A homogeneous, solid-phase assay for hepatitis C virus RNA-dependent RNA polymerase

Analytical Biochemistry

Volumn 359, Issue 1, 2006, Pages 106-111

  Wang, Ying Kai ^a   Rigat, Karen L ^a   Roberts, Susan B ^a   Gao, Min ^a  

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

HCV; Hepatitis C virus; High throughput screening; NS5B; RdRp; RNA dependent RNA polymerase; Scintillation proximity assay; Solid phase assay; SPA

Indexed keywords

ANTIVIRAL AGENTS; ENZYMES; SCINTILLATION; VIRUSES;

HEPATITIS C VIRUS; HIGH THROUGHPUT SCREENING; NS5B; RDRP; RNA-DEPENDENT RNA POLYMERASE; SOLID-PHASE;

RNA;

PRIMER DNA; PRIMER RNA; RNA DIRECTED DNA POLYMERASE INHIBITOR; RNA DIRECTED RNA POLYMERASE; RNA DIRECTED RNA POLYMERASE INHIBITOR; STREPTAVIDIN; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

ARTICLE; BIOTINYLATION; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; ENZYMATIC ASSAY; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; HEPATITIS C VIRUS; HIGH THROUGHPUT SCREENING; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; RNA SYNTHESIS; SCINTILLATION; SOLID STATE; STEADY STATE;

HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 33750611621     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2006.09.013     Document Type: Article

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