    scopus 로고
    • Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells
    • Hazlehurst L.A., Valkov N., Wisner L., et al. Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells. Blood 98 6 (2001) 1897-1903
    • (2001) Blood , vol.98 , Issue.6 , pp. 1897-1903
    • Hazlehurst, L.A.1    Valkov, N.2    Wisner, L.3
  • 47
    • 0036222549 scopus 로고    scopus 로고
    • Sensing the environment: a historical perspective on integrin signal transduction
    • Miranti C.K., and Brugge J.S. Sensing the environment: a historical perspective on integrin signal transduction. Nat Cell Biol 4 4 (2002) E83-E90
    • (2002) Nat Cell Biol , vol.4 , Issue.4
    • Miranti, C.K.1    Brugge, J.S.2
  • 48
    • 0027154853 scopus 로고
    • Expression of multiple beta 1 integrins on circulating monoclonal B cells in patients with multiple myeloma
    • Jensen G.S., Belch A.R., Mant M.J., Ruether B.A., Yacyshyn B.R., and Pilarski L.M. Expression of multiple beta 1 integrins on circulating monoclonal B cells in patients with multiple myeloma. Am J Hematol 43 1 (1993) 29-36
    • (1993) Am J Hematol , vol.43 , Issue.1 , pp. 29-36
    • Jensen, G.S.1    Belch, A.R.2    Mant, M.J.3    Ruether, B.A.4    Yacyshyn, B.R.5    Pilarski, L.M.6
  • 49
    • 0033105537 scopus 로고    scopus 로고
    • Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines
    • Damiano J.S., Cress A.E., Hazlehurst L.A., Shtil A.A., and Dalton W.S. Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines. Blood 93 5 (1999) 1658-1667
    • (1999) Blood , vol.93 , Issue.5 , pp. 1658-1667
    • Damiano, J.S.1    Cress, A.E.2    Hazlehurst, L.A.3    Shtil, A.A.4    Dalton, W.S.5
  • 50
    • 0034009920 scopus 로고    scopus 로고
    • Integrin-mediated drug resistance in multiple myeloma
    • Damiano J.S., and Dalton W.S. Integrin-mediated drug resistance in multiple myeloma. Leuk Lymphoma 38 1-2 (2000) 71-81
    • (2000) Leuk Lymphoma , vol.38 , Issue.1-2 , pp. 71-81
    • Damiano, J.S.1    Dalton, W.S.2
  • 51
    • 0026770377 scopus 로고
    • Integrins: versatility, modulation, and signaling in cell adhesion
    • Hynes R.O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69 1 (1992) 11-25
    • (1992) Cell , vol.69 , Issue.1 , pp. 11-25
    • Hynes, R.O.1
  • 52
    • 0015312069 scopus 로고
    • Effects of intercellular contact on repair of radiation damage
    • Durand R.E., and Sutherland R.M. Effects of intercellular contact on repair of radiation damage. Exp Cell Res 71 1 (1972) 75-80
    • (1972) Exp Cell Res , vol.71 , Issue.1 , pp. 75-80
    • Durand, R.E.1    Sutherland, R.M.2
  • 53
    • 0033800091 scopus 로고    scopus 로고
    • Multicellular resistance: a paradigm for clinical resistance?
    • Desoize B., and Jardillier J. Multicellular resistance: a paradigm for clinical resistance?. Crit Rev Oncol Hematol 36 2-3 (2000) 193-207
    • (2000) Crit Rev Oncol Hematol , vol.36 , Issue.2-3 , pp. 193-207
    • Desoize, B.1    Jardillier, J.2
  • 54
    • 0038369758 scopus 로고    scopus 로고
    • Cell adhesion-mediated drug resistance (CAM-DR) is associated with activation of NF-kappa B (RelB/p50) in myeloma cells
    • Landowski T.H., Olashaw N.E., Agrawal D., and Dalton W.S. Cell adhesion-mediated drug resistance (CAM-DR) is associated with activation of NF-kappa B (RelB/p50) in myeloma cells. Oncogene 22 16 (2003) 2417-2421
    • (2003) Oncogene , vol.22 , Issue.16 , pp. 2417-2421
    • Landowski, T.H.1    Olashaw, N.E.2    Agrawal, D.3    Dalton, W.S.4
  • 55
    • 0030913673 scopus 로고    scopus 로고
    • Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
    • Khwaja A., Rodriguez-Viciana P., Wennstrom S., Warne P.H., and Downward J. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. Embo J 16 10 (1997) 2783-2793
    • (1997) Embo J , vol.16 , Issue.10 , pp. 2783-2793
    • Khwaja, A.1    Rodriguez-Viciana, P.2    Wennstrom, S.3    Warne, P.H.4    Downward, J.5
  • 56
    • 0036229695 scopus 로고    scopus 로고
    • Integrin regulation of growth factor receptors
    • Yamada K.M., and Even-Ram S. Integrin regulation of growth factor receptors. Nat Cell Biol 4 4 (2002) E75-E76
    • (2002) Nat Cell Biol , vol.4 , Issue.4
    • Yamada, K.M.1    Even-Ram, S.2
  • 57
    • 0042696985 scopus 로고    scopus 로고
    • Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis
    • Reginato M.J., Mills K.R., Paulus J.K., et al. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nat Cell Biol 5 8 (2003) 733-740
    • (2003) Nat Cell Biol , vol.5 , Issue.8 , pp. 733-740
    • Reginato, M.J.1    Mills, K.R.2    Paulus, J.K.3
  • 58
    • 10744227500 scopus 로고    scopus 로고
    • Genotypic and phenotypic comparisons of de novo and acquired melphalan resistance in an isogenic multiple myeloma cell line model
    • Hazlehurst L.A., Enkemann S.A., Beam C.A., et al. Genotypic and phenotypic comparisons of de novo and acquired melphalan resistance in an isogenic multiple myeloma cell line model. Cancer Res 63 22 (2003) 7900-7906
    • (2003) Cancer Res , vol.63 , Issue.22 , pp. 7900-7906
    • Hazlehurst, L.A.1    Enkemann, S.A.2    Beam, C.A.3
  • 59
    • 1442332300 scopus 로고    scopus 로고
    • An inhibitor of the EGF receptor family blocks myeloma cell growth factor activity of HB-EGF and potentiates dexamethasone or anti-IL-6 antibody-induced apoptosis
    • Mahtouk K., Jourdan M., De Vos J., et al. An inhibitor of the EGF receptor family blocks myeloma cell growth factor activity of HB-EGF and potentiates dexamethasone or anti-IL-6 antibody-induced apoptosis. Blood 103 5 (2004) 1829-1837
    • (2004) Blood , vol.103 , Issue.5 , pp. 1829-1837
    • Mahtouk, K.1    Jourdan, M.2    De Vos, J.3
  • 60
    • 0034618384 scopus 로고    scopus 로고
    • Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR)
    • Hazlehurst L.A., Damiano J.S., Buyuksal I., Pledger W.J., and Dalton W.S. Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR). Oncogene 19 38 (2000) 4319-4327
    • (2000) Oncogene , vol.19 , Issue.38 , pp. 4319-4327
    • Hazlehurst, L.A.1    Damiano, J.S.2    Buyuksal, I.3    Pledger, W.J.4    Dalton, W.S.5
  • 61
    • 0034142196 scopus 로고    scopus 로고
    • Opposing effects of engagement of integrins and stimulation of cytokine receptors on cell cycle progression of normal human hematopoietic progenitors
    • Jiang Y., Prosper F., and Verfaillie C.M. Opposing effects of engagement of integrins and stimulation of cytokine receptors on cell cycle progression of normal human hematopoietic progenitors. Blood 95 3 (2000) 846-854
    • (2000) Blood , vol.95 , Issue.3 , pp. 846-854
    • Jiang, Y.1    Prosper, F.2    Verfaillie, C.M.3
  • 62
    • 0032588618 scopus 로고    scopus 로고
    • Fibronectin interaction with alpha4beta1 integrin prevents apoptosis in B cell chronic lymphocytic leukemia: correlation with Bcl-2 and Bax
    • de la Fuente M.T., Casanova B., Garcia-Gila M., Silva A., and Garcia-Pardo A. Fibronectin interaction with alpha4beta1 integrin prevents apoptosis in B cell chronic lymphocytic leukemia: correlation with Bcl-2 and Bax. Leukemia 13 2 (1999) 266-274
    • (1999) Leukemia , vol.13 , Issue.2 , pp. 266-274
    • de la Fuente, M.T.1    Casanova, B.2    Garcia-Gila, M.3    Silva, A.4    Garcia-Pardo, A.5
  • 63
    • 0034284302 scopus 로고    scopus 로고
    • Stromal cells regulate survival of B-lineage leukemic cells during chemotherapy
    • Mudry R.E., Fortney J.E., York T., Hall B.M., and Gibson L.F. Stromal cells regulate survival of B-lineage leukemic cells during chemotherapy. Blood 96 5 (2000) 1926-1932
    • (2000) Blood , vol.96 , Issue.5 , pp. 1926-1932
    • Mudry, R.E.1    Fortney, J.E.2    York, T.3    Hall, B.M.4    Gibson, L.F.5
  • 64
    • 0141461414 scopus 로고    scopus 로고
    • Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia
    • Matsunaga T., Takemoto N., Sato T., et al. Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia. Nat Med 9 9 (2003) 1158-1165
    • (2003) Nat Med , vol.9 , Issue.9 , pp. 1158-1165
    • Matsunaga, T.1    Takemoto, N.2    Sato, T.3
  • 65
    • 0028983407 scopus 로고
    • The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression
    • Zhang Z., Vuori K., Reed J.C., and Ruoslahti E. The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. Proc Natl Acad Sci USA 92 13 (1995) 6161-6165
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.13 , pp. 6161-6165
    • Zhang, Z.1    Vuori, K.2    Reed, J.C.3    Ruoslahti, E.4
  • 66
    • 0035958902 scopus 로고    scopus 로고
    • A signaling pathway from the alpha5beta1 and alpha (v)beta3 integrins that elevates bcl-2 transcription
    • Matter M.L., and Ruoslahti E. A signaling pathway from the alpha5beta1 and alpha (v)beta3 integrins that elevates bcl-2 transcription. J Biol Chem 276 30 (2001) 27757-27763
    • (2001) J Biol Chem , vol.276 , Issue.30 , pp. 27757-27763
    • Matter, M.L.1    Ruoslahti, E.2
  • 67
    • 0031708688 scopus 로고    scopus 로고
    • Stem cell factor enhances the adhesion of AML cells to fibronectin and augments fibronectin-mediated anti-apoptotic and proliferative signals
    • Bendall L.J., Makrynikola V., Hutchinson A., Bianchi A.C., Bradstock K.F., and Gottlieb D.J. Stem cell factor enhances the adhesion of AML cells to fibronectin and augments fibronectin-mediated anti-apoptotic and proliferative signals. Leukemia 12 9 (1998) 1375-1382
    • (1998) Leukemia , vol.12 , Issue.9 , pp. 1375-1382
    • Bendall, L.J.1    Makrynikola, V.2    Hutchinson, A.3    Bianchi, A.C.4    Bradstock, K.F.5    Gottlieb, D.J.6
  • 68
    • 0025788512 scopus 로고
    • Functional evidence for three distinct and independently inhibitable adhesion activities mediated by the human integrin VLA-4. Correlation with distinct alpha*4 epitopes
    • Pulido R., Elices M.J., Campanero M.R., et al. Functional evidence for three distinct and independently inhibitable adhesion activities mediated by the human integrin VLA-4. Correlation with distinct alpha*4 epitopes. J Biol Chem 266 16 (1991) 10241-10245
    • (1991) J Biol Chem , vol.266 , Issue.16 , pp. 10241-10245
    • Pulido, R.1    Elices, M.J.2    Campanero, M.R.3
  • 69
    • 0034882278 scopus 로고    scopus 로고
    • Bone marrow stromal cells regulate caspase 3 activity in leukemic cells during chemotherapy
    • Fortney J.E., Zhao W., Wenger S.L., and Gibson L.F. Bone marrow stromal cells regulate caspase 3 activity in leukemic cells during chemotherapy. Leuk Res 25 10 (2001) 901-907
    • (2001) Leuk Res , vol.25 , Issue.10 , pp. 901-907
    • Fortney, J.E.1    Zhao, W.2    Wenger, S.L.3    Gibson, L.F.4
  • 70
    • 0038717067 scopus 로고    scopus 로고
    • Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms
    • Nefedova Y., Landowski T.H., and Dalton W.S. Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms. Leukemia 17 6 (2003) 1175-1182
    • (2003) Leukemia , vol.17 , Issue.6 , pp. 1175-1182
    • Nefedova, Y.1    Landowski, T.H.2    Dalton, W.S.3
  • 71
    • 1942425110 scopus 로고    scopus 로고
    • Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines
    • Nefedova Y., Cheng P., Alsina M., Dalton W.S., and Gabrilovich D.I. Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines. Blood 103 9 (2004) 3503-3510
    • (2004) Blood , vol.103 , Issue.9 , pp. 3503-3510
    • Nefedova, Y.1    Cheng, P.2    Alsina, M.3    Dalton, W.S.4    Gabrilovich, D.I.5
  • 72
    • 0034903932 scopus 로고    scopus 로고
    • Expression of Notch1 and Jagged1 proteins in acute myeloid leukemia cells
    • Tohda S., and Nara N. Expression of Notch1 and Jagged1 proteins in acute myeloid leukemia cells. Leuk Lymphoma 42 3 (2001) 467-472
    • (2001) Leuk Lymphoma , vol.42 , Issue.3 , pp. 467-472
    • Tohda, S.1    Nara, N.2
  • 73
    • 0036566557 scopus 로고    scopus 로고
    • Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma
    • Jundt F., Anagnostopoulos I., Forster R., Mathas S., Stein H., and Dorken B. Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma. Blood 99 9 (2002) 3398-3403
    • (2002) Blood , vol.99 , Issue.9 , pp. 3398-3403
    • Jundt, F.1    Anagnostopoulos, I.2    Forster, R.3    Mathas, S.4    Stein, H.5    Dorken, B.6
  • 74
    • 0025856717 scopus 로고
    • TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
    • Ellisen L.W., Bird J., West D.C., et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66 4 (1991) 649-661
    • (1991) Cell , vol.66 , Issue.4 , pp. 649-661
    • Ellisen, L.W.1    Bird, J.2    West, D.C.3
  • 75
    • 0034888060 scopus 로고    scopus 로고
    • Notch signaling in leukemia
    • Aster J.C., and Pear W.S. Notch signaling in leukemia. Curr Opin Hematol 8 4 (2001) 237-244
    • (2001) Curr Opin Hematol , vol.8 , Issue.4 , pp. 237-244
    • Aster, J.C.1    Pear, W.S.2
  • 76
    • 0035887655 scopus 로고    scopus 로고
    • Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells
    • Cheng P., Zlobin A., Volgina V., et al. Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells. J Immunol 167 8 (2001) 4458-4467
    • (2001) J Immunol , vol.167 , Issue.8 , pp. 4458-4467
    • Cheng, P.1    Zlobin, A.2    Volgina, V.3
  • 77
    • 9444269817 scopus 로고    scopus 로고
    • Houde C, Li Y, Song L, et al. Over-expression of the NOTCH Ligand JAG2 in Malignant Plasma Cells from Multiple Myeloma Patients and Cell Lines. Blood. Aug 3 2004.
  • 78
    • 0028339242 scopus 로고
    • Functional insulin and insulin-like growth factor-1 receptors are preferentially expressed in multiple myeloma cell lines as compared to B-lymphoblastoid cell lines
    • Freund G.G., Kulas D.T., Way B.A., and Mooney R.A. Functional insulin and insulin-like growth factor-1 receptors are preferentially expressed in multiple myeloma cell lines as compared to B-lymphoblastoid cell lines. Cancer Res 54 12 (1994) 3179-3185
    • (1994) Cancer Res , vol.54 , Issue.12 , pp. 3179-3185
    • Freund, G.G.1    Kulas, D.T.2    Way, B.A.3    Mooney, R.A.4
  • 79
    • 0027303072 scopus 로고
    • Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226
    • Freund G.G., Kulas D.T., and Mooney R.A. Insulin and IGF-1 increase mitogenesis and glucose metabolism in the multiple myeloma cell line, RPMI 8226. J Immunol 151 4 (1993) 1811-1820
    • (1993) J Immunol , vol.151 , Issue.4 , pp. 1811-1820
    • Freund, G.G.1    Kulas, D.T.2    Mooney, R.A.3
  • 80
    • 33750610729 scopus 로고    scopus 로고
    • Lin B, Catley L, LeBlanc R, et al. Patupilone (Epothilone B) inhibits growth and survival of multiple myeloma cells in vitro and in vivo. Blood. Sep 14 2004.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.