The substrate activity of (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine diphosphate toward DNA polymerases α, δ and ε

Antiviral Chemistry and Chemotherapy

Volumn 15, Issue 1, 2004, Pages 23-33

  Birkus, Gabriel ^a   Rejman, Dominik ^a   Otmar, Miroslav ^a   Votruba, Ivan ^a   Rosenberg, Ivan ^a   Holy, Antonin ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Cellular DNA polymerases; Cidofovir; HPMPA; HPMPC; Polyomavirus; Vistide

Indexed keywords

9 (3 HYDROXY 2 PHOSPHONOMETHOXYPROPYL)ADENINE; CIDOFOVIR; DNA; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE EPSILON; EXONUCLEASE; PRIMER DNA; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DNA TEMPLATE; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SUBSTRATE COMPLEX; NONHUMAN; POLYOMA VIRUS; PRIORITY JOURNAL; RNA TRANSLATION;

EID: 2542502620     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632020401500103     Document Type: Article

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